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by Bateman, Alex and Martin, Maria Jesus and O'Donovan, Claire and Magrane, Michele and Alpi, Emanuele and Antunes, Ricardo and Bely, Benoit and Bingley, Mark and Bonilla, Carlos and Britto, Ramona and Bursteinas, Borisas and Bye-AJee, Hema and Cowley, Andrew and Da Silva, Alan and De Giorgi, Maurizio and Dogan, Tunca and Fazzini, Francesco and Castro, Leyla Garcia and Figueira, Luis and Garmiri, Penelope and Georghiou, George and Gonzalez, Daniel and Hatton-Ellis, Emma and Li, Weizhong and Liu, Wudong and Lopez, Rodrigo and Luo, Jie and Lussi, Yvonne and MacDougall, Alistair and Nightingale, Andrew and Palka, Barbara and Pichler, Klemens and Poggioli, Diego and Pundir, Sangya and Pureza, Luis and Qi, Guoying and Rosanoff, Steven and Saidi, Rabie and Sawford, Tony and Shypitsyna, Aleksandra and Speretta, Elena and Turner, Edward and Tyagi, Nidhi and Volynkin, Vladimir and Wardell, Tony and Warner, Kate and Watkins, Xavier and Zaru, Rossana and Zellner, Hermann and Xenarios, Ioannis and Bougueleret, Lydie and Bridge, Alan and Poux, Sylvain and Redaschi, Nicole and Aimo, Lucila and ArgoudPuy, Ghislaine and Auchincloss, Andrea and Axelsen, Kristian and Bansal, Parit and Baratin, Delphine and Blatter, Marie-Claude and Boeckmann, Brigitte and Bolleman, Jerven and Boutet, Emmanuel and Breuza, Lionel and Casal-Casas, Cristina and De Castro, Edouard and Coudert, Elisabeth and Cuche, Beatrice and Doche, Mikael and Dornevil, Dolnide and Duvaud, Severine and Estreicher, Anne and Famiglietti, Livia and Feuermann, Marc and Gasteiger, Elisabeth and Gehant, Sebastien and Gerritsen, Vivienne and Gos, Arnaud and Gruaz-Gumowski, Nadine and Hinz, Ursula and Hulo, Chantal and Jungo, Florence and Keller, Guillaume and Lara, Vicente and Lemercier, Philippe and Lieberherr, Damien and Lombardot, Thierry and Martin, Xavier and Masson, Patrick and Morgat, Anne and Neto, Teresa and Nouspikel, Nevila and Paesano, Salvo and Pedruzzi, Ivo and Pilbout, Sandrine and Pozzato, Monica and Pruess, Manuela and Rivoire, Catherine and Roechert, Bernd and ... and UniProt Consortium and The UniProt Consortium
Nucleic Acids Research, ISSN 0305-1048, 01/2017, Volume 45, Issue 1, pp. D158 - D169
The UniProt knowledgebase is a large resource of protein sequences and associated detailed annotation. The database contains over 60 million sequences, of... 
DISEASES | DATABASE | CLUSTERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GUIDELINES | SEQUENCE VARIANTS | CLASSIFICATION | CHROMOSOMES | TUBULIN | RESOURCE | GLUTAMYLATION
Journal Article
by Bateman, Alex and Martin, Maria Jesus and O'Donovan, Claire and Magrane, Michele and Apweiler, Rolf and Alpi, Emanuele and Antunes, Ricardo and Arganiska, Joanna and Bely, Benoit and Bingley, Mark and Bonilla, Carlos and Britto, Ramona and Bursteinas, Borisas and Chavali, Gayatri and Cibrian-Uhalte, Elena and Da Silva, Alan and De Giorgi, Maurizio and Dogan, Tunca and Fazzini, Francesco and Gane, Paul and Castro, Leyla Garcia and Garmiri, Penelope and Hatton-Ellis, Emma and Hieta, Reija and Huntley, Rachael and Legge, Duncan and Liu, Wudong and Luo, Jie and MacDougall, Alistair and Mutowo, Prudence and Nightingale, Andrew and Orchard, Sandra and Pichler, Klemens and Poggioli, Diego and Pundir, Sangya and Pureza, Luis and Qi, Guoying and Rosanoff, Steven and Saidi, Rabie and Sawford, Tony and Shypitsyna, Aleksandra and Turner, Edward and Volynkin, Vladimir and Wardell, Tony and Watkins, Xavier and Zellner, Hermann and Cowley, Andrew and Figueira, Luis and Li, Weizhong and McWilliam, Hamish and Lopez, Rodrigo and Xenarios, Ioannis and Bougueleret, Lydie and Bridge, Alan and Poux, Sylvain and Redaschi, Nicole and Aimo, Lucila and