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1. Colorectal adenomatous polyposis syndromes: Genetic determinism, clinical presentation and recommendations for care
by Buecher, Bruno
Bulletin du cancer, 02/2016, Volume 103, Issue 2, p. 199
Colorectal adenomatous polyposis constitutes a diverse group of disorders with different modes of inheritance. Molecular diagnosis of this condition has become... 
Stomach Neoplasms - genetics | Genetic Predisposition to Disease | Genetic Testing | Colorectal Neoplasms - genetics | Humans | Prenatal Diagnosis | DNA Glycosylases - genetics | Brain Neoplasms - genetics | Genes, APC | Adenomatous Polyposis Coli - complications | Phenotype | Mosaicism | Neoplastic Syndromes, Hereditary - genetics | Adenomatous Polyposis Coli - therapy | Genetic Determinism | Mutation | Adenomatous Polyposis Coli - genetics | Sequence Analysis, DNA - methods | Adenomatous Polyposis Coli - diagnosis
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2. Colorectal adenomatous polyposis syndromes: Genetic determinism, clinical presentation and recommendations for care
by Buecher, Bruno
Bulletin du Cancer, ISSN 0007-4551, 02/2016, Volume 103, Issue 2, pp. 199 - 209
Colorectal adenomatous polyposis constitutes a diverse group of disorders with different modes of inheritance. Molecular diagnosis of this condition has become... 
Genetic predisposition | Colorectal polyposis | Colorectal cancer | CANCER SYNDROMES | GERMLINE | GUIDELINES | FAP | APC | ONCOLOGY | ECTODERMAL DYSPLASIA | MUTATIONS | MUTYH-ASSOCIATED POLYPOSIS | PREDISPOSE | MOSAICISM
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3. Full Text Cancer Risks Associated With Germline Mutations in MLH1, MSH2, and MSH6 Genes in Lynch Syndrome
by Bonadona, Valérie and Bonaïti, Bernard and Olschwang, Sylviane and Grandjouan, Sophie and Huiart, Laetitia and Longy, Michel and Guimbaud, Rosine and Buecher, Bruno and Bignon, Yves-Jean and Caron, Olivier and Colas, Chrystelle and Noguès, Catherine and Lejeune-Dumoulin, Sophie and Olivier-Faivre, Laurence and Polycarpe-Osaer, Florence and Nguyen, Tan Dat and Desseigne, Françoise and Saurin, Jean-Christophe and Berthet, Pascaline and Leroux, Dominique and Duffour, Jacqueline and Manouvrier, Sylvie and Frébourg, Thierry and Sobol, Hagay and Lasset, Christine and Bonaïti-Pellié, Catherine and French Cancer Genetics Network, for the and French Canc Genetics Network and French Cancer Genetics Network
JAMA, ISSN 0098-7484, 06/2011, Volume 305, Issue 22, pp. 2304 - 2310
CONTEXT Providing accurate estimates of cancer risks is a major challenge in the clinical management of Lynch syndrome. OBJECTIVE To estimate the age-specific... 
HNPCC | MEDICINE, GENERAL & INTERNAL | CUMULATIVE LIFETIME INCIDENCE | GRL METHOD | NONPOLYPOSIS COLORECTAL-CANCER | ESTIMATING PENETRANCE | CARRIERS | PROVEN MUTATIONS | 121 FAMILIES | AGE-OF-ONSET | ENDOMETRIAL CANCER | MutL Protein Homolog 1 | Age Factors | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Incidence | Ovarian Neoplasms - genetics | Young Adult | Endometrial Neoplasms - genetics | Aged, 80 and over | Germ-Line Mutation | Adult | Female | Nuclear Proteins - genetics | Colorectal Neoplasms - epidemiology | France - epidemiology | Genetic Predisposition to Disease | Risk Assessment | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Genotype | MutS Homolog 2 Protein - genetics | Endometrial Neoplasms - epidemiology | DNA-Binding Proteins - genetics | Ovarian Neoplasms - epidemiology | Adaptor Proteins, Signal Transducing - genetics | Aged | Genetic aspects | Research | Gene mutations | Risk factors | Colorectal cancer | Cancer | Bacteria | Mutation | Womens health | Ovarian cancer | Endometrial Neoplasms | Life Sciences | Colorectal Neoplasms | Ovarian Neoplasms | France | DNA-Binding Proteins | MutS Homolog 2 Protein | Colorectal Neoplasms, Hereditary Nonpolyposis | Nuclear Proteins | Adaptor Proteins, Signal Transducing
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4. Full Text Preoperative Radiotherapy With or Without Concurrent Fluorouracil and Leucovorin in T3-4 Rectal Cancers: Results of FFCD 9203
by Jean-Pierre Gérard and Thierry Conroy and Franck Bonnetain and Olivier Bouché and Olivier Chapet and Marie-Thérèse Closon-Dejardin and Michel Untereiner and Bernard Leduc and Éric Francois and Jean Maurel and Jean-François Seitz and Bruno Buecher and Rémy Mackiewicz and Michel Ducreux and Laurent Bedenne
Journal of Clinical Oncology, ISSN 0732-183X, 10/2006, Volume 24, Issue 28, pp. 4620 - 4625
Purpose In 1992, preoperative radiotherapy was considered in France as the standard treatment for T3-4 rectal cancers. The present randomized trial compares... 
