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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2018, Volume 26, Issue 14, pp. 3967 - 3974
The synthesis, ligand binding study and Elevated Plus Maze test (EPM) of a series of pyrazolo[4,3- ]quinolin-3-ones (PQs) are reported. Multistep synthesis of... 
Benzodiazepine binding | Pyrazoloquinolinones | GABAA receptor | Elevated plus maze | GABA | receptor
Journal Article
ISSN 2040-2503, 4/2014, Volume 5, Issue 5, pp. 622 - 631
Five carbonate derivatives of 5′- O -2′,3′-dideoxyinosine (DDI, 1 ) have been synthesized by combination with aliphatic alcohols, with their in vitro anti-HIV... 
Journal Article
Journal of Chemical Information and Modeling, ISSN 1549-9596, 01/2011, Volume 51, Issue 1, p. 130
The binding of several classes of nonnucleoside reverse transcriptase inhibitors (NNRTIs) to wild-type (wtRT) and K103N mutant (mRT) human immunodeficiency... 
Drugs | Molecules | Hydrogen bonds | Correlation analysis | Human immunodeficiency virus--HIV | Mutation | Binding sites
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2018, Volume 26, Issue 14, p. 3967
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.bmc.2018.06.021 The... 
Analysis | GABA | Antianxiety agents | Benzodiazepines
Journal Article
Journal Article
Journal of Chromatography A, ISSN 0021-9673, 2011, Volume 1218, Issue 18, pp. 2540 - 2545
This work studies the stability of three new anti-HIV agents which were obtained by the association of zidovudine (AZT) with different amino acids, such as... 
Zidovudine derivatives | Stability-indicating HPLC methods | Gastric and intestinal matrices | Micellar liquid chromatography | CHEMISTRY, ANALYTICAL | HUMAN SERUM-ALBUMIN | BIOCHEMICAL RESEARCH METHODS | MYOPATHY | 3-AZIDO-3-DEOXYTHYMIDINE | NUCLEOSIDE | IN-VITRO | AZT DERIVATIVES | PRODRUGS | AMINO-ACID DERIVATIVES | INHIBITORS | BINDING
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2012, Volume 58, pp. 485 - 492
A series of novel 4,6-diarylpyrimidines (4,6-DAPY) and diarylbenzenes (DABE) compounds were synthesized and evaluated as inhibitors of human immunodeficiency... 
HIV-1 | 4,6-Diarylpyrimidines | SAR | Molecular modeling | NNRTIs | Diarylbenzenes | DAPY ANALOGS | CHEMISTRY, MEDICINAL | COLORIMETRIC ASSAY | DRUG CANDIDATES | DISCOVERY | POTENT | EVOLUTION | Anti-HIV Agents - pharmacology | Benzene Derivatives - chemical synthesis | Pyrimidines - chemical synthesis | Antineoplastic Agents - chemical synthesis | HIV Reverse Transcriptase - antagonists & inhibitors | HIV-2 - enzymology | Humans | Reverse Transcriptase Inhibitors - pharmacology | Crystallography, X-Ray | HIV Reverse Transcriptase - genetics | Structure-Activity Relationship | Anti-HIV Agents - chemical synthesis | Pyrimidines - chemistry | Reverse Transcriptase Inhibitors - chemistry | Dose-Response Relationship, Drug | Reverse Transcriptase Inhibitors - chemical synthesis | HIV-2 - genetics | Antineoplastic Agents - pharmacology | Molecular Structure | Tumor Cells, Cultured | Benzene Derivatives - pharmacology | Cell Survival - drug effects | HIV-1 - drug effects | Models, Molecular | Pyrimidines - pharmacology | Antineoplastic Agents - chemistry | HIV-1 - genetics | HIV-2 - drug effects | HIV Reverse Transcriptase - metabolism | Anti-HIV Agents - chemistry | HIV-1 - enzymology | Benzene Derivatives - chemistry | Drug Screening Assays, Antitumor | DNA polymerases | Antiviral agents | Reverse transcriptase inhibitors | HIV (Viruses) | Analysis | Anti-HIV agents
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 12/2012, Volume 47, Issue 5, pp. 965 - 978
Journal Article
Scientia Pharmaceutica, ISSN 0036-8709, 2011, Volume 79, Issue 3, pp. 479 - 491
As part as of the preformulation studies of new 5'-OH derivatives of zidovudine, compounds 2-6, their acid dissociation constants, Differential Scanning... 
AZT derivatives | Aqueous stability | X-ray powder diffractometry | DSC and TG | Acid dissociation constants | X-Ray Powder Diffractometry
Journal Article
MedChemComm, ISSN 2040-2503, 2014, Volume 5, Issue 5, pp. 622 - 631
Five carbonate derivatives of 5′-O-2′,3′-dideoxyinosine (DDI, 1) have been synthesized by combination with aliphatic alcohols, with their in vitro anti-HIV... 
Journal Article