Argoud-Puy, Ghislaine and Auchincloss, Andrea and Axelsen, Kristian and Bansal, Parit and Baratin, Delphine and Blatter, Marie-Claude and Boeckmann, Brigitte and Bolleman, Jerven and Boutet, Emmanuel and Breuza, Lionel and Casal-Casas, Cristina and De Castro, Edouard and Coudert, Elisabeth and Cuche, Beatrice and Doche, Mikael and Dornevil, Dolnide and Duvaud, Severine and Estreicher, Anne and Famiglietti, Livia and Feuermann, Marc and Gasteiger, Elisabeth and Gehant, Sebastien and Gerritsen, Vivienne and Gos, Arnaud and Gruaz-Gumowski, Nadine and Hinz, Ursula and Hulo, Chantal and Jungo, Florence and Keller, Guillaume and Lara, Vicente and Lemercier, Philippe and Lieberherr, Damien and Lombardot, Thierry and Martin, Xavier and Masson, Patrick and Morgat, Anne and Neto, Teresa and Nouspikel, Nevila and Paesano, Salvo and Pedruzzi, Ivo and Pilbout, Sandrine and Pozzato, Monica and Pruess, Manuela and ... and UniProt Consortium and The UniProt Consortium
Nucleic Acids Research, ISSN 0305-1048, 01/2015, Volume 43, Issue 1, pp. D204 - D212
UniProt is an important collection of protein sequences and their annotations, which has doubled in size to 80 million sequences during the past year. This... 
DATABASE | ANNOTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | Sequence Analysis, Protein | Proteome | Databases, Protein | Molecular Sequence Annotation | Database Issue
Journal Article
by Apweiler, Rolf and Bateman, Alex and Martin, Maria Jesus and O'Donovan, Claire and Magrane, Michele and Alam-Faruque, Yasmin and Alpi, Emanuele and Antunes, Ricardo and Arganiska, Joanna and Casanova, Elisabet Barrera and Bely, Benoit and Bingley, Mark and Bonilla, Carlos and Britto, Ramona and Bursteinas, Borisas and Chan, Wei Mun and Chavali, Gayatri and Cibrian-Uhalte, Elena and Da Silva, Alan and De Giorgi, Maurizio and Fazzini, Francesco and Gane, Paul and Castro, Leyla Garcia and Garmiri, Penelope and Hatton-Ellis, Emma and Hieta, Reija and Huntley, Rachael and Legge, Duncan and Liu, Wudong and Luo, Jie and MacDougall, Alistair and Mutowo, Prudence and Nightingale, Andrew and Orchard, Sandra and Pichler, Klemens and Poggioli, Diego and Pundir, Sangya and Pureza, Luis and Qi, Guoying and Rosanoff, Steven and Sawford, Tony and Shypitsyna, Aleksandra and Turner, Edward and Volynkin, Vladimir and Wardell, Tony and Watkins, Xavier and Corbett, Matt and Donnelly, Mike and Van Rensburg, Pieter and Goujon, Mickael and McWilliam, Hamish and Lopez, Rodrigo and Xenarios, Ioannis and Bougueleret, Lydie and Bridge, Alan and Poux, Sylvain and Redaschi, Nicole and Aimo, Lucila and Auchincloss, Andrea and Axelsen, Kristian and Bansal, Parit and Baratin, Delphine and Binz, Pierre-Alain and Blatter, Marie-Claude and Boeckmann, Brigitte and Bolleman, Jerven and Boutet, Emmanuel and Breuza, Lionel and Casal-Casas, Cristina and De Castro, Edouard and Cerutti, Lorenzo and Coudert, Elisabeth and Cuche, Beatrice and Doche, Mikael and Dornevil, Dolnide and Duvaud, Severine and Estreicher, Anne and Famiglietti, Livia and Feuermann, Marc and Gasteiger, Elisabeth and Gehant, Sebastien and Gerritsen, Vivienne and Gos, Arnaud and Gruaz-Gumowski, Nadine and Hinz, Ursula and Hulo, Chantal and James, Janet and Jungo, Florence and Keller, Guillaume and Lara, Vicente and Lemercier, Philippe and Lew, Jocelyne and Lieberherr, Damien and Lombardot, Thierry and Martin, Xavier and Masson, Patrick and Morgat, Anne and Neto, Teresa and Paesano, Salvo and Pedruzzi, Ivo and ... and UniProt Consortium
Nucleic Acids Research, ISSN 0305-1048, 01/2014, Volume 42, Issue 1, pp. D191 - D198
The mission of the Universal Protein Resource (UniProt) (http://www.uniprot.org) is to provide the scientific community with a comprehensive, high-quality and... 
