BIOLOGY DIRECT, ISSN 1745-6150, 03/2011, Volume 6, Issue 1, pp. 19 - 19
Transposable elements (TEs) were first discovered more than 50 years ago, but were totally ignored for a long time. Over the last few decades they have...
HORIZONTAL TRANSFER | GENETIC-VARIATION | PLANT GENOMES | DNA TRANSPOSONS | DROSOPHILA-MELANOGASTER | RETROTRANSPOSABLE ELEMENTS | BIOLOGY | MARINER TRANSPOSABLE ELEMENT | EVOLUTIONARY DYNAMICS | REPETITIVE DNA | CHROMOSOMAL REARRANGEMENTS | Animals | Humans | DNA Transposable Elements - genetics | Genome - genetics | Selection, Genetic | Evolution, Molecular | Physiological aspects | Molecular evolution | Transposons | Research
HORIZONTAL TRANSFER | GENETIC-VARIATION | PLANT GENOMES | DNA TRANSPOSONS | DROSOPHILA-MELANOGASTER | RETROTRANSPOSABLE ELEMENTS | BIOLOGY | MARINER TRANSPOSABLE ELEMENT | EVOLUTIONARY DYNAMICS | REPETITIVE DNA | CHROMOSOMAL REARRANGEMENTS | Animals | Humans | DNA Transposable Elements - genetics | Genome - genetics | Selection, Genetic | Evolution, Molecular | Physiological aspects | Molecular evolution | Transposons | Research
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Biology Direct, 03/2011, Volume 6
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Genome-wide meta-analysis identifies novel loci associated with parathyroid hormone level
Molecular medicine (Cambridge, Mass.), ISSN 1076-1551, 04/2018, Volume 24, Issue 1, pp. 15 - 9
Background: Parathyroid hormone (PTH) is one of the principal regulators of calcium homeostasis. Although serum PTH level is mostly accounted by genetic...
Parathyroid hormone | Genome-wide association analysis | Meta-analysis | MEDICINE, RESEARCH & EXPERIMENTAL | VITAMIN-D | HYPERPARATHYROIDISM | BONE-MINERAL DENSITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL-CHARACTERIZATION | GTP-BINDING PROTEINS | HEIGHT | CELL BIOLOGY | GENE | METABOLISM | CALCIUM | CHRONIC KIDNEY-DISEASE | Genome-Wide Association Study | Humans | Middle Aged | Adult | Female | Male | Aged | Polymorphism, Single Nucleotide | Genetic Loci | Parathyroid Hormone - blood | Croatia
Parathyroid hormone | Genome-wide association analysis | Meta-analysis | MEDICINE, RESEARCH & EXPERIMENTAL | VITAMIN-D | HYPERPARATHYROIDISM | BONE-MINERAL DENSITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL-CHARACTERIZATION | GTP-BINDING PROTEINS | HEIGHT | CELL BIOLOGY | GENE | METABOLISM | CALCIUM | CHRONIC KIDNEY-DISEASE | Genome-Wide Association Study | Humans | Middle Aged | Adult | Female | Male | Aged | Polymorphism, Single Nucleotide | Genetic Loci | Parathyroid Hormone - blood | Croatia
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2007, Volume 104, Issue 49, pp. 19375 - 19380
Transposable elements are often considered parasitic DNA sequences, able to invade the genome of their host thanks to their self-replicating ability. This...
