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by Khazaei, Mohamad and Baig, Sara and Merchant, Jainetri and Chan, Priscilla and Fehlings, Michael and Fehlings, Michael and Fehlings, Michael and Giudice, J. Sebastian and Forman, Jason and Panzer, Matthew B and Dalton, Jay and Mauria, Rohit and Chapple, Kristina and Cook, Alan and Turner, Jay and McCrea, Michael A and Nelson, Lindsay D and Tummala, Shanti and Meaney, David and Hawryluk, Gregory and Nielson, Jessica and Huie, J. Russell and Zimmermann, Lara and Saigal, Rajiv and Ding, Quan and Ferguson, Adam and Manley, Geoffrey and Lee, Stephanie and Gajavelli, Shyam and Gajavelli, Shyam and Gajavelli, Shyam and Spurlock, Markus and Spurlock, Markus and Rivera, Karla and Rivera, Karla and Rivera, Karla and Androni, Cody and de Rivero Vaccari, Juan Pablo and de Rivero Vaccari, Juan Pablo and Keane, Robert and Bulock, Ross and Dietrich, Dalton and Meeker, Kole and Bullock, Kristin and Banks, William and Cook, David and Main, Bevan and Villapol, Sonia and Barton, David and Sloley, Stephanie and Stefos, Kathryn and Burns, Mark and Swanson, Randel and Johnson, Victoria and Parker, Andrew and Elliott, Mark and Weber, Maura and Acharya, Nimish and Cognetti, John and Cullen, Kacy and Verma, Ragini and Smith, Douglas and Pat, Betty and Pat, Betty and McAllister, Sean and Floyd, Candace and Floyd, Candace and Harris, Neil G and Reynolds, Joshua and Turtle, Joel and Leal, Gizelle and Huang, Yung-Jen and Strain, Misty and Grau, James and Greco, Tiffany and Giza, Christopher and Prins, Mayumi and Folkerts, Michael and Russo, Robin and Koch, Paul and Koch, Paul and Adam, Christopher and Weber, Maura and Johnson, Victoria and Johnson, Victoria and Wolf, John and Wolf, John and Cai, Yan and Perigo, Shauna and Bhaduri, Srija and Rosenbaum, Philip and Harris, Neil G and Giza, Christopher C and Kumar, Raj and Kumar, Raj and Ranganathan, Prerna and Ranganathan, Prerna and Ranganathan, Prerna and Oh, Byung-Mo and Wagner, Amy and ...
Journal of Neurotrauma, ISSN 0897-7151, 07/2017, Volume 34, Issue 13, pp. A-1 - A-163
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2017, Volume 19, Issue 9, pp. 1017 - 1026
Although normally dormant, hair follicle stem cells (HFSCs) quickly become activated to divide during a new hair cycle. The quiescence of HFSCs is known to be... 
MORPHOGENESIS | MITOCHONDRIAL PYRUVATE CARRIER | METABOLISM | QUIESCENCE | C-MYC | NICHE | SKIN | INDUCTION | EXPRESSION | CYCLE | CELL BIOLOGY | L-Lactate Dehydrogenase - metabolism | Mitochondrial Membrane Transport Proteins - antagonists & inhibitors | Cellular Senescence - drug effects | Male | Glycolysis - drug effects | Mitochondrial Membrane Transport Proteins - genetics | Monocarboxylic Acid Transporters | Anion Transport Proteins - antagonists & inhibitors | Stem Cells - enzymology | Time Factors | Isoenzymes - metabolism | Acrylates - pharmacology | Female | Mitochondrial Membrane Transport Proteins - metabolism | Signal Transduction | Isoenzymes - genetics | Lactic Acid - metabolism | Mice, Inbred C57BL | Genotype | Hair Follicle - enzymology | Isoenzymes - deficiency | Anion Transport Proteins - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Mice, Knockout | Hair Follicle - drug effects | Hair Follicle - cytology | Phenotype | Animals | L-Lactate Dehydrogenase - genetics | L-Lactate Dehydrogenase - deficiency | Stem Cells - drug effects | Cell Proliferation - drug effects | Anion Transport Proteins - genetics | Lactate Dehydrogenase 5 | Cell metabolism | Lactate dehydrogenase | Genetic aspects | Hair follicles | Health aspects | Stem cells | Hair | Dehydrogenases | Pyruvic acid | Epidermis | Activation | Myc protein | Dehydrogenase | Metabolism | L-Lactate dehydrogenase | Mitochondria | Cell activation | Clonal deletion | Glycolysis | Lactic acid
Journal Article
by Tazoe, Toshiki and Huie, J. Russell and Guandique, Cristian F and Ma, Xiaokui and Sacramento, Jeffrey A and Tanaka, Sakae and Bresnahan, Jacqueline C and Beattie, Michael S and Ogata, Toru and Ferguson, Adam R and Ruan, Yiwen and Chen, Chen and Frye, Christian Corbin and Sengelaub, Dale and Xiong, Wenhui and Xiong, Wenhui and Jin, Xiaoming and Xu, Xiao-Ming and Xu, Xiao-Ming and Daphalapurkar, Nitin and Knutsen, Andrew and Pham, Dzung L and Ramesh, K.T and Tallarida, Christopher and Razmpour, Roshanak and Razmpour, Roshanak and Lutton, Evan and Persidsky, Yuri and Rawls, Scott and Ramirez, Servio and Ford, Joni and Burnsides, Chris and Fenn, Ashley and Popovich, Phillip and Lifshitz, Jonathan and Lifshitz, Jonathan and Walker, Rohan and Eiferman, Daniel and Godbout, Jonathan and Tyburski, Ashley and Clark, Shannon and Elliott, Melanie and Wang, Jian and Liu, Yang and Badner, Anna and Dragas, Rachel and Siddiqui, Ahad and Forner, Stefania and Vawda, Reaz and Fehlings, Michael and Hovda, David and Prins, Mayumi and May, Hazel and Rowe, Rachel and Rowe, Rachel and Rumney, Benjamin and Johnson, Steven and Adelson, P. David and Lifshitz, Jonathan and Thomas, Theresa and Nielson, Jessica and Guandique, Cristian and Liu, Aiwen and Tovar, C. Amy and Young, Wise and Beattie, Michael and Bresnahan, Jacqueline and Bresnahan, Jacqueline and Ferguson, Adam and DePasquale, Erica and Dorsett, Christopher and Floyd, Candace L and McCullumsmith, Robert and Tyagi, Reeta and Dale, Jacob and Benton, Richard L and Tyagi, Suresh C and Hoying, James B and Lominadze, David and Browne, Kevin D and Wolf, John A and Smith, Douglas H and Duda, John E and Cullen, D. Kacy and Juengst, Shannon and Failla, Michelle and Failla, Michelle and Galang, Gary and Conley, Yvette and Arenth, Patricia and Arenth, Patricia and Wagner, Amy and Wagner, Amy and Cheng, Jeffrey P and Bondi, Corina O and Kline, Anthony E and Chapman, Sandra and Krawczyk, Daniel and Ellis, Monica and Marion, Sarah and ...