SURGERY | SPHINCTER-PRESERVATION | COMBINED-MODALITY THERAPY | ONCOLOGY | RANDOMIZED-TRIAL | ADJUVANT TREATMENT | CHEMORADIOTHERAPY | ACUTE TOXICITY | RADIATION | TOTAL MESORECTAL EXCISION | CHEMOTHERAPY | Recurrence | Rectal Neoplasms - surgery | Humans | Middle Aged | Male | Vitamin B Complex - pharmacology | Adenocarcinoma - drug therapy | Rectal Neoplasms - radiotherapy | Radiotherapy - methods | Aged, 80 and over | Adult | Antimetabolites, Antineoplastic - pharmacology | Female | Aged | Fluorouracil - pharmacology | Leucovorin - pharmacology | Rectal Neoplasms - drug therapy | Adenocarcinoma - radiotherapy | Adenocarcinoma - surgery
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5. Full Text Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
by Bojesen, Stig E and Pooley, Karen A and Johnatty, Sharon E and Beesley, Jonathan and Michailidou, Kyriaki and Tyrer, Jonathan P and Edwards, Stacey L and Pickett, Hilda A and Shen, Howard C and Smart, Chanel E and Hillman, Kristine M and Mai, Phuong L and Lawrenson, Kate and Stutz, Michael D and Lu, Yi and Karevan, Rod and Woods, Nicholas and Johnston, Rebecca L and French, Juliet D and Chen, Xiaoqing and Weischer, Maren and Nielsen, Sune F and Maranian, Melanie J and Ghoussaini, Maya and Ahmed, Shahana and Baynes, Caroline and Bolla, Manjeet K and Wang, Qin and Dennis, Joe and McGuffog, Lesley and Barrowdale, Daniel and Lee, Anew and Healey, Sue and Lush, Michael and Tessier, Daniel C and Vincent, Daniel and Bacot, Françis and Vergote, Ignace and Lambrechts, Sanina and Despierre, Evelyn and Risch, Harvey A and González-Neira, Anna and Rossing, Mary Anne and Pita, Guillermo and Doherty, Jennifer A and Alvarez, Nuria and Larson, Melissa C and Fridley, Brooke L and Schoof, Nils and Chang-Claude, Jenny and Cicek, Mine S and Peto, Julian and Kalli, Kimberly R and Broeks, Annegien and Armasu, Sebastian M and Schmidt, Marjanka K and Braaf, Linde M and Winterhoff, Boris and Nevanlinna, Heli and Konecny, Gottfried E and Lambrechts, Diether and Rogmann, Lisa and Guénel, Pascal and Teoman, Attila and Milne, Roger L and Garcia, Joaquin J and Cox, Angela and Shridhar, Vijayalakshmi and Burwinkel, Barbara and Marme, Frederik and Hein, Rebecca and Sawyer, Elinor J and Haiman, Christopher A and Wang-Gohrke, Shan and Anulis, Irene L and Moysich, Kirsten B and Hopper, John L and Odunsi, Kunle and Lindblom, Annika and Giles, Graham G and Brenner, Hermann and Simard, Jacques and Lurie, Galina and Fasching, Peter A and Carney, Michael E and Radice, Paolo and Wilkens, Lynne R and Swerdlow, Anthony and Goodman, Marc T and Brauch, Hiltrud and Garcia-Closas, Montserrat and Hillemanns, Peter and Winqvist, Robert and Dürst, Matthias and Devilee, Peter and Runnebaum, Ingo and Jakubowska, Anna and Lubinski, Jan and Mannermaa, Arto and Butzow, Ralf and ... and Gene Environm Interactimi Breast and Kathleen Cuningham Fdn Consortium and Australian Ovarian Canc Study and Epidemiological Study BRCA1 and Hereditary Breast Ovarian Canc Res and Genetic Modifiers Canc Risk BRCA1 and Australian Canc Study and Swedish Breast Canc Study SWE-BRCA and The Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) and Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO) and Gene Environment Interaction and Breast Cancer (GENICA) and Swedish Breast Cancer Study (SWE-BRCA) and Epidemiological study of BRCA1 & BRCA2 Mutation Carriers (EMBRACE) and Australian Ovarian Cancer Study and Australian Cancer Study and Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab) and Medicinska fakulteten and Umeå universitet and Institutionen för strålningsvetenskaper
Nature genetics, ISSN 1061-4036, 2013, Volume 45, Issue 4, pp. 371 - 384
TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of multiple cancers. Using the Illumina custom genotyping array iCOGs, we... 
