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1. Full Text Patterns of c-reactive protein RATIO response in severe community-acquired pneumonia: A cohort study
by Coelho, Luís M and Salluh, Jorge I.F and Soares, Márcio and Bozza, Fernando A and Verdeal, Juan Carlos R and Castro-Faria-Neto, Hugo C and Lapa e Silva, José R and Bozza, Patrícia T and Póvoa, Pedro
Critical Care, ISSN 1364-8535, 03/2012, Volume 16, Issue 2, pp. R53 - R53
Introduction: Community-acquired pneumonia (CAP) requiring intensive care unit (ICU) admission remains a severe medical condition, presenting ICU mortality... 
MANAGEMENT | PREDICTOR | THERAPY | VENTILATOR-ASSOCIATED PNEUMONIA | RESOLUTION | DISEASE | ADULTS | INFECTION | ORGAN FAILURE | SEPSIS | CRITICAL CARE MEDICINE | Biomarkers - metabolism | Prospective Studies | Humans | Middle Aged | Male | Survival Rate | Treatment Outcome | Pneumonia - microbiology | Chi-Square Distribution | Anti-Bacterial Agents - therapeutic use | C-Reactive Protein - metabolism | Pneumonia - drug therapy | Community-Acquired Infections - drug therapy | Statistics, Nonparametric | Aged, 80 and over | Female | ROC Curve | Aged | Community-Acquired Infections - microbiology | APACHE | Cohort Studies | Usage | Pneumonia | C-reactive protein | Prognosis | Antibiotics | Analysis | Bacterial pneumonia | Research | Drug therapy
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2. Full Text Zika virus evolution and spread in the Americas
by Metsky, Hayden C and Matranga, Christian B and Wohl, Shirlee and Schaffner, Stephen F and Freije, Catherine A and Winnicki, Sarah M and West, Kendra and Qu, James and Baniecki, Mary Lynn and Gladden-Young, Adrianne and Lin, Aaron E and Tomkins-Tinch, Christopher H and Ye, Simon H and Park, Daniel J and Luo, Cynthia Y and Barnes, Kayla G and Shah, Rickey R and Chak, Bridget and Barbosa-Lima, Giselle and Delatorre, Edson and Vieira, Yasmine R and Paul, Lauren M and Tan, Amanda L and Barcellona, Carolyn M and Porcelli, Mario C and Vasquez, Chalmers and Cannons, Andrew C and Cone, Marshall R and Hogan, Kelly N and Kopp, Edgar W and Anzinger, Joshua J and Garcia, Kimberly F and Parham, Leda A and Ramírez, Rosa M. Gélvez and Montoya, Maria C. Miranda and Rojas, Diana P and Brown, Catherine M and Hennigan, Scott and Sabina, Brandon and Scotland, Sarah and Gangavarapu, Karthik and Grubaugh, Nathan D and Oliveira, Glenn and Robles-Sikisaka, Refugio and Rambaut, Andrew and Gehrke, Lee and Smole, Sandra and Halloran, M. Elizabeth and Villar, Luis and Mattar, Salim and Lorenzana, Ivette and Cerbino-Neto, Jose and Valim, Clarissa and Degrave, Wim and Bozza, Patricia T and Gnirke, Andreas and Andersen, Kristian G and Isern, Sharon and Michael, Scott F and Bozza, Fernando A and Souza, Thiago M.L and Bosch, Irene and Yozwiak, Nathan L and Macinnis, Bronwyn L and Sabeti, Pardis C
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7658, pp. 411 - 415
Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects have attracted a great deal of attention(1,2), much remains... 
