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1. Full Text Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
by Armitage, Jane and Baigent, Colin and Barnes, Elizabeth and Betteridge, D John and Blackwell, Lisa and Blazing, Michael and Bowman, Louise and Braunwald, Eugene and Byington, Robert and Cannon, Christopher and Clearfield, Michael and Colhoun, Helen and Collins, Rory and Dahlöf, Björn and Davies, Kelly and Davis, Barry and de Lemos, James and Downs, John R and Durrington, Paul and Emberson, Jonathan and Fellström, Bengt and Flather, Marcus and Ford, Ian and Franzosi, Maria Grazia and Fulcher, Jordan and Fuller, John and Furberg, Curt and Gordon, David and Goto, Shinya and Gotto, Antonio and Halls, Heather and Harper, Charlie and Hawkins, C Morton and Herrington, Will and Hitman, Graham and Holdaas, Hallvard and Holland, Lisa and Jardine, Alan and Jukema, J Wouter and Kastelein, John and Kean, Sharon and Keech, Anthony and Kirby, Adrienne and Kjekshus, John and Knatterud (deceased), Genell and Knopp (deceased), Robert and Koenig, Wolfgang and Koren, Michael and Krane, Vera and Landray, Martin J and LaRosa, John and Lonn, Eva and MacFarlane, Peter and MacMahon, Stephen and Maggioni, Aldo and Marchioli, Roberto and Marschner, Ian and Mihaylova, Borislava and Moyé, Lemuel and Murphy, Sabina and Nakamura, Haruo and Neil, Andrew and Newman, Connie and O'Connell, Rachel and Packard, Chris and Parish, Sarah and Pedersen, Terje and Peto, Richard and Pfeffer, Marc and Poulter, Neil and Preiss, David and Reith, Christina and Ridker, Paul and Robertson, Michele and Sacks, Frank and Sattar, Naveed and Schmieder, Roland and Serruys, Patrick and Sever, Peter and Shaw, John and Shear, Charles and Simes, John and Sleight, Peter and Spata, Enti and Tavazzi, Luigi and Tobert, Jonathan and Tognoni, Gianni and Tonkin, Andrew and Trompet, Stella and Varigos, John and Wanner, Christoph and Wedel, Hans and White, Harvey and Wikstrand, John and Wilhelmsen, Lars and Wilson, Kate and Young, Robin and Yusuf, Salim and Zannad, Faiez and Cholesterol Treatment Trialists' Collaboration and Cholesterol Treatment Trialists Co
The Lancet (British edition), ISSN 0140-6736, 02/2019, Volume 393, Issue 10170, pp. 407 - 415
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Aged | Age Factors | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Randomized Controlled Trials as Topic | Blood circulation disorders | Coronary artery bypass | Analysis | Cardiac patients | Low density lipoproteins | Trans fatty acids | Statins | Cardiovascular agents | Heart | Lipoproteins (low density) | Clinical trials | Risk | Evidence-based medicine | Incidence | Heterogeneity | Randomization | Reduction | Vascular diseases | Older people | Patient safety | Safety | Heart diseases | Age | Medical research | Stroke | Data analysis | Statistical analysis | Mortality | Patients | Disease control | Cholesterol | Meta-analysis | Renal failure | Dialysis | Health risk assessment | Cancer | Index Medicus | Abridged Index Medicus
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2. Full Text Epidemiologic relationships between A1C and all-cause mortality during a median 3.4-year follow-up of glycemic treatment in the ACCORD trial
by Riddle, Matthew C and Ambrosius, Walter T and Brillon, David J and Buse, John B and Byington, Robert P and Cohen, Robert M and Goff Jr, David C and Malozowski, Saul and Margolis, Karen L and Probstfield, Jeffrey L and Schnall, Adrian and Seaquist, Elizabeth R and Action Control Cardiovasc Risk Dia and Action to Control Cardiovascular Risk in Diabetes Investigators and for the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Investigators
Diabetes care, ISSN 0149-5992, 05/2010, Volume 33, Issue 5, pp. 983 - 990
