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Biophysical Journal, ISSN 0006-3495, 02/2019, Volume 116, Issue 3, p. 49
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2017, Volume 112, Issue 3, pp. 193a - 193a
Journal Article
by Dennis, Martin and Cranswick, G and Deary, A and Fraser, A and Graham, C and Grant, S and Gunkel, A and Hunter, J and MacRae, A and Perry, D and Soosay, V and Williams, C and Williamson, A and Young, A and Dennis, M and Sandercock, P.A.G and Reid, J and Graham, C and Murray, G and Venables, G and Rudd, A and Bowler, G and Cranswick, G and Dennis, M and Graham, C and Lewis, S and Murray, G and Reid, J and Rudd, A and Sandercock, P.A.G and Venables, G and Bowler, G and Celani, M.G and Ricci, S and Lindley, R and Celani, M.G and Hautvast, M and Paterson, M and Reid, J and Ting, T and Baigent, C and Bamford, J and Slattery, J and Beydoun, N and Lindley, R and Romerosa, M and Royan, A and Russell, M and Boers, P and Millar, R and Claxton, A and Hankey, G and Gubitz, G and Jarrett, J and Legg, K and MacKay, M and Nearing, S and Phillips, S and Ehler, E and Geier, P and Mrklovský, M and Anandan, A.M and Kusumakar, G and Rosario, J and Roy, A.K and Duff, C and Farrelly, E and Jadrnickova, M and Masterson, L and Morris, J and Crowe, M and Noone, I and Fancello, M.A and Parish, L.D and Pileri, P and Pinna, M and Piras, M.P and Pirisi, A and Scodino, C and Zedde, M.L and Bondo, V and Capecchi, D and Celani, M.G and Cupella, S and Guerra, L and Macchitella, A and Ottaviani, C and Righetti, E and Rossi, C and Scucchi, M.G and Stefanini, V and Tufi, A and Barilaro, A and Cenciarelli, S and Dioguardi, S and Gallinella, E and Greco, L and Mattioni, A and Mazzoli, T and Ricci, S and ... and The CLOTS Trials Collaboration and CLOTS Trials Collaboration
Lancet, The, ISSN 0140-6736, 2009, Volume 373, Issue 9679, pp. 1958 - 1965
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2018, Volume 114, Issue 3, pp. 408a - 408a
Journal Article
Journal of Inorganic Biochemistry, ISSN 0162-0134, 06/2018, Volume 183, pp. 146 - 156
Structural studies of yeast iso-1-cytochrome c (L.J. McClelland, T.-C. Mou, M.E. Jeakins-Cooley, S.R. Sprang, B.E. Bowler, Proc. Natl. Acad. Sci. U.S.A. 111... 
Cytochrome c | Alkaline conformational transition | Peroxidase activity | Acid unfolding | Apoptosis | Oxidation-Reduction | Cytochromes c - metabolism | Humans | Peroxidases - metabolism | Protein Conformation | Hydrogen-Ion Concentration
Journal Article
Journal of Inorganic Biochemistry, ISSN 0162-0134, 06/2018, Volume 183, p. 146
Structural studies of yeast iso-1-cytochrome c (L.J. McClelland, T.-C. Mou, M.E. Jeakins-Cooley, S.R. Sprang, B.E. Bowler, Proc. Natl. Acad. Sci. U.S.A. 111... 
Cytochrome c | Isomerization | Heme | Peroxidase
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2018, Volume 114, Issue 3, pp. 615a - 615a
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2014, Volume 111, Issue 18, pp. 6648 - 6653
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2018, Volume 114, Issue 2, p. 311
Changing the helical propensity of a polypeptide sequence might be expected to affect the conformational properties of the denatured state of a protein. To... 
