ELECTROPHORESIS, ISSN 0173-0835, 12/2000, Volume 21, Issue 18, pp. 3931 - 3951
This review is devoted to the rapid developments in the field of microfluidic separation devices in which the flow is electrokinetically driven, and where the...
Chips capillary electrophoresis | Separation systems | Review | Microfluidics | Micro‐total analysis systems | Proteomics | Micro-total analysis systems | chips capillary electrophoresis | CHEMISTRY, ANALYTICAL | separation systems | proteomics | BIOCHEMICAL RESEARCH METHODS | micro-total analysis systems | LASER-INDUCED FLUORESCENCE | ELECTROOSMOTIC FLOW | CAPILLARY ARRAY ELECTROPHORESIS | DNA ANALYSIS | ELECTROSPRAY MASS-SPECTROMETRY | POLYMERASE-CHAIN-REACTION | MICROFLUIDIC ANALYTICAL SYSTEMS | MICROCHIP ELECTROPHORESIS | review | INDIRECT FLUORESCENCE DETECTION | microfluidics | SOLID-PHASE EXTRACTION | Animals | DNA - analysis | Oligonucleotide Array Sequence Analysis - methods | Humans | Chromatography - methods | Kinetics | Electrophoresis, Capillary - methods
Chips capillary electrophoresis | Separation systems | Review | Microfluidics | Micro‐total analysis systems | Proteomics | Micro-total analysis systems | chips capillary electrophoresis | CHEMISTRY, ANALYTICAL | separation systems | proteomics | BIOCHEMICAL RESEARCH METHODS | micro-total analysis systems | LASER-INDUCED FLUORESCENCE | ELECTROOSMOTIC FLOW | CAPILLARY ARRAY ELECTROPHORESIS | DNA ANALYSIS | ELECTROSPRAY MASS-SPECTROMETRY | POLYMERASE-CHAIN-REACTION | MICROFLUIDIC ANALYTICAL SYSTEMS | MICROCHIP ELECTROPHORESIS | review | INDIRECT FLUORESCENCE DETECTION | microfluidics | SOLID-PHASE EXTRACTION | Animals | DNA - analysis | Oligonucleotide Array Sequence Analysis - methods | Humans | Chromatography - methods | Kinetics | Electrophoresis, Capillary - methods
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 05/2010, Volume 38, Issue 5, pp. 808 - 816
Deferasirox (ICL670) is a novel once-daily, orally administered iron chelator to treat chronic iron overload in patients with transfusion-dependent anemias....
PERFORMANCE LIQUID-CHROMATOGRAPHY | TRIAL | CELLS | COMPLEX | MANAGEMENT | PROTEIN | PLASMA | ICL670 | CHELATOR | PHARMACOLOGY & PHARMACY | BIOAVAILABILITY | Benzoates - adverse effects | Triazoles - adverse effects | Benzoates - therapeutic use | Iron Overload - drug therapy | Area Under Curve | Benzoates - metabolism | Glucuronides - analysis | Humans | Glucuronidase - metabolism | Male | Iron Chelating Agents - metabolism | Sulfuric Acid Esters - metabolism | Young Adult | Glucuronides - metabolism | Spectrometry, Mass, Electrospray Ionization | Adult | Female | Triazoles - pharmacokinetics | Molecular Structure | Triazoles - therapeutic use | Iron Chelating Agents - therapeutic use | beta-Thalassemia - therapy | Hydroxylation | Cells, Cultured | Rats | Sulfuric Acid Esters - analysis | Arylsulfatases - metabolism | Iron Chelating Agents - adverse effects | Transfusion Reaction | Triazoles - metabolism | Animals | Feces - chemistry | Iron Chelating Agents - pharmacokinetics | Benzoates - pharmacokinetics | Hepatocytes - enzymology