REPRESENTATION | ONTOLOGY | GENOME DATABASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FAMILY
Journal Article
by Apweiler, Rolf and Martin, Maria Jesus and O'Donovan, Claire and Magrane, Michele and Alam-Faruque, Yasmin and Alpi, Emanuela and Antunes, Ricardo and Arganiska, Joanna and Casanova, Elisabet Barrera and Bely, Benoit and Bingley, Mark and Bonilla, Carlos and Britto, Ramona and Bursteinas, Borisas and Chan, Wei Mun and Chavali, Gayatri and Cibrian-Uhalte, Elena and Da Silva, Alan and De Giorgi, Maurizio and Dimmer, Emily and Fazzini, Francesco and Gane, Paul and Fedotov, Alexander and Castro, Leyla Garcia and Garmiri, Penelope and Hatton-Ellis, Emma and Hieta, Reija and Huntley, Rachael and Jacobsen, Julius and Jones, Rachel and Legge, Duncan and Liu, Wudong and Luo, Jie and MacDougall, Alistair and Mutowo, Prudence and Nightingale, Andrew and Orchard, Sandra and Patient, Samuel and Pichler, Klemens and Poggioli, Diego and Pundir, Sangya and Pureza, Luis and Qi, Guoying and Rosanoff, Steven and Sawford, Tony and Sehra, Harminder and Turner, Edward and Volynkin, Vladimir and Wardell, Tony and Watkins, Xavier and Zellner, Hermann and Corbett, Matt and Donnelly, Mike and Van Rensburg, Pieter and Goujon, Mickael and McWilliam, Hamish and Lopez, Rodrigo and Xenarios, Ioannis and Bougueleret, Lydie and Bridge, Alan and Poux, Sylvain and Redaschi, Nicole and Auchincloss, Andrea and Axelsen, Kristian and Bansal, Parit and Baratin, Delphine and Binz, Pierre-Alain and Blatter, Marie-Claude and Boeckmann, Brigitte and Bolleman, Jerven and Boutet, Emmanuel and Breuza, Lionel and De Castro, Edouard and Cerutti, Lorenzo and Coudert, Elisabeth and Cuche, Beatrice and Doche, Mikael and Dornevil, Dolnide and Duvaud, Severine and Estreicher, Anne and Famiglietti, Livia and Feuermann, Marc and Gasteiger, Elisabeth and Gehant, Sebastien and Gerritsen, Vivienne and Gos, Arnaud and Gruaz-Gumowski, Nadine and Hinz, Ursula and Hulo, Chantal and James, Janet and Jungo, Florence and Keller, Guillaume and Lara, Vicente and Lemercier, Philippe and Lew, Jocelyne and Lieberherr, Damien and Martin, Xavier and Masson, Patrick and Morgat, Anne and Neto, Teresa and ... and UniProt Consortium and The UniProt Consortium
Nucleic Acids Research, ISSN 0305-1048, 01/2013, Volume 41, Issue 1, pp. D43 - D47
The mission of the Universal Protein Resource (UniProt) (http://www.uniprot.org) is to support biological research by providing a freely accessible, stable,... 
DATABASE | ANNOTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | Sequence Analysis, Protein | Internet | Databases, Protein | Molecular Sequence Annotation
Journal Article
Oncogene, ISSN 0950-9232, 10/2005, Volume 24, Issue 47, pp. 7073 - 7083
Astrocytoma is the most common type of brain cancer constituting more than half of all brain tumors. With an aim to identify markers describing astrocytoma... 
Glioma | ASCL1 | Microarray | Notch signaling | Glioblastoma multiforme | Astrocytoma | glioblastoma multiforme | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROENDOCRINE DIFFERENTIATION | HUMAN GLIOMA | MICROARRAY ANALYSIS | BRAIN-TUMORS | CELL BIOLOGY | microarray | astrocytoma | ONCOLOGY | HUMAN GLIAL TUMORS | GENETICS & HEREDITY | GENE-EXPRESSION | glioma | CENTRAL-NERVOUS-SYSTEM | GROWTH-FACTOR | ACHAETE-SCUTE | Up-Regulation | Oligonucleotide Array Sequence Analysis | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Gene Expression Profiling | Helix-Loop-Helix Motifs | RNA, Neoplasm - metabolism | Brain Neoplasms - metabolism | Brain - metabolism | DNA-Binding Proteins - metabolism | Astrocytoma - pathology | Receptors, Notch | Glioblastoma - genetics | Glioblastoma - metabolism | Membrane Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors | Astrocytoma - genetics | Astrocytoma - metabolism | Signal Transduction | Membrane Proteins - genetics | Brain Neoplasms - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Disease Progression | Transcription Factors - metabolism | Membrane Proteins - antagonists & inhibitors | Glioblastoma - pathology | Brain - pathology | RNA, Neoplasm - genetics
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2006, Volume 281, Issue 24, pp. 16207 - 16219
Activator protein 2 alpha ( AP-2 alpha) induces cytotoxicity by inducing cell cycle arrest and apoptosis. In this study we investigated the mechanism of... 