Cytochrome | Polypeptides | Rate constants | Stability | Serine | Guanidine | Amino acids | Proteins | Cytochrome c | Properties (attributes) | Histidine | Protein folding | Breakage | Heme | Guanidine hydrochloride | Scaling | Gram-negative bacteria | Mutation | Destabilization
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2017, Volume 112, Issue 3, pp. 387a - 387a
Journal Article
by Kachroo, Priyadarshini and Hecker, Julian and Chawes, Bo L and Ahluwalia, Tarunveer S and Cho, Michael H and Qiao, Dandi and Kelly, Rachel S and Chu, Su H and Virkud, Yamini V and Huang, Mengna and Barnes, Kathleen C and Burchard, Esteban G and Eng, Celeste and Hu, Donglei and Celedón, Juan C and Daya, Michelle and Levin, Albert M and Gui, Hongsheng and Williams, L. Keoki and Forno, Erick and Mak, Angel C.Y and Avila, Lydiana and Soto-Quiros, Manuel E and Cloutier, Michelle M and Acosta-Pérez, Edna and Canino, Glorisa and Bønnelykke, Klaus and Bisgaard, Hans and Raby, Benjamin A and Lange, Christoph and Weiss, Scott T and Lasky-Su, Jessica A and Abe, Namiko and Abecasis, Goncalo and Albert, Christine and Palmer Allred, Nicholette (Nichole) and Almasy, Laura and Alonso, Alvaro and Ament, Seth and Anderson, Peter and Anugu, Pramod and Applebaum-Bowden, Deborah and Arking, Dan and Arnett, Donna K and Ashley-Koch, Allison and Aslibekyan, Stella and Assimes, Tim and Auer, Paul and Avramopoulos, Dimitrios and Barnard, John and Barnes, Kathleen and Barr, R. Graham and Barron-Casella, Emily and Beaty, Terri and Becker, Diane and Becker, Lewis and Beer, Rebecca and Begum, Ferdouse and Beitelshees, Amber and Benjamin, Emelia and Bezerra, Marcos and Bielak, Larry and Bis, Joshua and Blackwell, Thomas and Blangero, John and Boerwinkle, Eric and Borecki, Ingrid and Bowler, Russell and Brody, Jennifer and Broeckel, Ulrich and Broome, Jai and Bunting, Karen and Burchard, Esteban and Cardwell, Jonathan and Carty, Cara and Casaburi, Richard and Casella, James and Chaffin, Mark and Chang, Christy and Chasman, Daniel and Chavan, Sameer and Chen, Bo-Juen and Chen, Wei-Min and Chen, Yii-Der Ida and Cho, Michael H and Choi, Seung Hoan and Chuang, Lee-Ming and Chung, Mina and Cornell, Elaine and Correa, Adolfo and Crandall, Carolyn and Crapo, James and Cupples, L. Adrienne and Curran, Joanne and Curtis, Jeffrey and Custer, Brian and Damcott, Coleen and Darbar, Dawood and Das, Sayantan and David, Sean and ... and National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium and Natl Heart Lung Blood Inst
Chest, ISSN 0012-3692, 12/2019, Volume 156, Issue 6, pp. 1068 - 1079
Asthma is a common respiratory disorder with a highly heterogeneous nature that remains poorly understood. The objective was to use whole genome sequencing... 
whole genome sequencing | airway hyperresponsiveness | asthma | lung function | TESTS | DESIGN | LGL1 | RATIONALE | GUIDELINES | ENDOTYPES | LARGE-SCALE | CHILDHOOD ASTHMA | RESPIRATORY SYSTEM | ASSOCIATION | MAP | CRITICAL CARE MEDICINE
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2019, Volume 116, Issue 3, pp. 371a - 371a
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2015, Volume 108, Issue 2, pp. 213a - 213a
Journal Article
JOURNAL OF PHYSICAL CHEMISTRY B, ISSN 1520-6106, 10/2019, Volume 123, Issue 42, pp. 8939 - 8953
The A51V variant of human cytochrome c is linked to thrombocytopenia 4 (THC4), a condition that causes decreased blood platelet counts. A 1.82 angstrom... 