Journal of Neurotrauma, ISSN 0897-7151, 06/2015, Volume 32, Issue 12, pp. A-1 - A-152
Journal Article
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 479 - 483
B-lymphoid transcription factors, such as PAX5 and IKZF1, are critical for early B-cell development(1,2), yet lesions of the genes encoding these transcription... 
ENERGY STRESS | ACTIVATION | GENE | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | HEMATOPOIETIC STEM-CELLS | REGULATORY NETWORK | DIFFERENTIATION | MINIMAL RESIDUAL DISEASE | EXPRESSION | Glucocorticoids - therapeutic use | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Receptor, Cannabinoid, CB2 - agonists | Humans | Gene Expression Regulation, Neoplastic | Receptors, Glucocorticoid - metabolism | PAX5 Transcription Factor - deficiency | Carrier Proteins - agonists | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Chromatin Immunoprecipitation | Adenosine Triphosphate - metabolism | Cell Death | Pyruvic Acid - metabolism | Female | Ikaros Transcription Factor - metabolism | Energy Metabolism - genetics | B-Lymphocytes - metabolism | PAX5 Transcription Factor - metabolism | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | AMP-Activated Protein Kinases - antagonists & inhibitors | Carcinogenesis - genetics | PAX5 Transcription Factor - genetics | Mice, Transgenic | Citric Acid Cycle | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Transcription Factors - metabolism | B-Lymphocytes - drug effects | Receptor, Cannabinoid, CB2 - metabolism | Animals | Carrier Proteins - metabolism | Sequence Analysis, RNA | Glucocorticoids - pharmacology | Glucose - metabolism | Mice | Physiological aspects | Transcription factors | B cells | Proteins | Metabolites | Rodents | Cloning | Leukemia | Glucose | Kinases | Metabolism | Gene expression | Apoptosis
Journal Article
Nature Communications, ISSN 2041-1723, 11/2015, Volume 6, Issue 1, p. 8873
Viruses rewire host cell glucose and glutamine metabolism to meet the bioenergetic and biosynthetic demands of viral propagation. However, the mechanism by... 
PATHWAY | METABOLIC-RESPONSES | GLUCOSE | MULTIDISCIPLINARY SCIENCES | INFECTION | CELL-GROWTH | REDUCTIVE CARBOXYLATION | Cell Line | Humans | Glutamine - metabolism | Adenoviridae - physiology | Proto-Oncogene Proteins c-myc - genetics | Mutation | Proto-Oncogene Proteins c-myc - metabolism | Virus Replication - physiology
Journal Article
CELL DISCOVERY, ISSN 2056-5968, 11/2019, Volume 5, Issue 1, pp. 1 - 10
Metabolic obstacles of the tumor microenvironment remain a challenge to T-cell-mediated cancer immunotherapies. To better understand the interplay of immune... 
SURVIVAL | METABOLOMICS | EXTRACTION | ACTIVATION | PURINE | CELL-PROLIFERATION | INHIBITOR | MAMMALIAN-CELLS | CELL BIOLOGY | Cell proliferation | Tricarboxylic acid cycle | Metabolomics | Memory cells | Succinyl-CoA | PD-1 protein | Pyruvic acid | Mass spectroscopy | Lymphocytes T | Metabolism | Immune checkpoint | Metabolites | PD-L1 protein | Glycolysis | Carboxylation | Nucleosides | Oxidation
Journal Article
Cell, ISSN 0092-8674, 2009, Volume 138, Issue 1, pp. 114 - 128
We describe a broad mechanistic framework for the transcriptional induction of mammalian primary response genes by Toll-like receptors and other stimuli. One... 
MOLIMMUNO | DNA | DNA INTERACTIONS | POLY(DA-DT) | HUMAN GENOME | CHROMATIN | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACCESSIBILITY | PROMOTER | IDENTIFICATION | BAF COMPLEX | HISTONE | CELL BIOLOGY | Nucleosomes | DNA binding proteins | Molecular genetics | Biological response modifiers | Interferon beta
Journal Article