PERFORMANCE LIQUID-CHROMATOGRAPHY | TRIAL | CELLS | COMPLEX | MANAGEMENT | PROTEIN | PLASMA | ICL670 | CHELATOR | PHARMACOLOGY & PHARMACY | BIOAVAILABILITY | Benzoates - adverse effects | Triazoles - adverse effects | Benzoates - therapeutic use | Iron Overload - drug therapy | Area Under Curve | Benzoates - metabolism | Glucuronides - analysis | Humans | Glucuronidase - metabolism | Male | Iron Chelating Agents - metabolism | Sulfuric Acid Esters - metabolism | Young Adult | Glucuronides - metabolism | Spectrometry, Mass, Electrospray Ionization | Adult | Female | Triazoles - pharmacokinetics | Molecular Structure | Triazoles - therapeutic use | Iron Chelating Agents - therapeutic use | beta-Thalassemia - therapy | Hydroxylation | Cells, Cultured | Rats | Sulfuric Acid Esters - analysis | Arylsulfatases - metabolism | Iron Chelating Agents - adverse effects | Transfusion Reaction | Triazoles - metabolism | Animals | Feces - chemistry | Iron Chelating Agents - pharmacokinetics | Benzoates - pharmacokinetics | Hepatocytes - enzymology
Journal Article
Health Psychology, ISSN 0278-6133, 7/2010, Volume 29, Issue 4, pp. 421 - 428
Objective: To investigated the effectiveness of an adherence intervention (AIMS) designed to fit HIV-clinics' routine care procedures. Design: Through block...
Adherence | Behavioral interventions | HIV | Patient compliance | Randomized controlled trial | VIRAL LOAD | patient compliance | MEDICATIONS | adherence | ANTIRETROVIRAL THERAPY ADHERENCE | behavioral interventions | PSYCHOLOGY, CLINICAL | FAILURE | PROTEASE INHIBITORS | CARE | PSYCHOLOGY | randomized controlled trial | INTERVENTIONS | CLINICAL-TRIALS | IMPROVE ADHERENCE | OUTCOMES | Anti-Retroviral Agents - therapeutic use | Follow-Up Studies | HIV Infections - virology | Humans | Middle Aged | HIV Infections - psychology | Male | Treatment Outcome | Viral Load | Patient Compliance - statistics & numerical data | Young Adult | Netherlands | Counseling | Adult | Drug Monitoring - instrumentation | Female | HIV Infections - drug therapy | Surveys and Questionnaires | Aged | Program Evaluation | Drug Packaging - instrumentation | Health counseling | Influence | Care and treatment | HIV infection | viral load | interventions | outcomes | clinical-trials | failure | medications | antiretroviral therapy adherence | protease inhibitors | improve adherence | care
Adherence | Behavioral interventions | HIV | Patient compliance | Randomized controlled trial | VIRAL LOAD | patient compliance | MEDICATIONS | adherence | ANTIRETROVIRAL THERAPY ADHERENCE | behavioral interventions | PSYCHOLOGY, CLINICAL | FAILURE | PROTEASE INHIBITORS | CARE | PSYCHOLOGY | randomized controlled trial | INTERVENTIONS | CLINICAL-TRIALS | IMPROVE ADHERENCE | OUTCOMES | Anti-Retroviral Agents - therapeutic use | Follow-Up Studies | HIV Infections - virology | Humans | Middle Aged | HIV Infections - psychology | Male | Treatment Outcome | Viral Load | Patient Compliance - statistics & numerical data | Young Adult | Netherlands | Counseling | Adult | Drug Monitoring - instrumentation | Female | HIV Infections - drug therapy | Surveys and Questionnaires | Aged | Program Evaluation | Drug Packaging - instrumentation | Health counseling | Influence | Care and treatment | HIV infection | viral load | interventions | outcomes | clinical-trials | failure | medications | antiretroviral therapy adherence | protease inhibitors | improve adherence | care
Journal Article
Health psychology, ISSN 0278-6133, 2012, Volume 31, Issue 6, pp. 695 - 703
Understanding the gap between people's intentions and actual health behavior is an important issue in health psychology. Our aim in this study was to...
