X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
oncology (14) 14
humans (11) 11
index medicus (10) 10
mutation (8) 8
neoplasms - genetics (6) 6
breast-cancer (5) 5
female (5) 5
gene expression (4) 4
genomics (4) 4
precision medicine - methods (4) 4
animals (3) 3
article (3) 3
breast cancer (3) 3
cancer (3) 3
genes (3) 3
melanoma (3) 3
neurodevelopmental disorders (3) 3
research (3) 3
abnormalities (2) 2
actionable genes (2) 2
activation (2) 2
adult (2) 2
aged (2) 2
analysis (2) 2
androgen receptor (2) 2
antineoplastic agents, hormonal - pharmacology (2) 2
antineoplastic agents, hormonal - therapeutic use (2) 2
autism (2) 2
biomarkers, tumor - genetics (2) 2
breast neoplasms - genetics (2) 2
breast neoplasms - metabolism (2) 2
cancer therapies (2) 2
care and treatment (2) 2
cell line, tumor (2) 2
clinical trial (2) 2
clinical trials (2) 2
colorectal-cancer (2) 2
de-novo mutations (2) 2
development and progression (2) 2
estrogen (2) 2
estrogen receptor alpha - metabolism (2) 2
expression (2) 2
feasibility studies (2) 2
gene expression profiling (2) 2
genetic aspects (2) 2
genomic sequencing (2) 2
health aspects (2) 2
high-throughput nucleotide sequencing - methods (2) 2
male (2) 2
medicine & public health (2) 2
metastasis (2) 2
mice (2) 2
middle aged (2) 2
neoplasms - diagnosis (2) 2
neoplasms - drug therapy (2) 2
neoplasms - therapy (2) 2
neurosciences (2) 2
patients (2) 2
phenotype (2) 2
phosphorylation (2) 2
precision medicine (2) 2
reproducibility of results (2) 2
resistance (2) 2
signal transduction - genetics (2) 2
somatic mutation (2) 2
somatic mutations (2) 2
tamoxifen (2) 2
tamoxifen - pharmacology (2) 2
tamoxifen - therapeutic use (2) 2
therapy (2) 2
transcriptional activation (2) 2
16p11.2 (1) 1
1st-line gefitinib (1) 1
acquired-resistance (1) 1
adolescent (1) 1
aged, 80 and over (1) 1
algorithms (1) 1
alpha (1) 1
alpha hinge-region (1) 1
alterations (1) 1
amygdala (1) 1
annotations (1) 1
antiestrogen resistance (1) 1
antineoplastic agents - pharmacology (1) 1
aromatase inhibitor (1) 1
articles (1) 1
autism spectrum disorder (1) 1
autism spectrum disorder - genetics (1) 1
autism spectrum disorder; databases, genetic; genetic predisposition to disease; genetic variation; humans; mosaicism; mutation, missense; zygote; neuroscience (1) 1
behavior (1) 1
binding-sites (1) 1
bioinformatics (1) 1
biomarkers (1) 1
biomarkers, tumor - metabolism (1) 1
bios3 (1) 1
blood diseases (1) 1
braf mutations (1) 1
brain (1) 1
breast neoplasms - pathology (1) 1
breast neoplasms - prevention & control (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Neuroscience, ISSN 1097-6256, 09/2017, Volume 20, Issue 9, pp. 1217 - 1224
Journal Article
Cancer Research, ISSN 0008-5472, 11/2017, Volume 77, Issue 21, pp. e123 - e126
High-throughput genomic and molecular profiling of tumors is emerging as an important clinical approach. Molecular profiling is increasingly being used to... 
Therapy | Navigation | Researchers | Profiling | Information processing | Oncology | Information retrieval | Cancer therapies | Tumors | Cancer
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 10/2013, Volume 141, Issue 3, pp. 375 - 384
Metastasis remains a major clinical problem in breast cancer. One family of genes previously linked with metastasis is the metastasis tumor-associated (MTA)... 
