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1. Full Text Replication and shedding of MERS-CoV in upper respiratory tract of inoculated dromedary camels
by Adney, Danielle R and van Doremalen, Neeltje and Brown, Vienna R and Bushmaker, Trenton and Scott, Dana and de Wit, Emmie and Bowen, Richard A and Munster, Vincent J
Emerging Infectious Diseases, ISSN 1080-6040, 12/2014, Volume 20, Issue 12, pp. 1999 - 2005
In 2012, a novel coronavirus associated with severe respiratory disease in humans emerged in the Middle East. Epidemiologic investigations identified dromedary... 
ANTIBODIES | JUNE | INFECTIOUS DISEASES | INFECTION | IMMUNOLOGY | LIVESTOCK | SYNDROME CORONAVIRUS | SAUDI-ARABIA | Coronavirus Infections - diagnosis | Male | Virus Shedding | Antibodies, Viral - blood | Coronavirus Infections - immunology | Respiratory Tract Infections - diagnosis | Camelus - virology | Antibodies, Neutralizing - immunology | Animals | Coronavirus Infections - veterinary | Coronavirus Infections - virology | Virus Replication | Respiratory Tract Infections - immunology | Antibodies, Viral - immunology | Respiratory Tract Infections - virology | Viral Tropism | Respiratory Tract Infections - veterinary | Antibodies, Neutralizing - blood | Middle East Respiratory Syndrome Coronavirus - physiology | RNA | Health aspects | Index Medicus | infection | viruses | camels | coronavirus | zoonoses | MERS-CoV | experimental | Research | inoculation | and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels | Middle East Respiratory Syndrome | zoonosis | dromedary | transmission | upper respiratory tract
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2. Full Text Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques
by Emmie de Wit and Angela L. Rasmussen and Darryl Falzarano and Trenton Bushmaker and Friederike Feldmann and Douglas L. Brining and Elizabeth R. Fischer and Cynthia Martellaro and Atsushi Okumura and Jean Chang and Dana Scott and Arndt G. Benecke and Michael G. Katze and Heinz Feldmann and Vincent J. Munster
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 41, pp. 16598 - 16603
In 2012, a novel betacoronavirus, designated Middle East respiratory syndrome coronavirus or MERS-CoV and associated with severe respiratory disease in humans,... 
Pneumocytes | Pulmonary alveoli | Coronavirus | Lungs | Disease models | Respiratory diseases | Neutrophils | Viruses | Viral RNA | Lesions | DPP4 | Emerging infectious disease | emerging infectious disease | SYSTEM | BATS | VIRUS | AFRICAN-GREEN | MULTIDISCIPLINARY SCIENCES | ANIMAL-MODEL | CLINICAL-FEATURES | PNEUMONIA | Virus Shedding - physiology | Microscopy, Electron, Transmission | Lung - pathology | Severe Acute Respiratory Syndrome - virology | Species Specificity | Macaca mulatta | Lung - virology | Animals | Virion - ultrastructure | Communicable Diseases, Emerging - virology | Severe Acute Respiratory Syndrome - pathology | Virus Replication - physiology | Disease Models, Animal | Physiological aspects | Host-parasite relationships | Rhesus monkey | Coronaviruses | Research | Health aspects | Life Sciences | Neurons and Cognition | Biological Sciences
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3. Full Text Ebola virus stability on surfaces and in fluids in simulated outbreak environments
by Fischer, Robert and Judson, Seth and Miazgowicz, Kerri and Bushmaker, Trenton and Prescott, Joseph and Munster, Vincent J
Emerging Infectious Diseases, ISSN 1080-6040, 2015, Volume 21, Issue 7, pp. 1243 - 1246
We evaluated the stability of Ebola virus on surfaces and in fluids under simulated environmental conditions for the climate of West Africa and for... 
