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1. Full Text Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial
by Baharoglu, M Irem, MD and Cordonnier, Charlotte, Prof and Salman, Rustam Al-Shahi, Prof and de Gans, Koen, MD and Koopman, Maria M, PhD and Brand, Anneke, Prof and Majoie, Charles B, Prof and Beenen, Ludo F, PhD and Marquering, Henk A, PhD and Vermeulen, Marinus, Prof and Nederkoorn, Paul J, PhD and de Haan, Rob J, Prof and Roos, Yvo B, Prof and PATCH Investigators
Lancet, The, ISSN 0140-6736, 2016, Volume 387, Issue 10038, pp. 2605 - 2613
Summary Background Platelet transfusion after acute spontaneous primary intracerebral haemorrhage in people taking antiplatelet therapy might reduce death or... 
Internal Medicine | MORTALITY | MEDICINE, GENERAL & INTERNAL | OXFORDSHIRE | COMMUNITY | DISEASE | GROWTH | INTRACEREBRAL HEMORRHAGE | SUBARACHNOID HEMORRHAGE | AGENTS | INTRACRANIAL HEMORRHAGE | Cerebral Hemorrhage - chemically induced | Length of Stay | Platelet Transfusion | Europe | Humans | Middle Aged | Cerebral Hemorrhage - mortality | Male | Treatment Outcome | Stroke - chemically induced | Aged, 80 and over | Adult | Cerebral Hemorrhage - therapy | Female | Aged | Stroke - mortality | Stroke - therapy | Platelet Aggregation Inhibitors - adverse effects | Stroke (Disease) | Clinical trials | Transfusion | Blood platelets | Biomedical engineering | Medical care | Quality management | Blood transfusions | Brain | Adenosine | Stroke | Brain research | Embolisms | Drug therapy | Hemorrhage | Coma | Heart | Neuroimaging | Therapy | Ethics | Randomization | Motivation | Dependence | Population | Medical imaging | Research & development--R&D | Mortality | Regression analysis | Hospitals | Fatalities | Death | Diagnostic systems | Platelets
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2. Full Text Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial
by Al-Shahi Salman, Rustam and Minks, David P and Minks, David and Mitra, Dipayan and Rodrigues, Mark A and Bhatnagar, Priya and du Plessis, Johannes and du Plessis, Johann C and Joshi, Yogish and Dennis, Martin S and Dennis, Martin and Murray, Gordon D and Newby, David E and Sandercock, Peter A G and Sprigg, Nikola and Stephen, Jacqueline and Sudlow, Cathie and Sudlow, Cathie L M and Werring, David and Werring, David J and Whiteley, William N and Whiteley, William and Wardlaw, Joanna M and White, Julie and White, Philip M and White, James and White, Susan and Baigent, Colin and Lasserson, Daniel and Sullivan, Frank and Carrie, Johanna and Rojas, Javier and Amoils, Shannon and Bamford, John and Armitage, Jane and Rinkel, Gabriel and Lowe, Gordon and Emberson, Jonathan and Innes, Karen and Dinsmore, Lynn and Drever, Jonathan and Williams, Rebecca and Williams, Carol and Perry, David and Perry, Jack and McGill, Connor and Buchanan, David and Walker, Susannah and Walker, Marion and Walker, Pauli and Walker, Allan and Hutchison, Aidan and Matthews, Christopher and Fraser, Ruth and McGrath, Aileen and Deary, Ann and Anderson, Rosemary and Hansen, Christian and Parker, Richard and Rodriguez, Aryelly and Macleod, Malcolm and Gattringer, Thomas and Palmer, Jeb and Sakka, Eleni and Adil-Smith, Jennifer and Lerpiniere, Christine and O'Brien, Eoin and O'Brien, Richard and Burgess, Seona and Burgess, Laura and Mead, Denise and Mead, Gillian and Paulton, Ruth and Doubal, Fergus and McCormick, Katrina and Hunter, Neil and Hunter, Annemarie and Taylor, Vicky and Taylor, Pat and Parakramawansha, Ruwan and Blair, Caroline and Blair, Gordon and MacRaild, Allan and Parry-Jones, Adrian and Johnes, Mary and Lee, Stephanie and Shaw, Louise and Shaw, Kelly Marie and Burger, Ilse and Punter, Martin and Ingham, Andrea and Perez, Jane and Naing, Zin and Morell, Jordi and Marsden, Tracy and Hall, Andrea and Marshall, Sally and Harrison, Thomas and Harrison, Melanie and Harrison, Louise and ... and RESTART Collaboration
The Lancet Neurology, ISSN 1474-4422, 07/2019, Volume 18, Issue 7, pp. 643 - 652
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared... 
