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by Wain, Louise V and Vaez, Ahmad and Jansen, Rick and Joehanes, Roby and van der Most, Peter J and Erzurumluoglu, A Mesut and O'Reilly, Paul F and Cabrera, Claudia P and Warren, Helen R and Rose, Lynda M and Verwoert, Germaine C and Hottenga, Jouke-Jan and Strawbridge, Rona J and Esko, Tonu and Arking, Dan E and Hwang, Shih-Jen and Guo, Xiuqing and Kutalik, Zoltan and Trompet, Stella and Shrine, Nick and Teumer, Alexander and Ried, Janina S and Bis, Joshua C and Smith, Albert V and Amin, Najaf and Nolte, Ilja M and Lyytikäinen, Leo-Pekka and Mahajan, Anubha and Wareham, Nicholas J and Hofer, Edith and Joshi, Peter K and Kristiansson, Kati and Traglia, Michela and Havulinna, Aki S and Goel, Anuj and Nalls, Mike A and Sõber, Siim and Vuckovic, gana and Luan, Jian'an and Del Greco M, Fabiola and Ayers, Kristin L and Marrugat, Jaume and Ruggiero, Daniela and Lopez, Lorna M and Niiranen, Teemu and Enroth, Stefan and Jackson, Anne U and Nelson, Christopher P and Huffman, Jennifer E and Zhang, Weihua and Marten, Jonathan and Gandin, Ilaria and Harris, Sarah E and Zemunik, Tatijana and Lu, Yingchang and Evangelou, Evangelos and Shah, Nabi and de Borst, Martin H and Mangino, Massimo and Prins, Bram P and Campbell, Archie and Li-Gao, Ruifang and Chauhan, Ganesh and Oldmeadow, Christopher and Abecasis, Gonçalo and Abedi, Maryam and Barbieri, Caterina M and Barnes, Michael R and Batini, Chiara and Beilby, John and Blake, Tineka and Boehnke, Michael and Bottinger, Erwin P and Braund, Peter S and Brown, Morris and Brumat, Marco and Campbell, Harry and Chambers, John C and Cocca, Massimiliano and Collins, Francis and Connell, John and Cordell, Heather J and Damman, Jeffrey J and Davies, Gail and de Geus, Eco J and de Mutsert, Renée and Deelen, Joris and Demirkale, Yusuf and Doney, Alex S F and Dörr, Marcus and Farrall, Martin and Ferreira, Teresa and Frånberg, Mattias and Gao, He and Gieaitis, Vilmantas and Gieger, Christian and Giulianini, Franco and Gow, Alan J and Hamsten, Anders and Harris, Tamara B and ... and Lifelines Cohort Study and Understanding Soc Sci Grp and BIOS Consortium and Understanding Society Scientific Group and Stockholms universitet and Numerisk analys och datalogi (NADA) and Naturvetenskapliga fakulteten
Hypertension, ISSN 0194-911X, 09/2017, Volume 70, Issue 3, pp. E4 - +
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2018, Volume 50, Issue 10, pp. 1412 - +
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2017, Volume 49, Issue 6, pp. 834 - 841
The timing of puberty is a highly polygenic childhood trait that is epidemiologically associated with various adult diseases. Using 1000 Genomes... 