INFECTIOUS DISEASES | TRANSMISSION | IMMUNOLOGY | PERSISTENCE | Animals | Environmental Microbiology | Humans | Surface Properties | Cercopithecus aethiops | Macaca fascicularis | Microbial Viability | Ebolavirus - physiology | Vero Cells | Ebola virus | viruses | environment | Expedited | surfaces | simulated outbreak environments | Dispatch | stability | Ebola Virus Stability on Surfaces and in Fluids in Simulated Outbreak Environments | fluids
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4. Full Text Stability of middle east respiratory syndrome coronavirus in milk
by van Doremalen, Neeltje and Bushmaker, Trenton and Karesh, William B and Munster, Vincent J
Emerging Infectious Diseases, ISSN 1080-6040, 2014, Volume 20, Issue 7, pp. 1263 - 1264
INFECTIOUS DISEASES | IMMUNOLOGY | Camelus - virology | Cattle - virology | Animals | Coronavirus Infections - veterinary | Coronavirus Infections - virology | Middle East Respiratory Syndrome Coronavirus - genetics | Milk - virology | Goats - virology | Medical research | Disease transmission | Medicine, Experimental | Coronaviruses | Research | Properties | Health aspects | Milk | Letter | viruses | Expedited | milk | Middle East respiratory syndrome coronavirus | zoonoses | Letters to the Editor | MERS-CoV | foodborne transmission | stability
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5. Full Text Postmortem stability of Ebola virus
by Prescott, Joseph and Bushmaker, Trenton and Fischer, Robert and Miazgowicz, Kerri and Judson, Seth and Munster, Vincent J
Emerging Infectious Diseases, ISSN 1080-6040, 2015, Volume 21, Issue 5, pp. 856 - 859
The ongoing Ebola virus outbreak in West Africa has highlighted questions regarding stability of the virus and detection of RNA from corpses. We used Ebola... 
INFECTIOUS DISEASES | RISK | TRANSMISSION | IMMUNOLOGY | HEMORRHAGIC-FEVER | CONGO | Cell Line | Humans | Macaca fascicularis | Hemorrhagic Fever, Ebola - transmission | Microbial Viability | Hemorrhagic Fever, Ebola - epidemiology | Ebolavirus - isolation & purification | Africa, Western - epidemiology | Animals | Time Factors | Autopsy | Disease Outbreaks | Hemorrhagic Fever, Ebola - virology | RNA, Viral | Ebolavirus - physiology | Ebola virus | Ebola virus infections | RNA | Health aspects | viruses | Expedited | Postmortem Stability of Ebola Virus | transmission | cynomolgus macaques | West Africa | postmortem stability | Dispatch | outbreak | Ebola hemorrhagic fever | Ebola virus disease
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6. Full Text The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Does Not Replicate in Syrian Hamsters
by Wit, Emmie and Prescott, C.A.J and Baseler, Laura and Bushmaker, Trenton and Thomas, Tina and Lackemeyer, Matthew and Martellaro, Cynthia and Milne-Price, Shauna and Haddock, Elaine and Haagmans, Bart and Feldmann, Heinz and Munster, Vincent
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e69127
textabstractIn 2012 a novel coronavirus, MERS-CoV, associated with severe respiratory disease emerged in the Arabian Peninsula. To date, 55 human cases have... 
MULTIDISCIPLINARY SCIENCES | INFECTION | Immunohistochemistry | Cricetinae | Dipeptidyl Peptidase 4 - metabolism | Humans | Mesocricetus - metabolism | Body Temperature - physiology | Syndrome | Host-Pathogen Interactions | Middle East | Mesocricetus - virology | Animals | Coronavirus Infections - virology | Respiratory Tract Infections - virology | Body Weight - physiology | Virus Replication - physiology | Coronavirus - physiology | Disease Models, Animal | Physiological aspects | Disease transmission | Coronaviruses | Research | Hamsters | Pneumonia | Pathogenesis | Animal diseases | Viruses | Infections | Seroconversion | Virology | Inoculation | Infectious diseases | Respiratory diseases | Penicillin | Aerosols | Fatalities | Lesions | Laboratory animals | Trachea
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7. Full Text Replication and shedding of MERS-CoV in Jamaican fruit bats (Artibeus jamaicensis)
by Munster, Vincent J and Adney, Danielle R and Van Doremalen, Neeltje and Brown, Vienna R and Miazgowicz, Kerri L and Milne-Price, Shauna and Bushmaker, Trenton and Rosenke, Rebecca and Scott, Dana and Hawkinson, Ann and De Wit, Emmie and Schountz, Tony and Bowen, Richard A
Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, p. 21878
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) highlights the zoonotic potential of Betacoronaviruses. Investigations into the origin... 
