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Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 105 - 10
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 01/2013, Volume 20, Issue 1, pp. 105 - 110
Regulated by pH, membrane-anchored proteins E and M function during dengue virus maturation and membrane fusion. Our atomic model of the whole virion from... 
Journal Article
Science Translational Medicine, ISSN 1946-6234, 06/2013, Volume 5, Issue 190, pp. 190ra79 - 190ra79
Journal Article
Cell, ISSN 0092-8674, 05/2017, Volume 169, Issue 5, pp. 891 - 904.e15
Journal Article
Cell Reports, ISSN 2211-1247, 05/2016, Volume 15, Issue 7, pp. 1514 - 1526
Journal Article
Cell, ISSN 0092-8674, 08/2018, Volume 174, Issue 4, pp. 938 - 952.e13
Journal Article
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2018, Volume 61, Issue 14, pp. 6178 - 6192
There is an urgent need for strategies to combat dengue and other emerging viral infections. We reported that cyclin G-associated kinase (GAK), a cellular... 
CLATHRIN COAT | INTERACTION MAP | CHEMISTRY, MEDICINAL | IDENTIFICATION | DENGUE VIRUS | BINDING
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, p. e0137786
DNA vaccination of transchromosomal bovines (TcBs) with DNA vaccines expressing the codon-optimized (co) glycoprotein (GP) genes of Ebola virus (EBOV) and... 
NONHUMAN-PRIMATES | EBOLA-VIRUS-INFECTION | DEFECTIVE INTERFERING VIRUS | PROPHYLAXIS | CHALLENGE | ELECTROPORATION | PARTICLES | HEMORRHAGIC-FEVER | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | INFLUENZA | Antibodies, Viral - metabolism | Hemorrhagic Fever, Ebola - prevention & control | Animals, Genetically Modified | Humans | Post-Exposure Prophylaxis - methods | Sudan | Vaccines, DNA - immunology | Cattle - genetics | Ebolavirus - immunology | Cattle - immunology | Mice, Knockout | Antibodies, Neutralizing - immunology | Animals | Vaccination - methods | Hemorrhagic Fever, Ebola - virology | Ebola Vaccines - immunology | Female | Chromosomes, Artificial, Human - genetics | Mice | Mice, Inbred BALB C | Receptor, Interferon alpha-beta - genetics | Democratic Republic of the Congo | Ebola virus | Virus diseases | Prevention | Research | Virus research | Epidemics | Immunoglobulin G | Vaccination | Antibodies | Viruses | Infections | DNA vaccines | Vaccines | Immunology | Cattle | Deoxyribonucleic acid--DNA | Polyclonal antibodies | Enzyme-linked immunosorbent assay | Recombinant | Antigens | Medical research | Immunoglobulins | Glycoprotein | Electroporation | Exposure | Artificial chromosomes | Injection | Gene expression | Fever | Virology | Stomatitis | Infectious diseases | Influenza | Neutralizing | Interferon | Neutralization | Deoxyribonucleic acid | DNA
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 08/2018, Volume 24, Issue 2, pp. 221 - 233.e5
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 2019, Volume 62, Issue 12, pp. 5810 - 5831
There are currently no approved drugs for the treatment of emerging viral infections, such as dengue and Ebola. Adaptor-associated kinase 1 (AAK1) is a... 
SYSTEM | POTENT | CHEMISTRY, MEDICINAL | ENTRY | OPTIMIZATION | DISCOVERY | SCAFFOLD
Journal Article