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Bioinformatics, ISSN 1367-4803, 10/2016, Volume 32, Issue 20, pp. 3207 - 3209
PhenoScanner is a curated database of publicly available results from large-scale genetic association studies. This tool aims to facilitate 'phenome scans',... 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Genetic Variation | Phenotype | Genetic Association Studies | Humans | Genotype | Polymorphism, Single Nucleotide | Software | Databases, Factual | Index Medicus | Applications Notes
Journal Article
by Fuchsberger, Christian and Flannick, Jason and Teslovich, Tanya M and Mahajan, Anubha and Agarwala, Vineeta and Gaulton, Kyle J and Ma, Clement and Fontanillas, Pierre and Moutsianas, Loukas and McCarthy, Davis J and Rivas, Manuel A and Perry, John R. B and Sim, Xueling and Blackwell, Thomas W and Robertson, Neil R and Rayner, N. William and Cingolani, Pablo and Locke, Adam E and Fernandez Tajes, Juan and Highland, Heather M and Dupuis, Josee and Chines, Peter S and Lindgren, Cecilia M and Hartl, Christopher and Jackson, Anne U and Chen, Han and Huyghe, Jeroen R and van de Bunt, Martijn and Pearson, Richard D and Kumar, Ashish and Müller-Nurasyid, Martina and Grarup, Niels and Stringham, Heather M and Gamazon, Eric R and Lee, Jaehoon and Chen, Yuhui and Scott, Robert A and Below, Jennifer E and Chen, Peng and Huang, Jinyan and Go, Min Jin and Stitzel, Michael L and Pasko, Dorota and Parker, Stephen C. J and Varga, Tibor V and Green, Todd and Beer, Nicola L and Day-Williams, Aaron G and Ferreira, Teresa and Fingerlin, Tasha and Horikoshi, Momoko and Hu, Cheng and Huh, Iksoo and Ikram, Mohammad Kamran and Kim, Bong-Jo and Kim, Yongkang and Kim, Young Jin and Kwon, Min-Seok and Lee, Juyoung and Lee, Selyeong and Lin, Keng-Han and Maxwell, Taylor J and Nagai, Yoshihiko and Wang, Xu and Welch, Ryan P and Yoon, Joon and Zhang, Weihua and Barzilai, Nir and Voight, Benjamin F and Han, Bok-Ghee and Jenkinson, Christopher P and Kuulasmaa, Teemu and Kuusisto, Johanna and Manning, Alisa and Ng, Maggie C. Y and Palmer, Nicholette D and Balkau, Beverley and Stancáková, Alena and Abboud, Hanna E and Boeing, Heiner and Gieaitis, Vilmantas and Prabhakaran, Dorairaj and Gottesman, Omri and Scott, James and Carey, Jason and Kwan, Phoenix and Grant, George and Smith, Joshua D and Neale, Benjamin M and Purcell, Shaun and Butterworth, Adam S and Howson, Joanna M. M and Lee, Heung Man and Lu, Yingchang and Kwak, Soo-Heon and Zhao, Wei and Danesh, John and Lam, Vincent K. L and Park, Kyong Soo and Saleheen, Danish and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2016, Volume 536, Issue 7614, pp. 41 - +
Journal Article
by Wood, Angela M and Kaptoge, Stephen and Butterworth, Adam S and Butterworth, Adam and Willeit, Peter and Warnakula, Samantha and Bolton, Thomas and Paige, Ellie and Paul, Dirk S and Sweeting, Michael and Burgess, Stephen and Bell, Steven and Astle, William and Stevens, David and Koulman, Albert and Selmer, Randi M and Verschuren, Monique and Verschuren, W M Monique and Sato, Shinichi and Njølstad, Inger and Woodward, Mark and Salomaa, Veikko and Nordestgaard, Børge G and Yeap, Bu B and Fletcher, Astrid and Melander, Olle and Kuller, Lewis H and Balkau, Beverley and Marmot, Michael and Koenig, Wolfgang and Casiglia, Edoardo and Cooper, Cyrus and Cooper, Jackie A and Arndt, Volker and Franco, Oscar H and Wennberg, Maria and Wennberg, Patrik and Gallacher, John and de la Cámara, Agustín Gómez and Völzke, Henry and Dahm, Christina C and Dale, Caroline E and Bergmann, Manuela M and Bergmann, Manuela and Crespo, Carlos J and Crespo, Carlos and van der Schouw, Yvonne T and Kaaks, Rudolf and Simons, Leon A and Lagiou, Pagona and Schoufour, Josje D and Boer, Jolanda M A and Boer, Jolanda M.A and Key, Timothy J and Rodriguez, Beatriz and Rodriguez, Carlos J and Moreno-Iribas, Conchi and Davidson, Karina W and Taylor, James O and Sacerdote, Carlotta and Wallace, Robert B and Quiros, J Ramon and Quiros, J. Ramon and Tumino, Rosario and Blazer, Dan G and Linneberg, Allan and Daimon, Makoto and Panico, Salvatore and Howard, Barbara and Skeie, Guri and Strandberg, Timo and Weiderpass, Elisabete