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Lancet, The, ISSN 0140-6736, 2009, Volume 374, Issue 9701, pp. 1617 - 1625
Journal Article
Lancet, The, ISSN 0140-6736, 2016, Volume 388, Issue 10044, pp. 565 - 575
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 5, pp. 1144 - 1152.e11
Background Signals emanating from the antigen T-cell receptor (TCR) are required for T-cell development and function. The T lymphocyte–specific protein... 
Allergy and Immunology | LCK, SRC tyrosine kinase | recurrent infections | CD4 | T-cell receptor signaling | autoinflammation | immunodeficiency | genetic defect | lymphopenia | ACTIVATION | COMPLEX | SRC tyrosine kinase | PROTEIN-TYROSINE KINASES | P56(LCK) | IMMUNOLOGY | MICE LACKING | SIGNAL-TRANSDUCTION | ALLERGY | LCK | MUTATION | DOCK8 DEFICIENCY | FYN | ANTIGEN RECEPTOR | Genetic Predisposition to Disease | T-Lymphocytopenia, Idiopathic CD4-Positive - diagnosis | Receptors, Antigen, T-Cell - metabolism | Genes, Recessive - genetics | Humans | Cells, Cultured | Child, Preschool | T-Lymphocytopenia, Idiopathic CD4-Positive - genetics | Mutation, Missense - genetics | Polymorphism, Genetic | CD4-Positive T-Lymphocytes - immunology | DNA Mutational Analysis | Pedigree | Immunologic Deficiency Syndromes - genetics | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - chemistry | Female | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - genetics | Calcium Signaling - genetics | France | Immunologic Deficiency Syndromes - diagnosis | Tyrosine | Antigens | T cells | Genes | Immunodeficiency | T cell receptors | Infections | Kinases | Viral infections | Immune system | Autoimmunity | Calcium mobilization | Phosphorylation | CD8 antigen | Recurrent infection | Inflammation | Lymphocytes T | Risk factors | CD4 antigen | Calcium signalling | T-cell receptor | Missense mutation | Lymphopenia | Lck protein | Respiratory tract diseases | Differentiation | Protein-tyrosine kinase | Age | uniparental disomy | Life Sciences | Biochemistry, Molecular Biology
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2008, Volume 118, Issue 9, pp. 3132 - 3142
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 5, pp. 1131 - 1141.e9
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 6, pp. 1354 - 1364.e6
Background Inflammatory bowel disease (IBD) is one of the most common chronic gastrointestinal diseases, but the underlying molecular mechanisms remain largely... 
Allergy and Immunology | Inflammatory bowel disease | immune deficiency | lymphocytes | RhoA kinase | cytoskeleton | gut organoid | cell homeostasis | tetratricopeptide repeat domain 7A deficiency | Duodenum | Inflammatory Bowel Diseases | Humans | Middle Aged | Child, Preschool | Infant | Male | rhoA GTP-Binding Protein | Pyloric Antrum | Mutation, Missense | Proteins | Young Adult | Alopecia | Lymphopenia | rho-Associated Kinases | Adolescent | Adult | Female | Colon | Child | cytoskeleton gut organoid | DENDRITIC CELLS | CROHNS-DISEASE | MECHANISMS | IMMUNOLOGY | PLASMA-MEMBRANE | PATHOGENESIS | GENE | ALLERGY | RHO GTPASES | FLAKY SKIN | TTC7A MUTATIONS | IMMUNODEFICIENCY | rhoA GTP-Binding Protein - immunology | Alopecia - immunology | Inflammatory Bowel Diseases - immunology | Lymphopenia - pathology | rho-Associated Kinases - antagonists & inhibitors | Alopecia - genetics | Inflammatory Bowel Diseases - pathology | Inflammatory Bowel Diseases - genetics | Colon - pathology | Pyloric Antrum - pathology | Proteins - immunology | Alopecia - pathology | Proteins - genetics | Duodenum - pathology | rho-Associated Kinases - immunology | Lymphopenia - immunology | Lymphopenia - genetics | Developmental biology | Gastrointestinal diseases | Stem cells | Immunodeficiency | Autoimmunity | Baldness | Analysis | Lymphocytopenia | Studies | Parenteral nutrition | Mutation | Patients | Age | Immune system | Apoptosis
Journal Article
The Lancet, ISSN 0140-6736, 03/2002, Volume 359, Issue 9308, pp. 753 - 759
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2010, Volume 120, Issue 6, pp. 2131 - 2143
Enteropathy-associated T cell lymphoma is a severe complication of celiac disease (CD). One mechanism suggested to underlie its development is chronic exposure... 
INTESTINAL INFLAMMATION | RHEUMATOID-ARTHRITIS | MEDICINE, RESEARCH & EXPERIMENTAL | MOLECULAR TARGETS | NATURAL-KILLER-CELLS | INTERLEUKIN-15 | BCL-X | RECEPTOR | REFRACTORY SPRUE | CD8(+) T-CELLS | TRANSGENIC MICE | Phosphorylation | Apoptosis - drug effects | Enterocytes - metabolism | Humans | Intestines - metabolism | Leukemia - metabolism | STAT3 Transcription Factor - pharmacology | Interleukin-15 - immunology | Intestines - immunology | Inflammation - complications | Signal Transduction - immunology | Inflammation - metabolism | Lymphocytes - immunology | Celiac Disease - immunology | Leukemia - complications | Celiac Disease - complications | Adult | Janus Kinase 3 - metabolism | Intestine, Small - immunology | STAT3 Transcription Factor - metabolism | Cytokines - immunology | Janus Kinase 3 - immunology | Lymphocytes - metabolism | Cytokines - metabolism | Inflammation - immunology | Protein Binding - immunology | Enterocytes - immunology | Interleukin-15 - pharmacology | Apoptosis - immunology | Signal Transduction - drug effects | Leukemia - immunology | Interleukin-15 - metabolism | Intestine, Small - metabolism | STAT3 Transcription Factor - immunology | Celiac Disease - metabolism | Cytokines - pharmacology | Care and treatment | Lymphocytes | Development and progression | Interleukin-15 | Inflammation | Non-Hodgkin's lymphomas | T cells | Properties | Health aspects
Journal Article