CT | MICROBLEEDS | SUPERFICIAL SIDEROSIS | SIGNS | AMYLOID ANGIOPATHY | ACUTE ISCHEMIC-STROKE | ANTITHROMBOTIC THERAPY | ASPIRIN | CLINICAL NEUROLOGY | Atrophy | Neuroimaging | Anticoagulants | Stroke | Aspirin | Statistical analysis | Medical imaging | Magnetic resonance imaging | Computed tomography | Biomarkers | Hemorrhage
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3. Full Text Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial
by Dennis, Martin and Mead, Gillian and Mead, Denise and Forbes, John and Graham, Julie and Graham, Susan and Graham, Libby and Graham, Catriona and Hackett, Maree and Hankey, Graeme J and House, Allan and Lewis, Stephanie and Lundström, Erik and Sandercock, Peter and Innes, Karen and Williams, Carol and Williams, Sandra and Williams, Rhys and Williams, Richard and Williams, Rebecca and Williams, Max and Williams, Sarah and Drever, Jonathan and Mcgrath, Aileen and Deary, Ann and Fraser, Greig and Fraser, Ruth and Anderson, Rosemary and Walker, Rachel and Walker, Elaine and Walker, Pauli and Walker, Susannah and Perry, David and Perry, Jack and Mcgill, Connor and Buchanan, David and Chun, Yvonne and Dinsmore, Lynn and Maschauer, Emma and Barugh, Amanda and Mikhail, Shadia and Blair, Gordon and Hoeritzauer, Ingrid and Scott, Jon and Scott, Rhona and Scott, Maggie and Lawrence, Tara and Lawrence, Katherine and Shaw, Alison and Williamson, Sue and Williamson, Judith and Burgess, David and Burgess, Seona and Burgess, Laura and Macleod, Fiona and Macleod, Malcolm and Macleod, Mary Joan and Morales, Dan and Sullivan, Frank and Brady, Marian and French, Ray and Van Wijck, Frederike and Watkins, Caroline and Proudfoot, Fiona and Skwarski, Joanna and Mcgowan, Diane and Murphy, Peter and Murphy, Rachael and Rutherford, William and Mccormick, Katrina and Buchan, Ruaridh and Macraild, Allan and Paulton, Ruth and Fazal, Adnan and Taylor, Vicky and Taylor, Caroline and Taylor, Pat and Parakramawansha, Ruwan and Hunter, Neil and Hunter, Nadia and Bamford, Elizabeth and Bamford, John and Waugh, Darren and Waugh, Dean and Veraque, Emelda and Bedford, Caroline and Bedford, Elizabeth and Kambafwile, Mary and Idrovo, Luis and Makawa, Linetty and Smalley, Paula and Randall, Marc and Thirugnana-Chandran, Tharani and Hassan, Hanna and Hassan, Muhammad and Hassan, Ahamad and Vowden, Richard and Jackson, Samantha and Jackson, Tracy and Jackson, Linda and ... and FOCUS Trial Collaboration
The Lancet, ISSN 0140-6736, 01/2019, Volume 393, Issue 10168, pp. 265 - 274
Results of small trials indicate that fluoxetine might improve functional outcomes after stroke. The FOCUS trial aimed to provide a precise estimate of these... 
DEPRESSION | MEDICINE, GENERAL & INTERNAL | TELEPHONE | VALIDATION | VERSION | CLASSIFICATION | IMPACT SCALE | ISCHEMIC-STROKE | VALIDITY | Stroke | Fluoxetine | Medical services | Clinical trials | Recovery of function | Drug overdose | Mental depression | Patients | Optimization | Neurological diseases | Convulsions & seizures | Randomization | Fractures | Antidepressants | Technology assessment | Suicides & suicide attempts | Bone
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4. Full Text Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
by Al-Shahi Salman, Rustam and Dennis, MS and Sandercock, PAG and Sudlow, CLM and Wardlaw, JM and Whiteley, WN and Murray, GD and Stephen, J and Newby, DE and Sprigg, N and Werring, DJ and White, Susan and White, PM and White, Julie and White, James and Baigent, Colin and Lasserson, Daniel and Sullivan, Frank and Carrie, Johanna and Rojas, Javier and Amoils, Shannon and Bamford, John and Armitage, Jane and Rinkel, Gabriel and Lowe, Gordon and Emberson, Jonathan and Innes, Karen and Dinsmore, Lynn and Drever, Jonathan and Williams, Rebecca and Williams, Carol and Perry, Jack and Perry, David and McGill, Connor and Buchanan, David and Walker, Pauli and Walker, Marion and Walker, Allan and Walker, Susannah and Hutchison, Aidan and Matthews, Christopher and Fraser, Ruth and McGrath, Aileen and Deary, Ann and Anderson, Rosemary and Hansen, Christian and Parker, Richard and Rodriguez, Aryelly and Macleod, MR and Gattringer, Thomas and Palmer, Jeb and Sakka, Eleni and Adil-Smith, Jennifer and Minks, David and Mitra, Dipayan and Bhatnagar, Priya and du Plessis, Johannes and Joshi, Yogish and Lerpiniere, Christine and O'Brien, Richard and O'Brien, Eoin and Burgess, Laura and Burgess, Seona and Mead, Denise and Mead, Gillian and Paulton, Ruth and Doubal, Fergus and McCormick, Katrina and Hunter, Annemarie and Hunter, Neil and Taylor, Vicky and Taylor, Pat and Parakramawansha, Ruwan and Blair, Gordon and Blair, Caroline and MacRaild, Allan and Parry-Jones, Adrian and Johnes, Mary and Lee, Stephanie and Shaw, Kelly Marie and Shaw, Louise and Burger, Ilse and Punter, Martin and Ingham, Andrea and Perez, Jane and Naing, Zin and Morell, Jordi and Marsden, Tracy and Hall, Andrea and Marshall, Sally and Harrison, Melanie and Harrison, Thomas and Harrison, Louise and Jarapa, Rowilson and Wood, Edith and Wood, Lisa and Wood, Diane and O'Loughlin, Victoria and Cohen, David and Davies, Silvie and ... and RESTART Collaboration
The Lancet, ISSN 0140-6736, 06/2019, Volume 393, Issue 10191, pp. 2613 - 2623
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial... 
DEFINITIONS | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | MANAGEMENT | RESUMPTION | EVENTS | ANTITHROMBOTIC THERAPY | GUIDELINES | PREVENTION | ASPIRIN | INTRACRANIAL HEMORRHAGE | Anticoagulants | Therapy | Stroke | Heart attacks | Embolisms | Health risks | Risk | Systematic review | Hazards | Regression analysis | Patients | Hemorrhage | Thrombosis | Optimization | Disease prevention | Prevention | Randomization | Vascular diseases | Collaboration
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