Physical exercise | Treatment adherence | Self regulation | Intention behavior gap | Control theory | METAANALYSIS | control theory | EFFICACY | ANTIRETROVIRAL THERAPY | self regulation | PSYCHOLOGY, CLINICAL | PSYCHOLOGY | HIV-INFECTED PATIENTS | PLANNED BEHAVIOR | TEMPORAL STABILITY | treatment adherence | MODERATORS | intention behavior gap | PHYSICAL-ACTIVITY | HEALTH | physical exercise | INTERVENTION | Medication Adherence - psychology | Follow-Up Studies | Humans | Middle Aged | Male | Exercise - psychology | Self Care - psychology | Adult | Female | HIV Infections - drug therapy | Intention | Surveys and Questionnaires | Aged | Psychological aspects | Care and treatment | Self-control | Health behavior | HIV patients | Research | Patient compliance | metaanalysis | physical-activity | psychology | antiretroviral therapy | temporal stability | hiv-infected patients | health | planned behavior | intervention | moderators
Physical exercise | Treatment adherence | Self regulation | Intention behavior gap | Control theory | METAANALYSIS | control theory | EFFICACY | ANTIRETROVIRAL THERAPY | self regulation | PSYCHOLOGY, CLINICAL | PSYCHOLOGY | HIV-INFECTED PATIENTS | PLANNED BEHAVIOR | TEMPORAL STABILITY | treatment adherence | MODERATORS | intention behavior gap | PHYSICAL-ACTIVITY | HEALTH | physical exercise | INTERVENTION | Medication Adherence - psychology | Follow-Up Studies | Humans | Middle Aged | Male | Exercise - psychology | Self Care - psychology | Adult | Female | HIV Infections - drug therapy | Intention | Surveys and Questionnaires | Aged | Psychological aspects | Care and treatment | Self-control | Health behavior | HIV patients | Research | Patient compliance | metaanalysis | physical-activity | psychology | antiretroviral therapy | temporal stability | hiv-infected patients | health | planned behavior | intervention | moderators
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 12/2008, Volume 36, Issue 12, pp. 2523 - 2538
Deferasirox (Exjade, ICL670, CGP72670) is an iron-chelating drug for p.o. treatment of transfusional iron overload in patients with β-thalassemia or sickle...
PULSED-FIELD GRADIENTS | NMR | CHELATING THERAPY | THALASSEMIA | ICL670 | SENSITIVITY | PHARMACOLOGY & PHARMACY | ABSORPTION | PARAMETERS | DISPOSITION | CORRELATION SPECTROSCOPY | Triazoles - administration & dosage | Blood Chemical Analysis | Rats, Wistar | Benzoates - metabolism | Bile - chemistry | Rats, Long-Evans | Fetus - metabolism | Male | Iron Chelating Agents - metabolism | Milk, Human - chemistry | Iron - analysis | Tissue Distribution | ATP-Binding Cassette Transporters - genetics | Animals, Suckling - metabolism | Mass Spectrometry | ATP-Binding Cassette Transporters - metabolism | Female | Triazoles - pharmacokinetics | Iron Chelating Agents - administration & dosage | Molecular Structure | Milk, Human - metabolism | Magnetic Resonance Spectroscopy | Rats, Transgenic | Urine - chemistry | Rats | Iron - metabolism | Benzoates - administration & dosage | Placenta - metabolism | Pregnancy | Triazoles - metabolism | Animals | Feces - chemistry | Iron Chelating Agents - pharmacology | Models, Biological | Benzoates - pharmacokinetics | Enterohepatic Circulation