FACTOR AP-2 | SIGNAL-TRANSDUCTION | BREAST-CANCER CELLS | DNA-BINDING | PHOSPHATASE 2A | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYCLE ARREST | HUMAN-MELANOMA | KINASE-C | UP-REGULATION | TUMOR-GROWTH
Journal Article
Journal of Inorganic Biochemistry, ISSN 0162-0134, 2010, Volume 104, Issue 2, pp. 93 - 104
Journal Article
Database, ISSN 1758-0463, 01/2016, Volume 2016, pp. 1 - 9
Advances in high-throughput sequencing have led to an unprecedented growth in genome sequences being submitted to biological databases. In particular, the... 
MATHEMATICAL & COMPUTATIONAL BIOLOGY | Sequence Analysis, Protein - methods | Bacteria - metabolism | Proteome - genetics | Databases, Protein | Bacterial Proteins - genetics | Bacterial Proteins - metabolism | Molecular Sequence Annotation - methods | Bacteria - genetics | Proteome - metabolism
Journal Article
by Zaru, Rossana and Magrane, Michele and O'Donovan, Claire and Bateman, Alex and Martin, Maria Jesus and Alpi, Emanuele and Antunes, Ricardo and Bely, Benoit and Bingley, Mark and Bonilla, Carlos and Britto, Ramona and Bursteinas, Borisas and Bye-A-Jee, Hema and Cowley, Andrew and Da Silva, Alan and De Giorgi, Maurizio and Dogan, Tunca and Fazzini, Francesco and Castro, Leyla Garcia and Figueira, Luis and Garmiri, Penelope and Georghiou, George and Gonzalez, Daniel and Hatton-Ellis, Emma and Li, Weizhong and Liu, Wudong and Lopez, Rodrigo and Luo, Jie and Lussi, Yvonne and MacDougall, Alistair and Nightingale, Andrew and Palka, Barbara and Pichler, Klemens and Poggioli, Diego and Pundir, Sangya and Pureza, Luis and Qi, Guoying and Rosanoff, Steven and Saidi, Rabie and Sawford, Tony and Shypitsyna, Aleksandra and Speretta, Elena and Turner, Edward and Tyagi, Nidhi and Volynkin, Vladimir and Wardell, Tony and Warner, Kate and Watkins, Xavier and Zellner, Hermann and Xenarios, Ioannis and Bougueleret, Lydie and Bridge, Alan and Poux, Sylvain and Redaschi, Nicole and Aimo, Lucila and Argoud-Puy, Ghislaine and Auchincloss, Andrea and Axelsen, Kristian and Bansal, Parit and Baratin, Delphine and Blatter, Marie-Claude and Boeckmann, Brigitte and Bolleman, Jerven and Boutet, Emmanuel and Breuza, Lionel and Casal-Casas, Cristina and De Castro, Edouard and Coudert, Elisabeth and Cuche, Beatrice and Doche, Mikael and Dornevil, Dolnide and Duvaud, Severine and Estreicher, Anne and Famiglietti, Livia and Feuermann, Marc and Gasteiger, Elisabeth and Gehant, Sebastien and Gerritsen, Vivienne and Gos, Arnaud and Gruaz-Gumowski, Nadine and Hinz, Ursula and Hulo, Chantal and Jungo, Florence and Keller, Guillaume and Lara, Vicente and Lemercier, Philippe and Lieberherr, Damien and Lombardot, Thierry and Martin, Xavier and Masson, Patrick and Morgat, Anne and Neto, Teresa and Nouspikel, Nevila and Paesano, Salvo and Pedruzzi, Ivo and Pilbout, Sandrine and Pozzato, Monica and Pruess, Manuela and Rivoire, Catherine and Roechert, Bernd and ... and UniProt Consortium and the UniProt Consortium
Biochemical Journal, ISSN 0264-6021, 02/2017, Volume 474, Issue 4, pp. 493 - 515
Protein kinases form one of the largest protein families and are found in all species, from viruses to humans. They catalyze the reversible phosphorylation of... 
KINASE FAMILY | DOMAIN | PHOSPHORYLATION | ANNOTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | TRANSDUCTION | PROTEIN FAMILIES DATABASE | MECHANISMS | IDENTIFICATION | BINDING | Protein Kinases - metabolism | Amino Acid Sequence | User-Computer Interface | Protein Kinases - genetics | Proteome - genetics | Signal Transduction |