X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (27) 27
life sciences (22) 22
cancer (20) 20
animals (17) 17
biochemistry, molecular biology (15) 15
hypoxia (14) 14
mesh : humans (14) 14
neoplasms - metabolism (13) 13
[ sdv.bbm ] life sciences [q-bio]/biochemistry, molecular biology (12) 12
[ sdv.can ] life sciences [q-bio]/cancer (12) 12
cell hypoxia (12) 12
cell biology (10) 10
hypoxia-inducible factor 1, alpha subunit (10) 10
index medicus (10) 10
neoplasms (10) 10
angiogenesis (9) 9
expression (9) 9
hypoxia-inducible factor (9) 9
mesh : animals (9) 9
mesh : hypoxia-inducible factor 1, alpha subunit (9) 9
mesh : neoplasms (9) 9
oxygen (9) 9
hypoxia-inducible factor 1, alpha subunit - metabolism (8) 8
mesh : signal transduction (8) 8
neoplasms - pathology (8) 8
signal transduction (8) 8
development biology (7) 7
hydrogen-ion concentration (7) 7
mesh : cell hypoxia (7) 7
mice (7) 7
oxygen - metabolism (7) 7
[ sdv.bdd ] life sciences [q-bio]/development biology (6) 6
anoxia (6) 6
autophagy (6) 6
biochemistry & molecular biology (6) 6
cell line, tumor (6) 6
oncology (6) 6
proteins (6) 6
cell proliferation (5) 5
cell survival (5) 5
cells (5) 5
glycolysis (5) 5
hypoxia-inducible factor 1 (5) 5
lipase (5) 5
male (5) 5
mesh : anoxia (5) 5
mesh : hypoxia-inducible factor 1 (5) 5
mesh : oxygen (5) 5
mitochondria - metabolism (5) 5
protein processing, post-translational (5) 5
apoptosis (4) 4
carbonic-anhydrase-ix (4) 4
cystic fibrosis transmembrane conductance regulator - genetics (4) 4
esterase (4) 4
glucose - metabolism (4) 4
hela cells (4) 4
hypoxia-inducible factor 1 - metabolism (4) 4
hypoxia-inducible factor 1, alpha subunit - genetics (4) 4
mesh : hydrogen-ion concentration (4) 4
mesh : transcription factors (4) 4
mitochondria (4) 4
models, biological (4) 4
neoplasms - drug therapy (4) 4
oxygen-sensor (4) 4
physiological aspects (4) 4
protein structure, tertiary (4) 4
transcription factors (4) 4
transfection (4) 4
tumors (4) 4
acetyltransferases - metabolism (3) 3
acidification (3) 3
acidosis (3) 3
activation (3) 3
adenocarcinoma - metabolism (3) 3
ard1 (3) 3
biotechnology & applied microbiology (3) 3
carbonic anhydrase (3) 3
cell hypoxia - physiology (3) 3
cell line (3) 3
cystic fibrosis - genetics (3) 3
cystic fibrosis transmembrane conductance regulator (3) 3
cytoplasm (3) 3
cytoplasm - metabolism (3) 3
dynamics (3) 3
factor-1-alpha (3) 3
female (3) 3
gene (3) 3
gene expression (3) 3
gene expression regulation (3) 3
gene-expression (3) 3
genetics & heredity (3) 3
glucose (3) 3
hif hydroxylases (3) 3
hypoxia - metabolism (3) 3
identification (3) 3
medicine, research & experimental (3) 3
mesh : cell line, tumor (3) 3
mesh : cell proliferation (3) 3
mesh : hela cells (3) 3
mesh : models, biological (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 04/2010, Volume 14, Issue 4, pp. 771 - 794
•  Introduction •  Intracellular pH regulation controls energy balance and cell proliferation: chemical and biological proof of principle ‐  Chemical proof of... 
oncogenes activation | Na+/H+ exchanger | monocarboxylate transporters | acidosis | glycolysis | pH homeostasis | carbonic anhydrases | energy production | hypoxia‐inducible factor | tumour microenvironment | Carbonic anhydrases | Monocarboxylate transporters | Oncogenes activation | Glycolysis | Hypoxia-inducible factor | Acidosis | PH homeostasis | Energy production | Tumour microenvironment | MEDICINE, RESEARCH & EXPERIMENTAL | CARBONIC-ANHYDRASE-IX | ACTIVATED PROTEIN-KINASE | INTRACELLULAR PH | hypoxia-inducible factor | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | CA-IX | Na | DEPENDENT CL-HCO3-EXCHANGE | H plus exchanger | GENE-EXPRESSION | NA+/H+ EXCHANGER | EXTRACELLULAR PH | INDUCIBLE-FACTOR | Cell Hypoxia | Neoplasms - metabolism | Neoplasms - complications | Acidosis - complications | Energy Metabolism | Cell Transformation, Neoplastic | Humans | Neoplasms - pathology | Hydrogen-Ion Concentration | Regulations | Transformation | Oxidative metabolism | Acidification | Metastasis | CD147 antigen | pH effects | Drug resistance | Cancer therapies | Metastases | Cell activation | Cell growth | Cooperation | Inhibition | Enzymes | Metabolism | Gene expression | Survival | Membrane proteins | Energy balance | Organic chemistry | Chemotherapy | Protein synthesis | Hypoxia | Oxygen tension | Transporter | Cell migration | Cell proliferation | Phosphorylation | Toxicity | Hydrogen | Gene regulation | Homeostasis | Activation | Cell adhesion & migration | Collapse | Oxygen | Cell survival | Na+/H+-exchanging ATPase | Multidrug resistance | Radiation therapy | Acids | Oxidative phosphorylation | Medical prognosis | Tumor suppressor genes | Intracellular | Tumors | Apoptosis | Index Medicus | Life Sciences | Development Biology | Reviews | H+ exchanger | Na+
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 12/2007, Volume 85, Issue 12, pp. 1301 - 1307
A major feature of solid tumours is hypoxia, decreased availability of oxygen, which increases patient treatment resistance and favours tumour progression. How... 