PULSED-FIELD GRADIENTS | NMR | CHELATING THERAPY | THALASSEMIA | ICL670 | SENSITIVITY | PHARMACOLOGY & PHARMACY | ABSORPTION | PARAMETERS | DISPOSITION | CORRELATION SPECTROSCOPY | Triazoles - administration & dosage | Blood Chemical Analysis | Rats, Wistar | Benzoates - metabolism | Bile - chemistry | Rats, Long-Evans | Fetus - metabolism | Male | Iron Chelating Agents - metabolism | Milk, Human - chemistry | Iron - analysis | Tissue Distribution | ATP-Binding Cassette Transporters - genetics | Animals, Suckling - metabolism | Mass Spectrometry | ATP-Binding Cassette Transporters - metabolism | Female | Triazoles - pharmacokinetics | Iron Chelating Agents - administration & dosage | Molecular Structure | Milk, Human - metabolism | Magnetic Resonance Spectroscopy | Rats, Transgenic | Urine - chemistry | Rats | Iron - metabolism | Benzoates - administration & dosage | Placenta - metabolism | Pregnancy | Triazoles - metabolism | Animals | Feces - chemistry | Iron Chelating Agents - pharmacology | Models, Biological | Benzoates - pharmacokinetics | Enterohepatic Circulation
Journal Article
Bone, ISSN 8756-3282, 2011, Volume 49, Issue 2, pp. 233 - 241
Abstract Parathyroid hormone (PTH), when injected daily as either the intact hormone PTH(1–84) or the active fragment PTH(1–34) (teriparatide), is an...
Orthopedics | Osteoporosis | Bone formation | Calcilytics | Parathyroid hormone | Teriparatide | INDUCED OSTEOPOROSIS | CLINICAL-TRIAL | PTH | RECEPTOR ANTAGONIST | ALENDRONATE | TERIPARATIDE TREATMENT | THERAPY | VERTEBRAL FRACTURE RISK | MEN | ENDOCRINOLOGY & METABOLISM | POSTMENOPAUSAL WOMEN | Rats, Wistar | Calcium - metabolism | Humans | Rats | Male | Parathyroid Hormone - pharmacology | Bone and Bones - drug effects | Bone Density - drug effects | Anabolic Agents - pharmacology | Animals | Parathyroid Hormone - metabolism | Bone and Bones - metabolism | Dogs | Adult | Female | Molecular Structure | Anabolic Agents - pharmacokinetics | Quinazolinones - pharmacology | Receptors, Calcium-Sensing - antagonists & inhibitors | Quinazolinones - pharmacokinetics
Orthopedics | Osteoporosis | Bone formation | Calcilytics | Parathyroid hormone | Teriparatide | INDUCED OSTEOPOROSIS | CLINICAL-TRIAL | PTH | RECEPTOR ANTAGONIST | ALENDRONATE | TERIPARATIDE TREATMENT | THERAPY | VERTEBRAL FRACTURE RISK | MEN | ENDOCRINOLOGY & METABOLISM | POSTMENOPAUSAL WOMEN | Rats, Wistar | Calcium - metabolism | Humans | Rats | Male | Parathyroid Hormone - pharmacology | Bone and Bones - drug effects | Bone Density - drug effects | Anabolic Agents - pharmacology | Animals | Parathyroid Hormone - metabolism | Bone and Bones - metabolism | Dogs | Adult | Female | Molecular Structure | Anabolic Agents - pharmacokinetics | Quinazolinones - pharmacology | Receptors, Calcium-Sensing - antagonists & inhibitors | Quinazolinones - pharmacokinetics
Journal Article
Bone, ISSN 8756-3282, 2014, Volume 64, pp. 204 - 210
Abstract Antagonism of the calcium-sensing receptor in the parathyroid gland leads to parathyroid hormone (PTH) release. Calcilytics are a new class of...