DROMEDARY CAMELS | VIRUS-INFECTION | PTEROPID BATS | PHYLOGENETIC ANALYSIS | MULTIDISCIPLINARY SCIENCES | HUMAN BETACORONAVIRUS | NEOTROPICAL BATS | TO-HUMAN TRANSMISSION | RESPIRATORY SYNDROME CORONAVIRUS | SAUDI-ARABIA | DIPEPTIDYL PEPTIDASE 4 | Chiroptera - virology | Cricetinae | Dipeptidyl Peptidase 4 - metabolism | Lung - pathology | Receptors, Virus - metabolism | Cercopithecus aethiops | Virus Shedding | Immunity, Innate | Antibodies, Viral - blood | Coronavirus Infections - immunology | Viral Load | Lung - virology | Animals | Coronavirus Infections - veterinary | Coronavirus Infections - virology | Virus Replication | Coronavirus Infections - blood | Vero Cells | Middle East Respiratory Syndrome Coronavirus - physiology
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8. Full Text Nanopore sequencing as a rapidly deployable Ebola outbreak tool
by Hoenen, Thomas and Groseth, Allison and Rosenke, Kyle and Fischer, Robert J and Hoenen, Andreas and Judson, Seth D and Martellaro, Cynthia and Falzarano, Darryl and Marzi, Andrea and Squires, R. Burke and Wollenberg, Kurt R and De Wit, Emmie and Prescott, Joseph and Safronetz, David and Van Doremalen, Neeltje and Bushmaker, Trenton and Feldmann, Friederike and McNally, Kristin and Bolay, Fatorma K and Fields, Barry and Sealy, Tara and Rayfield, Mark and Nichol, Stuart T and Zoon, Kathryn C and Massaquoi, Moses and Munster, Vincent J and Feldmann, Heinz
Emerging Infectious Diseases, ISSN 1080-6040, 02/2016, Volume 22, Issue 2, pp. 331 - 334
Rapid sequencing of RNA/DNA from pathogen samples obtained during disease outbreaks provides critical scientific and public health information. However,... 
INFECTIOUS DISEASES | TRANSMISSION | VIRUS | IMMUNOLOGY | LIBERIA | Genome, Viral | Hemorrhagic Fever, Ebola - microbiology | Disease Outbreaks | Humans | Mutation | Ebolavirus - genetics | Hemorrhagic Fever, Ebola - epidemiology | Nanopores | Sequence Analysis, DNA - methods | Ebola virus | Epidemics | Liberia | Genomics | Ebola virus infections | Development and progression | Genomes | Nucleotide sequencing | Germany | DNA sequencing | Ebolavirus | nanopore sequencing | viruses | Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Response Tool | molecular diagnostic techniques | Dispatch | disease outbreaks | Ebola hemorrhagic fever | high-throughput nucleotide sequencing | DNA | West Africa | Ebola virus disease
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9. Full Text Comparison of the Aerosol Stability of 2 Strains ofZaire ebolavirusFrom the 1976 and 2013 Outbreaks
by Fischer, Robert J and Bushmaker, Trenton and Judson, Seth and Munster, Vincent J
Journal of Infectious Diseases, ISSN 0022-1899, 10/2016, Volume 214, Issue suppl 3, pp. S290 - S293
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10. Full Text Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques
by Falzarano, Darryl and De Wit, Emmie and Rasmussen, Angela L and Feldmann, Friederike and Okumura, Atsushi and Scott, Dana P and Brining, Doug and Bushmaker, Trenton and Martellaro, Cynthia and Baseler, Laura and Benecke, Arndt G and Katze, Michael G and Munster, Vincent J and Feldmann, Heinz
Nature Medicine, ISSN 1078-8956, 10/2013, Volume 19, Issue 10, pp. 1313 - 1317
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) is of global concern: the virus has caused severe respiratory illness, with 111... 
Recombinant Proteins - therapeutic use | Animals | Virus Replication | Antiviral Agents - therapeutic use | Coronavirus Infections - drug therapy | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | Macaca mulatta | Real-Time Polymerase Chain Reaction | Coronavirus - physiology
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11. Full Text Domestic pig unlikely reservoir for MERS-COV
by De Wit, Emmie and Feldmann, Friederike and Horne, Eva and Martellaro, Cynthia and Haddock, Elaine and Bushmaker, Trenton and Rosenke, Kyle and Okumura, Atsushi and Rosenke, Rebecca and Saturday, Greg and Scott, Dana and Feldmann, Heinz
Emerging Infectious Diseases, ISSN 1080-6040, 06/2017, Volume 23, Issue 6, pp. 985 - 988
We tested the suitability of the domestic pig as a model for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Inoculation did not cause... 