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Public health. Hygiene-occupational medicine | Public health. Hygiene | Diabetes. Impaired glucose tolerance | Miscellaneous | Biological and medical sciences | Endocrinopathies | Metabolic diseases | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Hypoglycemic Agents - therapeutic use | Multivariate Analysis | Follow-Up Studies | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Risk Factors | Male | Hyperglycemia - drug therapy | Cause of Death | Diabetes Mellitus, Type 2 - mortality | Female | Aged | Hyperglycemia - mortality | Diabetes Mellitus, Type 2 - drug therapy | Type 2 diabetes | Clinical trials | Pharmaceutical industry | United States | Health aspects | Mortality | Blood pressure | Diabetes | Hypoglycemia | Drug dosages | Pharmaceuticals | Index Medicus | Original Research
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3. Pacemaker Implantation After Mitral Valve Surgery With Atrial Fibrillation Ablation
by DeRose, Joseph J and Mancini, Donna M and Chang, Helena L and Argenziano, Michael and Dagenais, François and Ailawadi, Gorav and Perrault, Louis P and Parides, Michael K and Taddei-Peters, Wendy C and Mack, Michael J and Glower, Donald D and Yerokun, Babatunde A and Atluri, Pavan and Mullen, John C and Puskas, John D and O'Sullivan, Karen and Sledz, Nancy M and Tremblay, Hugo and Moquete, Ellen and Ferket, Bart S and Moskowitz, Alan J and Iribarne, Alexander and Gelijns, Annetine C and O'Gara, Patrick T and Blackstone, Eugene H and Gillinov, A. Marc and Miller, Marissa A and Buxton, Dennis and Connolly, Amy and Geller, Nancy L and Gordon, David and Jeffries, Neal O and Lee, Albert and Moy, Claudia S and Gombos, Ilana Kogan and Ralph, Jennifer and Weisel, Richard and Gardner, Timothy J and Rose, Eric A and Ascheim, Deborah D and Bagiella, Emilia and Chang, Helena and Chase, Melissa and Dobrev, Edlira and Goldfarb, Seth and Gupta, Lopa and Kirkwood, Katherine and Levitan, Ron and Overbey, Jessica and Santos, Milerva and Weglinski, Michael and Williams, Paula and Wood, Carrie and Ye, Xia and Mack, Michael and Adame, Tracine and Settele, Natalie and Adams, Jenny and Ryan, William and Smith, Robert L and Grayburn, Paul and Chen, Frederick Y and Nohria, Anju and Cohn, Lawrence and Shekar, Prem and Aranki, Sary and Couper, Gregory and Davidson, Michael and Bolman, R. Morton and Burgess, Anne and Conboy, Debra and Blackwell, Ray and Kerzner, Roger and Banbury, Michael and Squire, Andrea M and Lytle, Bruce and Mihaljevic, Tomislav and Lackner, Pamela and Berroteran, Leoma and Dolney, Diana and Fleming, Suzanne and Palumbo, Roberta and Whitman, Christine and Sankovic, Kathy and Sweeney, Denise Kosty and Pattakos, Gregory and Williams, Mathew and Goldsmith, Lyn and Smith, Craig R and Naka, Yoshifumi and Stewart, Allan and Schwartz, Allan and Bell, Daniel and Van Patten, Danielle and Sreekanth, Sowmya and Smith, Peter K and Alexander, John H and Milano, Carmelo A and Mathew, Joseph P and Harrison, J. Kevin and ... and CTSN Investigators
Journal of the American College of Cardiology, ISSN 0735-1097, 05/2019, Volume 73, Issue 19, pp. 2427 - 2435
cardiac surgery | valvular heart disease | biatrial maze | pulmonary vein isolation | permanent pacemaker | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Atrial Fibrillation - therapy | Humans | Middle Aged | Risk Factors | Pulmonary Veins - innervation | Male | Mitral Valve - surgery | Heart Valve Diseases - surgery | Cardiac Pacing, Artificial | Atrial Fibrillation - surgery | Heart Atria - surgery | Catheter Ablation - methods | Heart Atria - innervation | Female | Aged | Cardiac Surgical Procedures - methods | Pulmonary Veins - surgery | Heart failure | Hypertension | Cardiac arrhythmia | Stroke | Mitral valve | Heart surgery | Mortality | Implantation | Risk analysis | Ablation | Patients | Risk factors | Heart valves | Confidence intervals | Hospitals | Fibrillation | Audio frequencies | Surgery | Diabetes | Age