REGRESSION | METAANALYSIS | METABOLISM | GROWTH | BODY-MASS INDEX | LOCI | WIDE ASSOCIATION | MENDELIAN RANDOMIZATION | TRAITS | INHERITANCE | GENETICS & HEREDITY | Body Mass Index | Genomic Imprinting | Genetic Predisposition to Disease | Genome-Wide Association Study | Calcium-Binding Proteins | Age Factors | Membrane Proteins - genetics | Menarche - genetics | Humans | Risk Factors | Intercellular Signaling Peptides and Proteins - genetics | Databases, Genetic | Male | Puberty - genetics | Neoplasms - genetics | Adolescent | Female | Ribonucleoproteins - genetics | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Genetic variation | Menarche | Genetic aspects | Gene expression | Health aspects | Carcinogenesis | Risk factors | Enrichment | Transcription | Laboratories | Genomics | Genes | Risk | Genomes | Tissues | Preadipocyte factor 1 | Epidemiology | Variance | Complexity | Body mass index | Mens health | Randomization | Coding | Genetics | Trends | Children | Endometrium | Public health | Age | Medical research | Puberty | Internal medicine | Gynecology | Health risks | Time measurement | Obstetrics | Diseases | Medicine | Studies | Hospitals | Body mass | Womens health | Men | Breast | Links | Heritability | Polygenic inheritance | Prostate cancer | Prostate | Endocrinology | Cancer | InterAct Consortium | AOCS Investigators | PRACTICAL consortium | Endometrial Cancer Association Consortium | Ovarian Cancer Association Consortium | LifeLines Cohort Study | kConFab
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 05/2018, Volume 50, Issue 5, pp. 652 - 656
Journal Article
by Kilpeläinen, Tuomas and Bentley, Amy and Noordam, R and Sung, YJ and Schwander, K and Winkler, Thomas and Jakupovic, H and Chasman, Daniel and Manning, A and Ntalla, Ioanna and Aschard, Hugues and Brown, M.R and de Las Fuentes, L and Franceschini, Nora and Guo, Xiuqing and Vojinovic, D and Aslibekyan, S and Feitosa, Mary Furlan and Kho, M and Musani, SK and Richard, M and Wang, H.M and Wang, Zhen and Bartz, TM and Bielak, Lawrence F and Campbell, Archie and Dorajoo, Rajkumar and Fisher, V and Hartwig, F.P and Horimoto, A and Li, C.W and Lohman, Kurt and Marten, J and Sim, XL and Smith, Davey and Tajuddin, S. M and Alver, M and Amini, M and Boissel, M and Chai, J.F and Chen, Xishu and Divers, J and Evangelou, Evangelos and Gao, Cheng and Graff, Maud J.L and Harris, Sarah and He, Meian and Hsu, Fang-Chi and Jackson, Anne and Zhao, Jing Hua and Kraja, Aldi and Kuhnel, Brigitte and Laguzzi, F and Lyytikäinen, Leo-Pekka and Nolte, IM and Rauramaa, Rainer and Riaz, Muhammad and Robino, Antonietta and Rueedi, R and Stringham, Heather and Takeuchi, F and Most, Peter and Varga, Tibor and Verweij, Niek and Ware, EB and Wen, WQ and Li, X. Y and Yanek, Lisa and Amin, Najaf and Arnett, Donna and Boerwinkle, Eric and Brumat, M and Cade, B and Canouil, M and Chen, Yii-Der Ida and Concas, MP and Connell, John and Mutsert, Reneé and de Silva, H.J and de Vries, PS and Demirkan, Ayşe and Ding, Jingzhong and Eaton, CB and Faul, Jessica and Friedlander, Yechiel and Gabriel, K.P and Ghanbari, M and Giulianini, Franco and Gu, C.C and Gu, DF and Harris, Tamara and He, Jing and Heikkinen, S and Heng, Chew-Kiat and Hunt, Steven and Ikram, Arfan and Jonas, J.B and Koh, WP and Komulainen, Pirjo and Krieger, José and ... and Lifelines Cohort Study and et al
Nature Communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 1 - 11
Journal Article