Genetic transposition | Genetic drift | Transposons | Evolution | Population size | Evolutionary genetics | Genomes | Genetic mutation | Population genetics | Natural selection | Genome evolution | Molecular domestication | HORIZONTAL TRANSFER | population genetics | ARABIDOPSIS-THALIANA | DROSOPHILA-MELANOGASTER | MULTIDISCIPLINARY SCIENCES | genome evolution | SELFISH DNA | molecular domestication | M HYBRID DYSGENESIS | POPULATION-GENETICS | P-ELEMENTS | COPY NUMBER | REPETITIVE DNA | Genetic Variation | Genetic Drift | Humans | DNA Transposable Elements - genetics | Female | Male | Models, Genetic | Mutation | Evolution, Molecular | Genetic aspects | Insertion elements, DNA | Research | Natural history | Life Sciences | Animal biology | Biological Sciences
Genetic transposition | Genetic drift | Transposons | Evolution | Population size | Evolutionary genetics | Genomes | Genetic mutation | Population genetics | Natural selection | Genome evolution | Molecular domestication | HORIZONTAL TRANSFER | population genetics | ARABIDOPSIS-THALIANA | DROSOPHILA-MELANOGASTER | MULTIDISCIPLINARY SCIENCES | genome evolution | SELFISH DNA | molecular domestication | M HYBRID DYSGENESIS | POPULATION-GENETICS | P-ELEMENTS | COPY NUMBER | REPETITIVE DNA | Genetic Variation | Genetic Drift | Humans | DNA Transposable Elements - genetics | Female | Male | Models, Genetic | Mutation | Evolution, Molecular | Genetic aspects | Insertion elements, DNA | Research | Natural history | Life Sciences | Animal biology | Biological Sciences
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SA44 - THE IDENTIFICATION OF HETEROGENEOUS GENETIC SUBGROUPS FOR MAJOR DEPRESSIVE DISORDER
European Neuropsychopharmacology, ISSN 0924-977X, 2019, Volume 29, pp. S846 - S846
Journal Article
European Neuropsychopharmacology, ISSN 0924-977X, 2019, Volume 29, p. S846
Major Depressive Disorder Working Group of the Psychiatric Genetics Consortium (2) Major Depressive Disorder (MDD) is a leading cause of disability worldwide...
Triglycerides | Comorbidity | Mental illness | Major depressive disorder
Triglycerides | Comorbidity | Mental illness | Major depressive disorder
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 910 - 13
textabstractGenomic analysis of longevity offers the potential to illuminate the biology of human aging. Here, using genome-wide association meta-analysis of...
SURVIVAL | INDIVIDUALS | POPULATION | MULTIDISCIPLINARY SCIENCES | DISEASE | SUSCEPTIBILITY LOCI | RISK | GENETIC-VARIANTS | APOE | BLOOD-PRESSURE | AGE | Body Mass Index | Lung Neoplasms - genetics | Smoking - adverse effects | Coronary Disease - blood | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Life Style | HLA-DRB1 Chains - genetics | Lipoproteins, HDL - blood | Obesity - complications | Humans | Coronary Disease - etiology | Longevity - genetics | HLA-DQ alpha-Chains - genetics | Obesity - genetics | Socioeconomic Factors | Education | Alleles | Insulin Resistance - genetics | Lung Neoplasms - blood | Polymorphism, Single Nucleotide | Lipoprotein(a) - genetics | Body fat | DQA1 protein | Lung cancer | Parents | Cardiovascular disease | Genomes | Body mass index | Apolipoprotein E | Drb1 protein | Aging | Heart diseases | Lipoproteins (high density) | FOXO3 protein | Genomic analysis | Coronary artery | Longevity | Cigarettes | Cigarette smoking | Insulin | Coronary artery disease | Cholesterol | Educational attainment | Genetic variance | Life span | Body mass | Histocompatibility antigen HLA | Smoking
SURVIVAL | INDIVIDUALS | POPULATION | MULTIDISCIPLINARY SCIENCES | DISEASE | SUSCEPTIBILITY LOCI | RISK | GENETIC-VARIANTS | APOE | BLOOD-PRESSURE | AGE | Body Mass Index | Lung Neoplasms - genetics | Smoking - adverse effects | Coronary Disease - blood | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Life Style | HLA-DRB1 Chains - genetics | Lipoproteins, HDL - blood | Obesity - complications | Humans | Coronary Disease - etiology | Longevity - genetics | HLA-DQ alpha-Chains - genetics | Obesity - genetics | Socioeconomic Factors | Education | Alleles | Insulin Resistance - genetics | Lung Neoplasms - blood | Polymorphism, Single Nucleotide | Lipoprotein(a) - genetics | Body fat | DQA1 protein | Lung cancer | Parents | Cardiovascular disease | Genomes | Body mass index | Apolipoprotein E | Drb1 protein | Aging | Heart diseases | Lipoproteins (high density) | FOXO3 protein | Genomic analysis | Coronary artery | Longevity | Cigarettes | Cigarette smoking | Insulin | Coronary artery disease | Cholesterol | Educational attainment | Genetic variance | Life span | Body mass | Histocompatibility antigen HLA | Smoking
Journal Article
Thyroid, ISSN 1050-7256, 06/2019, Volume 29, Issue 6, pp. 886 - 893
Background: Thyroglobulin (Tg) is a 660 kDa iodoglycoprotein that serves as a scaffold for thyroid hormone synthesis. Although a twin study showed that...