TRANSMISSION | MODELS | EBOLA | PERFORMANCE | MULTIDISCIPLINARY SCIENCES | ACCURACY | United States - epidemiology | Zika Virus - genetics | Genome, Viral - genetics | Humans | Geographic Mapping | Disease Outbreaks - statistics & numerical data | Phylogeny | Culicidae - virology | Zika Virus Infection - virology | Metagenome - genetics | Public Health Surveillance | Puerto Rico - epidemiology | Brazil - epidemiology | Zika Virus - pathogenicity | Zika Virus - classification | Colombia - epidemiology | Zika Virus - isolation & purification | Honduras - epidemiology | Mosquito Vectors - virology | Zika Virus Infection - transmission | Animals | Zika Virus Infection - diagnosis | Zika Virus Infection - epidemiology | Molecular Epidemiology | Mutation | Epidemics | Congenital defects | Pathogenesis | Viruses | Outbreaks | Zika virus | Genomes | Multivariate analysis | Aquatic insects | Epidemiology | Gene sequencing | Phylogenetics | Evolution | Bioinformatics | Urine | Vector-borne diseases | Dengue fever | Birth defects | Genetic diversity | Mosquitoes | Surveillance | Software | Diagnostic systems | Circulation | Viral infections
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3. Full Text OGLE-2018-BLG-1011Lb,c: Microlensing Planetary System with Two Giant Planets Orbiting a Low-mass Star
by Han, C and Bennett, DP and Udalski, A and Gould, A and Bond, IA and Shvartzvald, Y and Nikolaus, KS and Hundertmark, M and Bozza, V and Cassan, A and Hirao, Y and Bachelet, E and Fouque, P and Albrow, MD and Chung, SJ and Hong, K and Hwang, KH and Lee, CU and Ryu, YH and Shin, IG and Yee, JC and Jung, YK and Cha, SM and Kim, D and Kim, DJ and Kim, HW and Kim, SL and Lee, DJ and Lee, Y and Park, BG and Pogge, RW and Mroz, P and Szymanski, MK and Skowron, J and Poleski, R and Soszynski, I and Pietrukowicz, P and Kozlowski, S and Ulaczyk, K and Rybicki, KA and Iwanek, P and Wrona, M and Abe, F and Barry, R and Bhattacharya, A and Donachie, M and Fukui, A and Itow, Y and Kawasaki, K and Kondo, I and Koshimoto, N and Li, MCA and Matsubara, Y and Muraki, Y and Miyazaki, S and Nagakane, M and Ranc, C and Rattenbury, NJ and Suematsu, H and Sullivan, DJ and Sumi, T and Suzuki, D and Tristram, PJ and Yonehara, A and Mao, SD and Wang, TS and Zang, WC and Zhu, W and Penny, MT and Beichman, CA and Bryden, G and Novati, SC and Gaudi, BS and Henderson, CB and Jacklin, S and Stassun, KG and MOA Collaboration and OGLE Collaboration and KMTNet Collaboration and CFHT Collaboration and UKIRT Microlensing Team and The OGLE Collaboration and Leading Authors and The CFHT Collaboration and The UKIRT Microlensing Team and The MOA Collaboration and The KMTNet Collaboration
ASTRONOMICAL JOURNAL, ISSN 0004-6256, 09/2019, Volume 158, Issue 3, p. 114
We report a multiplanetary system found from the analysis of microlensing event OGLE-2018-BLG-1011, for which the light curve exhibits a double-bump anomaly... 
gravitational lensing: micro | MIGRATION | ROTATION | planetary systems | EVENTS | BINARY-SOURCE | PHOTOMETRY | ASTRONOMY & ASTROPHYSICS | JUPITER/SATURN ANALOG | LENS | DISCOVERY
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4. Full Text Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4′-di-O-methylisoscutellarein
by Teles, Yanna C. F and Ribeiro-Filho, Jaime and Bozza, Patrícia T and Agra, Maria de Fátima and Siheri, Weam and Igoli, John O and Gray, Alexander I and Souza, Maria de Fátima V. de
Natural Product Research, ISSN 1478-6419, 08/2016, Volume 30, Issue 16, pp. 1880 - 1884
This study reports the first phenolics from Wissadula genus (Malvaceae) and the anti-inflammatory activity of 7,4′-di-O-methylisoscutellarein. Using... 
Malvaceae | Wissadula periplocifolia | 7,4′-di-O-methylisoscutellarein | anti-inflammatory activity | 7,4 '-di-O-methylisoscutellarein | CHEMISTRY, MEDICINAL | ANTIOXIDANT | CHEMISTRY, APPLIED | Tumor Necrosis Factor-alpha - metabolism | Drug Evaluation, Preclinical - methods | Flavones | Plant Components, Aerial - chemistry | Mice, Inbred C57BL | Neutrophils - drug effects | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Pleurisy - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Hydroxybenzoates - pharmacology | Animals | Parabens - pharmacology | Pleurisy - drug therapy | Phenols - chemistry | Malvaceae - chemistry | Molecular Structure | Disease Models, Animal | Neutrophils - pathology | Phenols - pharmacology
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5. Full Text Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response
by Vecchi, Annunciata and Mantovani, Alberto and Vago, Luca and De Santis, Rita and Altruda, Fiorella and Romani, Luigina and Bottazzi, Barbara and Garlanda, Cecilia and Hirsch, Emilio and Carminati, Paolo and Bozza, Silvia and Nota, Rachele and Doni, Andrea and Siracusa, Gregorio and De Acetis, Marika and Maccagno, Alessia and Peri, Giuseppe and Riva, Federica and Botto, Marina and Salustri, Antonietta
Nature, ISSN 0028-0836, 11/2002, Volume 420, Issue 6912, pp. 182 - 186
Pentraxins are a superfamily of conserved proteins that are characterized by a cyclic multimeric structure. The classical short pentraxins, C-reactive protein... 
