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index medicus (55) 55
humans (53) 53
multiple sclerosis (39) 39
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middle aged (19) 19
neurology (18) 18
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multiple sclerosis - genetics (7) 7
natalizumab (7) 7
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brain (6) 6
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dose-response relationship, drug (5) 5
endothelial cells (5) 5
health aspects (5) 5
interferon-beta (5) 5
multiple sclerosis - cerebrospinal fluid (5) 5
multiple sclerosis - diagnosis (5) 5
multiple sclerosis - pathology (5) 5
myelin-oligodendrocyte glycoprotein - immunology (5) 5
nervous system (5) 5
neuromyelitis optica (5) 5
physiological aspects (5) 5
progressive multifocal leukoencephalopathy (5) 5
proteins (5) 5
rna, messenger - metabolism (5) 5
activation (4) 4
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endothelial cells - drug effects (4) 4
function and dysfunction of the nervous system (4) 4
immunoglobulin g - blood (4) 4
immunotherapy (4) 4
interferon-beta - administration & dosage (4) 4
interferon-beta - therapeutic use (4) 4
medicine, experimental (4) 4
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monocyte chemoattractant protein-1 (4) 4
multiple sclerosis - metabolism (4) 4
myelin oligodendrocyte glycoprotein antibodies (4) 4
myelin-oligodendrocyte glycoprotein (4) 4
neuromyelitis optica spectrum disorders (4) 4
oligoclonal bands - cerebrospinal fluid (4) 4
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polymorphism, single nucleotide (4) 4
psychopharmacology (4) 4
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1. Full Text Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study
by Kappos, Ludwig and Bar-Or, Amit and Cree, Bruce A C and Fox, Robert J and Giovannoni, Gavin and Gold, Ralf and Vermersch, Patrick and Arnold, Douglas L and Arnould, Sophie and Scherz, Tatiana and Wolf, Christian and Wallström, Erik and Dahlke, Frank and Achiron, Anat and Achtnichts, Lutz and Agan, Kadriye and Akman-Demir, Gulsen and Allen, Alison B and Antel, Jack P and Antiguedad, Alfredo Rodriguez and Apperson, Michelle and Applebee, Angela M and Ayuso, Guillermo Izquierdo and Baba, Masayuki and Bajenaru, Ovidiu and Balasa, Rodica and Balci, Belgin Petek and Barnett, Michael and Bass, Ann and Becker, Veit U and Bejinariu, Mihaela and Bergh, Florian Then and Bergmann, Arnfin and Bernitsas, Evanthia and Berthele, Achim and Bhan, Virender and Bischof, Felix and Bjork, Randall John and Blevins, Gregg and Boehringer, Matthias and Boerner, Thomas and Bonek, Robert and Bowen, James D and Bowling, Allen and Boyko, Alexey N and Boz, Cavit and Bracknies, Vera and Braune, Stefan and Brescia Morra, Vincenzo and Brochet, Bruno and Brola, Waldemar and Brownstone, Paul Kenneth and Brozman, Miroslav and Brunet, Donald and Buraga, Ioan and Burnett, Margaret and Buttmann, Mathias and Butzkueven, Helmut and Cahill, Jonathan and Calkwood, Jonathan C and Camu, William and Cascione, Mark and Castelnovo, Giovani and Centonze, Diego and Cerqueira, Joao and Chan, Andrew and Cimprichova, Andrea and Cohan, Stanley and Comi, Giancarlo and Conway, Jill and Cooper, Joanna A and Corboy, John and Correale, Jorge and Costell, Brian and Cottrell, David A and Coyle, Patricia K and Craner, Matthew and Cui, Liying and Cunha, Luis and Czlonkowska, Anna and da Silva, Ana Martins and de Sa, Joao and de Seze, Jérôme and Debouverie, Marc and Debruyne, Jan and Decoo, Danny and Defer, Gilles and Derfuss, Tobias and Deri, Norma H and Dihenia, Bhupesh and Dioszeghy, Peter and Donath, Vladimir and Dubois, Benedicte and Duddy, Martin and Duquette, Pierre and Edan, Gilles and Efendi, Husnu and Elias, Stanton and Emrich, Peter J and Estruch, Bonaventura Casanova and ... and EXPAND Clinical Investigators and Institute of Neuroscience and Physiology and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institutionen för neurovetenskap och fysiologi
The Lancet, ISSN 0140-6736, 03/2018, Volume 391, Issue 10127, pp. 1263 - 1273
No treatment has consistently shown efficacy in slowing disability progression in patients with secondary progressive multiple sclerosis (SPMS). We assessed... 
