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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 137, Issue 2, pp. 517 - 526.e3
Background Severe combined immunodeficiency (SCID) represents congenital disorders characterized by a deficiency of T cells caused by arrested development in... 
Allergy and Immunology | B-cell development | thymus | NSG | adenosine deaminase | Artemis | IL7RA | IL2RG | T-cell development | SCID | RECOMBINATION | PROGENITORS | LYMPHOID DEVELOPMENT | IMMUNOGLOBULIN | DEFICIENT MICE | IMMUNOLOGY | REARRANGEMENTS | GAMMA-CHAIN | ALLERGY | DIFFERENTIATION | EXPRESSION | Humans | Stem Cells - cytology | Stem Cells - metabolism | Cell Differentiation - genetics | Heterografts | T-Lymphocytes - metabolism | Antigens, Surface - metabolism | Female | B-Lymphocytes - metabolism | B-Lymphocytes - cytology | Receptors, Antigen, T-Cell - metabolism | Lymphoid Progenitor Cells - metabolism | Hematopoietic Stem Cell Transplantation | Immunophenotyping | Mice, Transgenic | Lymphoid Progenitor Cells - cytology | Severe Combined Immunodeficiency - etiology | Cell Differentiation - immunology | Phenotype | Animals | T-Lymphocytes - cytology | Gene Rearrangement | Hematopoietic Stem Cells - cytology | Mice, Inbred NOD | Mice | Receptors, Antigen, T-Cell - genetics | Thymus Gland - embryology | Mutation | Immunoglobulin Heavy Chains - genetics | Severe combined immunodeficiency | T cells | Stem cells | Analysis | Bone marrow | Transplantation | Gene expression | Pediatrics | Flow cytometry | Research & development--R&D | T cell receptors | Kinases | Human subjects | Lymphocytes | Phenols | Growth factors | Deoxyribonucleic acid--DNA
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 1/2012, Volume 69, Issue 1, pp. 59 - 73
Primary antibody deficiencies (PAD) form the largest group of inherited disorders of the immune system. They are characterized by a marked reduction or absence... 
Life Sciences | Biochemistry, general | Serum immunoglobulin | Life Sciences, general | Primary antibody deficiency | Agammaglobulinemia | Immunoglobulin class switch recombination deficiency | Idiopathic hypogammaglobulinemia | Biomedicine general | Cell Biology | B-CELL DEVELOPMENT | CLASS SWITCH RECOMBINATION | SOMATIC HYPERMUTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | X-LINKED AGAMMAGLOBULINEMIA | COMMON VARIABLE IMMUNODEFICIENCY | ICOS DEFICIENCY | CELL BIOLOGY | BRUTONS TYROSINE KINASE | TRANSMEMBRANE ACTIVATOR | GENE-THERAPY | AUTOSOMAL RECESSIVE FORM | Common Variable Immunodeficiency - immunology | Agammaglobulinemia - immunology | B-Lymphocytes - cytology | Agammaglobulinemia - genetics | Immunoglobulins - immunology | Humans | Immunoglobulin Class Switching - immunology | Agammaglobulinemia - diagnosis | Common Variable Immunodeficiency - genetics | Immunoglobulins - genetics | Immunoglobulins - deficiency | Mice, Knockout | Common Variable Immunodeficiency - diagnosis | Cell Differentiation - genetics | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | Animals | B-Lymphocytes - immunology | Immunologic Deficiency Syndromes - genetics | Mice | Immunologic Deficiency Syndromes - diagnosis | Immunologic Deficiency Syndromes - immunology | Immunoglobulin Class Switching - genetics | Immunoglobulins | Genetic disorders | Genes | Vaccination | Vaccines | Medical disorders | Immune system | Recombination | Reviews | agammaglobulinemia | Lymphocytes B | Hypogammaglobulinemia | Differentiation | Class switching | Hereditary diseases
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 12/2017, Volume 8, Issue DEC, p. 1859
textabstractRespiratory support improvements have aided survival of premature neonates, but infection susceptibility remains a predominant problem. We... 
Diversity analysis | Public clonotypes | T-cell receptor repertoire | Convergent recombination | Neonate | Preterm | HEAVY-CHAIN GENES | diversity analysis | public clonotypes | preterm | neonate | IMMUNOLOGY | RESPONSES | HUMAN FETAL LIVER | convergent recombination | N-REGIONS | INFANTS | MICE | DIVERSITY | INFLUENZA-VIRUS | EXPRESSION | CDR3
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 12/2011, Volume 2, Issue MAY
textabstractThe vast majority of patients suffering from a primary immunodeficiency (PID) have defects in their T- and/or B-cell compartments. Despite advances... 
Argammaglobulinemia | Primary immunodeficiencies | T-cell | B-cell | Krec | V(D)J recombination | Trec | Scid | argammaglobulinemia | primary immunodeficiencies | KREC | TREC | IMMUNOLOGY | SCID | B cell | Agammaglobulinemia | T cell | V(D)J Recombination
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2013, Volume 72, Issue 6, pp. 1037 - 1043
Journal Article
Journal Article
Journal of Clinical Immunology, ISSN 0271-9142, 02/2017, Volume 37, Issue 2, pp. 133 - 142
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 06/2019, Volume 105, Issue 6, pp. 1456 - 1461
Regorafenib exposure could potentially be influenced by an interaction with acid‐reducing drugs. In this crossover trial, patients were randomized into two... 
MULTICENTER | EFFICACY | TYROSINE-KINASE INHIBITORS | FOCUS | PHARMACOLOGY & PHARMACY | SORAFENIB | CANCER | DRUG-DRUG INTERACTIONS | Research
Journal Article