ANIMAL-MODELS | INFECTIOUS DISEASES | INFECTION | IMMUNOLOGY | BINDING | RESPIRATORY SYNDROME CORONAVIRUS | Disease Reservoirs - veterinary | Animals | Coronavirus Infections - veterinary | Coronavirus Infections - virology | Swine | Swine Diseases - virology | Disease Reservoirs - virology | Host Specificity | Middle East Respiratory Syndrome Coronavirus - physiology | Physiological aspects | DPP4 | Domestic Pig Unlikely Reservoir for MERS-CoV | domestic pig | pigs | animal models | viruses | United States | Dispatch | Middle East respiratory syndrome coronavirus | zoonoses | MERS-CoV | dipeptidyl peptidase 4
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12. Full Text Foodborne Transmission of Nipah Virus in Syrian Hamsters
by de Wit, Emmie and Prescott, Joseph and Falzarano, Darryl and Bushmaker, Trenton and Scott, Dana and Feldmann, Heinz and Munster, Vincent J
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 3, p. e1004001
Since 2001, outbreaks of Nipah virus have occurred almost every year in Bangladesh with high case-fatality rates. Epidemiological data suggest that in... 
BATS | ROUTE | VIROLOGY | MALAYSIA | PARAMYXOVIRUS | MICROBIOLOGY | CENTRAL-NERVOUS-SYSTEM | BANGLADESH | INFECTION | FLYING-FOXES | MODEL | PARASITOLOGY | Cricetinae | Animals | Mesocricetus | Drinking | Female | Nipah Virus | Foodborne Diseases - virology | Arecaceae - virology | Henipavirus Infections - transmission | Microbiological research | Henipaviruses | Disease transmission | Zoological research | Host-parasite relationships | Research | Hamsters | Health aspects | Confidence intervals | Encephalitis | Hypotheses | Food contamination & poisoning | Disease | Rodents | Respiratory diseases | Infections | Epidemiology | Zoonoses
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13. Full Text Rapid Nipah virus entry into the central nervous system of hamsters via the olfactory route
by Munster, Vincent J and Prescott, Joseph B and Bushmaker, Trenton and Long, Dan and Rosenke, Rebecca and Thomas, Tina and Scott, Dana and Fischer, Elizabeth R and Feldmann, Heinz and De Wit, Emmie
Scientific Reports, ISSN 2045-2322, 2012, Volume 2, Issue 1, p. 736
Encephalitis is a hallmark of Nipah virus (NiV) infection in humans. The exact route of entry of NiV into the central nervous system (CNS) is unknown. Here, we... 
TRANSMISSION | PATHWAY | ENCEPHALITIS | MULTIDISCIPLINARY SCIENCES | HOST | INFECTION | BANGLADESH | CLINICAL-FEATURES | OUTBREAK | Immunohistochemistry | Microscopy, Electron, Transmission | Neurons - pathology | Neurons - virology | Cricetinae | Olfactory Bulb - pathology | Olfactory Mucosa - virology | Virus Internalization | Nipah Virus - physiology | Animals | Olfactory Bulb - virology | Olfactory Mucosa - pathology | Central Nervous System - virology | Henipavirus Infections - virology | Encephalitis | Cortex (olfactory) | Central nervous system | Nervous system | Epithelium | Electron microscopy | Smell | Transmission electron microscopy | Neurodegeneration | Extravasation | Respiratory diseases | Plasma cells | Olfactory bulb | Olfactory epithelium | Axonal transport | Cortex (temporal)
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14. Full Text Treatment with interferon-alpha 2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques
by Falzarano, D and de Wit, E and Rasmussen, AL and Feldmann, F and Okumura, A and Scott, DP and Brining, D and Bushmaker, T and Martellaro, C and Baseler, L and Benecke, AG and Katze, MG and Munster, VJ and Feldmann, H
NATURE MEDICINE, ISSN 1078-8956, 10/2013, Volume 19, Issue 10, pp. 1313 - 1313
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) is of global concern: the virus has caused severe respiratory illness, with 111... 
MEDICINE, RESEARCH & EXPERIMENTAL | TGF-BETA | SONIC HEDGEHOG | BIOCHEMISTRY & MOLECULAR BIOLOGY | INFLUENZA | SARS | PNEUMONIA | ACUTE RESPIRATORY SYNDROME | HUMAN CORONAVIRUS | CELL BIOLOGY | GROWTH | CONVALESCENT PLASMA | EXPRESSION | Data processing | Life Sciences | Neurons and Cognition
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15. Full Text Safety of recombinant VSV-Ebola virus vaccine vector in pigs
by De Wit, Emmie and Marzi, Andrea and Bushmaker, Trenton and Brining, Doug and Scott, Dana and Richt, Juergen A and Geisbert, Thomas W and Feldmann, Heinz
Emerging Infectious Diseases, ISSN 1080-6040, 2015, Volume 21, Issue 4, pp. 702 - 704
The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector... 