and Nietert, Paul J and Psaty, Bruce M and Kromhout, Daan and Salamanca-Fernandez, Elena and Kiechl, Stefan and Krumholz, Harlan M and Grioni, Sara and Palli, Domenico and Huerta, José M and Price, Jackie and Sundström, Johan and Arriola, Larraitz and Arima, Hisatomi and Travis, Ruth C and Panagiotakos, Demosthenes B and Karakatsani, Anna and Trichopoulou, Antonia and Kühn, Tilman and Grobbee, Diederick E and Barrett-Connor, Elizabeth and van Schoor, Natasja and Boeing, Heiner and Overvad, Kim and Kauhanen, Jussi and Wareham, Nick and Langenberg, Claudia and Forouhi, Nita and Després, Jean-Pierre and ... and Emerging Risk Factors Collabora and Emerging Risk Factors Collaboration/EPIC-CVD/UK Biobank Alcohol Study Group and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet
The Lancet, ISSN 0140-6736, 04/2018, Volume 391, Issue 10129, pp. 1513 - 1523
Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk... 
MORTALITY | STROKE | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | CHOLESTEROL | PATTERN | CARDIOVASCULAR-DISEASE | CORONARY-HEART-DISEASE | ASSOCIATION | CANCER | BLOOD-PRESSURE | Cardiovascular Diseases - etiology | Prospective Studies | Humans | Middle Aged | Female | Male | Alcohol Drinking - adverse effects | Alcohol Drinking - mortality | Drinking of alcoholic beverages | Myocardial infarction | Heart attacks | Sex | Income | Alcohol | Cardiovascular disease | Dosage | Risk factors | Guidelines | Alcohol use | Aorta | Heart diseases | Age | Consumption | Medical research | Cerebral infarction | Data analysis | Stroke | Life expectancy | Risk groups | Thresholds | Drinking behavior | Mortality | Diabetes mellitus | Health risks | Data processing | Risk analysis | Disease control | Cholesterol | Studies | Lipoproteins | Life span | Collaboration | Infarction | Diabetes | Cardiovascular diseases | Health risk assessment | Smoking | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Beroendelära | Public Health, Global Health, Social Medicine and Epidemiology | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Substance Abuse | Health Sciences | Human Nutrition & Health | Human Nutrition | Afdeling Humane voeding | Humane Voeding | Humane Voeding & Gezondheid | Human Nutrition (HNE)
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, pp. e112483 - e112483
Background: Short telomeres have been linked to various age-related diseases. We aimed to assess the association of telomere length with incident type 2... 
OXIDATIVE STRESS | HEART-DISEASE | MYOCARDIAL-INFARCTION | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | ADULTS | FOLLOW-UP | LONGITUDINAL FINDINGS | INCIDENT CANCER | ASSOCIATION | CANCER-MORTALITY | Leukocytes - pathology | Prospective Studies | Age Factors | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | Diabetes Mellitus, Type 2 - metabolism | Motor Activity | Telomere Shortening | C-Reactive Protein - metabolism | Adult | Female | Telomere - metabolism | Waist-Hip Ratio | Body Mass Index | Risk Factors | Proportional Hazards Models | Alcohol Drinking - physiopathology | Social Class | Telomere - chemistry | Sex Factors | Cholesterol, HDL - blood | Aged | Diabetes Mellitus, Type 2 - pathology | Leukocytes - metabolism | Type 2 diabetes | Development and progression | Chromosomes | Risk factors | Cholesterol | Target marketing | Oxidative stress | C-reactive protein | Physical activity | Laboratories | Variability | Risk | Population studies | Alcohol | Epidemiology | Confidence intervals | Regression models | Atherosclerosis | Quartiles | Telomerase | Public health | Deoxyribonucleic acid--DNA | Economic models | Sensitivity analysis | Statistical analysis | Diabetes mellitus | Health risks | Hazards | Regression analysis | Primary care | Hip | Meta-analysis | Medicine | Studies | Polymerase chain reaction | Neurology | Telomeres | Dilution | Socioeconomic factors | Insulin resistance | Diabetes | Genetic testing | Smoking | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Bioinformatics, ISSN 1367-4803, 06/2019
SUMMARYPhenoScanner is a curated database of publicly available results from large-scale genetic association studies in humans. This online tool facilitates... 