C-REACTIVE PROTEIN | AMYLOID-P COMPONENT | INVASIVE ASPERGILLOSIS | A-PROTEIN | ACUTE-PHASE PROTEINS | MONONUCLEAR | MULTIDISCIPLINARY SCIENCES | INFECTION | EXPRESSION | FAMILY | MEMBER | Lung - microbiology | Brain - microbiology | Cytokines - analysis | Dendritic Cells - immunology | Humans | Antifungal Agents - chemistry | Th2 Cells - immunology | Aspergillosis - pathology | C-Reactive Protein - metabolism | Recombination, Genetic | Gene Deletion | Antifungal Agents - metabolism | C-Reactive Protein - deficiency | Aspergillus fumigatus - metabolism | Macrophages, Alveolar - immunology | Cytokines - immunology | Macrophages, Alveolar - microbiology | Disease Susceptibility | Aspergillosis - genetics | Cells, Cultured | Serum Amyloid P-Component - chemistry | Survival Rate | C-Reactive Protein - genetics | C-Reactive Protein - chemistry | Immunity, Innate | Mice, Knockout | Serum Amyloid P-Component - genetics | Animals | Serum Amyloid P-Component - deficiency | Aspergillosis - microbiology | Aspergillus fumigatus - growth & development | Mice | Serum Amyloid P-Component - metabolism | Lung - immunology | Phagocytosis | Fungi | Proteins | Immune system
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6. Full Text The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps
by Jaillon, Sébastien and Peri, Giuseppe and Delneste, Yves and Frémaux, Isabelle and Doni, Andrea and Moalli, Federica and Garlanda, Cecilia and Romani, Luigina and Gascan, Hugues and Bellocchio, Silvia and Bozza, Silvia and Cassatella, Marco A and Jeannin, Pascale and Mantovani, Alberto
Journal of Experimental Medicine, ISSN 0022-1007, 04/2007, Volume 204, Issue 4, pp. 793 - 804
The long pentraxin ( PTX) 3 is produced by macrophages and myeloid dendritic cells in response to Toll-like receptor agonists and represents a nonredundant... 
C-REACTIVE PROTEIN | MEDICINE, RESEARCH & EXPERIMENTAL | AMYLOID-P COMPONENT | ACUTE-PHASE PROTEINS | DENDRITIC CELLS | ACUTE MYOCARDIAL-INFARCTION | INNATE IMMUNE-RESPONSE | TOLL-LIKE RECEPTORS | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | NF-KAPPA-B | LONG PENTRAXIN PTX3 | Neutrophils - cytology | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | C-Reactive Protein - genetics | Mice, Knockout | Serum Amyloid P-Component - genetics | Extracellular Space - metabolism | Animals | C-Reactive Protein - metabolism | Serum Amyloid P-Component - deficiency | Cytoplasmic Granules - metabolism | C-Reactive Protein - deficiency | Protein Binding | Mice | Serum Amyloid P-Component - metabolism | Neutrophils - metabolism
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7. Full Text IP219. Propensity-Matched Cohorts Comparison of Endovascular Versus Open Reconstruction of TransAtlantic Inter-Society Consensus C and D Aortoiliac Occlusive Disease
by Lepidi, Sandro and Squizzato, Francesco and Bozza, Riccardo and Ventura, Laura and Piazza, Michele and Porcellato, Luca and Antonello, Michele and Grego, Franco
Journal of Vascular Surgery, ISSN 0741-5214, 06/2019, Volume 69, Issue 6, pp. e168 - e169
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8. Full Text Toll-Like Receptor-2-Mediated C-C Chemokine Receptor 3 and Eotaxin-Driven Eosinophil Influx Induced by Mycobacterium bovis BCG Pleurisy
