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1. Full Text Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
by Grundy, Scott M and Cleeman, James I and Bairey Merz, C. Noel and Brewer, H. Bryan and Clark, Luther T and Hunninghake, Donald B and Pasternak, Richard C and Smith, Sidney C and Stone, Neil J and Coordinating Committee of the National Cholesterol Education Program
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2004, Volume 44, Issue 3, pp. 720 - 732
The Adult Treatment Panel III (ATP III) of the National Cholesterol Education Program issued an evidence-based set of guidelines on cholesterol management in... 
coronary disease | cholesterol | trials | lipoproteins | Clinical Trials as Topic - statistics & numerical data | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Hypertension - drug therapy | Risk | Cardiovascular Diseases - epidemiology | Cholesterol, LDL - blood | Hypercholesterolemia - prevention & control | Hypertension - epidemiology | Hypercholesterolemia - epidemiology | Patient Education as Topic | Randomized Controlled Trials as Topic - statistics & numerical data | Comorbidity | Risk Factors | Antihypertensive Agents - therapeutic use | Evidence-Based Medicine | Anticholesteremic Agents - therapeutic use | Myocardial Infarction - drug therapy | Diabetes Mellitus - epidemiology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Thrombolytic Therapy | Aged | Hypolipidemic Agents - therapeutic use | Practice Guidelines as Topic | Anticholesteremic agents | Studies | Heart attacks | Algorithms | Risk assessment | Clinical trials | Cardiovascular disease | Lipids | Triglycerides | Drug therapy | Low density lipoprotein | Cholesterol
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2. Full Text Definition of Metabolic Syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition
by Grundy, Scott M and Brewer Jr, H. Bryan and Cleeman, James I and Smith Jr, Sidney C and Lenfant, Claude and Conference Participants and National Heart, Lung, and Blood Institute and American Heart Association
Circulation, ISSN 0009-7322, 01/2004, Volume 109, Issue 3, pp. 433 - 438
Obesity | Cardiovascular diseases | Metabolic syndrome | Diabetes mellitus | AHA Scientific Statements | metabolic syndrome | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | INSULIN-RESISTANCE | DISEASE | PERIPHERAL VASCULAR DISEASE | diabetes mellitus | cardiovascular diseases | obesity | Cardiovascular Diseases - etiology | Metabolic Syndrome - etiology | Prognosis | Metabolic Syndrome - diagnosis | Humans | Risk Factors | Obesity - therapy | Terminology as Topic | Diabetes Mellitus - etiology | Metabolic Syndrome - therapy | Metabolic Syndrome - complications
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3. Full Text The Evolving Role of HDL in the Treatment of High-Risk Patients with Cardiovascular Disease
by Brewer, H. Bryan
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 05/2011, Volume 96, Issue 5, pp. 1246 - 1257
Clinical studies and animal models have suggested that increasing HDL will reduce atherosclerosis and decrease clinical events in high-risk cardiovascular... 
INTIMA-MEDIA THICKNESS | ATP-BINDING CASSETTE | ESTER TRANSFER PROTEIN | EXTENDED-RELEASE NIACIN/LAROPIPRANT | ENDOCRINOLOGY & METABOLISM | CELLULAR CHOLESTEROL EFFLUX | RANDOMIZED CONTROLLED-TRIAL | OFF-TARGET TOXICITY | CORONARY-HEART-DISEASE | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-A-I
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4. Full Text Dysfunctional HDL and atherosclerotic cardiovascular disease
by Rosenson, Robert S and Brewer, H. Bryan and Ansell, Benjamin J and Barter, Philip and Chapman, M. John and Heinecke, Jay W and Kontush, Anatol and Tall, Alan R and Webb, Nancy R
Nature Reviews Cardiology, ISSN 1759-5002, 01/2016, Volume 13, Issue 1, pp. 48 - 60
High-density lipoproteins (HDLs) protect against atherosclerosis by removing excess cholesterol from macrophages through the ATP-binding cassette transporter... 