BUCCAL CELLS | GENETIC-VARIATION | COMMON VARIANTS | TERT-CLPTM1L LOCUS | REVERSE-TRANSCRIPTASE | SEQUENCE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | POLYMORPHISM | FIBROBLASTS | GENOME-WIDE ASSOCIATION | Breast cancer | Genetic aspects | Research | Single nucleotide polymorphisms | Risk factors | Ovarian cancer | Genetics | Mutation | Càncer de mama | Càncer d'ovari | Telòmer | Telomere | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
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6. Full Text CDH1 germline mutations and the hereditary diffuse gastric and lobular breast cancer syndrome: a multicentre study
by Benusiglio, Patrick R and Malka, David and Rouleau, Etienne and De Pauw, Antoine and Buecher, Bruno and Noguès, Catherine and Fourme, Emmanuelle and Colas, Chrystelle and Coulet, Florence and Warcoin, Mathilde and Grandjouan, Sophie and Sezeur, Alain and Laurent-Puig, Pierre and Molière, Diane and Tlemsani, Camille and Di Maria, Marina and Byrde, Veronique and Delaloge, Suzette and Blayau, Martine and Caron, Olivier
Journal of Medical Genetics, ISSN 0022-2593, 07/2013, Volume 50, Issue 7, pp. 486 - 489
Introduction CDH1 predisposes primarily to diffuse gastric cancer (DGC). Multiple DGC cases in a family, DGC at a young age in an individual or the combination... 
GASTRECTOMY | FAMILIES | GUIDELINES | GENETICS & HEREDITY | EARLY-ONSET | RISK | E-CADHERIN MUTATIONS | BRCA1 | CARRIERS | CLINICAL MANAGEMENT | Stomach Neoplasms - genetics | Genetic Predisposition to Disease | Breast Neoplasms - genetics | Humans | Germ-Line Mutation | Adult | Female | Cadherins - genetics | Case-Control Studies | Syndrome
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7. Full Text HPV circulating tumor DNA to monitor the efficacy of anti‐PD‐1 therapy in metastatic squamous cell carcinoma of the anal canal: A case report
by Cabel, Luc and Bidard, François‐Clément and Servois, Vincent and Cacheux, Wulfran and Mariani, Pascale and Romano, Emanuela and Minsat, Mathieu and Bieche, Ivan and Farkhondeh, Fereshteh and Jeannot, Emmanuelle and Buecher, Bruno
International Journal of Cancer, ISSN 0020-7136, 10/2017, Volume 141, Issue 8, pp. 1667 - 1670
Squamous cell carcinoma of the anal canal (SCCA) is a rare HPV‐associated cancer with limited sensitivity to standard chemotherapy. In a phase 2 study,... 