Orthopedics | Osteoporosis | Bone formation | Calcilytics | Parathyroid hormone | Teriparatide | CASR | ANTAGONIST | CALCIUM-SENSING RECEPTOR | BONE-MINERAL DENSITY | PTH | RONACALERET | ENDOCRINOLOGY & METABOLISM | Double-Blind Method | Administration, Oral | Humans | Middle Aged | Quinazolinones - administration & dosage | Case-Control Studies | Dose-Response Relationship, Drug | Parathyroid Hormone - metabolism | Placebos | Postmenopause | Female | Quinazolinones - pharmacology | Quinazolinones - pharmacokinetics | Women | Postmenopausal women | Health aspects | Analysis
Orthopedics | Osteoporosis | Bone formation | Calcilytics | Parathyroid hormone | Teriparatide | CASR | ANTAGONIST | CALCIUM-SENSING RECEPTOR | BONE-MINERAL DENSITY | PTH | RONACALERET | ENDOCRINOLOGY & METABOLISM | Double-Blind Method | Administration, Oral | Humans | Middle Aged | Quinazolinones - administration & dosage | Case-Control Studies | Dose-Response Relationship, Drug | Parathyroid Hormone - metabolism | Placebos | Postmenopause | Female | Quinazolinones - pharmacology | Quinazolinones - pharmacokinetics | Women | Postmenopausal women | Health aspects | Analysis
Journal Article
Analytical Chemistry, ISSN 0003-2700, 09/1997, Volume 69, Issue 17, pp. 3451 - 3457
Microchips for integrated capillary electrophoresis systems were produced by molding a poly(dimethylsiloxane) (PDMS) silicone elastomer against a...
K EA CHEMISTRY, ANALYTICAL | SEPARATIONS | CHEMISTRY, ANALYTICAL | POSTCOLUMN REACTOR | FLUORESCENT INTERCALATING DYES | SYSTEMS | DEVICES | GLASS CHIPS | MICROFABRICATION | FLOW | LIQUIDS
K EA CHEMISTRY, ANALYTICAL | SEPARATIONS | CHEMISTRY, ANALYTICAL | POSTCOLUMN REACTOR | FLUORESCENT INTERCALATING DYES | SYSTEMS | DEVICES | GLASS CHIPS | MICROFABRICATION | FLOW | LIQUIDS
Journal Article
The Lancet, ISSN 0140-6736, 12/2001, Volume 358, Issue 9296, pp. 1864 - 1869
3,4-methylenedioxymethamphetamine (MDMA or ecstasy) is a popular recreational drug that has been shown to damage brain serotonin neurons in high doses....
NONHUMAN-PRIMATES | MEDICINE, GENERAL & INTERNAL | POSITRON-EMISSION-TOMOGRAPHY | BETA-CIT BINDING | 52-WEEK PERIOD | IN-VIVO | DOPAMINE TRANSPORTERS | HUMANS | PARTIAL RECOVERY | NEUROTOXICITY | METHYLENEDIOXYMETHAMPHETAMINE | Brain - diagnostic imaging | N-Methyl-3,4-methylenedioxyamphetamine - administration & dosage | Depression - epidemiology | Prevalence | Humans | N-Methyl-3,4-methylenedioxyamphetamine - adverse effects | Netherlands - epidemiology | Serotonin Agents - administration & dosage | Tomography, Emission-Computed, Single-Photon | Male | Serotonin Agents - metabolism | Case-Control Studies | Serotonin Agents - adverse effects | Brain - drug effects | Brain - metabolism | Dose-Response Relationship, Drug | N-Methyl-3,4-methylenedioxyamphetamine - metabolism | Sex Distribution | Adult | Female | Neurons - metabolism | Radioligand Assay | Neurons - drug effects | Binding Sites | Physiological aspects | Neurotransmitters | Serotonin | Ecstasy (Drug) | Amphetamines | Brain | Neurons | Toxicity | Cerebellum | Ecstasy | Binding | Urine | Women | Drug abuse | Sex | Sex differences | Single photon emission computed tomography | MDMA | Studies | Neurotoxicity | Computed tomography | Gender aspects | Tomography | Brain damage | Drug dosages | Tropane | Brain injury | Long-term effects
