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PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2019, Volume 62, Issue 1, pp. 3 - 23
Excitatory activity in the CNS is predominately mediated by L-glutamate through several families of L-glutamate neurotransmitter receptors. Of these, the... 
GLUN2A-CONTAINING NMDARS | ACID-DERIVATIVES | POTENT | CHEMISTRY, MEDICINAL | STEROIDS | QUINAZOLIN-4-ONE DERIVATIVES | PREGNENOLONE-SULFATE | SYNAPTIC PLASTICITY | MOLECULAR-BASIS | NONCOMPETITIVE INHIBITION | SUBUNIT
Journal Article
Tetrahedron, ISSN 0040-4020, 11/2018, Volume 74, Issue 47, pp. 6737 - 6748
Oxidation of a 15-methylenebicyclo[9.3.1]pentadeca-3,7-dien-14-ol with a 10-phenylsulfonyl substituent provided a... 
Oxidation | Phomactins | Stereoselective reduction | Total synthesis | Tetra-n-propylammonium perruthenate | PHENYLSULFONES | CHEMISTRY, ORGANIC | REDUCTIVE LITHIATION | REARRANGEMENTS | CLEAVAGE | ANTAGONISTS | PRECURSORS | CYCLIZATION | Synthesis | Resveratrol | Organic compounds
Journal Article
Addiction (Abingdon, England), ISSN 0965-2140, 9/2017, Volume 112, Issue 9, pp. 1580 - 1589
Journal Article
Addiction, ISSN 0965-2140, 09/2017, Volume 112, Issue 9, pp. 1580 - 1589
Journal Article
Synthesis, ISSN 0039-7881, 06/2015, Volume 47, Issue 11, pp. 1593 - 1610
Abstract 9-Substituted phenanthrene-3-carboxylic acids have been reported to have allosteric modulatory activity at the N -methyl- d -aspartate (NMDA)... 
paper | phenanthrenes | Wittig reaction | palladium coupling | NMDA receptor | allosteric modulators | ACIDS | CHEMISTRY, ORGANIC | DERIVATIVES
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 15, pp. 3765 - 3781
Journal Article
ISSN 1477-0520, 4/2016, Volume 14, Issue 15, pp. 3765 - 3781
A series of 1′-(6-aminopurin-9-yl)-1′-deoxy- N -methyl-β- d -ribofuranuronamides that were characterised by 2-dialkylamino-7-methyloxazolo[4,5- b... 
Journal Article
ISSN 1477-0520, 2/2016, Volume 14, Issue 6, pp. 257 - 289
Syntheses of (1 RS ,2 SR ,6 SR )-2-alkoxymethyl-, 2-hetaryl-, and 2-(hetarylmethyl)-7-arylmethyl-4,7-diaza-9-oxabicyclo[4.3.0]nonan-8-ones, of interest as... 
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 06/2015, Volume 56, Issue 23, pp. 3255 - 3258
A dihydroxyepoxide analogous to that proposed as a late intermediate in the biosynthesis of phomactin A was prepared by reduction of the corresponding... 
Epoxide cleavage | Natural products | Macrocyclisation | Diastereoselectivity | TPAP oxidation | CORE | TRICYCLIC FURANOCHROMAN | ANTAGONIST | MAGNESIUM BROMIDE | CHEMISTRY, ORGANIC | REARRANGEMENTS | ALCOHOLS | MILD | OXIDANT | TETRAPROPYLAMMONIUM PERRUTHENATE | PRECURSORS | Structure | Crystals
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 01/2019, Volume 159, pp. 140 - 153
-methyl- -aspartate receptors (NMDARs) have multiple prominent roles in CNS function but their excessive or insufficient activity contributes to... 
N-methyl-d-aspartate | C-terminal domain | Phosphorylation | Desensitization | Fluorescence resonance energy transfer | Allosteric modulators | N-methyl-D-aspartate | MECHANISM | D-ASPARTATE RECEPTORS | SUBUNITS | IDENTIFICATION | EXCITOTOXICITY | CALMODULIN | PHARMACOLOGY & PHARMACY | PREGNENOLONE-SULFATE | NONCOMPETITIVE INHIBITION
Journal Article
Neuropharmacology, ISSN 0028-3908, 10/2017, Volume 125, pp. 64 - 79
Journal Article