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by Ardlie, K. G and Deluca, D. S and Segre, A. V and Sullivan, T. J and Young, T. R and Gelfand, E. T and Trowbridge, C. A and Maller, J. B and Tukiainen, T and Lek, M and Ward, L. D and Kheradpour, P and Iriarte, B and Meng, Y and Palmer, C. D and Esko, T and Winckler, W and Hirschhorn, J. N and Kellis, M and MacArthur, D. G and Getz, G and Shabalin, A. A and Li, G and Zhou, Y.-H and Nobel, A. B and Rusyn, I and Wright, F. A and Lappalainen, T and Ferreira, P. G and Ongen, H and Rivas, M. A and Battle, A and Mostafavi, S and Monlong, J and Sammeth, M and Mele, M and Reverter, F and Goldmann, J. M and Koller, D and Guigo, R and McCarthy, M. I and Dermitzakis, E. T and Gamazon, E. R and Im, H. K and Konkashbaev, A and Nicolae, D. L and Cox, N. J and Flutre, T and Wen, X and Stephens, M and Pritchard, J. K and Tu, Z and Zhang, B and Huang, T and Long, Q and Lin, L and Yang, J and Zhu, J and Liu, J and Brown, A and Mestichelli, B and Tidwell, D and Lo, E and Salvatore, M and Shad, S and Thomas, J. A and Lonsdale, J. T and Moser, M. T and Gillard, B. M and Karasik, E and Ramsey, K and Choi, C and Foster, B. A and Syron, J and Fleming, J and Magazine, H and Hasz, R and Walters, G. D and Bridge, J. P and Miklos, M and Sullivan, S and Barker, L. K and Traino, H. M and Mosavel, M and Siminoff, L. A and Valley, D. R and Rohrer, D. C and Jewell, S. D and Branton, P. A and Sobin, L. H and Barcus, M and Qi, L and McLean, J and Hariharan, P and Um, K. S and Wu, S and Tabor, D and Shive, C and Smith, A. M and Buia, S. A and ... and The GTEx Consortium and GTEx Consortium
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2015, Volume 348, Issue 6235, pp. 648 - 660
Journal Article
by Battle, Alexis and Brown, Christopher D and Engelhardt, Barbara E and Montgomery, Stephen B and Aguet, François and Ardlie, Kristin G and Cummings, Beryl B and Gelfand, Ellen T and Getz, Gad and Hadley, Kane and Handsaker, Robert E and Huang, Katherine H and Kashin, Seva and Karczewski, Konrad J and Lek, Monkol and Li, Xiao and MacArthur, Daniel G and Nedzel, Jared L and Nguyen, Duyen T and Noble, Michael S and Segrè, Ayellet V and Trowbridge, Casana A and Tukiainen, Taru and Abell, Nathan S and Balliu, Brunilda and Barshir, Ruth and Basha, Omer and Bogu, Gireesh K and Brown, Anew and Castel, Stephane E and Chen, Lin S and Chiang, Colby and Conrad, Donald F and Cox, Nancy J and Damani, Farhan N and Davis, Joe R and Delaneau, Olivier and Dermitzakis, Emmanouil T and Eskin, Eleazar and Ferreira, Peo G and Frésard, Laure and Gamazon, Eric R and Garrido-Martín, Diego and Gewirtz, Ariel D. H and Gliner, Genna and Gloudemans, Michael J and Guigo, Roderic and Hall, Ira M and Han, Buhm and He, Yuan and GTEx Consortium and Pathology and Laboratory Data Analysis and Lab Data Anal Coordinating Ct and Stat Methods Grps-Anal Working Grp and Biospecimen Collection Source Sit and Genome Browser Data Integration and Biospecimen Core Resource-Vari and Leidos Biomedical-Project and Genome Browser Data Integr and Enhancing Gtex Egtex Grps and Gtex Consortium and Biospecimen Collection Source and Brain Bank Repository-Univ M and Leidos Biomedical—Project Management and Laboratory, Data Analysis &Coordinating Center (LDACC) and NIH/NCI and Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group and Statistical Methods groups—Analysis Working Group and Biospecimen Collection Source Site—NDRI and NIH/NHGRI and Brain Bank Repository—University of Miami Brain Endowment Bank and Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz and NIH Common Fund and Enhancing GTEx (eGTEx) groups and NIH/NIMH and Genome Browser Data Integration &Visualization—EBI and Lead analysts and Biospecimen Collection Source Site—RPCI and Biospecimen collection and Biospecimen Core Resource—VARI and NIH program management and eQTL manuscript working group and ELSI Study and NIH/NIDA
Nature (London), ISSN 1476-4687, 2017, Volume 550, Issue 7675, pp. 204 - 213
Journal Article
Nature (London), ISSN 1476-4687, 2017, Volume 550, Issue 7675, pp. 249 - 254
Journal Article
Oncogene, ISSN 0950-9232, 2012, Volume 32, Issue 13, pp. 1626 - 1637
Since the discovery of post-translational modification (PTM) by the small ubiquitin-related modifiers (SUMOs), a multitude of proteins have been described to... 