EFFLUX CAPACITY | ACUTE-PHASE RESPONSE | CARDIAC & CARDIOVASCULAR SYSTEMS | ANTIINFLAMMATORY PROPERTIES | ACTIVATING-FACTOR ACETYLHYDROLASE | REVERSE CHOLESTEROL TRANSPORT | SERUM-AMYLOID-A | ELEVATED OXIDATIVE STRESS | CORONARY-ARTERY-DISEASE | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-A-I | Smoking - adverse effects | Smoking - metabolism | Apolipoprotein A-I - genetics | Macrophages - metabolism | Lipoproteins, HDL - genetics | Atherosclerosis - physiopathology | Diabetes Complications - metabolism | Humans | Lipoproteins, HDL - metabolism | ATP-Binding Cassette Transporters - metabolism | Apolipoprotein A-I - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Care and treatment | Diagnosis | Cardiovascular research | High density lipoproteins | Health aspects | Atherosclerosis
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5. Full Text HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events
by Rosenson, Robert S and Brewer Jr, H. Bryan and Chapman, M. John and Fazio, Sergio and Hussain, M. Mahmood and Kontush, Anatol and Krauss, Ronald M and Otvos, James D and Remaley, Alan T and Schaefer, Ernst J
Clinical Chemistry, ISSN 0009-9147, 03/2011, Volume 57, Issue 3, pp. 392 - 410
BACKGROUND: A growing body of evidence from epidemiological data, animal studies, and clinical trials supports HDL as the next target to reduce residual... 
MAGNETIC-RESONANCE-SPECTROSCOPY | SELECTIVE LIPID UPTAKE | TRANSFER PROTEIN INHIBITOR | PLASMA-LIPOPROTEINS | CHOLESTERYL ESTER TRANSFER | FRACTIONAL CATABOLIC RATE | MEDICAL LABORATORY TECHNOLOGY | CORONARY-HEART-DISEASE | EXTENDED-RELEASE NIACIN | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-A-I | Blood Chemical Analysis - methods | Predictive Value of Tests | Centrifugation, Density Gradient | Magnetic Resonance Spectroscopy | Lipoproteins, HDL - blood | Humans | Risk Factors | Terminology as Topic | Electrophoresis, Gel, Two-Dimensional | Immunoblotting | Apolipoproteins B - blood | Blood Chemical Analysis - instrumentation | Apolipoprotein A-II - blood | Blood Chemical Analysis - standards | Atherosclerosis - blood | Lipoproteins, HDL - classification | Sensitivity and Specificity | Cardiovascular Diseases - blood | Apolipoprotein A-I - blood | Proteins | Studies | Mortality | Atherosclerosis | Atoms & subatomic particles | Cardiovascular disease | Lipids | Clinical medicine | Cholesterol | Statins
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6. Full Text Translation of High-Density Lipoprotein Function Into Clinical Practice: Current Prospects and Future Challenges
by Rosenson, Robert S and Brewer, H Bryan and Ansell, Benjamin and Barter, Philip and Chapman, M John and Heinecke, Jay W and Kontush, Anatol and Tall, Alan R and Webb, Nancy R
Circulation, ISSN 0009-7322, 09/2013, Volume 128, Issue 11, pp. 1256 - 1267