anal canal | nivolumab | human papillomavirus | immunotherapy | circulating tumor DNA | ONCOLOGY | CANCER | Carcinoma, Squamous Cell - blood | Carcinoma, Squamous Cell - virology | Humans | Antibodies, Monoclonal - therapeutic use | Anus Neoplasms - virology | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Carcinoma, Squamous Cell - immunology | Papillomaviridae - genetics | DNA, Viral - blood | Anus Neoplasms - immunology | Carcinoma, Squamous Cell - drug therapy | Anus Neoplasms - blood | Anus Neoplasms - drug therapy | Female | Aged | Programmed Cell Death 1 Receptor - immunology | DNA, Viral - genetics | Clinical Trials, Phase II as Topic | Chemotherapy | Squamous cell carcinoma | Immunotherapy | DNA | Metastasis | Papillomavirus infections | Cancer | Effectiveness | Risk groups | PD-1 protein | Health risks | Viruses | Infections | Cancer therapies | Patients | Metastases | Polymerase chain reaction | Sensitivity | Human papillomavirus | Immune checkpoint | Biomarkers | Infiltration | Bioindicators | Kinetics | Deoxyribonucleic acid--DNA
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8. Full Text Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
by Phelan, Catherine M and Kuchenbaecker, Karoline B and Tyrer, Jonathan P and Kar, Siddhartha P and Lawrenson, Kate and Winham, Stacey J and Dennis, Joe and Pirie, Ailith and Riggan, Marjorie J and Chornokur, Ganna and Earp, Madalene A and Lyra, Paulo C and Lee, Janet M and Coetzee, Simon and Beesley, Jonathan and McGuffog, Lesley and Soucy, Penny and Dicks, Ed and Lee, Anew and Barrowdale, Daniel and Lecarpentier, Julie and Leslie, Goska and Aalfs, Cora M and Aben, Katja K. H and Adams, Marcia and Adlard, Julian and Anulis, Irene L and Anton-Culver, Hoda and Antonenkova, Natalia and Aravantinos, Gerasimos and Arnold, Norbert and Arun, Banu K and Arver, Brita and Azzollini, Jacopo and Balmaña, Judith and Banerjee, Susana N and Barjhoux, Laure and Barkardottir, Rosa B and Bean, Yukie and Beckmann, Matthias W and Beeghly-Fadiel, Alicia and Benitez, Javier and Bermisheva, Marina and Bernardini, Marcus Q and Birrer, Michael J and Bjorge, Line and Black, Amanda and Blankstein, Kenneth and Blok, Marinus J and Bodelon, Clara and Bogdanova, Natalia and Bojesen, Anders and Bonanni, Bernardo and Borg, Åke and Bradbury, Angela R and Brenton, James D and Brewer, Carole and Brinton, Louise and Broberg, Per and Brooks-Wilson, Angela and Bruinsma, Fiona and Brunet, Joan and Buecher, Bruno and Butzow, Ralf and Buys, Sauna S and Caldes, Trinidad and Caligo, Maria A and Campbell, Ian and Cannioto, Rikki and Carney, Michael E and Cescon, Terence and Chan, Salina B and Chang-Claude, Jenny and Chanock, Stephen and Chen, Xiao Qing and Chiew, Yoke-Eng and Chiquette, Jocelyne and Chung, Wendy K and Claes, Kathleen B. M and Conner, Thomas and Cook, Linda S and Cook, Jackie and Cramer, Daniel W and Cunningham, Julie M and D'Aloisio, Aimee A and Daly, Mary B and Damiola, Francesca and Damirovna, Sakaeva Dina and Dansonka-Mieszkowska, Agnieszka and Dao, Fanny and Davidson, Rosemarie and Defazio, Anna and Delnatte, Capucine and Doheny, Kimberly F and Diez, Orland and Ding, Yuan Chun and Doherty, Jennifer Anne and Domchek, Susan M and Dorfling, Cecilia M and Dörk, Thilo and ... and KConFab Investigators and EMEMBRACE Study and GEMO Study Collaborators and OPAL Study Grp and AOCS Study Grp and HEBON Study and AOCS study group and EMBRACE Study and OPAL study group and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Ortopedi and Uppsala universitet and Institutionen för kirurgiska vetenskaper
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 5, pp. 680 - 691
To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping... 
