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Bulletin of Experimental Biology and Medicine, ISSN 0007-4888, 2/2019, Volume 166, Issue 4, pp. 456 - 460
We performed an in vivo comparative study of activity of three substances of the nitrosourea group produced in Russia. All substances demonstrated high... 
Biomedicine, general | Pathology | Biomedicine | antitumor activity | tumor | Internal Medicine | nitrosourea-based substances | Laboratory Medicine | Cell Biology | MEDICINE, RESEARCH & EXPERIMENTAL | Mice | Lung cancer | Analysis | Cervical cancer | Tumors
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 2/2018, Volume 51, Issue 11, pp. 1021 - 1024
The possible interchangeability of eye drops was analyzed using glaucoma medicines containing latanoprost as examples. It was shown that the reference and... 
interchangeability | eye drops | generic drugs | latanoprost | Pharmacy | glaucoma | Pharmacology/Toxicology | excipients | Organic Chemistry | XALATAN(R) | CHEMISTRY, MEDICINAL | OCULAR HYPERTENSION | PHARMACOLOGY & PHARMACY | GENERIC LATANOPROST | Glaucoma | Generic drugs | Usage | Ophthalmic drugs | Analysis | Drug therapy | Health aspects
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 11/2017, Volume 51, Issue 8, pp. 695 - 697
Medicinal effects on gastrointestinal-tract (GIT) organs under normal and pathological conditions are reviewed and analyzed. It is shown that rhythmic... 
chronopathology | digestive system | chronorhythm | Pharmacy | Pharmacology/Toxicology | circadian rhythms | Organic Chemistry | desynchronosis | CHEMISTRY, MEDICINAL | PHARMACOLOGY & PHARMACY | Medical colleges
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 10/2018, Volume 52, Issue 7, pp. 611 - 614
The potentially immunoactive lysine-containing tetrapeptide H-Lys-Ala-Val-Gly-OH was synthesized. The value of using a method based on mixed anhydrides and... 
lysine | peptide bioregulators | Pharmacy | acute toxicity | amino acids | Pharmacology/Toxicology | immunoactivity | peptide synthesis | Organic Chemistry | CHEMISTRY, MEDICINAL | PHARMACOLOGY & PHARMACY
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 3/2017, Volume 50, Issue 12, pp. 814 - 816
The principles for assessing therapeutic equivalence based on bioequivalence studies as accepted in Russia are significantly different from those adopted... 
narrow therapeutic index drugs | generic drugs | Pharmacy | narrow therapeutic index | Pharmacology/Toxicology | bioequivalence | Organic Chemistry | PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | Drugs | Health aspects
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 12/2016, Volume 50, Issue 9, pp. 620 - 624
The coordination complex of the dipeptide isoleucyl-tryptophan with Fe(II) possesses immunostimulating activity and is effective for treating iron- and... 
method validation | timofer [isoleucyl-tryptophan dipeptide complex with iron(II)] | foreign impurities | assay | Pharmacy | identity | Pharmacology/Toxicology | analytical methods | Organic Chemistry | CHEMISTRY, MEDICINAL | PHARMACOLOGY & PHARMACY | Medical colleges | Peptides | Quality control | Tryptophan | Backup software | Methods | Quality management
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 2/2018, Volume 51, Issue 11, pp. 1037 - 1040
Validation results for a spectrophotometric quantitative determination method for ormustine in a lyophilized dosage form are presented. The method is shown to... 
spectrophotometry | Pharmacology/Toxicology | Pharmacy | validation | Organic Chemistry | ormustine | PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 6/2016, Volume 50, Issue 3, pp. 181 - 184
The presence of several generics on the pharmaceutical market makes it possible to create a competitive environment and helps to reduce the costs of drug... 
interchangeability | antiepileptic drugs | generic drugs | Pharmacy | Pharmacology/Toxicology | bioequivalence | Organic Chemistry | CHEMISTRY, MEDICINAL | PERSPECTIVE | PHARMACOLOGY & PHARMACY | IDENTIFICATION | GENERIC PRODUCTS | Generic drugs | Anticonvulsants | Health aspects | Patient compliance | Quality control | Quality management
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 7/2017, Volume 51, Issue 4, pp. 307 - 311
Lyophilization (freeze drying) is among the most effective methods used to stabilize drugs and increase their shelf life. It is influenced by many factors, the... 