atherosclerosis | HUMAN-PLASMA | lipids | CARDIAC & CARDIOVASCULAR SYSTEMS | NITRIC-OXIDE SYNTHASE | ENDOTHELIUM-DEPENDENT VASORELAXATION | cardiovascular diseases | BINDING CASSETTE TRANSPORTERS | SCAVENGER RECEPTOR-BI | CELLULAR FREE-CHOLESTEROL | inflammation | REVERSE CHOLESTEROL TRANSPORT | PERIPHERAL VASCULAR DISEASE | HDL-CHOLESTEROL | CORONARY-HEART-DISEASE | lipoproteins | APOLIPOPROTEIN-A-I | Lipoproteins, HDL - blood | Cardiovascular Diseases - prevention & control | Humans | Risk | Apolipoproteins B - blood | Structure-Activity Relationship | Blood Chemical Analysis - standards | Lipoproteins, HDL - classification | Lipids - blood | Cardiovascular Diseases - blood | Lipoproteins, HDL - chemistry | Models, Animal | Blood Chemical Analysis - methods | Reproducibility of Results | Clinical Trials as Topic | Translational Medical Research - trends | Cholesterol - metabolism | Forecasting | Lipoproteins, HDL - physiology | Atherosclerosis - blood | Blood Proteins - analysis | Particle Size | Macrophages - metabolism | Animals | Anticholesteremic Agents - therapeutic use | Validation Studies as Topic | Biomarkers | Anticholesteremic Agents - pharmacology | Lipoproteins, LDL - blood | Clinical trials | Research | High density lipoproteins | Health aspects | Analysis
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7. Full Text The impact of proprotein convertase subtilisin-kexin type 9 serine protease inhibitors on lipid levels and outcomes in patients with primary hypercholesterolaemia: A network meta-analysis
by Lipinski, Michael J and Benedetto, Umberto and Escarcega, Ricardo O and Biondi-Zoccai, Giuseppe and Lhermusier, Thibault and Baker, Nevin C and Torguson, Rebecca and Brewer, H. Bryan and Waksman, Ron
European Heart Journal, ISSN 0195-668X, 02/2016, Volume 37, Issue 6, pp. 536 - 545
Aims We performed a network meta-analysis of randomized controlled trials (RCTs) in patients with primary hypercholesterolaemia to compare the impact of... 
PCSK9 inhibitors | Hypercholesterolemia | Lipid levels | Outcomes | CARDIAC & CARDIOVASCULAR SYSTEMS | EVOLOCUMAB AMG 145 | LDL-C | MONOCLONAL-ANTIBODY | HIGH CARDIOVASCULAR RISK | DENSITY-LIPOPROTEIN CHOLESTEROL | HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA | PCSK9 INHIBITION | DOUBLE-BLIND | EVERY 2 WEEKS | STATIN-INTOLERANT PATIENTS | Anticholesteremic Agents - therapeutic use | Proprotein Convertase 9 - antagonists & inhibitors | Humans | Cholesterol, LDL - metabolism | Cholesterol, LDL - drug effects | Treatment Outcome | Network Meta-Analysis | Hypercholesterolemia - drug therapy | Randomized Controlled Trials as Topic
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8. Full Text Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
by Grundy, Scott M and Cleeman, James I and Bairey Merz, C. Noel and Brewer Jr, H. Bryan and Clark, Luther T and Hunninghake, Donald B and Pasternak, Richard C and Smith Jr, Sidney C and Stone, Neil J and Coordinating Comm Natl Cholesterol and American College of Cardiology Foundation and National Heart, Lung, and Blood Institute and American Heart Association
Circulation, ISSN 0009-7322, 07/2004, Volume 110, Issue 2, pp. 227 - 239
The Adult Treatment Panel III (ATP III) of the National Cholesterol Education Program issued an evidence-based set of guidelines on cholesterol management in... 
