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by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Rao, Arvind and Chen, Chu and Chen, Ken and Chen, Amy and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles E and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Linghua and Wang, Zhining and Wang, Jing and Wang, Timothy and Wang, Min and Yang, Hannah and Yang, Ian and Yang, Ju Dong and Yang, Liming and Zenklusen, Jean C and Zhang, Lizhi and Zhang, Hongxin and Zhang, Jiexin and Zhang, Hongzheng and Zhang, Jiashan (Julia) and Zhang, Wei and Zhang, Hailei and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Index Medicus | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15544 - 15549
Journal Article
by Farshidfar, Farshad and Zheng, Siyuan and Gingras, Marie-Claude and Newton, Yulia and Shih, Juliann and Robertson, A. Gordon and Hinoue, Toshinori and Hoadley, Katherine A and Gibb, Ewan A and Roszik, Jason and Covington, Kyle R and Wu, Ye and Wu, Chia-Chin and Shinbrot, Eve and Stransky, Nicolas and Hegde, Apurva M and Hegde, Apurva and Yang, Ju Dong and Yang, Liming and Reznik, Ed and Sadeghi, Sara and Pedamallu, Chandra Sekhar and Ojesina, Akinyemi I and Hess, Julian M and Auman, J. Todd and Rhie, Suhn K and Bowlby, Reanne and Borad, Mitesh J and Akbani, Rehan and Allotey, Loretta K and Ally, Adrian and Alvaro, Domenico and Andersen, Jesper B and Appelbaum, Elizabeth L and Arora, Arshi and Balasundaram, Miruna and Balu, Saianand and Bardeesy, Nabeel and Bathe, Oliver F and Baylin, Stephen B and Beroukhim, Rameen and Berrios, Mario and Bodenheimer, Tom and Boice, Lori and Bootwalla, Moiz S and Bowen, Jay and Bragazzi, Maria Consiglia and Brooks, Denise and Cardinale, Vincenzo and Carlsen, Rebecca and Carpino, Guido and Carvalho, Andre L and Chaiteerakij, Roongruedee and Chandan, Vishal C and Cherniack, Andrew D and Chin, Lynda and Cho, Juok and Choe, Gina and Chuah, Eric and Chudamani, Sudha and Cibulskis, Carrie and Cordes, Matthew G and Crain, Daniel and Curley, Erin and De Rose, Agostino Maria and Defreitas, Timothy and Demchok, John A and Deshpande, Vikram and Dhalla, Noreen and Ding, Li and Evason, Kimberley and Felau, Ina and Ferguson, Martin L and Foo, Wai Chin and Franchitto, Antonio and Frazer, Scott and Fronick, Catrina C and Fulton, Lucinda A and Fulton, Robert S and Gabriel, Stacey B and Gardner, Johanna and Gastier-Foster, Julie M and Gaudio, Eugenio and Gehlenborg, Nils and Genovese, Giannicola and Gerken, Mark and Getz, Gad and Giama, Nasra H and Gibbs, Richard A and Giuliante, Felice and Grazi, Gian Luca and Hayes, D. Neil and Heiman, David I and Holbrook, Andrea and Holt, Robert A and Hoyle, Alan P and Huang, Mei and Hutter, Carolyn M and Jefferys, Stuart R and Jones, Corbin D and ... and Canc Genome Atlas Network
Cell Reports, ISSN 2211-1247, 03/2017, Volume 18, Issue 11, pp. 2780 - 2794
Cholangiocarcinoma (CCA) is an aggressive malignancy of the bile ducts, with poor prognosis and limited treatment options. Here, we describe the integrated... 
RNA sequencing | lncRNAs | integrative genomics | whole exome | multi-omics | DNA methylation | IDH | ARID1A | cholangiocarcinoma | TCGA | ISOCITRATE DEHYDROGENASE 1 | LIVER-CANCER | HETEROGENEITY | PATHOGENESIS | BILIARY-TRACT CANCER | INTRAHEPATIC CHOLANGIOCARCINOMA | HEPATOCYTES | METABOLISM | THERAPEUTIC TARGETS | MUTATIONS | CELL BIOLOGY | Index Medicus
Journal Article
by Knijnenburg, Theo and Knijnenburg, Theo A and Wang, Chen and Wang, Linghua and Wang, Jing and Wang, Jioajiao and Wang, Min and Wang, Zhining and Wang, Timothy and Zimmermann, Michael T and Chambwe, Nyasha and Gao, Jianjiong and Gao, Galen F and Cherniack, Andrew D and Fan, Huihui and Fan, Cheng and Shen, Yang and Shen, Hui and Way, Gregory P and Greene, Casey S and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Akbani, Rehan and Feng, Bin and Donehower, Lawrence A and Miller, Christopher A and Miller, Chase and Miller, Judy and Miller, Michael and Karimi, Mostafa and Chen, Haoran and Chen, Amy and Chen, Chu and Kim, Jaegil and Kim, Pora and Jia, Peilin and Shinbrot, Eve and Zhang, Hongxin and Zhang, Wei and Zhang, Hailei and Zhang, Jiashan (Julia) and Zhang, Lizhi and Zhang, Jiexin and Zhang, Shaojun and Zhang, Hongzheng and Hu, Jianhong and Hu, Hai and Bailey, Matthew H and Bailey, Matthew and Yau, Christina and Wolf, Denise and Wolf, Gregory and Zhao, Fengmei and Zhao, Zhongming and Weinstein, John N and Li, Lei and Li, Jun and Li, Wei and Ding, Li and Mills, Gordon B and Laird, Peter W and Wheeler, David A and Shmulevich, Ilya and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Ian and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Zenklusen, Jean C and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 239 - 254.e6
Journal Article