by Heloisa D'Ávila and Patrícia E. Almeida and Natália R. Roque and Hugo C. Castro-Faria-Neto and Patrícia T. Bozza
Infection and Immunity, ISSN 0019-9567, 03/2007, Volume 75, Issue 3, pp. 1507 - 1511
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
RESPONSES | INFECTIOUS DISEASES | BACILLUS-CALMETTE-GUERIN | TUBERCULOSIS | MACROPHAGES | IN-VIVO | GRANULOCYTES | LIPOPOLYSACCHARIDE | LIPID BODIES | ACCUMULATION | IMMUNOLOGY | INNATE IMMUNITY | Eosinophils - metabolism | Mycobacterium bovis - immunology | Toll-Like Receptor 2 - genetics | Mice, Inbred C57BL | Chemokine CCL11 | Tuberculosis, Pleural - veterinary | Eosinophils - immunology | Chemotactic Factors, Eosinophil - physiology | Mice, Knockout | Toll-Like Receptor 2 - deficiency | Animals | Receptors, Chemokine - physiology | Chemokines, CC - physiology | Toll-Like Receptor 2 - physiology | Tuberculosis, Pleural - metabolism | Mice | Receptors, CCR3 | Chemotaxis, Leukocyte - immunology | Eosinophils - cytology | Tuberculosis, Pleural - immunology | Host Response and Inflammation
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9. Full Text The epidemiology of sepsis in Brazilian intensive care units (the Sepsis PREvalence Assessment Database, SPREAD): an observational study
by Machado, E C and Machado, D and Machado, F R and Machado, Flavia R and Machado, R S and Cavalcanti, Alexandre Biasi and Bozza, Fernando Augusto and Ferreira, R and Ferreira, I and Ferreira, P and Ferreira, E L A and Ferreira, C S and Ferreira, Elaine M and Angotti Carrara, Fernanda Sousa and Sousa, Juliana Lubarino and Sousa, R K and Caixeta, Noemi and Salomao, Reinaldo and Angus, Derek C and Pontes Azevedo, Luciano Cesar and Zajac, S R and Bley, M V and Scazufca, A and Rosateli, P and Reis, T and Junior, H A O and Junior, J M M and Junior, A D F and Junior, S M D and Junior, A Nogueira and Junior, E A and Neto, P A Nunes and Neto, E Eberhart and Neto, M L and Neto, J S A and Filho, W H and Filho, C M F and Filho, E Thomé and Filho, J Mugait and Filho, I L S and Filho, G T Henriques and Filho, H Carvalho and Filho, M C and Filho, W O and Lima, G S and Lima, R and Lima, M F A and Lima, M A M and Lima, H and Vieira, M and Vieira, S and Vieira, P C B and Vieira, E and Zanchet, M and Miguita, R and Petisco, G M and Westphal, G A and Santos, J R P and Santos, J C and Santos, V and Santos, L and Santos, A P G and Damasceno, M and Damasceno, V and dos Santos, J T and dos Santos, R Perreira and Fernandes, F and Fernandes, L and Fernandes, R and Fernandes, S S and Almeida, E P and Almeida, R and Almeida, EP and Lemos, M and Camacho, R and Ribeiro, A G and Ribeiro, A and Douglas, M O G and Mattei, G A and Rabelo, H R M P and Pinto, V G S and Pinto, E M and Pinto, S P S and Fontes, L E and Guitzel, M and Lucio, M and Conceição, C N P and Barros, A and Salgado, D and Veiga, V C and Rojas, S S O and de Paula, KM and Hatum, R and Fraenkel, L and Viana, W N and Rabello, L and Tanaka, L and Uchoa, M and Moura, M D and Moura, E M F and ... and Latin American Sepsis Institute Ne and SPREAD Investigators and Latin American Sepsis Institute Network
The Lancet Infectious Diseases, ISSN 1473-3099, 11/2017, Volume 17, Issue 11, pp. 1180 - 1189
The sepsis burden on acute care services in middle-income countries is a cause for concern. We estimated incidence, prevalence, and mortality of sepsis in... 
