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1. Full Text Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years
by Powell, J. T and Sweeting, M. J and Ulug, P and Blankensteijn, J. D and Lederle, F. A and Becquemin, J.-P and Greenhalgh, R. M and EVAR-1 and OVER and ACE Trialists and DREAM and EVAR-1, DREAM, OVER and ACE Trialists and the EVAR-1, DREAM, OVER and ACE Trialists
British journal of surgery, ISSN 0007-1323, 2017, Volume 104, Issue 3, pp. 166 - 178
Life Sciences & Biomedicine | Surgery | Science & Technology | Vascular Grafting - methods | Reoperation | Aortic Aneurysm, Abdominal - mortality | Aortic Aneurysm, Abdominal - surgery | Humans | Middle Aged | Endovascular Procedures | Male | Treatment Outcome | Models, Statistical | Randomized Controlled Trials as Topic | Multicenter Studies as Topic | Aged, 80 and over | Female | Aged | Elective Surgical Procedures - methods | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Systematic Review | Systematic Reviews
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2. Full Text A new highly penetrant form of obesity due to deletions on chromosome 16p11.2
by Walters, R G and Jacquemont, S and Valsesia, A and de Smith, A J and Martinet, D and Andersson, J and Falchi, M and Chen, F and Anieux, J and Lobbens, S and Delobel, B and Stutzmann, F and El-Sayed Moustafa, J S and Chèvre, J-C and Lecoeur, C and Vatin, V and Bouquillon, S and Buxton, J L and Boute, O and Holder-Espinasse, M and Cuisset, J-M and Lemaitre, M-P and Ambresin, A-E and Brioschi, A and Gaillard, M and Giusti, V and Fellmann, F and Ferrarini, A and Hadjikhani, N and Campion, D and Guilmatre, A and Goldenberg, A and Calmels, N and Mandel, J-L and Le Caignec, C and David, A and Isidor, B and Cordier, M-P and Dupuis-Girod, S and Labalme, A and Sanlaville, D and Béri-Dexheimer, M and Jonveaux, P and Leheup, B and Ounap, K and Bochukova, E G and Henning, E and Keogh, J and Ellis, R J and Macdermot, K D and van Haelst, M M and Vincent-Delorme, C and Plessis, G and Touraine, R and Philippe, A and Malan, V and Mathieu-mard, M and Chiesa, J and Blaumeiser, B and Kooy, R F and Caiazzo, R and Pigeyre, M and Balkau, B and Sladek, R and Bergmann, S and Mooser, V and Waterworth, D and Reymond, A and Vollenweider, P and Waeber, G and Kurg, A and Palta, P and Esko, T and Metspalu, A and Nelis, M and Elliott, P and Hartikainen, A-L and McCarthy, M I and Peltonen, L and Carlsson, L and Jacobson, P and Sjöström, L and Huang, N and Hurles, M E and O'Rahilly, S and Farooqi, I S and Männik, K and Jarvelin, M-R and Pattou, F and Meyre, D and Walley, A J and Coin, L J M and Blakemore, A I F and Froguel, P and Beckmann, J S and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Nature (London), ISSN 0028-0836, 02/2010, Volume 463, Issue 7281, pp. 671 - 5
Body Mass Index | Chromosome Deletion | Genome-Wide Association Study | Reproducibility of Results | Mutation/genetics | Europe | Humans | Chromosomes, Human, Pair 16/genetics | Male | Penetrance | Sex Characteristics | Case-Control Studies | Young Adult | Inheritance Patterns/genetics | Adolescent | Age of Onset | Aging | Obesity/complications | Adult | Female | Heterozygote | Child | Cognition Disorders/complications | Cohort Studies | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Obesity | Biological and medical sciences | Metabolic diseases | Medical sciences | Obesity - genetics | Inheritance Patterns - genetics | Chromosomes, Human, Pair 16 - genetics | Obesity - complications | Obesity - physiopathology | Cognition Disorders - genetics | Mutation - genetics | Cognition Disorders - complications | Studies | Autism | Genotype & phenotype | Penetrants | Deletion | Genetics | Nuclear power generation | Nucleotides | Loci | Public health | Index Medicus | Inheritance Patterns | Medicinsk genetik | Medical Genetics | genetics | Chromosomes | Human | complications | physiopathology | Cognition Disorders | Mutation | Pair 16
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3. Full Text Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial
by Bath, Philip M and Woodhouse, Lisa J and Appleton, Jason P and Beridze, Maia and Christensen, Hanne and Dineen, Robert A and Duley, Lelia and England, Timothy J and Flaherty, Katie and Havard, Diane and Heptinstall, Stan and James, Marilyn and Krishnan, Kailash and Markus, Hugh S and Montgomery, Alan A and Pocock, Stuart J and Randall, Marc and Ranta, Annemarei and Robinson, Thompson G and Scutt, Polly and Venables, Graham S and Sprigg, Nikola and Christensen, L M and Bentsen, L and Krarup Hansen, C and Thomsen, T T and Kruuse, C and Jensen, H H and Hansen, S S and Petrovic, V and Beridze, N and Kakabadze, N and Kherkheulidze, T and Kakabadze, D and Toidze, I and Lobjanidze, N and Akiashvili, N and Tevdoradze, A and Khizanishvili, N and Tsanava, T and Taylor, R and Iniesta, I and Kok, J and Duignan, J and Funnell, M and Cariga, P and Rodriguez, M and Watson, I J and Tennant, S and Macleod, M and Furnace, J and Gow, H and Irvine, J and Joyson, A and Nelson, S and Taylor, V and Smith, M and Bellfield, R and Hairsine, B and Davies, R and Dodd, A and Corrigan, J and Doherty, M and Ahmed, A and Denniss, C and Johnson-Holland, S and Kay, K A and Palau, R Icart and Auld, G and Daboo, P and Erande, R and Grimwood, G and Hove, D and Howaniec, L and Redjep, O and Rangasamay, R and Butt, G and Sandler, D and Reddan, J and Stafford, S and McIlmoyle, J and Maguire, S and Murphy, P and Chambers, J and Guthrie, L and Osborn, M and Steele, A and Burn, M and Benford, A and Misra, A and Hilton, D and O'Brien, E and Amis, E and Finlay, S and Mitchell, J and Geraghty, O and Harvey, K and Hazel, B and Mashate, S and Wilding, P and ... and TARDIS Investigators
The Lancet (British edition), ISSN 0140-6736, 03/2018, Volume 391, Issue 10123, pp. 850 - 859
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Recurrence | Prospective Studies | Ticlopidine - pharmacology | Humans | Middle Aged | Male | Ischemic Attack, Transient - chemically induced | Aspirin - administration & dosage | Aspirin - adverse effects | Dipyridamole - pharmacology | Thrombolytic Therapy - methods | Ticlopidine - adverse effects | Dipyridamole - adverse effects | Ticlopidine - administration & dosage | Female | Stroke - epidemiology | Aspirin - pharmacology | Drug Therapy, Combination | Ischemia - pathology | Acute Disease | Risk Assessment | Treatment Outcome | Stroke - drug therapy | Ticlopidine - analogs & derivatives | Ischemic Attack, Transient - epidemiology | Stroke - etiology | Ischemia - drug therapy | Brain Ischemia - drug therapy | Platelet Aggregation Inhibitors | Denmark - epidemiology | Clopidogrel | Research Design - standards | Aged | Dipyridamole - administration & dosage | Hemorrhage - chemically induced | United Kingdom - epidemiology | Georgia - epidemiology | New Zealand - epidemiology | Prevention | Heart | Aspirin | Stroke | Medical imaging | Ischemia | Nitric oxide | Technology assessment | Dipyridamole | Patients | Evidence-based medicine | Index Medicus | Abridged Index Medicus
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4. Full Text Identification of seven loci affecting mean telomere length and their association with disease
by Codd, Veryan and Nelson, Christopher P and Albrecht, Eva and Mangino, Massimo and Deelen, Joris and Buxton, Jessica L and Hottenga, Jouke Jan and Fischer, Krista and Esko, Tonu and Surakka, Ida and Broer, Linda and Nyholt, Dale R and Mateo Leach, Irene and Salo, Perttu and Hagg, Sara and Matthews, Mary K and Palmen, Jutta and Norata, Giuseppe D and O'Reilly, Paul F and Saleheen, Danish and Amin, Najaf and Balmforth, Anthony J and Beekman, Marian and de Boer, Rudolf A and Bohringer, Stefan and Braund, Peter S and Burton, Paul R and de Craen, Anton J. M and Denniff, Matthew and Dong, Yanbin and Douroudis, Konstantinos and Dubinina, Elena and Eriksson, Johan G and Garlaschelli, Katia and Guo, Dehuang and Hartikainen, Anna-Liisa and Henders, Anjali K and Houwing-Duistermaat, Jeanine J and Kananen, Laura and Karssen, Lennart C and Kettunen, Johannes and Klopp, Norman and Lagou, Vasiliki and van Leeuwen, Elisabeth M and Madden, Pamela A and Maegi, Reedik and Verweij, Niek and van Veldhuisen, Dirk J and van Gilst, Wiek H and van der Harst, Pim and CARDIoGRAM Consortium and CARDIoGRAM consortium
Nature genetics, ISSN 1061-4036, 04/2013, Volume 45, Issue 4, pp. 422 - 427
