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British Journal of Clinical Pharmacology, ISSN 0306-5251, 09/2019, Volume 85, Issue 9, p. 1874
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 09/2019, Volume 85, Issue 9, pp. 1874 - 1877
Radically expanding use of real‐world data (RWD) and real‐world evidence (RWE) holds the potential to substantially impact drug development, pharmaceutical... 
real‐world evidence | real‐world data | Index Medicus
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2015, Volume 108, Issue 2, pp. 350a - 350a
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2015, Volume 108, Issue 2, p. 350
(2) MRC National Institiute for Medical Research, London, United Kingdom 
Journal Article
British Journal of Hospital Medicine, ISSN 1750-8460, 2010, Volume 71, Issue 10, pp. 544 - 545
Journal Article
Journal of Cardiovascular Development and Disease, ISSN 2308-3425, 03/2014, Volume 1, Issue 1, pp. 29 - 36
Immediately following birth, the mammalian heart switches from generating ATP via glycolysis to β-oxidation of lipid. Coincident with this metabolic... 
neonatal | metabolism | HIF | PPAR | cardiac
Journal Article
PLoS Biology, ISSN 1544-9173, 09/2013, Volume 11, Issue 9, pp. e1001666 - e1001666
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2014, Volume 74, Issue 100, pp. 340 - 352
Abstract Fetal cardiomyocyte adaptation to low levels of oxygen in utero is incompletely understood, and is of interest as hypoxia tolerance is lost after... 
Cardiovascular | Hypoxia | Neonatal | Mitochondria | Mitofusin | Cardiac | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | PGC-1-ALPHA | METABOLIC ADAPTATION | CELL BIOLOGY | HEART | INDUCIBLE FACTORS | BIOENERGETICS | RESPIRATION | FETAL | DIFFERENTIATION | EXPRESSION | Adaptation, Physiological | Mitochondria, Heart - ultrastructure | Oxygen - pharmacology | Heart Ventricles - cytology | Mitochondria, Heart - metabolism | Mitochondrial Dynamics - genetics | Embryo, Mammalian | Mitochondrial Proteins - genetics | Mitochondria, Heart - drug effects | Adenosine Triphosphate - biosynthesis | Membrane Potential, Mitochondrial - drug effects | Glycolysis - drug effects | Oxygen - metabolism | Hypoxia - metabolism | Glycolysis - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Mitochondrial Proteins - metabolism | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Animals, Newborn | Basic Helix-Loop-Helix Transcription Factors - genetics | Myocytes, Cardiac - cytology | Signal Transduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Citric Acid Cycle - drug effects | Mice, Transgenic | Citric Acid Cycle - genetics | Hypoxia - genetics | Animals | Mitochondrial Dynamics - drug effects | Myocytes, Cardiac - drug effects | Myocytes, Cardiac - metabolism | Heart Ventricles - metabolism | Mice | Heart Ventricles - drug effects | Mitochondrial DNA | Index Medicus | MFN, Mitofusin | Pgc1, Peroxisome proliferator-activated receptor gamma co-activator 1 | VHL, Von Hippel–Lindau factor | TMRM, Tetramethylrhodamine, methyl ester | Original | HIF, Hypoxia inducible factor
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 04/2013, Volume 57, p. 129
M.sub.2 muscarinic acetylcholine receptors modulate cardiac rhythm via regulation of the inward potassium current. To increase our understanding of M.sub.2... 
Monte Carlo method | Analysis | Physiological aspects | Fluorescence
Journal Article
by McGhee, D. J. M and Royle, P. L and Counsell, C. E and Abbas, A and Sethi, P and Manku, L and Narayan, A and Clegg, K and Bardai, A and Brown, S. H. M and Hafeez, U and Abdelhafiz, A. H and McGovern, A and Breckenridge, A and Seenan, P and Samani, A and Das, S and Khan, S and Puffett, A. J and Morgan, J and Ross, G and Cantlay, A and Khan, N and Bhalla, A and Sweeting, M and Nimmo, C. A. M. D and Fleet, J and Igbedioh, C and Harari, D and Downey, C. L and Handforth, C and Stothard, C and Cracknell, A and Barnes, C and Shaw, L and Bainbridge, L and Crabtree, L and Clark, T and Root, S and Aitken, E and Haroon, K and Sudlow, M and Hanley, K and Welsh, S and Hill, E and Falconer, A and Miller, H and Martin, B and Tidy, E and Pendlebury, S and Thompson, S and Burnett, E and Taylor, H and Lonan, J and Adler, B and McCallion, J and Sykes, E and Bancroft, R and Tullo, E. S and Young, T. J and Clift, E and Flavin, B and Roberts, H. C and Sayer, A. A and Belludi, G and Aithal, S and Verma, A and Singh, I and Barne, M and Wilkinson, I and Sakoane, R and Singh, N and Cottee, M and Irani, T. S and Martinovic, O and Abdulla, A. J. J and Riglin, J and Husk, J and Lowe, D and Treml, J and Vasilakis, J. N and Buttery, A and Reid, J and Healy, P and Grant-Casey, J and Pendry, K and Richards, J and Singh, A and Jarrett, D and Hewitt, J and Slevin, J and Barwell, G and Youde, J and Kennedy, C and Romero-Ortuno, R and O'Shea, D and Robinson, D and Kenny, R. A and O'Connell, J and Topp, J. D and ...
Age and Ageing, ISSN 0002-0729, 03/2013, Volume 42, Issue suppl 2, pp. ii5 - ii16
Journal Article
Annals of Medicine and Surgery, ISSN 2049-0801, 2013, Volume 2, Issue 1, pp. 1 - 2
Journal Article
PLoS Biology, ISSN 1544-9173, 09/2013, Volume 11, Issue 9
  Cardiomyocytes are vulnerable to hypoxia in the adult, but adapted to hypoxia in utero. Current understanding of endogenous cardiac oxygen sensing pathways... 
Proteins | Heart failure | Enzymes | Heart attacks | Metabolites | Ontology | Heart surgery | Lipids | Hypoxia | Cardiomyocytes | Metabolism | Gene expression
Journal Article
F1000Research, ISSN 2046-1402, 11/2013, Volume 2, p. 242
For the majority of organs in developing vertebrate embryos, left-right asymmetry is controlled by a ciliated region; the left-right organizer node in the... 
Bioinformatics | Pattern Formation
Journal Article
International Journal of Developmental Biology, ISSN 0214-6282, 2010, Volume 54, Issue 1, pp. 215 - 220
Nitric oxide has been linked to a number of embryonic processes, yet the role of nitric oxide signalling in development remains largely unknown.... 
DDAH | Transgenic | Embryonic development | Mouse | Nitric oxide | nitric oxide | embryonic development | NITRIC-OXIDE SYNTHASE | CELL-PROLIFERATION | DEVELOPMENTAL BIOLOGY | TROPHOBLAST | mouse | REGULATOR | DISRUPTION | IMPLANTATION | PATHWAY | ENDOTHELIAL-CELLS | GROWTH | transgenic | EXPRESSION
Journal Article
Journal Article
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