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Nature, ISSN 0028-0836, 08/2019, Volume 572, Issue 7771, pp. 1 - 2
Rheumatoid arthritis is an immunemediated disease associated with inflammation and the destruction of the cartilage and bone in joints, and macrophages have a... 
Genes | Neutrophils | Arthritis | Inflammation | Ribonucleic acid--RNA | Gene expression | Macrophages | Joint diseases | Proteins | Cartilage | Rheumatoid arthritis | Joints (anatomy) | Fibroblasts | Aging | Genetic engineering
Journal Article
Nature, ISSN 0028-0836, 08/2019, Volume 572, Issue 7771, pp. 590 - 592
Journal Article
RHEUMATOLOGY, ISSN 1462-0324, 06/2017, Volume 56, Issue 6, pp. 863 - 864
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 02/2018, Volume 20, Issue 1, pp. 19 - 2
Journal Article
Rheumatology (United Kingdom), ISSN 1462-0324, 06/2017, Volume 56, Issue 6, pp. 863 - 864
Journal Article
Nature reviews. Rheumatology, ISSN 1759-4790, 01/2019, Volume 15, Issue 1, pp. 61 - 61
In the originally published version of this article, the acknowledgements and affiliations contained errors. In the acknowledgements, "NIHR Oxford and... 
Medicine, Experimental | Medical research | Inflammation | Health aspects
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2017, Volume 76, Issue Suppl 1, p. A10
BackgroundThe inappropriate recruitment and retention of T-cells into the joint is a cardinal feature of RA, yet the molecular mechanisms underpinning this... 
Journal Article
Immunology Letters, ISSN 0165-2478, 2011, Volume 138, Issue 1, pp. 12 - 14
Abstract One of the most important but as yet unanswered questions in inflammation research is not why inflammation occurs (we all get episodes of self... 
Allergy and Immunology | RHEUMATOID SYNOVIUM | MECHANISM | TISSUE | PATTERNS | ACCUMULATION | INDUCTION | SKIN | IMMUNOLOGY | CONTRIBUTES | EXPRESSION | T-CELLS | Fibroblasts - immunology | Inflammation - immunology | Chronic Disease | Humans | Analysis | Inflammation | Cell survival | Lymphocytes | stromal cells | Effector cells | Fibroblasts | Leukocytes | Lymphoid tissue | Self | Stress | Immune system
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2017, Volume 76, Issue Suppl 1, p. A51
BackgroundStromal cells are key effector cells in tissue inflammation and damage. Despite their importance these cells are yet to be targeted therapeutically.... 
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2017, Volume 76, Issue Suppl 1, p. A66
BackgroundDuring synovial inflammation, platelets and their associated microparticles escape from the synovial microvasculature and provide pro-inflammatory... 
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2017, Volume 76, Issue Suppl 1, p. A53
BackgroundAberrant activation of synovial fibroblasts (SFs) is a key determinant in the pathogenesis of rheumatoid arthritis (RA). We aimed to produce a... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 29, p. E6826
Antibody-secreting plasma cells (PCs) arise rapidly during adaptive immunity to control infections. The early PCs are retained within the reactive lymphoid... 
Plasma | CXCL12 protein | Leukocyte migration | Homeostasis | Infections | Macrophages | Adaptive control | Immunity | Lymph nodes | APRIL protein | Interleukin 6 | Cords | Fibroblasts | Immunity (humoral) | Localization | Lymphatic system | Immunoglobulins | Myeloid cells | Cell survival | Medulla | Adaptive immunity | Survival | BLyS protein | Stromal cells | Plasma cells | Cell migration | Niches | Lymph
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2017, Volume 76, Issue Suppl 1, pp. A10 - A11
BackgroundThe inappropriate recruitment and retention of T-cells into the joint is a cardinal feature of RA, yet the molecular mechanisms underpinning this... 
Journal Article
Nature Reviews Rheumatology, ISSN 1759-4790, 01/2016, Volume 12, Issue 1, pp. 63 - 68
Cytokine-mediated pathways are central to the pathogenesis of rheumatoid arthritis (RA). The purpose of this short Opinion article is to briefly overview the... 
PATHOGENESIS | INFLAMMATORY DISEASES | AUTOIMMUNE-DISEASES | THERAPEUTIC TARGET | PHASE-II | T-CELL | RHEUMATOLOGY | FIBROBLASTS | IL-6 | Adaptive Immunity | Arthritis, Rheumatoid - metabolism | Cytokines - metabolism | Arthritis, Rheumatoid - drug therapy | Humans | Arthritis, Rheumatoid - immunology | Antirheumatic Agents - therapeutic use
Journal Article
Annual Review of Immunology, ISSN 0732-0582, 01/2015, Volume 33, pp. 715 - 745
Inflammation is an unstable state. It either resolves or persists. Why inflammation persists and the factors that define tissue tropism remain obscure.... 
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2013, Volume 72, Issue Suppl 1, pp. A1 - A1
Background and Objectives Fibroblasts actively regulate the recruitment of leukocytes by endothelial cells (EC), acting in a pro- or anti-inflammatory manner... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2015, Volume 112, Issue 43, p. E5815
  Constitutive resistance to cell death induced by inflammatory stimuli activating the extrinsic pathway of apoptosis is a key feature of vascular endothelial... 
Signal transduction | Transcription factors | Biochemistry | Gene expression | Endothelium | Apoptosis
Journal Article
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