PROTEIN DYNAMICS | OMEGA-LOOP | ALKALINE CONFORMATIONAL TRANSITION | YEAST ISO-1-CYTOCHROME C | GATED ELECTRON-TRANSFER | UNFOLDING PATHWAY | MUTATION | CHEMISTRY, PHYSICAL | HYDROGEN-PEROXIDE | FERRICYTOCHROME-C | APOPTOTIC ACTIVITY
Journal Article
Biochemistry, ISSN 0006-2960, 05/2016, Volume 55, Issue 19, pp. 2681 - 2693
Journal Article
by Natarajan, Pradeep and Peloso, Gina M and Zekavat, Seyedeh Maryam and Montasser, May and Ganna, Andrea and Chaffin, Mark and Khera, Amit V and Zhou, Wei and Bloom, Jonathan M and Engreitz, Jesse M and Ernst, Jason and O’Connell, Jeffrey R and Ruotsalainen, Sanni E and Alver, Maris and Manichaikul, Ani and Johnson, W. Craig and Perry, James A and Poterba, Timothy and Seed, Cotton and Surakka, Ida L and Esko, Tonu and Ripatti, Samuli and Salomaa, Veikko and Correa, Adolfo and Vasan, Ramachandran S and Kellis, Manolis and Neale, Benjamin M and Lander, Eric S and Abecasis, Goncalo and Mitchell, Braxton and Rich, Stephen S and Wilson, James G and Cupples, L. Adrienne and Rotter, Jerome I and Willer, Cristen J and Kathiresan, Sekar and Abe, Namiko and Albert, Christine and Allred, Nicholette (Nichole) Palmer and Almasy, Laura and Alonso, Alvaro and Ament, Seth and Anderson, Peter and Anugu, Pramod and Applebaum-Bowden, Deborah and Arking, Dan and Arnett, Donna K and Ashley-Koch, Allison and Aslibekyan, Stella and Assimes, Tim and Auer, Paul and Avramopoulos, Dimitrios and Barnard, John and Barnes, Kathleen and Barr, R. Graham and Barron-Casella, Emily and Beaty, Terri and Becker, Diane and Becker, Lewis and Beer, Rebecca and Begum, Ferdouse and Beitelshees, Amber and Benjamin, Emelia and Bezerra, Marcos and Bielak, Larry and Bis, Joshua and Blackwell, Thomas and Blangero, John and Boerwinkle, Eric and Borecki, Ingrid and Bowler, Russell and Brody, Jennifer and Broeckel, Ulrich and Broome, Jai and Bunting, Karen and Burchard, Esteban and Cardwell, Jonathan and Carty, Cara and Casaburi, Richard and Casella, James and Chang, Christy and Chasman, Daniel and Chavan, Sameer and Chen, Bo-Juen and Chen, Wei-Min and Chen, Yii-Der Ida and Cho, Michael and Choi, Seung Hoan and Chuang, Lee-Ming and Chung, Mina and Cornell, Elaine and Crandall, Carolyn and Crapo, James and Curran, Joanne and Curtis, Jeffrey and Custer, Brian and Damcott, Coleen and Darbar, Dawood and Das, Sayantan and David, Sean and ... and NHLBI TOPMed Lipids Working Grp and NHLBI TOPMed Lipids Working Group
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3391 - 12
Large-scale deep-coverage whole-genome sequencing (WGS) is now feasible and offers potential advantages for locus discovery. We perform WGS in 16,324... 
RARE-VARIANT ASSOCIATION | FAMILIAL HYPERCHOLESTEROLEMIA | GENERAL-POPULATION | LOW-FREQUENCY | MULTIDISCIPLINARY SCIENCES | DIVERSE POPULATIONS | POLYGENIC RISK SCORES | GENETIC-VARIANTS | WIDE ASSOCIATION | EFFICIENT | PREDICTION | Cholesterol, LDL - genetics | Gene Frequency - genetics | Genome-Wide Association Study |