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action | ST6GAL1 | thyroglobulin | thyroid | genome-wide association study | THYROID-HORMONE | SIALIC-ACID | MECHANISMS | GLYCOSYLATION | IDENTIFICATION | SERUM THYROGLOBULIN | THYROTROPIN | VARIABILITY | ENDOCRINOLOGY & METABOLISM | EXPRESSION | GENOME-WIDE ASSOCIATION
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action | ST6GAL1 | thyroglobulin | thyroid | genome-wide association study | THYROID-HORMONE | SIALIC-ACID | MECHANISMS | GLYCOSYLATION | IDENTIFICATION | SERUM THYROGLOBULIN | THYROTROPIN | VARIABILITY | ENDOCRINOLOGY & METABOLISM | EXPRESSION | GENOME-WIDE ASSOCIATION
Journal Article
Nature communications, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2069 - 1
In the original version of this Article, the legend in the upper panel of Figure 2 incorrectly read 'paternal imprinting' and should have read 'maternal...
Genetic effects | Methylation | Imprinting
Genetic effects | Methylation | Imprinting
Journal Article
Nature Genetics, ISSN 1061-4036, 11/2015, Volume 47, Issue 11, pp. 1294 - 303
Menopause timing has a substantial impact on infertility and risk of disease, including breast cancer, but the underlying mechanisms are poorly understood. We...
BRCA2 MUTATION CARRIERS | NATURAL MENOPAUSE | BODY-MASS INDEX | LOCI | PREMATURE OVARIAN FAILURE | HOMOLOGOUS RECOMBINATION | WIDE ASSOCIATION | BLOOD-PRESSURE | CELL-TYPES | CHROMOSOMAL INSTABILITY | GENETICS & HEREDITY | Genetic Predisposition to Disease - genetics | Gene Regulatory Networks - genetics | Age Factors | Humans | Menopause - genetics | Middle Aged | Reproduction - genetics | Genotype | Signal Transduction - genetics | Genetic Variation | BRCA1 Protein - genetics | Phenotype | Breast Neoplasms - genetics | Hypothalamus - metabolism | Aging - genetics | DNA Repair | Adult | Female | Models, Genetic | Genome-Wide Association Study - methods | Genomics - methods | Genetic variation | Development and progression | Breast cancer | Genetic aspects | Disease susceptibility | Cellular signal transduction | Health aspects | Identification and classification | Studies | Consortia | Genealogy | Womens health | Genomes | Deoxyribonucleic acid--DNA | Meta-analysis
BRCA2 MUTATION CARRIERS | NATURAL MENOPAUSE | BODY-MASS INDEX | LOCI | PREMATURE OVARIAN FAILURE | HOMOLOGOUS RECOMBINATION | WIDE ASSOCIATION | BLOOD-PRESSURE | CELL-TYPES | CHROMOSOMAL INSTABILITY | GENETICS & HEREDITY | Genetic Predisposition to Disease - genetics | Gene Regulatory Networks - genetics | Age Factors | Humans | Menopause - genetics | Middle Aged | Reproduction - genetics | Genotype | Signal Transduction - genetics | Genetic Variation | BRCA1 Protein - genetics | Phenotype | Breast Neoplasms - genetics | Hypothalamus - metabolism | Aging - genetics | DNA Repair | Adult | Female | Models, Genetic | Genome-Wide Association Study - methods | Genomics - methods | Genetic variation | Development and progression | Breast cancer | Genetic aspects | Disease susceptibility | Cellular signal transduction | Health aspects | Identification and classification | Studies | Consortia | Genealogy | Womens health | Genomes | Deoxyribonucleic acid--DNA | Meta-analysis
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1383 - 13
Parent-of-origin effects (POE) exist when there is differential expression of alleles inherited from the two parents. A genome-wide scan for POE on DNA...
