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1. Full Text Laurent Briollais, Robert G. Bristow, Paul C. Boutros, PRACTICAL consortium, Alexandre R. Zlotta Response
by Briollais, Laurent and Bristow, Robert G and Boutros, Paul C and Zlotta, Alexandre R and PRACTICAL Consortium
JNCI : Journal of the National Cancer Institute, ISSN 0027-8874, 12/2017, Volume 109, Issue 12
Life Sciences & Biomedicine | Oncology | Science & Technology
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2. Full Text VennDiagram: A package for the generation of highly-customizable Venn and Euler diagrams in R
by Chen, Hanbo and Boutros, Paul C
BMC bioinformatics, ISSN 1471-2105, 01/2011, Volume 12, Issue 1, pp. 35 - 35
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Biochemical Research Methods | Science & Technology | Mathematical & Computational Biology | Computer Graphics | Computational Biology - methods | Data Interpretation, Statistical | Software | Study and teaching | Usage | Algorithms | Analysis | Venn diagrams | Computational biology | Medical research | Linux | Bioinformatics | Index Medicus
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3. Full Text The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis
by Barsyte-Lovejoy, Dalia and Lau, Suzanne K and Boutros, Paul C and Khosravi, Fereshteh and Jurisica, Igor and Andrulis, Irene L and Tsao, Ming S and Penn, Linda Z
Cancer research (Chicago, Ill.), ISSN 0008-5472, 05/2006, Volume 66, Issue 10, pp. 5330 - 5337
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Genomic Imprinting | Up-Regulation | Humans | Lung Neoplasms - metabolism | RNA, Messenger - metabolism | Breast - metabolism | RNA, Untranslated - genetics | Breast Neoplasms - metabolism | Proto-Oncogene Proteins c-myc - biosynthesis | Insulin-Like Growth Factor II - genetics | Glioblastoma - genetics | Cell Transformation, Neoplastic - genetics | Insulin-Like Growth Factor II - biosynthesis | Glioblastoma - metabolism | Transcription, Genetic | Acetylation | Gene Expression Regulation, Neoplastic - physiology | Genes, myc - physiology | Lung Neoplasms - genetics | Promoter Regions, Genetic | RNA, Messenger - genetics | Breast - physiology | Rats | Proto-Oncogene Proteins c-myc - metabolism | Animals | Breast Neoplasms - genetics | Histones - genetics | RNA, Untranslated - biosynthesis | RNA, Long Noncoding | Alleles | Cell Line, Tumor | Proto-Oncogene Proteins c-myc - genetics | Histones - metabolism | Index Medicus
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4. Full Text MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability
by Dingar, Dharmendra and Tu, William B and Resetca, Diana and Lourenco, Corey and Tamachi, Aaliya and De Melo, Jason and Houlahan, Kathleen E and Kalkat, Manpreet and Chan, Pak-Kei and Boutros, Paul C and Raught, Brian and Penn, Linda Z
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3502 - 13
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Chromatin - metabolism | RNA-Binding Proteins - genetics | Immunoprecipitation | Humans | Electrophoresis, Gel, Two-Dimensional | Immunoblotting | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | DNA-Binding Proteins - metabolism | Protein Phosphatase 1 - metabolism | Chromatin Immunoprecipitation | Mass Spectrometry | Protein Phosphatase 1 - genetics | Cell Line, Tumor | Proto-Oncogene Proteins c-myc - genetics | Protein Stability | Nuclear Proteins - genetics | RNA-Binding Proteins - metabolism | Binding | Phosphorylation | Chromatin | Deregulation | Transcription | Threonine | Phosphoprotein phosphatase | Serine | RNA-mediated interference | c-Myc protein | Mass spectroscopy | Pharmacology | Dephosphorylation | Myc protein | Phosphatase | Proteins | Regulatory mechanisms (biology) | Proteasomes | Protein phosphatase | Inhibition | Mass spectrometry | Index Medicus
