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Cell Reports, ISSN 2211-1247, 12/2018, Volume 25, Issue 12, pp. 3315 - 3328.e6
Mutations in genes essential for mitochondrial function have pleiotropic effects. The mechanisms underlying these traits yield insights into metabolic... 
adiposity | ISR | hypertrophic cardiomyopathy | mitochondrial dysfunction | deafness | pleiotropic | WARS2 | RESPIRATORY-CHAIN DEFICIENCY | HEARING-LOSS | HYPERTROPHIC CARDIOMYOPATHY | GENE | TRANSFER-RNA SYNTHETASE | LACTIC-ACIDOSIS | MUTATIONS | INDUCTION | MITOCHONDRIAL MYOPATHY | FGF21 | CELL BIOLOGY
Journal Article
Mammalian Genome, ISSN 0938-8990, 10/2012, Volume 23, Issue 9, pp. 632 - 640
Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the... 
Life Sciences | Anatomy | Zoology | Cell Biology | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EUROPHENOME | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | FUNCTIONAL ANNOTATION | EMPRESS | MICROSCOPY | GENOME | MORPHOLOGY | RESOURCE | Phenotype | Mice | Animals | Internationality | Mice, Mutant Strains | Indexing in process
Journal Article
Mammalian genome : official journal of the International Mammalian Genome Society, 2011, Volume 22, Issue 7-8, p. 361
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 08/2018, Volume 27, Issue R2, pp. R130 - R135
Abstract Over the past 25 years, human and mouse genetics research together has identified several hundred genes essential for mammalian hearing, leading to a... 
ENU MUTAGENESIS | HAIR-CELLS | SENSORINEURAL HEARING-LOSS | MUTAGENESIS SCREENS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | GENETICS & HEREDITY | MICE | DEAFNESS | THRESHOLDS | GENOME-WIDE ASSOCIATION | IMPAIRMENT
Journal Article
Biophysical Journal, ISSN 0006-3495, 2011, Volume 100, Issue 3, pp. 430a - 430a
Journal Article
by Dickinson, Mary E and Flenniken, Ann M and Ji, Xiao and Teboul, Lydia and Wong, Michael D and White, Jacqueline K and Meehan, Terrence F and Weninger, Wolfgang J and Westerberg, Henrik and Adissu, Hibret and Baker, Candice N and Bower, Lynette and Brown, James M and Brianna Caddle, L and Chiani, Francesco and Clary, Dave and Cleak, James and Daly, Mark J and Denegre, James M and Doe, Brendan and Dolan, Mary E and Edie, Sarah M and Fuchs, Helmut and Gailus-Durner, Valerie and Galli, Antonella and Gambadoro, Alessia and Gallegos, Juan and Guo, Shiying and Horner, Neil R and Hsu, Chih-wei and Johnson, Sara J and Kalaga, Sowmya and Keith, Lance C and Lanoue, Louise and Lawson, Thomas N and Lek, Monkol and Mark, Manuel and Marschall, Susan and Mason, Jeremy and McElwee, Melissa L and Newbigging, Susan and Nutter, Lauryl M.J and Peterson, Kevin A and Ramirez-Solis, Ramiro and Rowland, Douglas J and Ryder, Edward and Samocha, Kaitlin E and Seavitt, John R and Selloum, Mohammed and Szoke-Kovacs, Zsombor and Tamura, Masaru and Trainor, Amanda G and Tudose, Ilinca and Wakana, Shigeharu and Warren, Jonathan and Wendling, Olivia and West, David B and Wong, Leeyean and Yoshiki, Atsushi and MacArthur, Daniel G and Tocchini-Valentini, Glauco P and Gao, Xiang and Flicek, Paul and Bradley, Allan and Skarnes, William C and Justice, Monica J and Parkinson, Helen E and Moore, Mark and Wells, Sara and Braun, Robert E and Svenson, Karen L and Hrabe de Angelis, Martin and Herault, Yann and Mohun, Tim and Mallon, Ann-Marie and Mark Henkelman, R and Brown, Steve D.M and Adams, David J and Kent Lloyd, K.C and McKerlie, Colin and Beaudet, Arthur L and Bucan, Maja and Murray, Stephen A and McKay, Matthew and Urban, Barbara and Lund, Caroline and Froeter, Erin and LaCasse, Taylor and Mehalow, Adrienne and Gordon, Emily and Donahue, Leah Rae and Taft, Robert and Kutney, Peter and Dion, Stephanie and Goodwin, Leslie and Kales, Susan and Urban, Rachel and Palmer, Kristina and Pertuy, Fabien and Bitz, Deborah and ... and Int Mouse Phenotyping Consortium and The International Mouse Phenotyping Consortium
Nature, ISSN 0028-0836, 09/2016, Volume 537, Issue 7621, pp. 508 - 514
Approximately one-third of all mammalian genes are essential for life. Phenotypes resulting from knockouts of these genes in mice have provided tremendous... 
MICRO-CT | MULTIDISCIPLINARY SCIENCES | DISEASE | GENOME-WIDE | MAMMALIAN GENE-FUNCTION | SCREENS | GLYCOGENIN-1 DEFICIENCY | IDENTIFICATION | EXPRESSION | MOUSE EMBRYO | RESOURCE | Genetic research | Phenotype | Research | High-throughput screening (Biochemical assaying) | Methods | Genotype & phenotype | Disease | Developmental biology | Genes | Genomes | Mutation | Embryos | knockout | embryonic lethal | mouse | KOMP | IMPC | EUCOMM
Journal Article
DMM Disease Models and Mechanisms, ISSN 1754-8403, 05/2012, Volume 5, Issue 3, pp. 289 - 292
Journal Article
Nature Reviews Genetics, ISSN 1471-0056, 06/2018, Volume 19, Issue 6, pp. 357 - 370
Journal Article
Genome Biology, ISSN 1474-7596, 2013, Volume 14, Issue 7, pp. R82 - R82
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2017, Volume 49, Issue 8, pp. 1231 - 1238
Journal Article