DISABILITY | MEDICINE, GENERAL & INTERNAL | INTERFERON BETA-1B | FINGOLIMOD | CLINICAL-TRIALS | Double-Blind Method | Humans | Middle Aged | Multiple Sclerosis, Chronic Progressive - pathology | Male | Treatment Outcome | Disease Progression | Dose-Response Relationship, Drug | Young Adult | Azetidines - therapeutic use | Adolescent | Benzyl Compounds - therapeutic use | Adult | Female | Multiple Sclerosis, Chronic Progressive - drug therapy | Cohort Studies | Multiple sclerosis | Analysis | Hypertension | Edema | Cardiac arrhythmia | Liver | Transaminase | Clinical trials | Risk reduction | Activation | Patients | Modulators | Sphingosine 1-phosphate | Studies | Bradycardia | Lymphopenia | Varicella | Population | Titration | Interferon | Safety | Convulsions | Heart diseases | Pharmaceuticals | Index Medicus | Abridged Index Medicus | Neurologi | Neurology
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2. Full Text Fumaric acid esters do not reduce inflammatory NF-κB/p65 nuclear translocation, ICAM-1 expression and T-cell adhesiveness of human brain microvascular endothelial cells
by Haarmann, Axel and Nehen, Mathias and Deiß, Annika and Buttmann, Mathias
International Journal of Molecular Sciences, ISSN 1661-6596, 08/2015, Volume 16, Issue 8, pp. 19086 - 19095
Dimethyl fumarate (DMF) is approved for disease-modifying treatment of patients with relapsing-remitting multiple sclerosis. Animal experiments suggested that... 
P38 mitogen-activated protein kinase | NF-κB | Monomethyl fumarate | Multiple sclerosis | Blood-brain barrier | Dimethyl fumarate | Cell adhesion | Endothelial cells | blood-brain barrier | DRUG | endothelial cells | multiple sclerosis | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIMETHYLFUMARATE | BARRIER INTEGRITY | CHEMISTRY, MULTIDISCIPLINARY | VCAM-1 | NF-kappa B | MULTIPLE-SCLEROSIS | GENE | cell adhesion | MONOMETHYLFUMARATE | dimethyl fumarate | p38 mitogen-activated protein kinase | PROTEINS | POTENT INDUCER | monomethyl fumarate | Endothelium, Vascular - cytology | Human Umbilical Vein Endothelial Cells | Maleates - pharmacology | Humans | Endothelium, Vascular - drug effects | Microvessels - immunology | Brain - blood supply | Dimethyl Fumarate - pharmacology | T-Lymphocytes - drug effects | Transcription Factor RelA - immunology | Immunosuppressive Agents - pharmacology | Endothelium, Vascular - immunology | Intercellular Adhesion Molecule-1 - analysis | Microvessels - cytology | Cell Line | Intercellular Adhesion Molecule-1 - immunology | Interleukin-1beta - immunology | Microvessels - drug effects | Cell Adhesion - drug effects | Brain - drug effects | Transcription Factor RelA - analysis | Active Transport, Cell Nucleus - drug effects | Fumarates - pharmacology | Multiple Sclerosis - immunology | T-Lymphocytes - immunology | Brain - immunology | Multiple Sclerosis - drug therapy | Index Medicus
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3. Full Text Neue Studien zu Multipler Sklerose und Neuromyelitis optica
by Buttmann, Mathias
DNP - Der Neurologe und Psychiater, ISSN 1616-2455, 9/2015, Volume 16, Issue 9, pp. 18 - 19
In der aktuellen Studienübersicht beleuchtet PD Dr. Mathias Buttmann den prognostischen Wert des Liquors beim klinisch isolierten Syndrom, fasst Daten zur... 