Journal Article
by Marouli, Eirini and Graff, Mariaelisa and Medina-Gomez, Carolina and Lo, Ken Sin and Wood, Anew R and Kjaer, Troels R and Fine, Rebecca S and Lu, Yingchang and Schurmann, Claudia and Highland, Heather M and Rüeger, Sina and Thorleifsson, Gudmar and Justice, Anne E and Lamparter, David and Stirrups, Kathleen E and Turcot, Valérie and Young, Kristin L and Winkler, Thomas W and Esko, Tõnu and Karaderi, Tugce and Locke, Adam E and Masca, Nicholas G. D and Ng, Maggie C. Y and Mudgal, Poorva and Rivas, Manuel A and Vedantam, Sailaja and Mahajan, Anubha and Guo, Xiuqing and Abecasis, Goncalo and Aben, Katja K and Adair, Linda S and Alam, Dewan S and Albrecht, Eva and Allin, Kristine H and Allison, Matthew and Amouyel, Philippe and Appel, Emil V and Arveiler, Dominique and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Banas, Bernhard and Bang, Lia E and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bonnycastle, Lori L and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Burt, Amber A and Butterworth, Adam S and Carey, David J and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Cocca, Massimiliano and Collins, Francis S and Cook, James P and Corley, Janie and Galbany, Jordi Corominas and Cox, Amanda J and Cuellar-Partida, Gabriel and Danesh, John and Davies, Gail and de Bakker, Paul I. W and de Borst, Gert J and de Denus, Simon and de Groot, Mark C. H and de Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and den Hollander, Anneke I and Dennis, Joe G and Di Angelantonio, Emanuele and nos, Fotios and Du, Mengmeng and Dunning, Alison M and Easton, Douglas F and Ebeling, Tapani and Edwards, Todd L and Ellinor, Patrick T and Elliott, Paul and Evangelou, Evangelos and Farmaki, Aliki-Eleni and Faul, Jessica D and ... and EPIC-CVD Consortium and GoT2D Genes Consortium and MAGIC Investigators and Global Lipids Genetics Consortium and EPIC-InterAct Consortium and ReproGen Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and CHD Exome+ Consortium and The EPIC-InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2017, Volume 542, Issue 7640, pp. 186 - 190
Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so... 
MULTIDISCIPLINARY SCIENCES | MISSING HERITABILITY | GENETIC ARCHITECTURE | INTERLEUKIN-11 | MICE | MUTATIONS | GENOME-WIDE ASSOCIATION | Cell Adhesion Molecules - genetics | Gene Frequency - genetics | Humans | Glycoproteins - metabolism | Male | Intercellular Signaling Peptides and Proteins - metabolism | Hedgehog Proteins - genetics | Proteolysis | NADPH Oxidases - genetics | Adult | Female | Interleukin-11 Receptor alpha Subunit - genetics | Somatomedins - metabolism | Glycosaminoglycans - biosynthesis | Glycoproteins - genetics | Multifactorial Inheritance - genetics | Procollagen N-Endopeptidase - genetics | Intercellular Signaling Peptides and Proteins - genetics | Interferon Regulatory Factors - genetics | Proteoglycans - biosynthesis | NADPH Oxidase 4 | Body Height - genetics | Genome, Human - genetics | Phenotype | Receptors, Androgen - genetics | Alleles | Genetic Variation - genetics | Pregnancy-Associated Plasma Protein-A - metabolism | ADAMTS Proteins - genetics | Stature | Genetic aspects | Observations | Genetic variation | Studies | Datasets | Disease | Genes | Deoxyribonucleic acid--DNA | Index Medicus | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Health Sciences
Journal Article