by Feitosa, Mary Furlan and Kraja, Aldi and Chasman, Daniel and Sung, Y.J and Winkler, Thomas W and Ntalla, Ioanna and Guo, Xiuqing and Franceschini, Nora and Cheng, C.-Y and Sim, Xueling and Vojinović, Dina and Marten, Jonathan and Musani, S.K and Li, C and Bentley, Amy and Brown, M.R and Schwander, K and Richard, M.A and Noordam, R and Aschard, Hugues and Bartz, Traci M and Bielak, Lawrence F and Dorajoo, Rajkumar and Fisher, V and Hartwig, F.P and Horimoto, A.R.V.R and Lohman, K.K and Manning, Alisa and Rankinen, Tuomo and Smith, Albert and Tajuddin, S.M and Wojczynski, Mary and Alver, Maris and Boissel, M and Cai, Qiuyin and Campbell, Archie and Chai, J.F and Chen, X and Divers, J and Gao, C and Goel, Anuj and Hagemeijer, Y and Harris, Sarah and He, Meian and Hsu, F.-C and Jackson, Anne and Kähönen, Mika and Kasturiratne, A and Komulainen, P and Kuhnel, Brigitte and Laguzzi, F and Luan, J and Matoba, N and Nolte, Ilja and Padmanabhan, Sandosh and Riaz, M and Rueedi, R and Robino, Antonietta and Said, M.A and Scott, Robert and Sofer, T and Stancáková, Alena and Takeuchi, Fumihiko and Tayo, Bamidele and Most, Peter and Varga, Tibor V and Vitart, V and Wang, Y and Ware, Erin B and Warren, Helen and Weiss, S and Wen, W and Yanek, Lisa and Zhang, Weihua and Zhao, J.H and Afaq, S and Amin, Najaf and Amini, Marzyeh and Arking, Dan and Aung, Tin and Boerwinkle, E and Borecki, Ingrid and Broeckel, Ulrich and Brown, M and Brumat, M and Burke, Greg and Canouil, M and Chakravarti, Aravinda and Charumathi, S and Chen, Yii-Der Ida and Connell, J.M and Correa, D.D and De Las Fuentes, L and Mutsert, Reneé and De Silva, H.J and Deng, X and Ding, J and Duan, Qing and Eaton, C.B and Ehret, G and ... and InterAct Consortium
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0198166
textabstractHeavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP)... 
COMMON VARIANTS | ENVIRONMENT INTERACTION | METAANALYSIS | PTP4A1-PHF3-EYS VARIANTS | TRANSCRIPTION FACTOR GATA4 | MULTIDISCIPLINARY SCIENCES | RISK | LOCI | FUNCTIONAL VARIATION | GENOME-WIDE ASSOCIATION | DEPENDENCE | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Blood Pressure - genetics | Humans | Middle Aged | Male | Continental Population Groups - genetics | Gene-Environment Interaction | Alcohol Drinking - genetics | Young Adult | Alcohol Drinking - epidemiology | Pedigree | Adolescent | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Hypertension - epidemiology | Hypertension - genetics | Genetic Predisposition to Disease - epidemiology | Continental Population Groups - statistics & numerical data | Cohort Studies | Genome-wide association studies | Usage | Influence | Blood pressure | Genetic aspects | Diagnosis | Drinking of alcoholic beverages | Health aspects | Risk factors | Hypertension | Consumption | Health care | Medical research | Genes | Genomics | Genomes | Preventive medicine | Gene expression | Epidemiology | Loci | Blood | Genetic effects | Correlation analysis | Alcoholic beverages | Replication | Genetics | Bioinformatics | Public health | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Journal Article