Medicine & Public Health | Rho | Oncology | Cytoskeleton | Breast cancer | Metastasis | MTA2 | MTA FAMILY | MAMMARY ADENOCARCINOMA | ALPHA | FAMILY PROTEINS | CELL-LINES | INVASION | GENE | ONCOLOGY | EXPRESSION | PROGRESSION | MOTILITY | Phenols | Development and progression | Analysis | Estrogen | Breast Cancer
Journal Article
by Salpietro, V and Dixon, CL and Guo, H and Bello, OD and Vandrovcova, J and Efthymiou, S and Maroofian, R and Heimer, G and Burglen, L and Valence, S and Torti, E and Hacke, M and Rankin, J and Tariq, H and Colin, E and Procaccio, V and Striano, P and Mankad, K and Lieb, A and Chen, S and Pisani, L and Bettencourt, C and Mannikko, R and Manole, A and Brusco, A and Grosso, E and Ferrero, GB and Armstrong-Moron, J and Gueden, S and Bar-Yosef, O and Tzadok, M and Monaghan, KG and Santiago-Sim, T and Person, RE and Cho, MT and Willaert, R and Yoo, Y and Chae, JH and Quan, YT and Wu, HD and Wang, TY and Bernier, RA and Xia, K and Blesson, A and Jain, M and Motazacker, MM and Jaeger, B and Schneider, AL and Boysen, K and Muir, AM and Myers, CT and Gavrilova, RH and Gunderson, L and Schultz-Rogers, L and Klee, EW and Dyment, D and Osmond, M and Parellada, M and Llorente, C and Gonzalez-Penas, J and Carracedo, A and Van Haeringen, A and Ruivenkamp, C and Nava, C and Heron, D and Nardello, R and Iacomino, M and Minetti, C and Skabar, A and Fabretto, A and Chez, M and Tsai, A and Fassi, E and Shinawi, M and Constantino, JN and De Zorzi, R and Fortuna, S and Kok, F and Keren, B and Bonneau, D and Choi, M and Benzeev, B and Zara, F and Mefford, HC and Scheffer, IE and Clayton-Smith, J and Macaya, A and Rothman, JE and Eichler, EE and Kullmann, DM and Houlden, H and Raspall-Chaure, M and Hanna, MG and Bugiardini, E and Hostettler, I and O'Callaghan, B and Khan, A and Cortese, A and O'Connor, E and Yau, WY and ... and SYNAPS Study Grp and SYNAPS Study Group
NATURE COMMUNICATIONS, ISSN 2041-1723, 07/2019, Volume 10, Issue 1, pp. 3094 - 16
Journal Article
by Martin-Brevet, Sandra and Rodríguez-Herreros, Borja and Nielsen, Jared A and Moreau, Clara and Modenato, Claudia and Maillard, Anne M and Pain, Aurélie and Richetin, Sonia and Jønch, Aia E and Qureshi, Abid Y and Zürcher, Nicole R and Conus, Philippe and Addor, Marie-Claude and Andrieux, Joris and Arveiler, Benoît and Baujat, Geneviève and Sloan-Béna, Frédérique and Belfiore, Marco and Bonneau, Dominique and Bouquillon, Sonia and Boute, Odile and Brusco, Alfredo and Busa, Tiffany and Caberg, Jean-Hubert and Campion, Dominique and Colombert, Vanessa and Cordier, Marie-Pierre and David, Albert and Debray, François-Guillaume and Delrue, Marie-Ange and Doco-Fenzy, Martine and Dunkhase-Heinl, Ulrike and Edery, Patrick and Fagerberg, Christina and Faivre, Laurence and Forzano, Francesca and Genevieve, David and Gérard, Marion and Giachino, Daniela and Guichet, Agnès and Guillin, Olivier and Héron, Delphine and Isidor, Bertrand and Jacquette, Aurélia and Jaillard, Sylvie and Journel, Hubert and Keren, Boris and Lacombe, Didier and Lebon, Sébastien and Le Caignec, Cédric and Lemaître, Marie-Pierre and Lespinasse, James and Mathieu-Dramart, Michèle and Mercier, Sandra and Mignot, Cyril and Missirian, Chantal and Petit, Florence and Pilekær Sørensen, Kristina and Pinson, Lucile and Plessis, Ghislaine and Prieur, Fabienne and Rooryck-Thambo, Caroline and Rossi, Massimiliano and Sanlaville, Damien and Schlott Kristiansen, Britta and Schluth-Bolard, Caroline and Till, Marianne and Van Haelst, Mieke and Van Maldergem, Lionel and Alupay, Hanalore and Aaronson, Benjamin and Ackerman, Sean and Ankenman, Katy and Anwar, Ayesha and Atwell, Constance and Bowe, Alexandra and Beaudet, Arthur L and Benedetti, Marta and Berg, Jessica and Berman, Jeffrey and Berry, Leandra N and Bibb, Audrey L and Blaskey, Lisa and Brennan, Jonathan and Brewton, Christie M and Buckner, Randy and Buckner, Randy L and Bukshpun, Polina and Burko, Jordan and Cali, Phil and Cerban, Bettina and Chang, Yishin and Cheong, Maxwell and Chow, Vivian and Chu, Zili and Chudnovskaya, Darina and Cornew, Lauren and Dale, Corby and Dell, John and Dempsey, Allison G and ... and 16p11 2 European Consorti and Simons Variation Individuals and Simons Variation in Individuals Project (VIP) Consortium and 16p11.2 European Consortium and Gillberg Neuropsychiatry Centre and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Gillbergcentrum and Sahlgrenska Academy
Biological Psychiatry, ISSN 0006-3223, 08/2018, Volume 84, Issue 4, pp. 253 - 264
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 11/2015, Volume 154, Issue 2, pp. 225 - 237
Tamoxifen (Tam) resistance represents a significant clinical problem in estrogen receptor (ER) α-positive breast cancer. We previously showed that decreased... 
