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Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 12, pp. e8152 - e8152
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs).... 
PROGENITOR CELLS | MACULAR TRANSLOCATION | RCS RAT | SUBRETINAL TRANSPLANTATION | VISUAL FUNCTION | RPE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | AUTOLOGOUS TRANSPLANTATION | HUMAN FIBROBLASTS | PHOTORECEPTOR DEGENERATION | Biomarkers - metabolism | Epithelial Cells - transplantation | Immunohistochemistry | Cell Polarity | Photoreceptor Cells, Vertebrate - ultrastructure | Retinal Pigment Epithelium - transplantation | Cell Survival | Humans | Proto-Oncogene Proteins c-fos - metabolism | Retinal Diseases - therapy | Rats | Photoreceptor Cells, Vertebrate - cytology | Macrophages - cytology | Vision, Ocular - physiology | Animals | Retinal Pigment Epithelium - ultrastructure | Cell Shape | Retinal Diseases - pathology | Cell Differentiation | Epithelial Cells - cytology | Induced Pluripotent Stem Cells - cytology | Retinal Diseases - physiopathology | Phagocytosis | Retinal Pigment Epithelium - cytology | Macular degeneration | Epithelium | Embryonic stem cells | Health aspects | Monomolecular films | Transformation | Transcription factors | Pathogenesis | Embryo cells | Stem cell transplantation | Retina | Transplantation | Retinal pigment epithelium | Visual perception | Engineering | Allografts | Fibroblasts | Degeneration | Age | Medical personnel | Cell survival | Developmental biology | Medical treatment | Gene expression | Somatic cells | Stem cells | Photoreceptors | Pluripotency | Index Medicus
Journal Article
Stem Cells, ISSN 1066-5099, 10/2009, Volume 27, Issue 10, pp. 2427 - 2434
Human induced pluripotent stem cells (iPSCs) have great promise for cellular therapy, but it is unclear if they have the same potential as human embryonic stem... 
Retinal pigmented epithelium | Age-related macular degeneration | Induced pluripotent stem cells | Retinitis pigmentosa | ISOMEROHYDROLASE | ROD OUTER SEGMENTS | PHAGOCYTOSIS | MACULAR DEGENERATION | retinal pigmented epithelium | IPS CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | MICROSOMAL PROTEIN | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | retinitis pigmentosa | induced pluripotent stem cells | RPE CELLS | DIFFERENTIATION | HEMATOLOGY | age-related macular degeneration | EYE DEVELOPMENT | EXPRESSION | Retinal Pigment Epithelium - metabolism | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Nerve Tissue Proteins - analysis | Retinal Diseases - therapy | RNA, Messenger - analysis | Retinal Rod Photoreceptor Cells - metabolism | RNA, Messenger - metabolism | SOXB1 Transcription Factors - metabolism | SOXB1 Transcription Factors - pharmacology | Homeodomain Proteins - pharmacology | Cell Differentiation - physiology | Integrin alphaV - metabolism | Biomarkers - metabolism | Cell Line | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Biomarkers - analysis | Octamer Transcription Factor-3 - pharmacology | Phagocytosis - physiology | Regeneration - physiology | Nerve Tissue Proteins - metabolism | Pluripotent Stem Cells - metabolism | Phenotype | Regeneration - drug effects | Cell Differentiation - drug effects | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - drug effects | Retinal Rod Photoreceptor Cells - cytology | Cell Polarity - physiology | Brain Tissue Transplantation - methods | Retinal Pigment Epithelium - cytology | Index Medicus
Journal Article
STEM CELLS Translational Medicine, ISSN 2157-6564, 05/2013, Volume 2, Issue 5, pp. 384 - 393
Although protocols to generate retinal pigmented epithelium (RPE) from human pluripotent stem cells have become more efficient since the first report in 2004,... 
Differentiation | Embryonic stem cells | Pluripotent stem cells | Retinal pigmented epithelium | Induced pluripotent stem cells | Cellular therapy | PATHWAYS | TRANSLOCATION | TRANSCRIPTION | MACULAR DEGENERATION | DEATH | INDUCTION | CULTURE | CELL & TISSUE ENGINEERING | ROCK INHIBITOR | DISEASE | GROWTH-FACTOR | Cell Line | Retinal Pigment Epithelium - metabolism | Pluripotent Stem Cells - cytology | Humans | RNA, Messenger - genetics | Cells, Cultured | Visual Fields - drug effects | RNA, Messenger - metabolism | Cell Lineage - drug effects | Gene Expression Regulation - drug effects | Pluripotent Stem Cells - metabolism | Cell Differentiation - genetics | Pyrroles - pharmacology | Activins - pharmacology | Time Factors | Vasoactive Intestinal Peptide - pharmacology | Cell Differentiation - drug effects | Pluripotent Stem Cells - drug effects | Cell Proliferation - drug effects | Niacinamide - pharmacology | Retinal Pigment Epithelium - cytology | Retinal Pigment Epithelium - drug effects | Phenotypes | Data analysis | Clinical trials | Retina | Transplantation | Research | Epithelium | Cell differentiation | Experiments | Retinal pigment epithelium | Cell adhesion & migration | Macular degeneration | Efficiency | Stem cells | Fibroblasts | Growth factors | Pluripotency | Index Medicus | Protocols and Manufacturing for Cell-Based Therapies
Journal Article
STEM CELLS Translational Medicine, ISSN 2157-6564, 09/2014, Volume 3, Issue 9, pp. 1066 - 1078
Journal Article
Journal of Tissue Engineering and Regenerative Medicine, ISSN 1932-6254, 08/2013, Volume 7, Issue 8, pp. 642 - 653
Journal Article
Journal Article
Nature Methods, ISSN 1548-7091, 10/2006, Volume 3, Issue 10, pp. 777 - 779
Large-scale RNA interference (RNAi)-based analyses, very much as other 'omic' approaches, have inherent rates of false positives and negatives. The variability... 
BIOCHEMICAL RESEARCH METHODS | Databases, Genetic - standards | Phenotype | RNA Interference | Genetic Testing - standards | Sensitivity and Specificity | Risk | False Positive Reactions
Journal Article
Journal Article