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PLoS pathogens, ISSN 1553-7374, 02/2012, Volume 8, Issue 2, pp. e1002507 - e1002507
Survival within macrophages is a central feature of Mycobacterium tuberculosis pathogenesis. Despite significant advances in identifying new immunological... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Phagosomes - microbiology | Cell Line | Salmonella typhimurium - pathogenicity | Homeodomain Proteins - metabolism | Humans | Phagosomes - metabolism | Shigella flexneri - pathogenicity | Mycobacterium tuberculosis - immunology | Mycobacterium Infections - metabolism | Mycobacterium marinum - pathogenicity | Phagosomes - pathology | Mycobacterium Infections - immunology | Mycobacterium tuberculosis - pathogenicity | Macrophages - metabolism | Immune Evasion | Mycobacterium marinum - immunology | Cell Death | Fluorescence Resonance Energy Transfer - methods | Mycobacterium Infections - pathology | Mycobacterium marinum - metabolism | Mycobacterium tuberculosis - metabolism | Macrophages - microbiology | Mycobacterium tuberculosis | Cell death | Phagosomes | Physiological aspects | Development and progression | Research | Health aspects | Proteins | Signal transduction | Tuberculosis | Algorithms | Toxicity | Software | Infections | Experiments | Apoptosis | Index Medicus | Mycobacterium marinum | Biochemistry, Molecular Biology | Shigella flexneri | Mycobacterium Infections | Macrophages | Cellular Biology | Salmonella typhimurium | Life Sciences | Homeodomain Proteins | Fluorescence Resonance Energy Transfer | Biomolecules | Cell Behavior
Journal Article
Autophagy, ISSN 1554-8635, 10/2014, Volume 8, Issue 9, pp. 1357 - 1370
..., 1 Valérie Gafa, 2 Roxane Simeone, 4 Giovanni Delogu, 3 Mauro Piacentini, 1,5 Roland Brosch, 4 Gian Maria Fimia 1, * and e liana M. c occia 2, * 1 Department... 
vaccine | autophagy | dendritic cells | Mycobacterium tuberculosis | BCG | RD1 region | ESX1/type VII secretion system | Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Dendritic cells | Vaccine | Autophagy | Rd1 region | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Biomarkers - metabolism | Th1 Cells - drug effects | Humans | Phagosomes - metabolism | Cells, Cultured | Mycobacterium tuberculosis - ultrastructure | Dendritic Cells - pathology | Tuberculosis - microbiology | Th1 Cells - immunology | Mycobacterium tuberculosis - drug effects | Sirolimus - pharmacology | Autophagy - drug effects | Tuberculosis - immunology | Mycobacterium bovis - drug effects | Bacterial Secretion Systems - drug effects | Cell Differentiation - drug effects | Dendritic Cells - ultrastructure | Mycobacterium tuberculosis - physiology | Dendritic Cells - microbiology | Dendritic Cells - drug effects | Phagosomes - ultrastructure | Mycobacterium bovis - physiology | Phagosomes - drug effects | Tuberculosis - pathology | Index Medicus | Dendritic Cells | Bacterial Secretion Systems | Sirolimus | Mycobacterium bovis | Phagosomes | Life Sciences | Tuberculosis | Th1 Cells | Biomarkers | Cell Differentiation | ESX1 | Basic Research Paper | type VII secretion system
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 03/2009, Volume 324, Issue 5928, pp. 801 - 804
New drugs are required to counter the tuberculosis (TB) pandemic. Here, we describe the synthesis and characterization of 1,3-benzothiazin-4-ones (BTZs), a new... 
Enzymes | Antibacterials | Tuberculosis | Mycobacterium tuberculosis | Cell walls | Antituberculars | Bacteria | Reports | Biochemistry | Enantiomers | Codons | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antitubercular Agents - chemical synthesis | Antitubercular Agents - chemistry | Thiazines - therapeutic use | Ethambutol - pharmacology | Drug Resistance, Bacterial | Molecular Sequence Data | Spiro Compounds - therapeutic use | Tuberculosis - microbiology | Mycobacterium tuberculosis - drug effects | Polysaccharides - biosynthesis | Microbial Sensitivity Tests | Racemases and Epimerases - metabolism | Enzyme Inhibitors - chemistry | Spiro Compounds - chemical synthesis | Tuberculosis - drug therapy | Arabinose - metabolism | Thiazines - pharmacology | Molecular Structure | Mycobacterium tuberculosis - metabolism | Spiro Compounds - chemistry | Antitubercular Agents - therapeutic use | Amino Acid Sequence | Genes, Bacterial | Antitubercular Agents - pharmacology | Enzyme Inhibitors - pharmacology | Racemases and Epimerases - antagonists & inhibitors | Enzyme Inhibitors - therapeutic use | Thiazines - chemical synthesis | Thiazines - chemistry | Mycobacterium - genetics | Mycobacterium - drug effects | Gene Expression Regulation, Bacterial - drug effects | Animals | Cell Wall - metabolism | Enzyme Inhibitors - cerebrospinal fluid | Mice | Mice, Inbred BALB C | Spiro Compounds - pharmacology | Mycobacterium tuberculosis - genetics | Antitubercular agents | Dosage and administration | Drug therapy | Genetics | Pharmacology | Chemical synthesis | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 07/2014, Volume 111, Issue 31, pp. 11491 - 11496
Although the bovine tuberculosis (TB) agent, Mycobacterium bovis, may infect humans and cause disease, long-term epidemiological data indicate that humans... 
Mycobacterium | Tuberculosis | Mycobacterium tuberculosis | Mycobacterium bovis | Secretion | Humans | Virulence | Alleles | Lipids | Genetic mutation | Evolution | Phylogeny | Zoonosis | Adaptation | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Conserved Sequence - genetics | Bacterial Proteins - genetics | Tuberculosis - microbiology | Antigens, Bacterial | Bacterial Proteins - secretion | Mutation - genetics | Mycobacterium - genetics | Biological Evolution | Host-Pathogen Interactions | Mycobacterium tuberculosis - pathogenicity | Animals | Tuberculosis - genetics | Virulence - genetics | Cattle | Gene Deletion | Polymorphism, Single Nucleotide - genetics | Mutagenesis, Insertional | Mycobacterium bovis - pathogenicity | Mycobacterium bovis - genetics | Mycobacterium tuberculosis - genetics | Tuberculosis in cattle | Microbiological research | Research | Natural history | Microbial mutation | Genetics | Mutation | Evolutionary biology | Index Medicus | Mycobacterium tuberculosis / pathogenicity | Tuberculosis / microbiology | Life Sciences | Bacterial Proteins / genetics | Conserved Sequence / genetics | Bacterial Proteins / metabolism | Virulence / genetics | Mycobacterium bovis / pathogenicity | Tuberculosis / genetics | Mycobacterium tuberculosis / genetics | Bacteriology | Mycobacterium bovis / genetics | Microbiology and Parasitology | Polymorphism, Single Nucleotide / genetics | Mutation / genetics | Mycobacterium / genetics | Biological Sciences | phylogeny | adaptation | evolution | zoonosis
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 03/2007, Volume 104, Issue 13, pp. 5596 - 5601
Journal Article