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Cancer, ISSN 0008-543X, 03/2015, Volume 121, Issue 5, pp. 664 - 672
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 01/2017, Volume 12, Issue 1, pp. S1088 - S1089
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 01/2017, Volume 12, Issue 1, pp. S1088 - S1089
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 4392 - 4392
Journal Article
Cancer Informatics, ISSN 1176-9351, 05/2016, Volume 2016, Issue 15, pp. 81 - 89
Journal Article
Cancer discovery, ISSN 2159-8274, 9/2014, Volume 4, Issue 9, pp. 991 - 994
10 years after the approval of erlotinib, EGFR inhibitor resistance remains a major clinical challenge. The translation of afatinib plus cetuximab into the... 
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 08/2016, Volume 11, Issue 8, pp. 1357 - 1362
The Axl receptor tyrosine kinase belongs to the TAM (Tyro3, Axl, Mer) family of proteins and is upregulated in multiple types of cancers, including non-small... 
Index Medicus
Journal Article
by Lawrence, Michael S and Sougnez, Carrie and Lichtenstein, Lee and Cibulskis, Kristian and Lander, Eric and Gabriel, Stacey B and Getz, Gad and Ally, Adrian and Balasundaram, Miruna and Birol, Inanc and Bowlby, Reanne and Brooks, Denise and Butterfield, Yaron S. N and Carlsen, Rebecca and Cheng, Dean and Chu, Andy and Dhalla, Noreen and Guin, Ranabir and Holt, Robert A and Jones, Steven J.M and Lee, Darlene and Li, Haiyan I and Marra, Marco A and Mayo, Michael and Moore, Richard A and Mungall, Andrew J and Robertson, A. Gordon and Schein, Jacqueline E and Sipahimalani, Payal and Tam, Angela and Thiessen, Nina and Wong, Tina and Protopopov, Alexei and Santoso, Netty and Lee, Semin and Parfenov, Michael and Zhang, Jianhua and Mahadeshwar, Harshad S and Tang, Jiabin and Ren, Xiaojia and Seth, Sahil and Haseley, Psalm and Zeng, Dong and Yang, Lixing and Xu, Andrew W and Song, Xingzhi and Pantazi, Angeliki and Bristow, Christopher A and Hadjipanayis, Angela and Seidman, Jonathan and Chin, Lynda and Park, Peter J and Kucherlapati, Raju and Akbani, Rehan and Casasent, Tod and Liu, Wenbin and Lu, Yiling and Mills, Gordon and Motter, Thomas and Weinstein, John and Diao, Lixia and Wang, Jing and Hong Fan, You and Liu, Jinze and Wang, Kai and Auman, J. Todd and Balu, Saianand and Bodenheimer, Thomas and Buda, Elizabeth and Hayes, D. Neil and Hoadley, Katherine A and Hoyle, Alan P and Jefferys, Stuart R and Jones, Corbin D and Kimes, Patrick K and Liu, Yufeng and Marron, J.S and Meng, Shaowu and Mieczkowski, Piotr A and Mose, Lisle E and Parker, Joel S and Perou, Charles M and Prins, Jan F and Roach, Jeffrey and Shi, Yan and Simons, Janae V and Singh, Darshan and Soloway, Matthew G and Tan, Donghui and Veluvolu, Umadevi and Walter, Vonn and Waring, Scot and Wilkerson, Matthew D and Wu, Junyuan and Zhao, Ni and Cherniack, Andrew D and Hammerman, Peter S and Tward, Aaron D and Pedamallu, Chandra Sekhar and Saksena, Gordon and ... and Canc Genome Atlas Network and Cancer Genome Atlas Network and The Cancer Genome Atlas Network
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7536, pp. 576 - 582
Journal Article
by Collisson, Eric A and Campbell, Joshua D and Brooks, Angela N and Berger, Alice H and Lee, William and Chmielecki, Juliann and Beer, David G and Cope, Leslie and Creighton, Chad J and Danilova, Ludmila and Ding, Li and Getz, Gad and Hammerman, Peter S and Hayes, D. Neil and Hernandez, Bryan and Herman, James G and Heymach, John V and Jurisica, Igor and Kucherlapati, Raju and Kwiatkowski, David and Ladanyi, Marc and Robertson, Gordon and Schultz, Nikolaus and Shen, Ronglai and Sinha, Rileen and Sougnez, Carrie and Tsao, Ming-Sound and Travis, William D and Weinstein, John N and Wigle, Dennis A and Wilkerson, Matthew D and Chu, Andy and Cherniack, Andrew D and Hadjipanayis, Angela and Rosenberg, Mara and Weisenberger, Daniel J and