BREAST-CANCER | COMMON VARIANTS | METAANALYSIS | CLEAR-CELL | ALGORITHM | GENETICS & HEREDITY | RISK | ASSOCIATION | CARCINOMA | ENDOMETRIOSIS | TELOMERE LENGTH | Neoplasms, Glandular and Epithelial - pathology | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Meta-Analysis as Topic | Humans | Risk Factors | Genetic Loci - genetics | Ovarian Neoplasms - pathology | Genotype | Ovarian Neoplasms - genetics | BRCA1 Protein - genetics | Neoplasms, Glandular and Epithelial - genetics | Telomere-Binding Proteins - genetics | Alleles | Carcinoma, Ovarian Epithelial | Female | Polymorphism, Single Nucleotide | Mutation | BRCA2 Protein - genetics | Genetic susceptibility | Physiological aspects | Genetic aspects | Single nucleotide polymorphisms | Identification and classification | Health aspects | Risk factors | Ovarian cancer | Carriers | Medical research | Ovarian carcinoma | Genes | Gene regulation | Genomes | Breast cancer | Loci | Cancer | Life Sciences | Human health and pathology | Genetics | Medical and Health Sciences | Medicin och hälsovetenskap
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9. Full Text Morphology and genomic hallmarks of breast tumours developed by ATM deleterious variant carriers
by Renault, Anne-Laure and Mebirouk, Noura and Fuhrmann, Laetitia and Bataillon, Guillaume and Cavaciuti, Eve and Le Gal, Dorothée and Girard, Elodie and Popova, Tatiana and La Rosa, Philippe and Beauvallet, Juana and Eon-Marchais, Séverine and Dondon, Marie-Gabrielle and d'Enghien, Catherine Dubois and Laugé, Anthony and Chemlali, Walid and Raynal, Virginie and Labbé, Martine and Bièche, Ivan and Baulande, Sylvain and Bay, Jacques-Olivier and Berthet, Pascaline and Caron, Olivier and Buecher, Bruno and Faivre, Laurence and Fresnay, Marc and Gauthier-Villars, Marion and Gesta, Paul and Janin, Nicolas and Lejeune, Sophie and Maugard, Christine and Moutton, Sébastien and Venat-Bouvet, Laurence and Zattara, Hélène and Fricker, Jean-Pierre and Gladieff, Laurence and Coupier, Isabelle and Chenevix-Trench, Georgia and Hall, Janet and Vincent-Salomon, Anne and Stoppa-Lyonnet, Dominique and Andrieu, Nadine and Lesueur, Fabienne and Mazoyer, Sylvie and Damiola, Francesca and Barjhoux, Laure and de Pauw, Antoine and Dahan, Karin and Combès, Audrey and Vennin, Philippe and Adenis, Claude and Longy, Michel and Lortholary, Alain and Gilbert-Dussardier, Brigitte and Jacquot, Caroline and Frenay, Marc and Leroux, Dominique and Lesca, Gaétan and Chompret, Agnès and Lasset, Christine and Lespinasse, James and Tchiknavorian, Xavier and Dugast, Catherine and Martin-Coignard, Dominique and Chiesa, Jean and Nizard, Sonia and Leheup, Bruno and Collignon, Patrick and Demange, Liliane and Rohlrich, Pierre and Fellmann, Florence and Pellier, Isabelle and Tinat, Julie and GENESIS and kConFab and CoF-AT
Breast Cancer Research, ISSN 1465-5411, 04/2018, Volume 20, Issue 1, pp. 28 - 18
The ataxia telangiectasia mutated (ATM) gene is a moderate-risk breast cancer susceptibility gene; germline loss-of-function variants are found in up to 3% of... 
Pathology | Copy number | Breast tumour | Loss of heterozygosity | OncoScan array | ATM | Genetic instability | Genomic signature | Breast Neoplasms, Male - genetics | Genetic Testing | Genomics | Humans | Middle Aged | Male | DNA Repair - genetics | Germ-Line Mutation - genetics | Loss of Heterozygosity - genetics | DNA Damage - genetics | Adult | Female | Ataxia Telangiectasia - complications | Breast Neoplasms - classification | Genetic Predisposition to Disease | Breast Neoplasms, Male - complications | BRCA1 Protein - genetics | Breast Neoplasms - complications | Breast Neoplasms, Male - classification | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Ataxia Telangiectasia - pathology | Ataxia Telangiectasia - genetics | Aged | Breast Neoplasms, Male - pathology | Ataxia Telangiectasia Mutated Proteins - genetics | BRCA2 Protein - genetics | Sequence Deletion - genetics | Care and treatment | Usage | Copy number variations | Analysis | DNA damage | Ataxia telangiectasia | Breast cancer | Genetic aspects | Research | Risk factors | Genetic screening | Life Sciences | Hematology | Human health and pathology
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10. Full Text Interaction between IGF2‐PI3K axis and cancer‐associated‐fibroblasts promotes anal squamous carcinogenesis
by Cacheux, Wulfran and Lièvre, Astrid and Richon, Sophie and Vacher, Sophie and El Alam, Elsy and Briaux, Adrien and El Botty, Rania and Mariani, Pascale and Buecher, Bruno and Schnitzler, Anne and Barbazan, Jorge and Roman‐Roman, Sergio and Bièche, Ivan and Dangles‐Marie, Virginie
International Journal of Cancer, ISSN 0020-7136, 10/2019, Volume 145, Issue 7, pp. 1852 - 1859
Anal squamous cell carcinoma (ASCC) is a rare tumour, but its incidence is increasing. Standard chemoradiotherapy fails to cure 20% of patients and no targeted... 