MORTALITY | INFECTIOUS DISEASES | MULTICENTER | AMERICA | COUNTRY | GUIDELINES | SEPTIC SHOCK | CRITICALLY-ILL | Length of Stay | Intensive Care Units | Prevalence | Humans | Risk Factors | Sepsis - epidemiology | Survival Analysis | Random Allocation | Brazil - epidemiology | Incidence | Sepsis - mortality | Epidemiology | Questions and answers | Databases | Analysis | Studies | Intensive care units | Economic models | Intensive care | Hospitals | Mortality | Sepsis
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10. Full Text IP181. Early and Long-Term Outcomes of Open Versus Endovascular Repair Using Covered Stents for TASC C-D Aortoiliac Obstructive Lesions in Low-Risk and Young Patients
by Piazza, Michele and Squizzato, Francesco and Bozza, Riccardo and Lepidi, Sandro and Menegolo, Mirko and Grego, Franco and Antonello, Michele
Journal of Vascular Surgery, ISSN 0741-5214, 06/2018, Volume 67, Issue 6, pp. e135 - e136
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11. Full Text Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo
by de Freitas, Caroline S and Higa, Luiza M and Sacramento, Carolina Q and Ferreira, André C and Reis, Patrícia A and Delvecchio, Rodrigo and Monteiro, Fabio L and Barbosa-Lima, Giselle and James Westgarth, Harrison and Vieira, Yasmine Rangel and Mattos, Mayara and Rocha, Natasha and Hoelz, Lucas Villas Bôas and Leme, Rennan Papaleo Paes and Bastos, Mônica M and L Rodrigues, Gisele Olinto and M Lopes, Carla Elizabeth and Queiroz-Junior, Celso Martins and Lima, Cristiano X and Costa, Vivian V and Teixeira, Mauro M and Bozza, Fernando A and Bozza, Patrícia T and Boechat, Nubia and Tanuri, Amilcar and Souza, Thiago Moreno L
PLoS neglected tropical diseases, ISSN 1935-2735, 01/2019, Volume 13, Issue 1, p. e0007072
Yellow fever virus (YFV) is a member of the Flaviviridae family. In Brazil, yellow fever (YF) cases have increased dramatically in sylvatic areas neighboring... 
DENGUE | INTERFERON | REPLICATION | MODELS | POLYMERASE | RIBAVIRIN | ZIKA VIRUS | PARASITOLOGY | TROPICAL MEDICINE | Surveys | Drug approval | Health aspects | Urban health | Analysis | Yellow fever | Drugs | Neonates | Transplants & implants | RNA | Liver | Viral diseases | Amino acids | Outbreaks | Viruses | Zika virus | Lethality | Nucleotides | Hepatoma | Vaccines | DNA-directed RNA polymerase | Epidemiology | Hepatitis | Receptors | Public health | Vector-borne diseases | Antiviral agents | Economic models | Human diseases | Research & development--R&D | Dengue | Weight loss | Nucleic acids | Disease control | Fever | Polymerase | Docks | Infectious diseases | Strains | Morphology | Interferon | Mice | Hepatitis C virus | Hepatitis C | Pharmaceuticals | Research & development | R&D
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12. Full Text Letter of intent for KM3NeT 2.0
by Aian-Martinez, S and Ageron, M and Aharonian, F and Aiello, S and Albert, A and Ameli, F and Anassontzis, E and Ane, M and Anoulakis, G and Anghinolfi, M and Anton, G and Ardid, M and Avgitas, T and Barbarino, G and Barbarito, E and Baret, B and Barrios-Marti, J and Belhorma, B and Belias, A and Berbee, E and van den Berg, A and Bertin, V and Beurthey, S and van Beveren, V and Beverini, N and Biagi, S and Biagioni, A and Billault, M and Bondi, M and Bormuth, R and Bouhadef, B and Bourlis, G and Bourret, S and Boutonnet, C and Bouwhuis, M and Bozza, C and Bruijn, R and Brunner, J and Buis, E and Dorosti-Hasankiadeh, Q and kopoulou, E and Graf, K and Hevinga, M and de Jong, M and Koffeman, E. N and Martini, A and Melis, K. W and Timmer, P and Wiggers, L and Wilms, J and Löhner, H
Journal of Physics. G: Nuclear and Particle Physics, ISSN 0954-3899, 08/2016, Volume 43, Issue 8, p. 84001
The main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the... 
neutrino physics | neutrino astronomy | PARAMETRIC-RESONANCE | deep sea neutrino telescope | GAMMA-RAY BURSTS | HIGH-ENERGY NEUTRINOS | neutrino mass hierarchy | MONTE-CARLO GENERATOR | GALACTIC-CENTER | COSMIC-RAYS | SUPER-KAMIOKANDE | ICECUBE DATA | ATMOSPHERIC NEUTRINOS | SEARCH | PHYSICS, NUCLEAR | GAMMA-RAY EMISSION | POINT-LIKE | OSCILLATIONS | PHYSICS, PARTICLES & FIELDS | Física de partícules | Neutrins | Neutrino astrophysics | Àrees temàtiques de la UPC | Física
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