VISUALIZATION | GENERATION SCOTLAND | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | EXPRESSION | EPIGENOME-WIDE ASSOCIATION | GENOME | SCOTTISH FAMILY HEALTH | RESOURCE | REVEALS | AGE | Humans | Middle Aged | Gene Expression Regulation | Genotype | Male | Scotland | DNA Methylation - genetics | Genomic Imprinting - genetics | CpG Islands | Adult | Female | Polymorphism, Single Nucleotide | Quantitative Trait Loci - genetics | Regulators | Parents | Association analysis | Genomes | Single-nucleotide polymorphism | Gene expression | Loci | Quantitative trait loci | Genetic effects | DNA methylation | Methylation | Variation | Gene mapping | Deoxyribonucleic acid--DNA
VISUALIZATION | GENERATION SCOTLAND | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | EXPRESSION | EPIGENOME-WIDE ASSOCIATION | GENOME | SCOTTISH FAMILY HEALTH | RESOURCE | REVEALS | AGE | Humans | Middle Aged | Gene Expression Regulation | Genotype | Male | Scotland | DNA Methylation - genetics | Genomic Imprinting - genetics | CpG Islands | Adult | Female | Polymorphism, Single Nucleotide | Quantitative Trait Loci - genetics | Regulators | Parents | Association analysis | Genomes | Single-nucleotide polymorphism | Gene expression | Loci | Quantitative trait loci | Genetic effects | DNA methylation | Methylation | Variation | Gene mapping | Deoxyribonucleic acid--DNA
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 10964 - 11
The Viking Health Study Shetland is a population-based research cohort of 2,122 volunteer participants with ancestry from the Shetland Isles in northern...
STATEMENT | GENETIC-VARIATION | ORIGIN | POLICY | HERG | KVLQT1 | MULTIDISCIPLINARY SCIENCES | CHANNEL MUTATIONS | SPECTRUM | INFERENCE | Haplotypes | Genetic variance | Phenotypes | Pedigree | Long QT syndrome | Population | Population studies | Single-nucleotide polymorphism | Genomes | Gene polymorphism | Chromosomes
STATEMENT | GENETIC-VARIATION | ORIGIN | POLICY | HERG | KVLQT1 | MULTIDISCIPLINARY SCIENCES | CHANNEL MUTATIONS | SPECTRUM | INFERENCE | Haplotypes | Genetic variance | Phenotypes | Pedigree | Long QT syndrome | Population | Population studies | Single-nucleotide polymorphism | Genomes | Gene polymorphism | Chromosomes
Journal Article
The Economic Journal, ISSN 0013-0133, 12/2013, Volume 123, Issue 573, p. 1279
Using a unique data set merging micro-store level data with grocery markets data, this article provides an empirical analysis of a legislation that had the...
Price regulations | Studies | Retail stores | Resale price maintenance | Legislation
Price regulations | Studies | Retail stores | Resale price maintenance | Legislation
Journal Article
Genome Medicine, ISSN 1756-994X, 03/2017, Volume 9, Issue 1, p. 1
Background: The Generation Scotland: Scottish Family Health Study (GS: SFHS) is a family-based population cohort with DNA, biological samples,...