by Clark, D.W and Okada, Y and Moore, K.H.S and Mason, D and Pirastu, N and Gandin, Ilaria and Mattsson, Hannele and Barnes, C.L.K and Lin, K and Zhao, J.H and Deelen, Patrick and Rohde, Rebecca and Schurmann, Claudia and Guo, Xiuqing and Giulianini, Franco and Zhang, W and Medina-Gomez, Carolina and Karlsson, R and Bao, Y and Bartz, T.M and Baumbach, Clemens and Biino, Ginevra and Bixley, M.J and Brumat, M and Chai, J.-F and Corre, Tanguy and Cousminer, Diana and Dekker, A.M and Eccles, D.A and Eijk, Kristel and Fuchsberger, C and Gao, H and Germain, Marine and Gordon, Scott D and de Haan, H.G and Harris, Sarah and Hofer, Edith and Huerta-Chagoya, Alicia and Igartua, C and Jansen, Iris and Jia, Y and Kacprowski, Tim and Karlsson, T and Kleber, Marcus and Li, S.A and Li-Gao, R and Mahajan, Anubha and Matsuda, K and Meidtner, Karina and Meng, W and Montasser, May E and Most, Peter and Munz, M and Nutile, T and Palviainen, T and Prasad, G and Prasad, R.B and Priyanka, T.D.S and Rizzi, F and Salvi, E and Sapkota, B.R and Shriner, Daniel and Skotte, L and Smart, M.C and Smith, Albert and Spek, Ashley and Spracklen, C.N and Strawbridge, Rona and Tajuddin, S.M and Trompet, Stella and Turman, C and Verweij, N and Viberti, C and Wang, L and Warren, Helen and Wootton, R.E and Yanek, Lisa and Yao, Jie and Yousri, N.A and Zhao, W and Adeyemo, A.A and Afaq, S and Aguilar-Salinas, C.A and Akiyama, M and Albert, M.L and Allison, M.A and Alver, Maris and Aung, Tin and Azizi, Joshan and Bentley, Amy and Boeing, Heiner and Boerwinkle, Eric and Borja, J.B and Borst, Gert and Bottinger, Erwin and Broer, L and Campbell, H and Chanock, Stephen and Chee, M.-L and Chen, G and ... and et al
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1
textabstractIn many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the... 
Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Turcot, V and Lu, YC and Highland, HM and Schurmann, C and Justice, AE and Fine, RS and Bradfield, JP and Esko, T and Giri, A and Graff, M and Guo, XQ and Hendricks, AE and Karaderi, T and Lempradl, A and Locke, AE and Mahajan, A and Marouli, E and Sivapalaratnam, S and Young, KL and Alfred, T and Feitosa, MF and Masca, NGD and Manning, AK and Medina-Gomez, C and Mudgal, P and Ng, MCY and Reiner, AP and Vedantam, S and Willems, SM and Winkler, TW and Abecasis, G and Aben, KK and Alam, DS and Alharthi, SE and Allison, M and Amouyel, P and Asselbergs, FW and Auer, PL and Balkau, B and Bang, LE and Barroso, I and Bastarache, L and Benn, M and Bergmann, S and Bielak, LF and Bluher, M and Boehnke, M and Boeing, H and Boerwinkle, E and Boger, CA and Bork-Jensen, J and Bots, ML and Bottinger, EP and Bowden, DW and Brandslund, I and Breen, G and Brilliant, MH and Broer, L and Brumat, M and Burt, AA and Butterworth, AS and Campbell, PT and Cappellani, S and Carey, DJ and Catamo, E and Caulfield, MJ and Chambers, JC and Chasman, DI and Chen, YDI and Chowdhury, R and Christensen, C and Chu, AY and Cocca, M and Collins, FS and Cook, JP and Corley, J and Galbany, JC and Cox, AJ and Crosslin, DS and Cuellar-Partida, G and D'Eustacchio, A and Danesh, J and Davies, G and Bakker, PIW and Groot, MCH and Mutsert, R and Deary, IJ and Dedoussis, G and Demerath, EW and Heijer, M and Hollander, AI and Ruijter, HM and Dennis, JG and Denny, JC and Di Angelantonio, E and Drenos, F and Du, MM and Dube, MP and Dunning, AM and Easton, DF and ... and INTERVAL Study and EPIC-CVD Consortium and EPIC InterAct Consortium and Global Lipids Genetic Consortium and GoT2D Genes Consortium and MAGIC Investigators and Understanding Soc Sci Grp and ReproGen Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium
NATURE GENETICS, ISSN 1061-4036, 07/2019, Volume 51, Issue 7, pp. 1191 - 1192
Journal Article