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5. Full Text Optimization and expansion of non-negative matrix factorization
by Lin, Xihui and Boutros, Paul C
BMC bioinformatics, ISSN 1471-2105, 01/2020, Volume 21, Issue 1, pp. 7 - 7
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Biochemical Research Methods | Science & Technology | Mathematical & Computational Biology | Computational Biology - methods | Algorithms | Neoplasms - genetics | Humans | Lung cancer | Decomposition | Factorization | Optimization | Convergence | Datasets | Sparsity | Computer applications | Information processing | Signal processing | Masking | Artificial intelligence | Bioinformatics | Methods | Tumors | Index Medicus | Non-negative matrix factorization | Deconvolution | Imputation
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6. Full Text The path to routine use of genomic biomarkers in the cancer clinic
by Boutros, Paul C
Genome research, ISSN 1088-9051, 10/2015, Volume 25, Issue 10, pp. 1508 - 1513
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Reproducibility of Results | Neoplasms - genetics | Biomarkers, Tumor - analysis | Genomics | Humans | Biomarkers, Tumor - economics | Biomarkers, Tumor - genetics | Neoplasms - diagnosis | Genetic Testing - economics | Genetic Testing - trends | Health Communication | Genetic aspects | Research | Biological markers | Cancer | Index Medicus
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7. Full Text Novel PRKD gene rearrangements and variant fusions in cribriform adenocarcinoma of salivary gland origin
by Weinreb, Ilan and Zhang, Lei and Tirunagari, Laxmi MS and Sung, Yun‐Shao and Chen, Chun‐Liang and Perez‐Ordonez, Bayardo and Clarke, Blaise A and Skalova, Alena and Chiosea, Simion I and Seethala, Raja R and Waggott, Daryl and Boutros, Paul C and How, Christine and Liu, Fei‐Fei and Irish, Jonathan C and Goldstein, David P and Gilbert, Ralph and ud Din, Nasir and Assaad, Adel and Hornick, Jason L and Thompson, Lester DR and Antonescu, Cristina R
Genes chromosomes & cancer, ISSN 1045-2257, 10/2014, Volume 53, Issue 10, pp. 845 - 856
Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Protein Kinase C - genetics | Adenocarcinoma - pathology | Salivary Gland Neoplasms - genetics | Humans | Middle Aged | Male | Young Adult | Adenocarcinoma - metabolism | Protein Isoforms - metabolism | Protein Kinase C - metabolism | Salivary Gland Neoplasms - metabolism | Aged, 80 and over | Adult | Female | Adenocarcinoma - genetics | DEAD-box RNA Helicases - metabolism | Nuclear Proteins - genetics | Cell Line | Gene Fusion | In Situ Hybridization, Fluorescence | Nuclear Proteins - metabolism | Transcription Factors - genetics | Transcription Factors - metabolism | DEAD-box RNA Helicases - genetics | Aged | High-Throughput Nucleotide Sequencing | Salivary Gland Neoplasms - pathology | Salivary Glands - metabolism | Protein Isoforms - genetics | Index Medicus
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8. Full Text Teneurin C-terminal associated peptide (TCAP)-1 modulates dendritic morphology in hippocampal neurons and decreases anxiety-like behaviors in rats
by Tan, Laura A and Al Chawaf, Arij and Vaccarino, Franco J and Boutros, Paul C and Lovejoy, David A
Physiology & behavior, ISSN 0031-9384, 2011, Volume 104, Issue 2, pp. 199 - 204
Psychiatry | Spine density | Anxiety | Teneurin C-terminal associated peptide | Amygdala | Dendritic morphology | Hippocampus | Psychology, Biological | Social Sciences | Life Sciences & Biomedicine | Behavioral Sciences | Psychology | Science & Technology | Silver Staining - methods | Dendrites - drug effects | Dendrites - pathology | Neurons - pathology | Rats, Wistar | Anxiety - physiopathology | Rats | Male | Anxiety - drug therapy | Dendrites - ultrastructure | Hippocampus - pathology | Maze Learning - drug effects | Anxiety - pathology | Behavior, Animal | Animals | Analysis of Variance | Time Factors | Dendritic Spines - drug effects | Dendritic Spines - pathology | Tenascin - administration & dosage | Nerve Tissue Proteins - administration & dosage | Injections, Intraventricular - methods | Disease Models, Animal | Index Medicus
