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Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 03/2016, Volume 99, Issue 3, pp. 285 - 297
Journal Article
Osteoarthritis and Cartilage, ISSN 1063-4584, 04/2019, Volume 27, pp. S294 - S295
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 11/2009, Volume 86, Issue 5, pp. 507 - 510
Drug repositioning refers to the discovery of alternative uses for drugs—uses that are different from that for which the drugs were originally intended. One... 
REDUCTASE | PHARMACOLOGY & PHARMACY | INHIBITION | Drug Discovery - methods | Clinical Trials as Topic | Pharmaceutical Preparations - administration & dosage | Drug Industry - methods | Humans | Drug Design
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 12/2013, Volume 94, Issue 6, pp. 627 - 629
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 510, Issue 7504, pp. 283 - 287
Deregulation of lysine methylation signalling has emerged as a common aetiological factor in cancer pathogenesis, with inhibitors of several histone lysine... 
LUNG-CANCER | ACTIVATION | PROTEIN | K-RAS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | KINASE | PANCREATIC INTRAEPITHELIAL NEOPLASIA | GROWTH-FACTOR | HISTONE METHYLTRANSFERASE | PROGRESSION | Adenocarcinoma - pathology | Pancreatic Neoplasms - metabolism | Adenocarcinoma of Lung | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Oncogene Protein p21(ras) - metabolism | MAP Kinase Kinase Kinases - chemistry | Adenocarcinoma - metabolism | Cell Transformation, Neoplastic - genetics | MAP Kinase Kinase Kinase 2 - chemistry | Adenocarcinoma - genetics | Lysine - metabolism | Disease Models, Animal | Lung Neoplasms - genetics | MAP Kinase Kinase Kinase 2 - metabolism | Lung Neoplasms - enzymology | Protein Phosphatase 2 - antagonists & inhibitors | Signal Transduction | Pancreatic Neoplasms - pathology | Adenocarcinoma - enzymology | Pancreatic Neoplasms - enzymology | Pancreatic Neoplasms - genetics | MAP Kinase Kinase Kinases - metabolism | Cell Transformation, Neoplastic - metabolism | Proto-Oncogene Proteins A-raf - metabolism | Animals | Histone-Lysine N-Methyltransferase - metabolism | Protein Phosphatase 2 - metabolism | Cell Line, Tumor | Mice | Cell Transformation, Neoplastic - pathology | Methylation | Mitogen-Activated Protein Kinases - metabolism | Oncogene Protein p21(ras) - genetics | Physiological aspects | Research | Lysine | Oncology, Experimental | Cancer | DNA methylation | Peptides | Kinases | Rodents | Tumors
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 06/2012, Volume 91, Issue 6, pp. 949 - 952
Internet‐accessible computing power and data‐sharing mandates now enable researchers to interrogate thousands of publicly available databases containing... 
PHARMACOLOGY & PHARMACY | CANCER | CHEMOTHERAPY | INFORMATICS | Computers | Animals | Pharmacology - trends | Humans | Computational Biology - trends | Drug Discovery - trends | Databases, Genetic | Translational Medical Research - trends | Databases, Factual | Technology application | Usage | Computational biology
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 05/2018, Volume 138, Issue 5, pp. S161 - S161
Journal Article
Journal Article
CPT: Pharmacometrics & Systems Pharmacology, ISSN 2163-8306, 10/2015, Volume 4, Issue 10, pp. 576 - 584
A central premise in systems pharmacology is that structurally similar compounds have similar cellular responses; however, this principle often does not hold.... 
Hypothesis testing | Similarity measures | Genomics | Conflicts of interest | Pharmacology | Genomes | Gene expression | Chemical compounds | Physical properties | Drug dosages | Biological activity | Original
Journal Article
Journal of Surgical Research, ISSN 0022-4804, 2014, Volume 186, Issue 2, pp. 558 - 559
Journal Article
Science Translational Medicine, ISSN 1946-6234, 09/2011, Volume 3, Issue 102
Journal Article
Journal Article
CPT: Pharmacometrics & Systems Pharmacology, ISSN 2163-8306, 11/2016, Volume 5, Issue 11, pp. 599 - 607
Journal Article