cancer‐associated fibroblast | PDGFRB | IGF2 | PI3K | anal cancer | cancer-associated fibroblast | HEAD | ONCOLOGY | BIOLOGY | TUMOR | CELL CARCINOMA | PROGRESSION | HIV (Viruses) | Carcinogenesis | Squamous cell carcinoma | TOR protein | Secretion | Paracrine signalling | AKT protein | Gene expression | 1-Phosphatidylinositol 3-kinase | Signal transduction | Carcinogens | Fibroblasts | Tumorigenesis | Insulin-like growth factor II | PTEN protein | Cancer | Tumors | Index Medicus
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11. Full Text Prognostic value of serum CYFRA 21-1 1 in patients with anal canal squamous cell carcinoma treated with radio(chemo)therapy
by Gauthé, Mathieu and Richard-Molard, Marion and Rigault, Eugénie and Buecher, Bruno and Mariani, Pascale and Bellet, Dominique and Cacheux, Wulfran and Lièvre, Astrid
BMC Cancer, ISSN 1471-2407, 04/2018, Volume 18, Issue 1, pp. 417 - 8
Background: We aimed to assess the prognostic value of CYFRA 21-1 in a series of patients with anal canal squamous cell carcinoma treated by radiation-based... 
Recurrence | Prognosis | CYFRA 21-1 | Tumour marker | Anal carcinoma | ABDOMINOPERINEAL RESECTION | DIAGNOSIS | TUMOR-MARKERS | FOLLOW-UP | CANCER | SCC | ONCOLOGY | CEA | ANTIGEN | Carcinoma, Squamous Cell - blood | Follow-Up Studies | Humans | Middle Aged | Male | Biomarkers, Tumor | Carcinoma, Squamous Cell - mortality | Antigens, Neoplasm - blood | Keratin-19 - blood | Aged, 80 and over | Anus Neoplasms - therapy | Adult | Female | Chemoradiotherapy - methods | Kaplan-Meier Estimate | Neoplasm Recurrence, Local | Proportional Hazards Models | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Anus Neoplasms - pathology | Anus Neoplasms - blood | Anus Neoplasms - mortality | ROC Curve | Aged | Neoplasm Staging | Life Sciences | Chemical Sciences | Cancer
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12. Full Text Docetaxel, cisplatin, and fluorouracil chemotherapy for metastatic or unresectable locally recurrent anal squamous cell carcinoma (Epitopes-HPV02): a multicentre, single-arm, phase 2 study
by Kim, Stefano and François, Eric and André, Thierry and Samalin, Emmanuelle and Jary, Marine and El Hajbi, Farid and Baba-Hamed, Nabil and Pernot, Simon and Kaminsky, Marie-Christine and Bouché, Olivier and Desrame, Jérôme and Zoubir, Mustapha and Ghiringhelli, François and Parzy, Aurélie and De La Fouchardiere, Christelle and Smith, Denis and Deberne, Mélanie and Spehner, Laurie and Badet, Nicolas and Adotevi, Olivier and Anota, Amélie and Meurisse, Aurélia and Vernerey, Dewi and Taieb, Julien and Vendrely, Véronique and Buecher, Bruno and Borg, Christophe
The Lancet Oncology, ISSN 1470-2045, 08/2018, Volume 19, Issue 8, pp. 1094 - 1106
The incidence of anal squamous cell carcinoma has been increasing markedly in the past few decades. Currently, there is no validated treatment for... 