Laird, Peter W and Radenbaugh, Amie and Ma, Singer and Stuart, Joshua M and Byers, Lauren Averett and Baylin, Stephen B and Govindan, Ramaswamy and Meyerson, Matthew and Gabriel, Stacey B and Cibulskis, Kristian and Kim, Jaegil and Stewart, Chip and Lichtenstein, Lee and Lander, Eric S and Lawrence, Michael S and Getz, E and Fulton, Robert and Fulton, Lucinda L and McLellan, Michael D and Wilson, Richard K and Ye, Kai and Fronick, Catrina C and Maher, Christopher A and Miller, Christopher A and Wendl, Michael C and Cabanski, Christopher and Mardis, Elaine and Wheeler, David and Balasundaram, Miruna and Butterfield, Yaron S. N and Carlsen, Rebecca and Chuah, Eric and Dhalla, Noreen and Guin, Ranabir and Hirst, Carrie and Lee, Darlene and Li, Haiyan I and Mayo, Michael and Moore, Richard A and Mungall, Andrew J and Schein, Jacqueline E and Sipahimalani, Payal and Tam, Angela and Varhol, Richard and Robertson, A. Gordon and Wye, Natasja and Thiessen, Nina and Holt, Robert A and Jones, Steven J.M and Marra, Marco A and Imielinski, Marcin and Onofrio, Robert C and Hodis, Eran and Zack, Travis and Helman, Elena and Pedamallu, Chandra Sekhar and Mesirov, Jill and Saksena, Gordon and Schumacher, Steven E and Carter, Scott L and Garraway, Levi and Beroukhim, Rameen and Lee, Semin and Mahadeshwar, Harshad S and ...
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7511, pp. 543 - 550
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2013, Volume 19, Issue 1, pp. 279 - 290
Journal Article
Cancer Discovery, ISSN 2159-8274, 2017, Volume 7, Issue 6, pp. 620 - 629
Talazoparib inhibits PARP catalytic activity, trapping PARP1 on damaged DNA and causing cell death in BRCA1/2-mutated cells. We evaluated talazoparib therapy... 
CELL LUNG-CANCER | POLY(ADP-RIBOSE) POLYMERASE | OLAPARIB | EVALUATE | ONCOLOGY | PANCREATIC-CANCER | PROSTATE-CANCER | CLINICAL-TRIALS | DNA-REPAIR | TUMORS | BMN 673 | Index Medicus
Journal Article
Cancer discovery, ISSN 2159-8274, 01/2019, Volume 9, Issue 1, pp. 16 - 18
Mutations in STK11 (LKB1) are a major cause of primary resistance to immunotherapy in non-small cell lung cancer. Kitajima and colleagues dissect the... 
ONCOLOGY
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 14, pp. 3870 - 3884
Effective targeted therapies for small-cell lung cancer (SCLC), the most aggressive form of lung cancer, remain urgently needed. Here we report evidence of... 
GENE | SIGNATURES | ONCOLOGY | BIOLOGY | RESISTANCE | PARP | MODEL | MUTATIONS | IDENTIFICATION | Piperazines - administration & dosage | Lung Neoplasms - drug therapy | Humans | Pyrazines - administration & dosage | Small Cell Lung Carcinoma - enzymology | Lung Neoplasms - pathology | Small Cell Lung Carcinoma - drug therapy | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Cisplatin - administration & dosage | Gene Knockdown Techniques | Biomarkers, Tumor - metabolism | Female | Pyrazoles - pharmacology | Lung Neoplasms - genetics | Phthalazines - administration & dosage | Checkpoint Kinase 1 - antagonists & inhibitors | Small Cell Lung Carcinoma - genetics | Cisplatin - pharmacology | Piperazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Drug Synergism | Checkpoint Kinase 1 - metabolism | Phthalazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Pyrazoles - administration & dosage | Small Cell Lung Carcinoma - pathology | Animals | Mice, Nude | Cell Line, Tumor | Mice | Pyrazines - pharmacology | Checkpoint Kinase 1 - genetics | Medical research | Cell culture | Effectiveness | Small cell lung carcinoma | RNA-mediated interference | CHK1 protein | Lung | Lung cancer | Clinical trials | Poly(ADP-ribose) polymerase | Pharmacology | Myc protein | Kinases | Cisplatin | Anticancer properties | Amplification | Inhibitors | Platinum | Biomarkers | Antitumor activity | Bioindicators | Inhibition | Cancer | Index Medicus
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