VARIANTS | SUSCEPTIBILITY | CARDIOVASCULAR-DISEASE | ATHEROSCLEROSIS | RISK | DYSFUNCTION | STRESS | CANCER | CORONARY-ARTERY-DISEASE | FIBROBLASTS | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Disease - genetics | Humans | Risk Factors | Genetic Loci - genetics | Male | Case-Control Studies | Telomerase - genetics | Female | Biomarkers, Tumor - genetics | Leukocytes - metabolism | Telomere - genetics | DNA polymerases | Physiological aspects | Telomeres | Genetic aspects | Research | Aging | Genetics | Gene therapy | Chromosomes | Deoxyribonucleic acid--DNA | Index Medicus | Medicin och hälsovetenskap
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5. Full Text Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a randomised controlled trial
by FOxTROT Collaborative Group and Foxtrot Collaborative Grp
The lancet oncology, ISSN 1470-2045, 2012, Volume 13, Issue 11, pp. 1152 - 1160
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Colonic Neoplasms - drug therapy | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Combined Modality Therapy | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Fluorouracil - adverse effects | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Colonic Neoplasms - pathology | Aged, 80 and over | Adult | Female | Neoadjuvant Therapy | Aged | Rectal Neoplasms - pathology | Neoplasm Staging | Rectal Neoplasms - drug therapy | Organoplatinum Compounds - adverse effects | Preoperative Period | Neoadjuvant therapy | Chemotherapy | Colon cancer | Cancer | Index Medicus
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6. Full Text A Comparison of Antiarrhythmic-Drug Therapy with Implantable Defibrillators in Patients Resuscitated from Near-Fatal Ventricular Arrhythmias
by McAnulty, J and Halperin, B and Kron, J and Larsen, G and Rait, M and Swenson, R and Floreck, R and Marchant, C and Hamlin, M and Heywood, G and Friedman, P and Stevenson, W and Swat, M and Ganz, L and Sweeney, M and Shea, J and Steinberg, J and Ehlert, F and Zelenkofstke, S and Menchavez-Tan, E and De Stefano, M and Brown, G and Karagounis, L and Crandall, B and Osborn, J and Rawling, D and Summers, K and Jacobsen, M and Herre, J and Bernsteim, R and Klevan, L and Cannom, D and Bhandari, A and Lerman, R and Firth, B and Klein, R and Freedman, R and Marks, M and Delahunty, M and Spratt, C and Marinchak, R and Rials, S and Kowey, P and Fillart, R and Hernandez, M and Scher, D and Zukerman, L and Farrell, S and Cross, J and Shewchjik, J and Epstein, A and Cooper, R and Dailey, R and Dailey, S and Kay, G and Plumb, V and Bubien, R and Knotts-Dolson, S and McKenna, P and Tidwell, C and Kim, S and Fisher, J and Ferrick, K and Gross, J and Ben-Zur, U and Durkin, J and Ferrick, A and Beckman, K and McClelland, J and Gonzalez, M and Widman, L and Lane, R and Deaton, T and Foster, J and Straughan, G and Wade, L and Brodsky, M and Allen, B and Ehrlich, S and Wolff, L and Macari-Hinson, M and Coromilas, J and Bigger T, Jr and Livelli F, Jr and Reiffel, J and Hickey, K and Akiyama, T and Daubert, J and Kim, C and Switzer, D and Pande, P and Flynn, D and Keller, M and Ocampo, C and Wahl, K and Vogt, J and Kutalek, S and Hessen, S and Movsowitz, C and The Antiarrhythmics versus Implantable Defibrillators (AVID) Investigators and Antiarrhythmics versus Implantable Defibrillators (AVID) Investigators
The New England journal of medicine, ISSN 0028-4793, 11/1997, Volume 337, Issue 22, pp. 1576 - 1584
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | Intensive care medicine | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care | Tachycardia, Ventricular - therapy | Ventricular Fibrillation - drug therapy | Tachycardia, Ventricular - drug therapy | Humans | Middle Aged | Ventricular Fibrillation - mortality | Male | Anti-Arrhythmia Agents - therapeutic use | Sotalol - therapeutic use | Tachycardia, Ventricular - mortality | Amiodarone - therapeutic use | Defibrillators, Implantable | Statistics, Nonparametric | Survival Analysis | Female | Aged | Ventricular Fibrillation - therapy | Resuscitation | Prevention | Evaluation | Defibrillators | Arrhythmia | Anti-arrhythmia drugs | Comparative studies | Medical research | Cardiac arrhythmia | Drug therapy | Index Medicus | Abridged Index Medicus
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