freeze drying | drying regime | liposomes | Pharmacy | lyophilizate structure | Pharmacology/Toxicology | excipients | Organic Chemistry | CHEMISTRY, MEDICINAL | PHARMACOLOGY & PHARMACY | FORMULATION | Medical colleges | Analysis | Methods
Journal Article
Chemistry of Heterocyclic Compounds, ISSN 0009-3122, 5/2019, Volume 55, Issue 4, pp. 386 - 391
A suitable approach to the synthesis of 7-arylimidazo[1,2-a]pyrazin-8(7H)-ones starting from esters of oxalic acid monoamides via cyclization of intermediate... 
imidazo[1,2- a ]pyrazin-8(7 H )-one | Chemistry | Pharmacy | 3-aminopyrazin-2(1 H )-one | 2-halophenylethanone | 3-methoxypyrazin-2(1 H )-one | pyrazine-2,3-dione | cyclization | Organic Chemistry | 3-aminopyrazin-2(1H)-one | imidazo | POTENT | 2-a]pyrazin-8(7H)-one | pyrazine-2 | CHEMISTRY, ORGANIC | 3-methoxypyrazin-2(1H)-one | 3-dione | Oxalic acid | Oxalates
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 12/2016, Volume 50, Issue 9, pp. 625 - 629
Amethod for determining anticomplementary activity of human immunoglobulin (Ig) preparations for i.v. administration by complement fixation test was validated... 
method validation | Pharmacy | human immunoglobulins | Pharmacology/Toxicology | anticomplementary activity | Organic Chemistry | specific safety | PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 1/2017, Volume 50, Issue 10, pp. 684 - 690
The present research was aimed at finding informative criteria for regulating the procedure to determine the interchangeability of systemic levofloxacin-based... 
generic drug | levofloxacin | Pharmacy | interchangeable products | Pharmacology/Toxicology | excipients | Organic Chemistry | Levofloxacin | Excipients | Generic drug | Interchangeable products | INTESTINAL-ABSORPTION | CHEMISTRY, MEDICINAL | PHARMACOLOGY & PHARMACY
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 8/2017, Volume 51, Issue 5, pp. 399 - 401
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 10/2015, Volume 49, Issue 7, pp. 473 - 476
Anti-complement activity is a measure of the specific safety of human immunoglobulins characterizing one of the unwanted effect - spontaneous activation of the... 
anti-complement activity | standard immunoglobulin | human immunoglobulin | Pharmacy | Pharmacology/Toxicology | Organic Chemistry | specific safety | PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL
Journal Article
AIP Conference Proceedings, ISSN 0094-243X, 12/2009, Volume 1182, Issue 1
Jet production in electron-proton scattering at HERA provides an important testing ground for Quantum Chromodynamics and allows improved determinations of the... 
ELECTRON-PROTON INTERACTIONS | PHYSICS OF ELEMENTARY PARTICLES AND FIELDS | JET MODEL | NEUTRAL CURRENTS | PHOTOPRODUCTION | CROSS SECTIONS | QUANTUM CHROMODYNAMICS | MULTIPLE PRODUCTION | STRONG-COUPLING MODEL | COUPLING CONSTANTS | DEEP INELASTIC SCATTERING | HADRONS | HERA STORAGE RING
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 3/2017, Volume 50, Issue 12, pp. 833 - 836
An evaluation and stability study of the original Russian human immunoglobulin standard intended for determining the anticomplementary activity and assessing... 
Pharmacy | human immunoglobulins | Pharmacology/Toxicology | anticomplementary activity | Organic Chemistry | standard sample | certification | PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | Immunoglobulins | Analysis | Standards | Quality control
Journal Article
Pharmaceutical Chemistry Journal, ISSN 0091-150X, 12/2014, Volume 48, Issue 9, pp. 632 - 634
We describe here the development of the immunomodulatory agent timofer, which is a 0.0148% aqueous solution of coordination compounds of the dipeptide... 
coordination compounds | Pharmacy | immunomodulator drug | peptides | Pharmacology/Toxicology | Organic Chemistry | timofer | PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | Peptides | Tryptophan | Sulfates
Journal Article
Proceedings of the 10th International Conference, ISSN 0094-243X, 05/2009, Volume 1182, pp. 479 - 482
Jet production in electron-proton scattering at HE' A provides an important testing ground for Quantum Chromodynamics and allows improved determinations of the... 
Journal Article
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