TRIAL | 5-FLUOROURACIL | CARBOPLATIN | HUMAN-PAPILLOMAVIRUS TYPE-16 | ONCOLOGY | GASTRIC-CANCER | FLUOROPYRIMIDINE | BLEOMYCIN | MITOMYCIN | COMBINATION | PACLITAXEL | Humans | Middle Aged | Neoplasm Recurrence, Local - drug therapy | Male | Cisplatin - administration & dosage | Docetaxel - administration & dosage | Carcinoma, Squamous Cell - drug therapy | Carcinoma, Squamous Cell - mortality | Fluorouracil - administration & dosage | Neoplasm Metastasis - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Anus Neoplasms - drug therapy | Progression-Free Survival | Anus Neoplasms - mortality | Carcinoma, Squamous Cell - secondary | Female | Aged | Squamous cell carcinoma | Chemotherapy | Analysis | Docetaxel | Metastasis | Antigenic determinants | Cancer | Life Sciences
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13. Full Text Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations
by Rebbeck, Timothy R and Friebel, Tara M and Friedman, Eitan and Hamann, Ute and Huo, Dezheng and Kwong, Ava and Olah, Edith and Olopade, Olufunmilayo I and Solano, Angela R and Teo, Soo‐Hwang and Thomassen, Mads and Weitzel, Jeffrey N and Chan, TL and Couch, Fergus J and Goldgar, David E and Kruse, Torben A and Palmero, Edenir Inêz and Park, Sue Kyung and Torres, Diana and Rensburg, Elizabeth J and McGuffog, Lesley and Parsons, Michael T and Leslie, Goska and Aalfs, Cora M and Abugattas, Julio and Adlard, Julian and Agata, Simona and Aittomäki, Kristiina and Andrews, Lesley and Andrulis, Irene L and Arason, Adalgeir and Arnold, Norbert and Arun, Banu K and Asseryanis, Ella and Auerbach, Leo and Azzollini, Jacopo and Balmaña, Judith and Barile, Monica and Barkardottir, Rosa B and Barrowdale, Daniel and Benitez, Javier and Berger, Andreas and Berger, Raanan and Blanco, Amie M and Blazer, Kathleen R and Blok, Marinus J and Bonadona, Valérie and Bonanni, Bernardo and Bradbury, Angela R and Brewer, Carole and Buecher, Bruno and Buys, Saundra S and Caldes, Trinidad and Caliebe, Almuth and Caligo, Maria A and Campbell, Ian and Caputo, Sandrine M and Chiquette, Jocelyne and Chung, Wendy K and Claes, Kathleen B.M and Collée, J. Margriet and Cook, Jackie and Davidson, Rosemarie and la Hoya, Miguel and Leeneer, Kim and Pauw, Antoine and Delnatte, Capucine and Diez, Orland and Ding, Yuan Chun and Ditsch, Nina and Domchek, Susan M and Dorfling, Cecilia M and Velazquez, Carolina and Dworniczak, Bernd and Eason, Jacqueline and Easton, Douglas F and Eeles, Ros and Ehrencrona, Hans and Ejlertsen, Bent and Engel, Christoph and Engert, Stefanie and Evans, D. Gareth and Faivre, Laurence and Feliubadaló, Lidia and Ferrer, Sandra Fert and Foretova, Lenka and Fowler, Jeffrey and Frost, Debra and Galvão, Henrique C. R and Ganz, Patricia A and Garber, Judy and Gauthier‐Villars, Marion and Gehrig, Andrea and Gerdes, Anne‐Marie and Gesta, Paul and Giannini, Giuseppe and Giraud, Sophie and Glendon, Gord and Godwin, Andrew K and Greene, Mark H and ... and KConFab Investigators and HEBON and EMBRACE and GEMO Study Collaborators
Human Mutation, ISSN 1059-7794, 05/2018, Volume 39, Issue 5, pp. 593 - 620
The prevalence and spectrum of germline mutations in BRCA1 and BRCA2 have been reported in single populations, with the majority of reports focused on White in... 
mutation | ethnicity | ovarian cancer | geography | breast cancer | BRCA1 | BRCA2 | GENE-MUTATIONS | HEREDITARY BREAST | 185DELAG MUTATION | FOUNDER MUTATIONS | RECURRENT BRCA1 | HAPLOTYPE ANALYSIS | PHENOTYPE ANALYSIS | HIGH-RISK | GENETICS & HEREDITY | BREAST-CANCER PATIENTS | GERMLINE MUTATIONS | Genetic aspects | BRCA mutations | Genetic screening | Singers | Ovarian cancer | BRCA2 protein | Mutation | Genotyping | BRCA1 protein | Minority & ethnic groups | Geography | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Breast cancer | Medicinsk genetik | Medical Genetics | Ethnicity | Medicinska och farmaceutiska grundvetenskaper
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