Neurology | Medicine & Public Health | Psychopharmacology | Psychotherapy | Psychiatry
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4. Full Text Multiple Sklerose: Diagnostisch und therapeutisch tut sich einiges
by Buttmann, Mathias and Haarmann, Axel
DNP - Der Neurologe & Psychiater, ISSN 1616-2455, 06/2019, Volume 20, Issue 3, pp. 20 - 22
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5. Full Text Sind Neurofilament-Leichtketten im Plasma bald das CRP des Neuroimmunologen?
by Haarmann, Axel and Buttmann, Mathias
DNP - Der Neurologe & Psychiater, ISSN 1616-2455, 06/2019, Volume 20, Issue 3, pp. 22 - 24
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6. Full Text Gibt es die wirksamste MS-Therapie beim Hämatoonkologen?
by Haarmann, Axel and Buttmann, Mathias
DNP - Der Neurologe & Psychiater, ISSN 1616-2455, 06/2019, Volume 20, Issue 3, pp. 28 - 29
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7. Full Text Endlich frischer Wind! — Komplementärtherapie mit neuroprotektivem Bronchodilatator?
by Haarmann, Axel and Buttmann, Mathias
DNP - Der Neurologe & Psychiater, ISSN 1616-2455, 06/2019, Volume 20, Issue 3, pp. 24 - 26
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8. Full Text Ist eine Multiple Sklerose zu schnell diagnostiziert?
by Haarmann, Axel and Buttmann, Mathias
DNP - Der Neurologe & Psychiater, ISSN 1616-2455, 06/2019, Volume 20, Issue 3, pp. 26 - 27
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9. Full Text MS-Therapien im Kindesalter: Behandeln wir kleine Erwachsene?
by Haarmann, Axel and Buttmann, Mathias
DNP - Der Neurologe & Psychiater, ISSN 1616-2455, 06/2019, Volume 20, Issue 3, pp. 27 - 28
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10. Full Text Neue PML-Risikofaktoren unter Natalizumab
by Buttmann, Mathias
DNP - Der Neurologe und Psychiater, ISSN 1616-2455, 9/2015, Volume 16, Issue 9, pp. 22 - 24
Ein JC-Virus-Antikörperindex über 1,5 zeigt bei nicht immunsuppressiv Vorbehandelten wahrscheinlich ein deutlich erhöhtes PML-Risiko unter Natalizumab an.... 
Psychotherapy | Neurology | Medicine & Public Health | Psychiatry | Psychopharmacology
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11. Full Text Neue Diagnosekriterien der Neuromyelitis-optica-Spektrumerkrankungen
by Buttmann, Mathias
DNP - Der Neurologe und Psychiater, ISSN 1616-2455, 9/2015, Volume 16, Issue 9, pp. 26 - 27
Neue internationale Konsensuskriterien lösen die revidierten Wingerchuk-Kriterien von 2006 ab. Man spricht ab jetzt nur noch von... 
Psychotherapy | Neurology | Medicine & Public Health | Psychiatry | Psychopharmacology
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12. Full Text Wirksamkeit der Grippeimpfung wird durch Immuntherapien der MS teilweise abgeschwächt
by Buttmann, Mathias
DNP - Der Neurologe und Psychiater, ISSN 1616-2455, 9/2015, Volume 16, Issue 9, pp. 20 - 22
Eine neue placebokontrollierte Studie weist nach, dass die Wirkung der Grippeschutzimpfung unter Fingolimod beeinträchtigt ist. Einige weitere... 
Neurology | Medicine & Public Health | Psychopharmacology | Psychotherapy | Psychiatry
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13. Full Text Wirksamkeit der Grippeimpfung wird durch Immuntherapien der MS teilweise abgeschwächt
by Buttmann, Mathias
DNP - Der Neurologe und Psychiater, ISSN 1616-2455, 09/2015, Volume 16, Issue 9, pp. 20 - 22
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14. Full Text Neue Studien zu Multipler Sklerose und Neuromyelitis optica
by Buttmann, Mathias
DNP - Der Neurologe und Psychiater, ISSN 1616-2455, 09/2015, Volume 16, Issue 9, pp. 18 - 19
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15. Full Text IL-6-Rezeptorblockade könnte therapeutisch anhaltend wirken
by Buttmann, Mathias
InFo Neurologie & Psychiatrie, ISSN 1437-062X, 09/2015, Volume 17, Issue 9, pp. 20 - 20
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16. Full Text Quadrivalente HPV-Impfung erhöht nicht das MS-Risiko
by Buttmann, Mathias
pädiatrie: Kinder- und Jugendmedizin hautnah, ISSN 1867-2132, 6/2015, Volume 27, Issue 3, pp. 17 - 17
Eine Kohortenstudie hat keine Assoziation zwischen der quadrivalenten HPV-Vakzinierung und dem Auftreten demyelinisierender Erkrankungen des zentralen... 