Phosphorylation | Transformation | SUMO | Oncoprotein | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTIONAL REPRESSION | E1B 55-KILODALTON PROTEIN | NUCLEAR EXPORT | VIRAL INCLUSIONS | SUMO-1 MODIFICATION | transformation | CELL BIOLOGY | E1B-58KD TUMOR-ANTIGEN | CELL-TRANSFORMATION | ONCOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | INFECTED-CELLS | phosphorylation | oncoprotein | DEPENDENT DEGRADATION | Phosphorylation - physiology | Protein Kinases - metabolism | Humans | Protein Processing, Post-Translational - genetics | Molecular Sequence Data | Sumoylation - physiology | Phylogeny | Receptor Cross-Talk - physiology | Viral Proteins - metabolism | Tumor Suppressor Protein p53 - physiology | Phosphorylation - genetics | Cell Transformation, Neoplastic - genetics | HEK293 Cells | Viral Proteins - physiology | Adenoviridae - genetics | Animals, Newborn | Amino Acid Sequence | Sumoylation - genetics | Viral Proteins - chemistry | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Rats | Viral Proteins - genetics | Nuclear Proteins - metabolism | Cell Transformation, Neoplastic - metabolism | Protein Processing, Post-Translational - physiology | Sequence Homology, Amino Acid | Adaptor Proteins, Signal Transducing - physiology | Animals | Models, Biological | Protein Kinases - physiology | Nuclear Proteins - physiology | Adenoviridae - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Post-translational modification | Viral proteins | Adenovirus diseases | Physiological aspects | Genetic aspects | Research | Health aspects | Proteins | Enzymes | Oncology
Journal Article
by Lonsdale, John and Thomas, Jeffrey and Salvatore, Mike and Phillips, Rebecca and Lo, Edmund and Shad, Saboor and Hasz, Richard and Walters, Gary and Garcia, Fernando and Young, Nancy and Foster, Barbara and Moser, Mike and Karasik, Ellen and Gillard, Bryan and Ramsey, Kimberley and Sullivan, Susan and Bridge, Jason and Magazine, Harold and Syron, John and Fleming, Johnelle and Siminoff, Laura and Traino, Heather and Mosavel, Maghboeba and Barker, Laura and Jewell, Scott and Rohrer, Dan and Maxim, Dan and Filkins, Dana and Harbach, Philip and Cortadillo, Eddie and Berghuis, Bree and Turner, Lisa and Hudson, Eric and Feenstra, Kristin and Sobin, Leslie and Robb, James and Branton, Phillip and Korzeniewski, Greg and Shive, Charles and Tabor, David and Qi, Liqun and Groch, Kevin and Nampally, Sreenath and Buia, Steve and Zimmerman, Angela and Smith, Anna and Burges, Robin and Robinson, Karna and Valentino, Kim and Bradbury, Deborah and Cosentino, Mark and Diaz-Mayoral, Norma and Kennedy, Mary and Engel, Theresa and Williams, Penelope and Erickson, Kenyon and Ardlie, Kristin and Winckler, Wendy and Getz, Gad and DeLuca, David and MacArthur, Daniel and Kellis, Manolis and Thomson, Alexander and Young, Taylor and Gelfand, Ellen and Donovan, Molly and Meng, Yan and Grant, George and Mash, Deborah and