Estrogen receptor | Medicine & Public Health | Androgen receptor | Oncology | Endocrine therapy resistance | Breast cancer | Tamoxifen | Epidermal growth factor receptor | PHOSPHORYLATION | PROTEIN-KINASE | CELL-PROLIFERATION | ESTROGEN-RECEPTOR | CROSS-TALK | GROWTH-FACTOR RECEPTOR | IN-VITRO | ONCOLOGY | PROSTATE-CANCER | RESISTANCE | RHO-GTPASES | Receptor, Epidermal Growth Factor - genetics | Cell Proliferation | Humans | Receptors, Androgen - metabolism | Transcriptional Activation | rho Guanine Nucleotide Dissociation Inhibitor alpha - metabolism | Drug Resistance, Neoplasm | Gene Expression Profiling | Breast Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Estrogen Receptor alpha - agonists | Antineoplastic Agents, Hormonal - therapeutic use | Estrogen Receptor alpha - metabolism | Female | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression | Antineoplastic Agents, Hormonal - pharmacology | Breast Neoplasms - genetics | MAP Kinase Signaling System - drug effects | Receptors, Androgen - genetics | Breast Neoplasms - pathology | Tamoxifen - therapeutic use | Tamoxifen - pharmacology | Cell Line, Tumor | Protein Binding | Index Medicus | endocrine therapy resistance | breast cancer | androgen receptor | estrogen receptor | epidermal growth factor receptor | tamoxifen
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 11/2017, Volume 77, Issue 21, pp. E123 - E126
High-throughput genomic and molecular profiling of tumors is emerging as an important clinical approach. Molecular profiling is increasingly being used to... 
DATABASE | ONCOLOGY | DRUGS | Evidence-Based Medicine - methods | Medical Oncology - methods | Neoplasms - therapy | Reproducibility of Results | Neoplasms - genetics | Humans | Neoplasms - diagnosis | Internet | Data Mining - methods | Molecular Targeted Therapy - methods | Precision Medicine - methods | Index Medicus
Journal Article
Cancer research, ISSN 0008-5472, 11/2017, Volume 77, Issue 21, pp. e123 - e126
High throughput genomic and molecular profiling of tumors is emerging as an important clinical approach. Molecular profiling is increasingly being utilized to... 
Precision Oncology | Targeted Therapy | Bioinformatics
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 24, pp. 20099 - 20110
PURPOSEWe determined the frequency of recurrent hotspot mutations in 46 cancer-related genes across tumor histologies in patients with advanced... 
Genomic sequencing | Actionable genes | Index Medicus
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 04/2011, Volume 103, Issue 7, pp. 538 - 552
Background Estrogen receptor (ER) alpha is a successful therapeutic target in breast cancer, but patients eventually develop resistance to antiestrogens such... 
BREAST-CANCER | INDEPENDENT GROWTH | LUNG METASTASIS | AROMATASE INHIBITOR | ACTIVATION | ONCOLOGY | PHOSPHORYLATION | SERINE 305 | ANTIESTROGEN RESISTANCE | EXPRESSION | METASTASIS SUPPRESSOR GENE | Immunohistochemistry | Humans | Transcriptional Activation | Immunoblotting | Secondary Prevention - methods | rho-Specific Guanine Nucleotide Dissociation Inhibitors | Time Factors | Odds Ratio | Repressor Proteins - metabolism | Tumor Stem Cell Assay | Histone Deacetylases - genetics | Down-Regulation | Repressor Proteins - genetics | Signal Transduction - genetics | Random Allocation | Breast Neoplasms - prevention & control | Estrogen Receptor alpha - drug effects | Drug Resistance, Neoplasm - genetics | Phenotype | Estrogen Antagonists - therapeutic use | Signal Transduction - drug effects | Mice, Nude | rho GTP-Binding Proteins - metabolism | Cell Line, Tumor | Guanine Nucleotide Dissociation Inhibitors - genetics | Mice | Enzyme Activation | Selective Estrogen Receptor Modulators - pharmacology | RNA, Small Interfering - metabolism | Immunoprecipitation | Guanine Nucleotide Dissociation Inhibitors - metabolism | Gene Expression Regulation, Neoplastic | Estrogen Antagonists - pharmacology | Transplantation, Heterologous | Breast Neoplasms - metabolism | Antineoplastic Agents, Hormonal - therapeutic use | Estrogen Receptor alpha - metabolism | Female | Retrospective Studies | Genome-Wide Association Study | Antineoplastic Agents, Hormonal - pharmacology | Neoplasm Recurrence, Local - metabolism | Neoplasm Recurrence, Local - prevention & control | Gene Silencing | Histone Deacetylases - metabolism | Animals | Plasmids | Tamoxifen - therapeutic use | Tamoxifen - pharmacology | Protein Array Analysis | rho Guanine Nucleotide Dissociation Inhibitor alpha | Drug Resistance, Neoplasm - drug effects | Index Medicus
Journal Article