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by Sturm, Dominik and Orr, Brent A and Toprak, Umut H and Hovestadt, Volker and Jones, David T.W and Jones, Chris and Capper, David and Sill, Martin and Buchhalter, Ivo and Northcott, Paul A and Leis, Irina and Ryzhova, Marina and Koelsche, Christian and Pfaff, Elke and Allen, Sariah J and Balasubramanian, Gnanaprakash and Worst, Barbara C and Pajtler, Kristian W and Brabetz, Sebastian and Johann, Pascal D and Sahm, Felix and Reimand, Jüri and Mackay, Alan and Carvalho, Diana M and Remke, Marc and Phillips, Joanna J and Perry, Arie and Cowdrey, Cynthia and Drissi, Rachid and Fouladi, Maryam and Giangaspero, Felice and Łastowska, Maria and Grajkowska, Wiesława and Scheurlen, Wolfram and Pietsch, Torsten and Hagel, Christian and Gojo, Johannes and Lötsch, Daniela and Berger, Walter and Slavc, Irene and Haberler, Christine and Jouvet, Anne and Holm, Stefan and Hofer, Silvia and Prinz, Marco and Keohane, Catherine and Fried, Iris and Mawrin, Christian and Scheie, David and Mobley, Bret C and Schniederjan, Matthew J and Santi, Mariarita and Buccoliero, Anna M and Dahiya, Sonika and Kramm, Christof M and von Bueren, André O and von Hoff, Katja and Rutkowski, Stefan and Herold-Mende, Christel and Frühwald, Michael C and Milde, Till and Hasselblatt, Martin and Wesseling, Pieter and Rößler, Jochen and Schüller, Ulrich and Ebinger, Martin and Schittenhelm, Jens and Frank, Stephan and Grobholz, Rainer and Vajtai, Istvan and Hans, Volkmar and Schneppenheim, Reinhard and Zitterbart, Karel and Collins, V. Peter and Aronica, Eleonora and Varlet, Pascale and Puget, Stephanie and Dufour, Christelle and Grill, Jacques and Figarella-Branger, Dominique and Wolter, Marietta and Schuhmann, Martin U and Shalaby, Tarek and Grotzer, Michael and van Meter, Timothy and Monoranu, Camelia-Maria and Felsberg, Jörg and Reifenberger, Guido and Snuderl, Matija and Forrester, Lynn Ann and Koster, Jan and Versteeg, Rogier and Volckmann, Richard and van Sluis, Peter and Wolf, Stephan and Mikkelsen, Tom and Gajjar, Amar and Aldape, Kenneth and Moore, Andrew S and Taylor, Michael D and ...
Cell, ISSN 0092-8674, 02/2016, Volume 164, Issue 5, pp. 1060 - 1072
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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 44, pp. 17921 - 17926
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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2009, Volume 106, Issue 9, pp. 3065 - 3070
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Cancer Cell, ISSN 1535-6108, 10/2017, Volume 32, Issue 4, pp. 520 - 537.e5
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Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8214 - 13
Genome editing is the introduction of directed modifications in the genome, a process boosted to therapeutic levels by designer nucleases. Building on the... 
Protein kinase C | Severe combined immunodeficiency | Transplants & implants | CD8 antigen | Immune reconstitution | Genomes | Lymphocytes T | Transplantation | Kinases | Progenitor cells | Blood | Hemopoiesis | Thymus | CD4 antigen | DNA-dependent protein kinase | Fibroblasts | Zinc finger proteins | Gene therapy | Deoxyribonucleic acid--DNA
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Haematologica, ISSN 0390-6078, 2016, Volume 101, Issue 5, pp. 616 - 625
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by Jones, David T. W and Jäger, Natalie and Kool, Marcel and Zichner, Thomas and Hutter, Barbara and Sultan, Marc and Cho, Yoon-Jae and Pugh, Trevor J and Hovestadt, Volker and Stütz, Aian M and Rausch, Tobias and Warnatz, Hans-Jörg and Ryzhova, Marina and Bender, Sebastian and Sturm, Dominik and Pleier, Sabrina and Cin, Huriye and Pfaff, Elke and Sieber, Laura and Wittmann, Anea and Remke, Marc and Witt, Henik and Hutter, Sonja and Tzaridis, Theophilos and Weischenfeldt, Joachim and Raeder, Benjamin and Avci, Meryem and Amstislavskiy, Vyacheslav and Zapatka, Marc and Weber, Ursula D and Wang, Qi and Lasitschka, Bärbel and Bartholomae, Cynthia C and Schmidt, Manfred and von Kalle, Christof and Ast, Volker and Lawerenz, Chris and Eils, Jürgen and Kabbe, Rolf and Benes, Vladimir and van Sluis, Peter and Koster, Jan and Volckmann, Richard and Shih, David and Betts, Matthew J and Russell, Robert B and Coco, Simona and Tonini, Gian Paolo and Schüller, Ulrich and Hans, Volkmar and Graf, Norbert and Kim, Yoo-Jin and Monoranu, Camelia and Roggendorf, Wolfgang and Unterberg, Aneas and Herold-Mende, Christel and Milde, Till and Kulozik, Aneas E and von Deimling, Aneas and Witt, Olaf and Maass, Eberhard and Rössler, Jochen and Ebinger, Martin and Schuhmann, Martin U and Frühwald, Michael C and Hasselblatt, Martin and Jabado, Nada and Rutkowski, Stefan and von Bueren, Ané O and Williamson, Dan and Clifford, Steven C and McCabe, Martin G and Collins, V. Peter and Wolf, Stephan and Wiemann, Stefan and Lehrach, Hans and Brors, Benedikt and Scheurlen, Wolfram and Felsberg, Jörg and Reifenberger, Guido and Northcott, Paul A and Taylor, Michael D and Meyerson, Matthew and Pomeroy, Scott L and Yaspo, Marie-Laure and Korbel, Jan O and Korshunov, Aney and Eils, Roland and Pfister, Stefan M and Lichter, Peter
Nature, ISSN 0028-0836, 2012, Volume 488, Issue 7409, pp. 100 - 105
Medulloblastoma is an aggressively growing tumour, arising in the cerebellum or medulla/brain stem. It is the most common malignant brain tumour in children,... 