NONHUMAN-PRIMATES | MEDICINE, GENERAL & INTERNAL | POSITRON-EMISSION-TOMOGRAPHY | BETA-CIT BINDING | 52-WEEK PERIOD | IN-VIVO | DOPAMINE TRANSPORTERS | HUMANS | PARTIAL RECOVERY | NEUROTOXICITY | METHYLENEDIOXYMETHAMPHETAMINE | Brain - diagnostic imaging | N-Methyl-3,4-methylenedioxyamphetamine - administration & dosage | Depression - epidemiology | Prevalence | Humans | N-Methyl-3,4-methylenedioxyamphetamine - adverse effects | Netherlands - epidemiology | Serotonin Agents - administration & dosage | Tomography, Emission-Computed, Single-Photon | Male | Serotonin Agents - metabolism | Case-Control Studies | Serotonin Agents - adverse effects | Brain - drug effects | Brain - metabolism | Dose-Response Relationship, Drug | N-Methyl-3,4-methylenedioxyamphetamine - metabolism | Sex Distribution | Adult | Female | Neurons - metabolism | Radioligand Assay | Neurons - drug effects | Binding Sites | Physiological aspects | Neurotransmitters | Serotonin | Ecstasy (Drug) | Amphetamines | Brain | Neurons | Toxicity | Cerebellum | Ecstasy | Binding | Urine | Women | Drug abuse | Sex | Sex differences | Single photon emission computed tomography | MDMA | Studies | Neurotoxicity | Computed tomography | Gender aspects | Tomography | Brain damage | Drug dosages | Tropane | Brain injury | Long-term effects
Journal Article
ELECTROPHORESIS, ISSN 0173-0835, 05/2002, Volume 23, Issue 9, pp. 1255 - 1262
Highly efficient capillary electrochromatographic separations of cardiac glycosides and other steroids are presented. Employing butyl‐derivatized silica...
Antibodies | Capillary electrochromatography | Immunoaffinity screening | Digoxin | CHEMISTRY, ANALYTICAL | QUANTIFICATION | DRUG DISCOVERY | BIOCHEMICAL RESEARCH METHODS | digoxin | ONLINE | immunoaffinity screening | LIBRARIES | capillary electrochromatography | ELECTROPHORESIS | COMBINATORIAL CHEMISTRY | antibodies | AFFINITY-CHROMATOGRAPHY | MASS-SPECTROMETRIC DETECTION | Digoxigenin - isolation & purification | Digitoxin - immunology | Chromatography, High Pressure Liquid | Digoxin - isolation & purification | Digoxin - immunology | Immunosorbent Techniques | Chromatography, Affinity | Steroids - isolation & purification | Cardiac Glycosides - immunology | Cardiac Glycosides - isolation & purification | Electrophoresis, Capillary - methods | Immunoglobulin Fab Fragments | Digitoxin - isolation & purification | Digoxigenin - immunology
Antibodies | Capillary electrochromatography | Immunoaffinity screening | Digoxin | CHEMISTRY, ANALYTICAL | QUANTIFICATION | DRUG DISCOVERY | BIOCHEMICAL RESEARCH METHODS | digoxin | ONLINE | immunoaffinity screening | LIBRARIES | capillary electrochromatography | ELECTROPHORESIS | COMBINATORIAL CHEMISTRY | antibodies | AFFINITY-CHROMATOGRAPHY | MASS-SPECTROMETRIC DETECTION | Digoxigenin - isolation & purification | Digitoxin - immunology | Chromatography, High Pressure Liquid | Digoxin - isolation & purification | Digoxin - immunology | Immunosorbent Techniques | Chromatography, Affinity | Steroids - isolation & purification | Cardiac Glycosides - immunology | Cardiac Glycosides - isolation & purification | Electrophoresis, Capillary - methods | Immunoglobulin Fab Fragments | Digitoxin - isolation & purification | Digoxigenin - immunology
Journal Article
ELECTROPHORESIS, ISSN 0173-0835, 1997, Volume 18, Issue 12‐13, pp. 2203 - 2213
Integrated capillary electrophoresis (ICE) is emerging as a new analytical tool allowing fast, automated, miniaturized and multiplexed assays, thus meeting the...