Internal Medicine | Tumour metabolism | pH regulation | Autophagy | Angiogenesis | Biomedicine | Carbonic anhydrase | Oxygen-sensor | Bcl-2/adenovirus EIB 19 kDa-interacting protein 3 | Hypoxia-inducible factor | Hypoxia | Molecular Medicine | Cancer | Bcl-2/adenovirus EIB 19 kDa-interacting protein 3 | MEDICINE, RESEARCH & EXPERIMENTAL | hypoxia | CARBONIC-ANHYDRASE-IX | autophagy | INDUCIBLE FACTOR-I | HIF HYDROXYLASES | angiogenesis | tumour metabolism | C-MYC | TUMOR | hypoxia-inducible factor | BICARBONATE TRANSPORTERS | BREAST-CANCER | oxygen-sensor | GLUCOSE-METABOLISM | GENETICS & HEREDITY | carbonic anhydrase | cancer | GROWTH-FACTOR | EXPRESSION | Neoplasms - metabolism | Hypoxia - drug therapy | Cell Proliferation | Prognosis | Humans | Angiogenesis Inhibitors - pharmacology | Neoplasms - blood supply | Antineoplastic Agents - therapeutic use | Hypoxia-Inducible Factor 1 - metabolism | Oxygen - metabolism | Hypoxia - metabolism | Neoplasms - drug therapy | Cell Hypoxia | Neoplasm Metastasis | Phenotype | Animals | Signal Transduction - drug effects | Hypoxia - pathology | Cell Death | Angiogenesis Inhibitors - therapeutic use | Antineoplastic Agents - pharmacology | Neovascularization, Pathologic - metabolism | Neoplasms - pathology | Hydrogen-Ion Concentration | Development and progression | Research | DNA binding proteins | Health aspects | Risk factors | Oxygen | Anoxia | Signal Transduction | Hypoxia-Inducible Factor 1 | Biochemistry, Molecular Biology | Neovascularization, Pathologic | Antineoplastic Agents | Angiogenesis Inhibitors | Neoplasms | Life Sciences
Journal Article
Current Opinion in Genetics & Development, ISSN 0959-437X, 2010, Volume 21, Issue 1, pp. 67 - 72
The hypoxia-inducible factor (HIF-1), in addition to genetic and epigenetic changes, is largely responsible for alterations in cell metabolism in hypoxic... 
Medical Education | GLYCOLYSIS | OXYGEN | CELLS | ACTIVATION | INVASIVE GROWTH | PROTEIN-KINASE | GENETICS & HEREDITY | CARCINOMAS | AUTOPHAGY | STRESS | CANCER | CELL BIOLOGY | Cell Hypoxia | Neoplasms - metabolism | Neoplasms - therapy | Energy Metabolism | Cell Survival | Humans | Stress, Physiological | Neoplasms - pathology | Hypoxia-Inducible Factor 1 - metabolism | Life Sciences | Development Biology
Journal Article
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 03/2010, Volume 222, Issue 3, pp. 648 - 657
It is well established that cells exposed to the limiting oxygen microenvironment (hypoxia) of tumors acquire resistance to chemotherapy, through mechanisms... 
PHYSIOLOGY | FUSION | BNIP3 | MITOFUSIN-1 | DYNAMICS | DEATH | AUTOPHAGY | HIF-1-ALPHA | DYSFUNCTION | INDUCTION | BAK | CELL BIOLOGY | Neoplasms - metabolism | Apoptosis - drug effects | Humans | Drug Resistance, Neoplasm | Mitochondrial Proteins - genetics | Membrane Potential, Mitochondrial - drug effects | Cell Hypoxia | Mitochondrial Membrane Transport Proteins | Transfection | Neoplasms - genetics | RNA Interference | Time Factors | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Membrane Transport Proteins - genetics | Mitochondrial Proteins - metabolism | Adenosine Triphosphate - metabolism | Tumor Suppressor Proteins - genetics | Membrane Transport Proteins - metabolism | Membrane Proteins - metabolism | Mitochondrial Swelling | Proto-Oncogene Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Membrane Proteins - genetics | Etoposide - pharmacology | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Mitochondria - pathology | Phenotype | GTP Phosphohydrolases - metabolism | GTP Phosphohydrolases - genetics | Cell Proliferation - drug effects | HeLa Cells | Antineoplastic Agents, Phytogenic - pharmacology | Neoplasms - pathology | Staurosporine - pharmacology | Antineoplastic Agents, Phytogenic | GTP Phosphohydrolases | Cell Proliferation | Staurosporine | Adenosine Triphosphate | Mitochondrial Proteins | Hypoxia-Inducible Factor 1, alpha Subunit | Neoplasms | Life Sciences | Mitochondria | Membrane Potential, Mitochondrial | Proto-Oncogene Proteins | Etoposide | Membrane Proteins | Membrane Transport Proteins | Development Biology | Tumor Suppressor Proteins | Hela Cells | Apoptosis
Journal Article