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ORGANIC LETTERS, ISSN 1523-7060, 04/2019, Volume 21, Issue 7, pp. 2482 - 2487
Palladium catalyzed hydrodefluorination was developed for fine-tuning the properties of fluoro-(hetero)aromatic compounds. The robust reaction can be set up in... 
MEDICINAL CHEMISTRY | FLUOROARENES | FACILE ACCESS | HYDROGEN-TRANSFER | FLUORINE SCAN | ELECTROCHEMICAL HYDRODEFLUORINATION | ARYL HALIDES | CHEMISTRY, ORGANIC | C-F | F BOND ACTIVATION | NUCLEOPHILIC AROMATIC-SUBSTITUTION
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2017, Volume 60, Issue 15, pp. 6649 - 6663
Recent data demonstrated that activation of the muscarinic M1 receptor by a subtype-selective positive allosteric modulator (PAM) contributes to the... 
Index Medicus
Journal Article
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Organic Process Research & Development, ISSN 1083-6160, 02/2016, Volume 20, Issue 2, pp. 233 - 241
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ISSN 0960-894X, 01/2016, Volume 26, Issue 2, pp. 650 - 655
Selective activation of the M-1 receptor via a positive allosteric modulator (PAM) is a new approach for the treatment of the cognitive impairments associated... 
ACTIVATION | CHEMISTRY, MEDICINAL | SERIES | ALZHEIMERS-DISEASE | CHEMISTRY, ORGANIC | SCHIZOPHRENIA | XANOMELINE | Azaindole amide | AGONISTS | DISCOVERY | M-1 selective activator | MUSCARINIC ACETYLCHOLINE-RECEPTOR | M-1 positive allosteric modulator (PAM) | Intra-molecular hydrogen bond (IMHB) | IN-VIVO | CENTRAL-NERVOUS-SYSTEM
Journal Article
11/2010, Topics in Medicinal Chemistry Ser., ISBN 364209354X, Volume 2
Annotation This volume will first review existing cholinesterase inhibitors prescribed for Alzheimers disease (AD) patients followed by some target mechanisms... 
Alzheimer's Disease | Medical
Web Resource
11/2010, Topics in Medicinal Chemistry Ser., ISBN 364209354X, Volume 2
Annotation This volume will first review existing cholinesterase inhibitors prescribed for Alzheimers disease (AD) patients followed by some target mechanisms... 
Alzheimer's Disease | Medical
Web Resource
Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2018, Volume 61, Issue 7, pp. 3008 - 3026
Monoacylglycerol lipase (MAGL) inhibition provides a potential treatment approach to neuroinflammation through modulation of both the endocannabinoid pathway... 
SERINE HYDROLASES | SYSTEM | CHEMISTRY, MEDICINAL | MULTIPLE-SCLEROSIS | METABOLISM | ALIGNMENT | MONOGLYCERIDE LIPASE | MOUSE MODEL | DISEASE | OPTIMIZATION | TOOL
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2018, Volume 61, Issue 8, pp. 3296 - 3308
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2012, Volume 55, Issue 21, pp. 9224 - 9239
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2015, Volume 58, Issue 6, pp. 2678 - 2702
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2015, Volume 58, Issue 7, pp. 3223 - 3252
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