NONHUMAN-PRIMATES | GLYCOPROTEINS | INFECTIOUS DISEASES | IMMUNOLOGY | VESICULAR STOMATITIS-VIRUS | Immunization | Genetic Vectors - administration & dosage | Genetic Vectors - immunology | Immunoglobulin G - blood | Vesicular stomatitis Indiana virus - genetics | Viral Vaccines - genetics | Genetic Vectors - adverse effects | Virus Shedding | Ebolavirus - genetics | Viral Vaccines - adverse effects | Antibodies, Viral - blood | Genetic Vectors - genetics | Viral Vaccines - administration & dosage | Animals | Virus Replication | Immunoglobulin G - immunology | Swine | DNA, Recombinant | Antibodies, Viral - immunology | Viral Vaccines - immunology | Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs | Ebola virus | pigs | viruses | VSV vaccine | vaccines | safety | VSV | recombinant VSV–Ebola virus vaccine vector | Dispatch | zoonoses | vesicular stomatitis viruses | recombinant VSV Ebola virus vaccine vector
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16. Full Text A single-dose ChAdOx1-vectored vaccine provides complete protection against Nipah Bangladesh and Malaysia in Syrian golden hamsters
by van Doremalen, N and Lambe, T and Sebastian, S and Bushmaker, T and Fischer, R and Feldmann, F and Haddock, E and Letko, M and Avanzato, VA and Rissanen, I and LaCasse, R and Scott, D and Bowden, TA and Gilbert, S and Munster, V
PLOS NEGLECTED TROPICAL DISEASES, ISSN 1935-2735, 06/2019, Volume 13, Issue 6, p. e0007462
Nipah virus (NiV) is a highly pathogenic re-emerging virus that causes outbreaks in South East Asia. Currently, no approved and licensed vaccine or antivirals... 
BATS | VIRUS TRANSMISSION | IMMUNOGENICITY | SAFETY | SURFACE | HUMANS | DATE PALM SAP | INFECTION | OUTBREAK | HENIPAVIRUSES | PARASITOLOGY | TROPICAL MEDICINE | Vaccines | Tetracyclines | Hamsters | Lung diseases | Vaccination | Tetracycline | RNA | Laboratories | Antibodies | Outbreaks | Viruses | Biology | Lethality | Infections | Hybridization | Tissues | Animal tissues | Genetics | Nipah virus | Protection | Pathogens | Encephalitis | Glycoprotein | Glycoproteins | Nucleic acids | Ribonucleic acid--RNA | Disease control | Survival | Strain | Virology | Infectious diseases | Animals | Lungs | Fatalities | Brain damage | Ribonucleic acid
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17. Full Text Host species restriction of middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4
by van Doremalen, Neeltje and Miazgowicz, Kerri L and Milne-Price, Shauna and Bushmaker, Trenton and Robertson, Shelly and Scott, Dana and Kinne, Joerg and McLellan, Jason S and Zhu, Jiang and Munster, Vincent J
Journal of Virology, ISSN 0022-538X, 2014, Volume 88, Issue 16, pp. 9220 - 9232
Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012. Recently, the MERS-CoV receptor dipeptidyl peptidase 4 (DPP4) was identified and the... 
DROMEDARY CAMELS | TROPISM | VIROLOGY | SUSCEPTIBILITY | BINDING DOMAIN | SPIKE PROTEIN | MERS-COV | INFECTION | CLINICAL-FEATURES | PNEUMONIA | FUNCTIONAL RECEPTOR | Livestock - metabolism | Dipeptidyl Peptidase 4 - metabolism | Receptors, Virus - metabolism | Virus Replication - genetics | Humans | Sheep - virology | Ferrets - virology | Middle East | Macaca mulatta - virology | Macaca mulatta - metabolism | Coronavirus - metabolism | Cattle | Livestock - virology | Viral Tropism | Vero Cells | Respiratory Syncytial Viruses - metabolism | Primates - metabolism | Cell Line | Cricetinae | Coronavirus - pathogenicity | Ferrets - metabolism | Mice, Inbred C57BL | Host Specificity | Goats - virology | Primates - virology | Camelus - metabolism | Goats - metabolism | Camelus - virology | Animals | Cell Line, Tumor | Protein Binding | Sheep - metabolism | Mice | Respiratory Syncytial Viruses - pathogenicity | Virus-Cell Interactions
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