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Kidney International, ISSN 0085-2538, 03/2018, Volume 93, Issue 3, pp. 580 - 588
The tight junction proteins claudin-10 and -16 are crucial for the paracellular reabsorption of cations along the thick ascending limb of Henle’s loop in the... 
paracellular pathway | magnesium | calcium | thick ascending limb | claudin | tight junction | PERMEABILITY | MG2+ TRANSPORT | PARACELLULAR NA+ | UROLOGY & NEPHROLOGY | NEPHROCALCINOSIS | MUTATIONS | HENLES LOOP | EXPRESSION | REABSORPTION | CATION | Kidney Tubules, Distal - pathology | Magnesium Deficiency - physiopathology | Calcium - metabolism | Claudins - deficiency | Loop of Henle - metabolism | Loop of Henle - pathology | Sodium - metabolism | Nephrocalcinosis - physiopathology | Magnesium Deficiency - genetics | Nephrocalcinosis - metabolism | Gene Deletion | Hypercalciuria - prevention & control | Nephrocalcinosis - prevention & control | Hypercalciuria - genetics | Magnesium Deficiency - prevention & control | Disease Models, Animal | Claudins - genetics | Genetic Predisposition to Disease | Hypercalciuria - physiopathology | Mice, Inbred C57BL | Loop of Henle - physiopathology | Magnesium - metabolism | Magnesium Deficiency - metabolism | Mice, Knockout | Phenotype | Animals | Nephrocalcinosis - genetics | Hypercalciuria - metabolism | Kidney Tubules, Distal - physiopathology | Kidney Tubules, Distal - metabolism | Urine | Phosphorylation | Excretion | Renal function | Kidneys | Calcium | Tubules | Reabsorption | Permeability | Gene expression | Hypercalciuria | Clonal deletion | Sodium | Calcinosis | Rodents | Hypermagnesemia | Mutation | Magnesium | Kidney diseases | Polyuria | Potassium | Hypomagnesemia | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2012, Volume 109, Issue 35, pp. 14241 - 14246
Journal Article
Nature Neuroscience, ISSN 1097-6256, 11/2007, Volume 10, Issue 11, pp. 1449 - 1457
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2005, Volume 102, Issue 38, pp. 13461 - 13466
Journal Article
PLoS Genetics, ISSN 1553-7390, 07/2017, Volume 13, Issue 7, pp. e1006897 - e1006897
Claudins constitute the major component of tight junctions and regulate paracellular permeability of epithelia. Claudin-10 occurs in two major isoforms that... 
CLAUDINS | BARRIER | DISEASE | GENETICS & HEREDITY | ARCHITECTURE | TIGHT JUNCTION PROTEINS | CHANNELS | MUTATIONS | MODEL | SECRETION | EXPRESSION | Claudins - genetics | Renal Insufficiency - genetics | Epithelial Cells - metabolism | Kidney - pathology | Cations - metabolism | Humans | Hypohidrosis | Renal Insufficiency - metabolism | Mutation, Missense | Permeability | Microscopy, Electron | Kidney - metabolism | Animals | Claudins - metabolism | Protein Isoforms - metabolism | Renal Insufficiency - pathology | Tight Junctions | Biological Transport - genetics | Mice | Protein Isoforms - genetics | Causes of | Genetic aspects | Hyperhidrosis | Genetic variation | Health aspects | Visualization | Biotechnology | Membranes | Laboratories | Funding | Syngeneic grafts | Glands | Science | Homeostasis | Selectivity | Proteins | Immunology | Missense mutation | Physiology | Magnesium | Sweat | Supervision | Kidneys | Tight junctions | Secretion | Reabsorption | Roles | Electron microscopy | Hereditary diseases | Resistance | Pathology | Intolerance | Isoforms | Plasma membranes | Renal failure | Software | Cations | Genetic engineering | Conductance | Mutation | Three dimensional models | Hyperparathyroidism | Kidney transplantation | Index Medicus | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, pp. e75006 - e75006
Journal Article
EMBO reports, ISSN 1469-221X, 04/2018, Volume 19, Issue 4, pp. e44810 - n/a
SORCS 1 and SORCS 3 are two related sorting receptors expressed in neurons of the arcuate nucleus of the hypothalamus. Using mouse models with individual or... 
agouti‐related peptide | VPS | 10P domain receptors | adiposity | TrkB | brain‐derived neurotrophic factor | brain-derived neurotrophic factor | VPS10P domain receptors | agouti-related peptide | LEPTIN | HIGH-FAT | PROTEIN | BDNF | FOOD-INTAKE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | CELL BIOLOGY | OBESITY | DIET | AGRP GENE-EXPRESSION | NEUROPEPTIDE EXPRESSION | Gene Expression | Age Factors | Homeostasis | Receptors, Cell Surface - metabolism | Adiposity - genetics | Nerve Tissue Proteins - genetics | Mice, Knockout | Brain - metabolism | Nerve Tissue Proteins - metabolism | Animals | Hypothalamus - metabolism | Models, Biological | Body Composition - genetics | Glucose - metabolism | Brain-Derived Neurotrophic Factor - metabolism | Mice | Neurons - metabolism | Energy Metabolism - genetics | Genes, Reporter | Receptors, Cell Surface - genetics | Brain | Animal models | Adipose tissue | Transcription | Peptides | Body weight | Arcuate nucleus | Trafficking | Intracellular signalling | Lipids | Hypothalamus | Kinases | Proteins | Receptors | KLF4 protein | Energy | Rodents | Lipid metabolism | Protein transport | Locomotor activity | Neurons | Tropomyosin | Diabetes mellitus | Melanocortin | Metabolism | Energy balance | Brain-derived neurotrophic factor | Food intake | Weight reduction | Sensitivity enhancement | TrkB receptors | Receptor mechanisms | Index Medicus | Neuroscience
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2017, Volume 114, Issue 2, pp. E219 - E227
Journal Article
Gastroenterology, ISSN 0016-5085, 04/2017, Volume 152, Issue 5, pp. S967 - S967
Journal Article
Cell Metabolism, ISSN 1550-4131, 09/2010, Volume 12, Issue 3, pp. 213 - 223
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 03/2016, Volume 31, Issue 3, pp. 498 - 513
Journal Article
Journal Article
Frontiers in Physiology, ISSN 1664-042X, 05/2017, Volume 8, Issue MAY, pp. 326 - 326
Claudins are a family of proteins that forms paracellular barriers and pores determining tight junctions (TJ) permeability. Claudin-16 and -19 are pore forming... 
Pore-forming tight junction protein | Claudins | Barrier-forming tight junction protein | Enamel | Amelogenesis Imperfecta | PHYSIOLOGY | pore-forming tight junction protein | enamel | AMELOBLASTS | claudins | KIDNEY | barrier-forming tight junction protein | Life Sciences | Human health and pathology | Tissues and Organs
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 01/2017, Volume 114, Issue 2, pp. E219 - E227
The thick ascending limb (TAL) of Henle's loop drives paracellular Na+, Ca2+, and Mg2+ reabsorption via the tight junction (TJ). The TJ is composed of claudins... 
LOCALIZATION | paracellular ion transport | DIFFERENTIAL EXPRESSION | NEPHRON SEGMENTS | MULTIDISCIPLINARY SCIENCES | LOOP | microperfusion | claudin interaction | MAGNESIUM | MOUSE NEPHRON | FRET | TIGHT JUNCTION PROTEINS | KIDNEY | SELECTIVITY | REABSORPTION | tight junction | Index Medicus | Biological Sciences | PNAS Plus
Journal Article