Medicine & Public Health | General Practice / Family Medicine | Pediatrics
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17. Full Text Investigation of the KIR4.1 potassium channel as a putative antigen in patients with multiple sclerosis: a comparative study
by Brickshawana, Adipong, PhD and Hinson, Shannon R, PhD and Romero, Michael F, Prof and Lucchinetti, Claudia F, Prof and Guo, Yong, MD and Buttmann, Mathias, MD and McKeon, Andrew, MD and Pittock, Sean J, Prof and Chang, Min-Hwang, PhD and Chen, An-Ping, PhD and Kryzer, Thomas J, AS and Fryer, James P, MS and Jenkins, Sarah M, MS and Cabre, Philippe, Prof and Lennon, Vanda A, Prof
Lancet Neurology, The, ISSN 1474-4422, 2014, Volume 13, Issue 8, pp. 795 - 806
Summary Background Antibodies have been implicated in the pathogenicity of multiple sclerosis by findings of immunoglobulins in patients' CSF and often IgG and... 
Neurology | ANTIBODIES | NEUROMYELITIS-OPTICA | AUTOIMMUNITY | ENCEPHALITIS | DISEASE | AQUAPORIN-4 | DISORDERS | ENVIRONMENTAL RISK-FACTORS | SPECTRUM | LESIONS | CLINICAL NEUROLOGY | Multiple Sclerosis - diagnosis | Immunoglobulin G - blood | Multiple Sclerosis - blood | Potassium Channels, Inwardly Rectifying - cerebrospinal fluid | Humans | Middle Aged | Male | Young Adult | Immunoglobulin G - biosynthesis | Immunoglobulin G - cerebrospinal fluid | Aged, 80 and over | Adult | Female | Child | Multiple Sclerosis - cerebrospinal fluid | Autoantigens - blood | Autoantigens - cerebrospinal fluid | Biomarkers - blood | Potassium Channels, Inwardly Rectifying - blood | Autoantigens - immunology | Adolescent | Aged | Biomarkers - cerebrospinal fluid | Population Surveillance | Protein Binding - physiology | Hypertension | Antigens | Medical research | Care and treatment | Multiple sclerosis | Immunoglobulin G | Medicine, Experimental | Potassium channels | Comparative analysis | Patents | Disease | Peptides | Royalties | Pathogenesis | Cloning | Aquaporins | RNA polymerase | Patients | Proteins | Studies | Brain research | Inventors | Biopsy | Consent | Population | Charitable foundations | Immune system | Index Medicus
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18. Full Text Quadrivalente HPV-Impfung erhöht nicht das Risiko einer Multiplen Sklerose
by Buttmann, Mathias
InFo Neurologie & Psychiatrie, ISSN 1437-062X, 03/2015, Volume 17, Issue 3, pp. 18 - 18
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19. Full Text Mindestens so wirksam wie Beta-Interferone, aber mehr Nebenwirkungen?
by Buttmann, Mathias
InFo Neurologie & Psychiatrie, ISSN 1437-062X, 2/2015, Volume 17, Issue 2, pp. 20 - 20
Medicine & Public Health | Neurology | Psychiatry
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20. Full Text Fumaric Acid Esters Do Not Reduce Inflammatory NF-[kappa]B/p65 Nuclear Translocation, ICAM-1 Expression and T-Cell Adhesiveness of Human Brain Microvascular Endothelial Cells
by Axel Haarmann and Mathias Nehen and Annika Deiß and Mathias Buttmann
International Journal of Molecular Sciences, ISSN 1661-6596, 08/2015, Volume 16, Issue 8, p. 19086
  Dimethyl fumarate (DMF) is approved for disease-modifying treatment of patients with relapsing-remitting multiple sclerosis. Animal experiments suggested... 
Blood-brain barrier | Acids | Inflammation | Gene expression | Cell adhesion & migration
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