Marcus, Yvonne and Basile, Margaret and Liu, Jun and Zhu, Jun and Tu, Zhidong and Cox, Nancy J and Nicolae, Dan L and Gamazon, Eric R and Im, Hae Kyung and Konkashbaev, Anuar and Pritchard, Jonathan and Stevens, Matthew and Flutre, Timothèe and Wen, Xiaoquan and Dermitzakis, Emmanouil T and Lappalainen, Tuuli and Guigo, Roderic and Monlong, Jean and Sammeth, Michael and Koller, Daphne and Battle, Alexis and Mostafavi, Sara and McCarthy, Mark and Rivas, Manual and Maller, Julian and Rusyn, Ivan and Nobel, Andrew and Wright, Fred and Shabalin, Andrey and Feolo, Mike and Sharopova, Nataliya and ... and GTEx Consortium
Nature genetics, ISSN 1546-1718, 2013, Volume 45, Issue 6, pp. 580 - 585
Journal Article
by Rivas, M. A and Pirinen, M and Conrad, D. F and Lek, M and Tsang, E. K and Karczewski, K. J and Maller, J. B and Kukurba, K. R and DeLuca, D. S and Fromer, M and Ferreira, P. G and Smith, K. S and Zhang, R and Zhao, F and Banks, E and Poplin, R and Ruderfer, D. M and Purcell, S. M and Tukiainen, T and Minikel, E. V and Stenson, P. D and Cooper, D. N and Huang, K. H and Sullivan, T. J and Nedzel, J and Bustamante, C. D and Li, J. B and Daly, M. J and Guigo, R and Donnelly, P and Ardlie, K and Sammeth, M and Dermitzakis, E. T and McCarthy, M. I and Montgomery, S. B and Lappalainen, T and MacArthur, D. G and Segre, A. V and Young, T. R and Gelfand, E. T and Trowbridge, C. A and Ward, L. D and Kheradpour, P and Iriarte, B and Meng, Y and Palmer, C. D and Esko, T and Winckler, W and Hirschhorn, J and Kellis, M and Getz, G and Shablin, A. A and Li, G and Zhou, Y.-H and Nobel, A. B and Rusyn, I and Wright, F. A and Battle, A and Mostafavi, S and Mele, M and Reverter, F and Goldmann, J and Koller, D and Gamazon, E. R and Im, H. K and Konkashbaev, A and Nicolae, D. L and Cox, N. J and Flutre, T and Wen, X and Stephens, M and Pritchard, J. K and Tu, Z and Zhang, B and Huang, T and Long, Q and Lin, L and Yang, J and Zhu, J and Liu, J and Brown, A and Mestichelli, B and Tidwell, D and Lo, E and Salvatore, M and Shad, S and Thomas, J. A and Lonsdale, J. T and Choi, R. C and Karasik, E and Ramsey, K and Moser, M. T and Foster, B. A and Gillard, B. M and Syron, J and Fleming, J and Magazine, H and Hasz, R and Walters, G. D and Bridge, J. P and ... and The Geuvadis Consortium and The GTEx Consortium and GTEx Consortium and Geuvadis Consortium
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2015, Volume 348, Issue 6235, pp. 666 - 669
Accurate prediction of the functional effect of genetic variation is critical for clinical genome interpretation. We systematically characterized the... 
EXPRESSION | MULTIDISCIPLINARY SCIENCES | DOSAGE | Genetic variation | Identification and classification | Genetic transcription | Proteins | Genotype & phenotype | Transcription factors | Genetic diversity | Gene expression | Consortia | Genes | Decay | Genetics | Genomes | Mathematical models | Robustness
Journal Article