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Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 1, pp. 42 - 51
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, p. e36116
Cleft Lip and Palate Transmembrane Protein 1-Like (CLPTM1L), resides in a region of chromosome 5 for which copy number gain has been found to be the most... 
APOPTOSIS | VARIANTS | ASSOCIATE | SUSCEPTIBILITY | BIOLOGY | INHIBITOR | BCL-X(L) | EXPRESSION | CARCINOMA | CELL-DEATH | FAMILY | Lung Neoplasms - genetics | Genetic Predisposition to Disease | Mutagens - toxicity | Adenocarcinoma of Lung | Genetic Association Studies | Apoptosis - drug effects | Membrane Proteins - genetics | Humans | Risk Factors | Genetic Loci - genetics | Apoptosis - genetics | Neoplasm Proteins - metabolism | Drug Resistance, Neoplasm - genetics | Cell Line, Tumor | DNA Damage - genetics | Adenocarcinoma - genetics | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | bcl-X Protein - metabolism | Chromosomes, Human, Pair 5 - genetics | Drug Resistance, Neoplasm - drug effects | Chemotherapy | Oncology, Experimental | Genomes | Genetic aspects | Research | Lung cancer, Non-small cell | Health aspects | Risk factors | Cancer | Camptothecin | Biotechnology | Copy number | Genes | Lung cancer | Genotoxicity | Cytotoxicity | Kinases | Tissues | Accumulation | Ovarian cancer | Proteins | Toxicology | Bcl-x protein | Tumorigenesis | Killing | Tumor cells | Health risks | Non-small cell lung carcinoma | Pharmacology | Chromosome 5 | Tumor cell lines | Loci | Cisplatin | Cleft lip/palate | Biomarkers | Cervical cancer | Smoking | Apoptosis | Tumors
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0152584
Small cell lung cancer (SCLC) is an aggressive malignancy with limited treatment options. We previously found that PARP is overexpressed in SCLC and that... 
BREAST-CANCER | POLY(ADP-RIBOSE) POLYMERASE | IN-VITRO | MULTIDISCIPLINARY SCIENCES | RESISTANCE | THERAPEUTIC TARGETS | DNA-REPAIR | TUMORS | CARCINOMA | DRUG-DRUG INTERACTIONS | PI3K INHIBITOR | Lung Neoplasms - drug therapy | AMP-Activated Protein Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Neoplasm Proteins - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - metabolism | Neoplasm Proteins - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Indoles - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | AMP-Activated Protein Kinases - antagonists & inhibitors | Morpholines - pharmacology | Piperazines - pharmacology | Xenograft Model Antitumor Assays | Phthalazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Small Cell Lung Carcinoma - pathology | Animals | Mice, Nude | Aminopyridines - pharmacology | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Poly (ADP-Ribose) Polymerase-1 | Physiological aspects | Lung cancer, Small cell | Development and progression | Genetic aspects | Cellular signal transduction | Research | TOR protein | Drugs | Cell culture | Biotechnology | Animal models | Lung cancer | AKT protein | Oncology | Biology | Activation | Malignancy | Kinases | Cancer therapies | DNA repair | Ovarian cancer | Proteins | LKB1 protein | Signal transduction | Rodents | Bioindicators | Inhibition | Bioinformatics | Pharmaceutical sciences | Deoxyribonucleic acid--DNA | Medical research | Small cell lung carcinoma | Poly(ADP-ribose) polymerase | Breast cancer | Bioavailability | 1-Phosphatidylinositol 3-kinase | Studies | Signaling | Chemotherapy | Gene amplification | Protein arrays | Inhibitors | Biopsy | Cell lines | Biomarkers | In vivo methods and tests | ATP | Tumors | Cancer | Deoxyribonucleic acid | DNA
Journal Article
Nature Communications, ISSN 2041-1723, 10/2014, Volume 5, Issue 1, p. 5241
Journal Article
Cancer Discovery, ISSN 2159-8274, 10/2019, Volume 9, Issue 10, pp. 1340 - 1342
Journal Article
by Campbell, Joshua D and Yau, Christina and Bowlby, Reanne and Liu, Jia and Liu, Yuexin and Liu, Wenbin and Liu, Xiuping and Brennan, Kevin and Fan, Huihui and Fan, Cheng and Taylor, Alison M and Taylor, Barry S and Wang, Jioajiao and Wang, Min and Wang, Jing and Wang, Timothy and Wang, Zhining and Wang, Chen and Wang, Linghua and Walter, Vonn and Akbani, Rehan and Byers, Lauren Averett and Creighton, Chad J and Coarfa, Cristian and Shih, Juliann and Cherniack, Andrew D and Gevaert, Olivier and Prunello, Marcos and Shen, Ronglei and Shen, Hui and Anur, Pavana and Chen, Jianhong and Chen, Zhong and Chen, Ting-Wen and Chen, Amy and Chen, Chu and Cheng, Feixiong and Cheng, Hui and Hayes, D. Neil and Bullman, Susan and Pedamallu, Chandra Sekhar and Ojesina, Akinyemi I and Sadeghi, Sara and Mungall, Karen L and Mungall, Andrew J and Mungall, Karen and Robertson, A. Gordon and Benz, Christopher and Schultz, Andre and Schultz, Nikolaus and Kanchi, Rupa S and Gay, Carl M and Hegde, Apurva M and Hegde, Apurva and Diao, Lixia and Ma, Deqin and Ma, Wencai and Ma, Yussanne and Sumazin, Pavel and Chiu, Hua-Sheng and Gunaratne, Preethi and Donehower, Larry and Donehower, Lawrence A and Rader, Janet S and Zuna, Rosemary and Al-Ahmadie, Hikmat and Lazar, Alexander J and Flores, Elsa R and Tsai, Kenneth Y and Zhou, Jane H and Zhou, Wanding and Rustgi, Anil K and Drill, Esther and Wong, Tina and Wong, Christopher K and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Ian and Yang, Liming and Yang, Ju Dong and Yang, Hannah and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Hailei and Zhang, Lizhi and Zhang, Hongzheng and Zhang, Wei and Zhang, Hongxin and Zhang, Jiexin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 194 - 212.e6
Journal Article