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9. Full Text The Promise and Perils of Sequencing Individual Prostate Cancer Nuclei
by Boutros, Paul C
European urology, ISSN 0302-2838, 11/2018, Volume 74, Issue 5, pp. 560 - 561
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Prostatic Neoplasms | Male | Genomics | Humans | Index Medicus
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10. Full Text The Proteogenomic Landscape of Curable Prostate Cancer
by Sinha, Ankit and Huang, Vincent and Livingstone, Julie and Wang, Jenny and Fox, Natalie S and Kurganovs, Natalie and Ignatchenko, Vladimir and Fritsch, Katharina and Donmez, Nilgun and Heisler, Lawrence E and Shiah, Yu-Jia and Yao, Cindy Q and Alfaro, Javier A and Volik, Stas and Lapuk, Anna and Fraser, Michael and Kron, Ken and Murison, Alex and Lupien, Mathieu and Sahinalp, Cenk and Collins, Colin C and Tetu, Bernard and Masoomian, Mehdi and Berman, David M and van der Kwast, Theodorus and Bristow, Robert G and Kislinger, Thomas and Boutros, Paul C
Cancer cell, ISSN 1535-6108, 03/2019, Volume 35, Issue 3, pp. 414 - 427.e6
genome | prostate cancer | epigenome | transcriptome | multi-omic features | biomarker | proteome | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | Translocation, Genetic | Epigenomics | Prognosis | Proto-Oncogene Proteins c-ets - genetics | Humans | Middle Aged | Male | Gene Expression Profiling | Whole Genome Sequencing | Proteogenomics - methods | Prostatic Neoplasms - genetics | Aged, 80 and over | Biomarkers, Tumor - metabolism | Cell Line, Tumor | Adult | Aged | Biomarkers, Tumor - genetics | Proto-Oncogene Proteins c-ets - metabolism | RNA | Prostate cancer | Analysis | Genomics | Index Medicus
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11. Full Text Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands
by Weinreb, Ilan and Piscuoglio, Salvatore and Martelotto, Luciano G and Waggott, Daryl and Ng, Charlotte K Y and Perez-Ordonez, Bayardo and Harding, Nicholas J and Alfaro, Javier and Chu, Kenneth C and Viale, Agnes and Fusco, Nicola and Da Cruz Paula, Arnaud and Marchio, Caterina and Sakr, Rita A and Lim, Raymond and Thompson, Lester D R and Chiosea, Simion I and Seethala, Raja R and Skalova, Alena and Stelow, Edward B and Fonseca, Isabel and Assaad, Adel and How, Christine and Wang, Jianxin and De Borja, Richard and Chan-Seng-Yue, Michelle and Howlett, Christopher J and Nichols, Anthony C and Wen, Y Hannah and Katabi, Nora and Buchner, Nicholas and Mullen, Laura and Kislinger, Thomas and Wouters, Bradly G and Liu, Fei-Fei and Norton, Larry and McPherson, John D and Rubin, Brian P and Clarke, Blaise A and Weigelt, Britta and Boutros, Paul C and Reis-Filho, Jorge S
Nature genetics, ISSN 1061-4036, 11/2014, Volume 46, Issue 11, pp. 1166 - 1169
Immunohistochemistry | Amino Acid Sequence | NIH 3T3 Cells | Protein Kinase C - genetics | Adenocarcinoma - pathology | Immunoprecipitation | Salivary Gland Neoplasms - genetics | Humans | Models, Molecular | Molecular Sequence Data | Sequence Analysis, DNA | Mutation, Missense - genetics | Microscopy, Confocal | Sequence Alignment | Animals | Mutagenesis | Protein Kinase C - chemistry | Adenocarcinoma - genetics | Mice | Salivary Gland Neoplasms - pathology | Adenocarcinoma | Genetic aspects | Gene mutations | Salivary gland tumors | Health aspects | Protein kinases | Studies | Medical research | Mutation | Kinases | Index Medicus
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