Integrated capillary electrophoresis | Analytical instrumentation | Biopolymer analysis | Immunoassays | analytical instrumentation | CHEMISTRY, ANALYTICAL | CHEMICAL-ANALYSIS SYSTEMS | POSTCOLUMN REACTOR | BIOCHEMICAL RESEARCH METHODS | CYCLIC PLANAR MICROSTRUCTURE | immunoassays | biopolymer analysis | GLASS CHIPS | DNA ANALYSIS | integrated capillary electrophoresis | LIQUID-CHROMATOGRAPHY | MICROCHIP ELECTROPHORESIS | ZONE ELECTROPHORESIS | SAMPLE INJECTION | SEPARATION SYSTEMS | Automation | Animals | Electrophoresis, Capillary - methods | Electrophoresis, Capillary - instrumentation | Humans
Integrated capillary electrophoresis | Analytical instrumentation | Biopolymer analysis | Immunoassays | analytical instrumentation | CHEMISTRY, ANALYTICAL | CHEMICAL-ANALYSIS SYSTEMS | POSTCOLUMN REACTOR | BIOCHEMICAL RESEARCH METHODS | CYCLIC PLANAR MICROSTRUCTURE | immunoassays | biopolymer analysis | GLASS CHIPS | DNA ANALYSIS | integrated capillary electrophoresis | LIQUID-CHROMATOGRAPHY | MICROCHIP ELECTROPHORESIS | ZONE ELECTROPHORESIS | SAMPLE INJECTION | SEPARATION SYSTEMS | Automation | Animals | Electrophoresis, Capillary - methods | Electrophoresis, Capillary - instrumentation | Humans
Journal Article
Journal of Chromatography A, ISSN 0021-9673, 2006, Volume 1133, Issue 1, pp. 184 - 194
Sensitive radioactivity detection following high performance liquid chromatography (HPLC) separation remains a challenge in many drug metabolism studies with...
Microplate scintillation counter | Animal and human ADME studies | Offline HPLC radioactivity detection | animal and human ADME studies | CHEMISTRY, ANALYTICAL | offline HPLC radioactivity detection | microplate scintillation counter | ONLINE | BIOCHEMICAL RESEARCH METHODS | Scintillation Counting - methods | Reproducibility of Results | Animals | Chromatography, High Pressure Liquid - methods | Radioisotopes - analysis | Pharmaceutical Preparations - chemistry | Rats | Pharmaceutical Preparations - analysis | Radioisotopes - chemistry | Physiological aspects | Liquid chromatography | Analytical instruments | Metabolites | Detectors
Microplate scintillation counter | Animal and human ADME studies | Offline HPLC radioactivity detection | animal and human ADME studies | CHEMISTRY, ANALYTICAL | offline HPLC radioactivity detection | microplate scintillation counter | ONLINE | BIOCHEMICAL RESEARCH METHODS | Scintillation Counting - methods | Reproducibility of Results | Animals | Chromatography, High Pressure Liquid - methods | Radioisotopes - analysis | Pharmaceutical Preparations - chemistry | Rats | Pharmaceutical Preparations - analysis | Radioisotopes - chemistry | Physiological aspects | Liquid chromatography | Analytical instruments | Metabolites | Detectors
Journal Article
Psychopharmacology, ISSN 0033-3158, 2002, Volume 159, Issue 3, pp. 335 - 340
RATIONALE: Tablets sold as ecstasy often contain not only 3,4-methylenedioxymethamphetamine (MDMA) but other compounds well known to cause dopaminergic...
