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Journal of Experimental Biology, ISSN 0022-0949, 02/2015, Volume 218, Issue 4, pp. 506 - 514
The origin of neurons was a key event in evolution, allowing metazoans to evolve rapid behavioral responses to environmental cues. Reconstructing the origin of... 
Homer | Postsynaptic scaffold | Synapse evolution | Metazoans | Munc18 | SNARE | ACTIVATION | COMPLEXES | METABOTROPIC GLUTAMATE RECEPTORS | GENOME | FAMILY | BINDS | BIOLOGY | SHANK | CELL-DIFFERENTIATION | Biological Evolution | Nerve Tissue Proteins - physiology | Animals | Genome, Protozoan | Synapses - physiology | Choanoflagellata - genetics | Choanoflagellata - physiology | Neural transmission | Genomes | Research | Analysis | Metazoa
Journal Article
BioEssays, ISSN 0265-9247, 10/2017, Volume 39, Issue 10, pp. 1700024 - n/a
Journal Article
DEVELOPMENT, ISSN 0950-1991, 09/2019, Volume 146, Issue 18, p. dev178996
The EMBO/EMBL Symposium on 'The Identity and Evolution of Cell Types' took place in Heidelberg, Germany, on 15-19 May 2019. The symposium, which brought... 
Single cell sequencing | ORIGIN | Computational analysis | Cell fate | II COLLAGEN | TISSUE | GENE-EXPRESSION | Evolution | DEVELOPMENTAL BIOLOGY | REVEAL
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 38, pp. 13828 - 13833
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2014, Volume 111, Issue 38, p. 13828
  Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) and Sec1/Munc18 (SM) proteins constitute the core of an ancient vesicle fusion... 
Proteins | Eukaryotes | Peptides | Binding sites
Journal Article
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, ISSN 2296-634X, 10/2019, Volume 7
Choanoflagellates are the closest unicellular relatives of animals (Metazoa). These tiny protists display complex life histories that include sessile as well... 
multicellularity | cell differentiation | collar cells | DEVELOPMENTAL BIOLOGY | evolution | ANCESTRY | CELL BIOLOGY | sponge (Porifera) | ADHESION | ORIGIN | DIVERSITY | METAZOA | choanoflagellate | Medicine, Experimental | Medical research | Research | Cell differentiation | Metazoa
Journal Article
Current Opinion in Genetics & Development, ISSN 0959-437X, 2016, Volume 39, pp. 42 - 47
Choanoflagellates are the closest single-celled relatives of animals and provide fascinating insights into developmental processes in animals. Two species, the... 
Medical Education | PHYLOGENY | ORIGIN | NETWORK | EVOLUTION | GENETICS & HEREDITY | HOMER | METAZOAN | CELL-DIFFERENTIATION | PROTEINS | GENOME | INSIGHTS | CELL BIOLOGY | Animals | Choanoflagellata - growth & development | Models, Genetic | Choanoflagellata - genetics | Phylogeny | Genome | Evolution, Molecular | Evolution | Analysis | Cells
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 09/2011, Volume 108, Issue 37, pp. 15264 - 15269
SNARE protein-driven secretion of neurotransmitters from synaptic vesicles is at the center of neuronal communication. In the absence of the cytosolic protein... 
COMPLEX | ORIGIN | EVOLUTION | MUNC18-1 | MULTIDISCIPLINARY SCIENCES | CLOSED-CONFORMATION | N-PEPTIDE | VESICLE DOCKING | BINDING | GENOME | SNARE | Proteins | Physiological aspects | Neural transmission | Research | Neurosecretion | Flagellates | Biological Sciences
Journal Article
eLife, ISSN 2050-084X, 03/2016, Volume 5, Issue 2016
Activation triggers the exchange of subunits in Ca2+/calmodulin-dependent protein kinase II (CaMKII), an oligomeric enzyme that is critical for learning,... 
Enzymes | Phosphorylation | Peptides | Calcium | Memory | Kinases | Interfaces | Proteins | Learning | Calcium-binding protein | Heart diseases | Calmodulin | Ca2+/calmodulin-dependent protein kinase II
Journal Article