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Molecular Cancer Therapeutics, ISSN 1535-7163, 11/2006, Volume 5, Issue 11, pp. 2606 - 2612
The panel of 60 human cancer cell lines (the NCI-60) assembled by the National Cancer Institute for anticancer drug discovery is a widely used resource. The... 
DNA sequence | mutation | cancer | gene | cell line | NCI-60 | GROWTH-FACTOR RECEPTOR | LUNG-CANCER | PANEL | DNA COPY NUMBER | ONCOLOGY | SENSITIVITY | INHIBITORS | ANTICANCER DRUG SCREEN | EXPRESSION | SOMATIC MUTATIONS | MOLECULAR PHARMACOLOGY | Homozygote | RNA Splice Sites | DNA Mutational Analysis | Exons | Gene Deletion | Genes, Neoplasm | Humans | Cell Line, Tumor | Gene Expression Profiling | Mutation
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2005, Volume 37, Issue 6, pp. 590 - 592
We examined the coding sequence of 518 protein kinases, ∼1.3 Mb of DNA per sample, in 25 breast cancers. In many tumors, we detected no somatic mutations. But... 
SACCHAROMYCES-CEREVISIAE | GENOME | GENETICS & HEREDITY | Carcinoma, Ductal, Breast - genetics | Multigene Family | Protein Kinases - genetics | Breast Neoplasms - genetics | DNA Mutational Analysis | Humans | Female | Aged | Mutation | Gene mutations | Physiological aspects | Breast cancer | Genetic aspects | Research | Health aspects | Protein kinases | Risk factors
Journal Article
by White, Gemma and White, Jacqueline K and Gerdin, Anna-Karin and Karp, Natasha A and Ryder, Ed and Buljan, Marija and Bussell, James N and Salisbury, Jennifer and Clare, Simon and Ingham, Neil J and Podrini, Christine and Houghton, Richard and Estabel, Jeanne and Bottomley, Joanna R and Melvin, David G and Sunter, David and Adams, David J and Adams, Niels C and Baker, Lauren and Barnes, Caroline and Beveridge, Ryan and Cambridge, Emma and Carragher, Damian and Chana, Prabhjoat and Clarke, Kay and Hooks, Yvette and Igosheva, Natalia and Ismail, Ozama and Jackson, Hannah and Kane, Leanne and Lacey, Rosalind and Lafont, David Tino and Lucas, Mark and Maguire, Simon and McGill, Katherine and McIntyre, Rebecca E and Messager, Sophie and Mottram, Lynda and Mulderrig, Lee and Pearson, Laila and Pearson, Selina and Protheroe, Hayley J and Roberson, Laura-Anne and Salsbury, Grace and Sanderson, Mark and Sanger, Daniel and Shannon, Carl and Thompson, Paul C and Tuck, Elizabeth and Vancollie, Valerie E and Brackenbury, Lisa and Bushell, Wendy and Cook, Ross and Dalvi, Priya and Gleeson, Diane and Habib, Bishoy and Hardy, Matt and Liakath-Ali, Kifayathullah and Miklejewska, Evelina and Price, Stacey and Sethi, Debarati and Trenchard, Elizabeth and von Schiller, Dominique and Vyas, Sapna and West, Anthony P and Woodward, John and Wynn, Elizabeth and Evans, Arthur and Gannon, David and Griffiths, Mark and Holroyd, Simon and Iyer, Vivek and Kipp, Christian and Lewis, Morag and Li, Wei and Oakley, Darren and Richardson, David and Smedley, Damian and Agu, Chukwuma and Bryant, Jackie and Delaney, Liz and Gueorguieva, Nadia I and Tharagonnet, Helen and Townsend, Anne J and Biggs, Daniel and Brown, Terry and Brown, Ellen and Collinson, Adam and Dumeau, Charles-Etienne and Grau, Evelyn and Harrison, James and Harrison, Sarah and Ingle, Catherine E and Kundi, Helen and Madich, Alla and Mayhew, Danielle and Metcalf, Tom and Newman, Stuart and Pass, Johanna and Reynolds, Helen and ... and Sanger Inst Mouse Genetics Project and Sanger Institute Mouse Genetics Project
Cell, ISSN 0092-8674, 07/2013, Volume 154, Issue 2, pp. 452 - 464
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 09/2004, Volume 431, Issue 7008, pp. 525 - 526
Journal Article
Nature, ISSN 0028-0836, 09/2004, Volume 431, Issue 7008, pp. 525 - 526
The protein-kinase family is the most frequently mutated gene family found in human cancer and faulty kinase enzymes are being investigated as promising... 
CELL LUNG-CANCER | GEFITINIB | MULTIDISCIPLINARY SCIENCES
Journal Article
Cancer Research, ISSN 0008-5472, 09/2005, Volume 65, Issue 17, pp. 7591 - 7595
Journal Article
Cancer Research, ISSN 0008-5472, 04/2006, Volume 66, Issue 8, pp. 3987 - 3991
Journal Article
2013
There is currently little known about the role of extracellular matrix (ECM) in the regulation of microRNA (miRs), a family of short, non-coding RNA that... 
mammary | microRNA | epithelial
Dissertation
Journal Article
Genes, Chromosomes and Cancer, ISSN 1045-2257, 01/2006, Volume 45, Issue 1, pp. 42 - 46
The protein kinase gene family is the most frequently mutated in human cancer. Previous work has documented activating mutations in the KIT receptor tyrosine... 
ONCOLOGY | CANCER | SOMATIC MUTATIONS | GENOME | KIT | GENETICS & HEREDITY | Protein Kinases - genetics | Testicular Neoplasms - genetics | Exons | Humans | Middle Aged | Protein-Serine-Threonine Kinases - genetics | Male | Gene Dosage | Neoplasms, Germ Cell and Embryonal - genetics | Point Mutation | Adolescent | Chromosome Aberrations | Adult | Seminoma - genetics
Journal Article