Neurosciences | Biomedicine | Pharmacology/Toxicology | Psychiatry | Ecstasy Amphetamine Neurotoxicity DA transporter [123I]β-CIT SPECT | Ecstasy | Neurotoxicity | Amphetamine | [ | DA transporter | I]β-CIT SPECT | SEROTONIN TRANSPORTER | METHAMPHETAMINE | PSYCHIATRY | ecstasy | amphetamine | NEUROSCIENCES | [I-123]beta-CIT SPECT | neurotoxicity | POSITRON-EMISSION-TOMOGRAPHY | IN-VIVO | 3,4-METHYLENEDIOXYMETHAMPHETAMINE MDMA | PHARMACOLOGY & PHARMACY | RAT-BRAIN | BINDING | I-123 BETA-CIT | C-11 WIN-35,428 | Cocaine - metabolism | Confidence Intervals | Tomography, Emission-Computed, Single-Photon - methods | Humans | Middle Aged | Male | Amphetamine - metabolism | Nerve Tissue Proteins | Dopamine Uptake Inhibitors - metabolism | Cocaine - analogs & derivatives | Corpus Striatum - metabolism | N-Methyl-3,4-methylenedioxyamphetamine - metabolism | Radiopharmaceuticals - metabolism | Adrenergic Uptake Inhibitors - metabolism | Iodine Radioisotopes - metabolism | Analysis of Variance | Adolescent | Adult | Female | Membrane Transport Proteins - metabolism | Membrane Glycoproteins | Dopamine Plasma Membrane Transport Proteins | Tomography, Emission-Computed, Single-Photon - statistics & numerical data
Neurosciences | Biomedicine | Pharmacology/Toxicology | Psychiatry | Ecstasy Amphetamine Neurotoxicity DA transporter [123I]β-CIT SPECT | Ecstasy | Neurotoxicity | Amphetamine | [ | DA transporter | I]β-CIT SPECT | SEROTONIN TRANSPORTER | METHAMPHETAMINE | PSYCHIATRY | ecstasy | amphetamine | NEUROSCIENCES | [I-123]beta-CIT SPECT | neurotoxicity | POSITRON-EMISSION-TOMOGRAPHY | IN-VIVO | 3,4-METHYLENEDIOXYMETHAMPHETAMINE MDMA | PHARMACOLOGY & PHARMACY | RAT-BRAIN | BINDING | I-123 BETA-CIT | C-11 WIN-35,428 | Cocaine - metabolism | Confidence Intervals | Tomography, Emission-Computed, Single-Photon - methods | Humans | Middle Aged | Male | Amphetamine - metabolism | Nerve Tissue Proteins | Dopamine Uptake Inhibitors - metabolism | Cocaine - analogs & derivatives | Corpus Striatum - metabolism | N-Methyl-3,4-methylenedioxyamphetamine - metabolism | Radiopharmaceuticals - metabolism | Adrenergic Uptake Inhibitors - metabolism | Iodine Radioisotopes - metabolism | Analysis of Variance | Adolescent | Adult | Female | Membrane Transport Proteins - metabolism | Membrane Glycoproteins | Dopamine Plasma Membrane Transport Proteins | Tomography, Emission-Computed, Single-Photon - statistics & numerical data
Journal Article
Analytical Chemistry, ISSN 0003-2700, 08/2000, Volume 72, Issue 16, pp. 3956 - 3959
In miniaturized separation techniques, such as capillary electrophoresis (CE) or capillary liquid chromatography (LC), conventional on-line radioactivity...
LIQUID-CHROMATOGRAPHY | CHEMISTRY, ANALYTICAL | Scintillation Counting - methods | Pharmaceutical Preparations - metabolism | Animals | Urine - chemistry | Radiochemistry | Rats | Miniaturization | Usage | Analysis | Drug metabolism | Radioisotope scanning | Design and construction | Miniature electronic equipment | Methods | High performance liquid chromatography
LIQUID-CHROMATOGRAPHY | CHEMISTRY, ANALYTICAL | Scintillation Counting - methods | Pharmaceutical Preparations - metabolism | Animals | Urine - chemistry | Radiochemistry | Rats | Miniaturization | Usage | Analysis | Drug metabolism | Radioisotope scanning | Design and construction | Miniature electronic equipment | Methods | High performance liquid chromatography
Journal Article