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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2017, Volume 114, Issue 39, p. E8224
Rab GTPases are switched from their GDP-bound inactive conformation to a GTP-bound active state by guanine nucleotide exchange factors (GEFs). The first... 
CRISPR | Yeast | Stability | Homology | Genomes | Glucose | Adipocytes | Chaperones | Exocytosis | Insulin | Cells | Genetic screening | Defects | Molecules | Restoration | Guanine nucleotide exchange factor | Conformation | Guanosinetriphosphatase
Journal Article
Journal Article
Cell, ISSN 0092-8674, 03/2019, Volume 177, Issue 1, pp. 200 - 220
Aging negatively impacts vitality and health. Many genetic pathways that regulate aging were discovered in invertebrates. However, the genetics of aging is... 
ALZHEIMER-DISEASE | STEM-CELLS | OXIDATIVE STRESS | ENERGY-EXPENDITURE | HUMAN LONGEVITY | REGULATES LIFE-SPAN | BIOCHEMISTRY & MOLECULAR BIOLOGY | SENESCENT CELLS | NOTHOBRANCHIUS-FURZERI | DIETARY RESTRICTION | GENOME-WIDE ASSOCIATION | CELL BIOLOGY
Journal Article
Developmental Cell, ISSN 1534-5807, 08/2019, Volume 50, Issue 4, pp. 436 - 446.e5
Multimeric adaptors are broadly involved in vesicle-mediated membrane trafficking. AP2 adaptor, in particular, plays a central role in clathrin-mediated... 
CRISPR screen | AP2 adaptor | adaptor complex | membrane trafficking | AP1 adaptor | clathrin-mediated endocytosis | REQUIREMENTS | RECRUITMENT | PROTEIN | RECOGNITION | VESICLES | SIGNALS | AP-2 | MECHANISMS | DEVELOPMENTAL BIOLOGY | GLUT4 | BINDING | CELL BIOLOGY | Medical colleges | Clathrin | Behavior genetics | Developmental biology | Genomics | Skin diseases | Skin | Kidney diseases | Genetic screening | Protein binding
Journal Article
01/2017, ISBN 9780355231014
The human oral microbiome is formed early in development. Its composition is influenced by environmental factors including diet, substance use, oral health,... 
Genetics
Dissertation
01/2018, ISBN 9780438321045
A lack of training around religious and spiritual issues in formalized mental health professional programs has placed the responsibility to ensure clinicians... 
Spirituality | Counseling Psychology
Dissertation
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