Lipoproteins | Trials | Coronary disease | Cholesterol | CARDIAC & CARDIOVASCULAR SYSTEMS | SERUM-CHOLESTEROL | MYOCARDIAL-INFARCTION | CARDIOVASCULAR EVENTS | PREVENTION | LIPID-LOWERING THERAPY | SUBGROUP-ANALYSES | ATORVASTATIN | coronary disease | DENSITY-LIPOPROTEIN CHOLESTEROL | trials | cholesterol | PERIPHERAL VASCULAR DISEASE | PRAVASTATIN | CORONARY-HEART-DISEASE | lipoproteins | Clinical Trials as Topic - statistics & numerical data | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Hypertension - drug therapy | Risk | Cardiovascular Diseases - epidemiology | Cholesterol, LDL - blood | Hypercholesterolemia - prevention & control | Hypertension - epidemiology | Hypercholesterolemia - epidemiology | Patient Education as Topic | Randomized Controlled Trials as Topic - statistics & numerical data | Comorbidity | Risk Factors | Antihypertensive Agents - therapeutic use | Evidence-Based Medicine | Anticholesteremic Agents - therapeutic use | Myocardial Infarction - drug therapy | Diabetes Mellitus - epidemiology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Thrombolytic Therapy | Aged | Hypolipidemic Agents - therapeutic use | Practice Guidelines as Topic
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9. Full Text Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition
by Grundy, Scott M and Brewer Jr, H Bryan and Cleeman, James I and Smith Jr, Sidney C and Lenfant, Claude and Natl Heart Lung Blood I Amer Heart and National Heart, Lung, and Blood Institute and American Heart Association
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1524-4636, 02/2004, Volume 24, Issue 2, pp. e13 - 18
metabolic syndrome | DIAGNOSIS | INSULIN-RESISTANCE | DISEASE | PERIPHERAL VASCULAR DISEASE | diabetes mellitus | cardiovascular diseases | HEMATOLOGY | obesity | AHA Scientific Statements | American Heart Association | National Institutes of Health (U.S.) | Metabolic Syndrome - classification | World Health Organization | Metabolic Syndrome - diagnosis | United States | Humans | Metabolic Syndrome - pathology | Metabolic Syndrome - complications
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10. Full Text Cholesterol efflux and atheroprotection: Advancing the concept of reverse cholesterol transport
by Rosenson, Robert S and Brewer, H. Bryan and Davidson, W. Sean and Fayad, Zahi A and Fuster, Valentin and Goldstein, James and Hellerstein, Marc and Jiang, Xian-Cheng and Phillips, Michael C and Rader, Daniel J and Remaley, Alan T and Rothblat, George H and Tall, Alan R and Yvan-Charvet, Laurent
Circulation, ISSN 0009-7322, 04/2012, Volume 125, Issue 15, pp. 1905 - 1919
atherosclerosis | apolipoproteins | cardiovascular diseases | imaging | lipoproteins | CARDIAC & CARDIOVASCULAR SYSTEMS | ESTER TRANSFER PROTEIN | RECEPTOR CLASS-B | HEPATIC LIPASE DEFICIENCY | PRE-BETA-HDL | RANDOMIZED CONTROLLED-TRIAL | HIGH-DENSITY-LIPOPROTEIN | SCAVENGER RECEPTOR | MARROW-DERIVED CELLS | PERIPHERAL VASCULAR DISEASE | PHOSPHOLIPID TRANSFER PROTEIN | APOLIPOPROTEIN-A-I | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Cholesterol Ester Transfer Proteins - physiology | Humans | Cholesterol - metabolism | ATP-Binding Cassette Transporters - physiology | Lipoproteins, HDL - physiology | Scavenger Receptors, Class B - physiology | Macrophages - metabolism | Animals | Biological Transport | Phospholipid Transfer Proteins - physiology | Lipoproteins, HDL - chemistry | Models, Animal | Lipoproteins, HDL - analysis | Diffusion | Atherosclerosis - prevention & control | Measurement | Blood cholesterol | Cardiac patients | Causes of | Research | Cardiovascular diseases | Health aspects | Protein binding | cardiovascular disease | High density lipoprotein | reverse cholesterol transport | vascular imaging | cholesterol efflux
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11. Full Text Cholesteryl Ester Transfer Protein: A Novel Target for Raising HDL and Inhibiting Atherosclerosis
by Barter, Philip J and Brewer, H Bryan and Chapman, M John and Hennekens, Charles H and Rader, Daniel J and Tall, Alan R
Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association, ISSN 1079-5642, 02/2003, Volume 23, Issue 2, pp. 160 - 167
ABSTRACT—Cholesteryl ester transfer protein (CETP) promotes the transfer of cholesteryl esters from antiatherogenic HDLs to proatherogenic apolipoprotein B... 