ACTIVATION | PATHWAY | LANDSCAPE | MULTIDISCIPLINARY SCIENCES | GENES | TETRAPLOID TUMOR-CELLS | TBR1 | MUTATIONS | SUBGROUPS | CANCER | Chromatin - metabolism | Cerebellar Neoplasms - diagnosis | Genomics | Humans | Hedgehog Proteins - metabolism | Wnt Proteins - metabolism | Histone Demethylases - genetics | Aging - genetics | Medulloblastoma - pathology | Cerebellar Neoplasms - pathology | Patched Receptors | Cerebellar Neoplasms - classification | Medulloblastoma - genetics | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Child | DNA Helicases - genetics | Amino Acid Sequence | Polyploidy | Signal Transduction | Chromosomes, Human - genetics | Medulloblastoma - diagnosis | Mutation Rate | Cerebellar Neoplasms - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | T-Box Domain Proteins - genetics | Genome, Human - genetics | beta Catenin - genetics | DEAD-box RNA Helicases - genetics | Phosphoprotein Phosphatases - genetics | Sequence Analysis, RNA | Cell Transformation, Neoplastic | Oncogene Proteins, Fusion - genetics | High-Throughput Nucleotide Sequencing | Methylation | Medulloblastoma - classification | Patched-1 Receptor | Receptors, Cell Surface - genetics | Medulloblastoma | Physiological aspects | Development and progression | Genetic aspects | Research | Metastasis | Cancer
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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2019, Volume 116, Issue 19, pp. 9318 - 9323
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Journal of Clinical Oncology, ISSN 0732-183X, 08/2013, Volume 31, Issue 23, pp. 2927 - 2935
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by Veldhuijzen van Zanten, Sophie E. M and Baugh, Joshua and Chaney, Brooklyn and de Jongh, Dennis and Sanchez Aliaga, Esther and Barkhof, Frederik and Noltes, Johan and de Wolf, Ruben and van Dijk, Jet and Cannarozzo, Antonio and Damen-Korbijn, Carin M and Lieverst, Jan A and Colditz, Niclas and Hoffmann, Marion and Warmuth-Metz, Monika and Bison, Brigitte and Jones, David T. W and Sturm, Dominik and Gielen, Gerrit H and Jones, Chris and Hulleman, Esther and Calmon, Raphael and Castel, David and Varlet, Pascale and Giraud, Géraldine and Slavc, Irene and van Gool, Stefaan and Jacobs, Sana and Jaijevic-Cvrlje, Filip and Sumerauer, David and Nysom, Karsten and Pentikainen, Virve and Kivivuori, Sanna-Maria and Leblond, Pierre and Entz-Werle, Natasha and von Bueren, Ane O and Kattamis, Antonis and Hargrave, Darren R and Hauser, Péter and Garami, Miklos and Thorarinsdottir, Halldora K and Pears, Jane and Gandola, Lorenza and Rutkauskiene, Giee and Janssens, Geert O and Torsvik, Ingrid K and Perek-Polnik, Marta and Gil-da-Costa, Maria J and Zheludkova, Olga and Shats, Liudmila and Deak, Ladislav and Kitanovski, Lidija and Cruz, Ofelia and Morales La Maid, Anes and Holm, Stefan and Gerber, Nicolas and Kebudi, Rejin and Grundy, Richard and Lopez-Aguilar, Enrique and Zapata-Tarres, Marta and Emmerik, John and Hayden, Tim and Bailey, Simon and Biassoni, Veronica and Massimino, Maura and Grill, Jacques and Vandertop, William P and Kaspers, Gertjan J. L and Fouladi, Maryam and Kramm, Christof M and van Vuurden, Dannis G and SIOPE DIPG Network and members of the SIOPE DIPG Network and on behalf of the members of the SIOPE DIPG Network
Journal of neuro-oncology, ISSN 0167-594X, 2017, Volume 132, Issue 2, pp. 255 - 266
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