Heart rate | Haplotype Research Consortium (HRC) | Quantitative trait | Urate | Genetics | Genome-wide association studies (GWAS) | Imputation | Glucose | Electronic health records | VARIANTS | REFERENCE PANEL | LOW-FREQUENCY | LOCI | BLOOD-PRESSURE | SCOTTISH FAMILY HEALTH | HEART | GENETICS & HEREDITY | GLYCEMIC TRAITS | ANALYSES IDENTIFY | ELECTRONIC HEALTH RECORD | Haplotypes | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Fasting | Prospective Studies | Cross-Sectional Studies | Quantitative Trait, Heritable | Genes | Heart Rate - genetics | Humans | Male | Scotland | Blood Glucose - genetics | Female | Polymorphism, Single Nucleotide | Uric Acid - blood | Electronic Health Records | Conduction | Health services | Gout | Cognitive ability | Association analysis | Genomes | Biochemistry | Arthritis | Electronic medical records | Information systems | Datasets | Consortia | Calcium signalling | Body mass index | Language | Quality | Population | Blood pressure | Heart diseases | Deoxyribonucleic acid--DNA | Age | Creatinine | Crystals | Inflammation | Cholesterol | Studies | Ethnicity | Body mass | Alleles | Diabetes | Metabolic disorders
Heart rate | Haplotype Research Consortium (HRC) | Quantitative trait | Urate | Genetics | Genome-wide association studies (GWAS) | Imputation | Glucose | Electronic health records | VARIANTS | REFERENCE PANEL | LOW-FREQUENCY | LOCI | BLOOD-PRESSURE | SCOTTISH FAMILY HEALTH | HEART | GENETICS & HEREDITY | GLYCEMIC TRAITS | ANALYSES IDENTIFY | ELECTRONIC HEALTH RECORD | Haplotypes | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Fasting | Prospective Studies | Cross-Sectional Studies | Quantitative Trait, Heritable | Genes | Heart Rate - genetics | Humans | Male | Scotland | Blood Glucose - genetics | Female | Polymorphism, Single Nucleotide | Uric Acid - blood | Electronic Health Records | Conduction | Health services | Gout | Cognitive ability | Association analysis | Genomes | Biochemistry | Arthritis | Electronic medical records | Information systems | Datasets | Consortia | Calcium signalling | Body mass index | Language | Quality | Population | Blood pressure | Heart diseases | Deoxyribonucleic acid--DNA | Age | Creatinine | Crystals | Inflammation | Cholesterol | Studies | Ethnicity | Body mass | Alleles | Diabetes | Metabolic disorders
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Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank
Translational Psychiatry, ISSN 2158-3188, 12/2018, Volume 8, Issue 1, pp. 9 - 12
Few replicable genetic associations for Major Depressive Disorder (MDD) have been identified. Recent studies of MDD have identified common risk variants by...
POPULATION | GENOTYPE IMPUTATION | PSYCHIATRY | REFERENCE PANEL | GWAS CATALOG | DISORDER | RISK | NEUROTICISM | MAJOR DEPRESSION | LD SCORE REGRESSION | ASSOCIATION | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Middle Aged | Risk Factors | Logistic Models | Male | Scotland - epidemiology | Multifactorial Inheritance | Phenotype | Depressive Disorder, Major - genetics | Biological Specimen Banks | Adult | Female | Aged | Polymorphism, Single Nucleotide | United Kingdom - epidemiology | Genomes
POPULATION | GENOTYPE IMPUTATION | PSYCHIATRY | REFERENCE PANEL | GWAS CATALOG | DISORDER | RISK | NEUROTICISM | MAJOR DEPRESSION | LD SCORE REGRESSION | ASSOCIATION | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Middle Aged | Risk Factors | Logistic Models | Male | Scotland - epidemiology | Multifactorial Inheritance | Phenotype | Depressive Disorder, Major - genetics | Biological Specimen Banks | Adult | Female | Aged | Polymorphism, Single Nucleotide | United Kingdom - epidemiology | Genomes
Journal Article