HDL | Genetic CETP deficiency | LDL | Reverse cholesterol transport | reverse cholesterol transport | MYOCARDIAL-INFARCTION | CORONARY HEART-DISEASE | genetic CETP deficiency | DEFICIENCY | PLASMA | STANISLAS-COHORT | TAQIB POLYMORPHISM | PERIPHERAL VASCULAR DISEASE | CETP GENE | HEMATOLOGY | HIGH-DENSITY-LIPOPROTEINS | APOLIPOPROTEIN-A-I | TRANSGENIC MICE | Arteriosclerosis - etiology | Carrier Proteins - physiology | Cholesterol Esters - metabolism | Lipid Metabolism, Inborn Errors - genetics | Lipid Metabolism, Inborn Errors - blood | Humans | Carrier Proteins - antagonists & inhibitors | Glycoproteins | Lipoproteins - blood | Cholesterol Esters - blood | Carrier Proteins - genetics | Arteriosclerosis - prevention & control | Animals | Confounding Factors (Epidemiology) | Lipoproteins - metabolism | Cholesterol, HDL - blood | Sulfhydryl Compounds - therapeutic use | Lipid Metabolism, Inborn Errors - complications | Apolipoproteins - physiology | Arteriosclerosis - blood | Cholesterol Ester Transfer Proteins
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12. Full Text benefit-risk assessment of Rosuvastatin 10 to 40 milligrams
by Brewer, H.Bryan
The American Journal of Cardiology, ISSN 0002-9149, 2003, Volume 92, Issue 4, pp. 23 - 29
The aim of this article is to examine the benefit-risk profile of rosuvastatin at doses of 10 to 40 mg. In dyslipidemic patients, rosuvastatin produced... 
DENSITY-LIPOPROTEIN CHOLESTEROL | CARDIAC & CARDIOVASCULAR SYSTEMS | REDUCTASE INHIBITOR | PHARMACOKINETICS | EFFICACY | SAFETY | DOUBLE-BLIND | PRAVASTATIN | SIMVASTATIN | HYPERCHOLESTEROLEMIC PATIENTS | ATORVASTATIN | Pyrimidines | Risk Assessment | Sulfonamides | Humans | Hyperlipidemias - drug therapy | Cholesterol, HDL - blood | Rosuvastatin Calcium | Cholesterol, LDL - blood | Clinical Trials as Topic | Fluorobenzenes - administration & dosage | Safety
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13. Full Text A First-in-Man, Randomized, Placebo-Controlled Study to Evaluate the Safety and Feasibility of Autologous Delipidated High-Density Lipoprotein Plasma Infusions in Patients With Acute Coronary Syndrome
by Waksman, Ron, MD and Torguson, Rebecca, MPH and Kent, Kenneth M., MD, PhD and Pichard, Augusto D., MD and Suddath, William O., MD and Satler, Lowell F., MD and Martin, Brenda D., RN and Perlman, Timothy J., BSME and Maltais, Jo-Ann B., PhD and Weissman, Neil J., MD and Fitzgerald, Peter J., MD and Brewer, H. Bryan, MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2010, Volume 55, Issue 24, pp. 2727 - 2735
Objectives This study aimed to determine whether serial autologous infusions of selective high-density lipoprotein (HDL) delipidated plasma are feasible and... 
Cardiovascular | Internal Medicine | atheroma volume regression | acute coronary syndrome | HDL delipidation | CONTROLLED-TRIAL | CARDIAC & CARDIOVASCULAR SYSTEMS | EVENTS | MYOCARDIAL-INFARCTION | ATHEROSCLEROSIS | EFFLUX | DISEASE |