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4. Full Text A robotic platform for flow synthesis of organic compounds informed by AI planning
by Coley, Connor W and Thomas, Dale A and Lummiss, Justin A. M and Jaworski, Jonathan N and Breen, Christopher P and Schultz, Victor and Hart, Travis and Fishman, Joshua S and Rogers, Luke and Gao, Hanyu and Hicklin, Robert W and Plehiers, Pieter P and Byington, Joshua and Piotti, John S and Green, William H and Hart, A. John and Jamison, Timothy F and Jensen, Klavs F
Science (American Association for the Advancement of Science), ISSN 0036-8075, 08/2019, Volume 365, Issue 6453, p. 557
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Intervention | Stoichiometry | Robotics | Complexity | Reactors | Chemists | Configurations | Chemical synthesis | Diazepam | Organic compounds | Solvents | Platforms | Automation | Warfarin | Integration | Aspirin | Antiinflammatory agents | Configuration management | Chemical reactions | Inflammation | Celecoxib | Separators | Secnidazole | Benzodiazepines | Continuous flow | Substrates | Flow | Computer programs | Inlets | User requirements | Organic chemistry | Robot arms | Chemistry | Algorithms | Computer applications | Reagents | Recipes | Software | Lidocaine | Protocol (computers) | Artificial intelligence | Investment | Index Medicus
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5. Full Text Outcome results of the Fosinopril Versus Amlodipine Cardiovascular Events Randomized Trial (FACET) in patients with hypertension and NIDDM
by P Tatti and M Pahor and R P Byington and P Di Mauro and R Guarisco and G Strollo and F Strollo
Diabetes care, ISSN 0149-5992, 04/1998, Volume 21, Issue 4, pp. 597 - 603
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Cardiovascular system | Biological and medical sciences | Medical sciences | Antihypertensive agents | Pharmacology. Drug treatments | Blood Pressure | Body Mass Index | Glycated Hemoglobin A - analysis | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Hypertension - drug therapy | Male | Diabetic Angiopathies - drug therapy | Antihypertensive Agents - therapeutic use | Fosinopril - therapeutic use | Hypertension - physiopathology | Amlodipine - therapeutic use | Diabetic Angiopathies - physiopathology | Diabetes Mellitus, Type 2 - physiopathology | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Time Factors | Fibrinogen - analysis | Lipids - blood | Cholesterol, HDL - blood | Female | Blood Glucose - metabolism | Index Medicus
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6. Full Text The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study
by Bonds, Denise E and Miller, Michael E and Bergenstal, Richard M and Buse, John B and Byington, Robert P and Cutler, Jeff A and Dudl, R James and Ismail-Beigi, Faramarz and Kimel, Angela R and Hoogwerf, Byron and Horowitz, Karen R and Savage, Peter J and Seaquist, Elizabeth R and Simmons, Debra L and Sivitz, William I and Speril-Hillen, Joann M and Sweeney, Mary Ellen
BMJ, ISSN 0959-8138, 2010, Volume 340, Issue 7738, pp. 137 - 137
Blood glucose | RESEARCH | Mortality | Health hazards | Health care industry | Type 2 diabetes mellitus | Cardiovascular diseases | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Hypoglycemia - mortality | Male | Hypertension - prevention & control | Female | Hypertension - mortality | Hypoglycemia - blood | Retrospective Studies | Hypoglycemia - chemically induced | Hypolipidemic Agents - adverse effects | Risk Factors | Diabetic Angiopathies - mortality | Diabetic Angiopathies - blood | Diabetic Angiopathies - drug therapy | Hyperlipidemias - prevention & control | Antihypertensive Agents - adverse effects | Randomized Controlled Trials as Topic | Diabetes Mellitus, Type 2 - blood | Hyperlipidemias - mortality | Diabetes Mellitus, Type 2 - mortality | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Diabetes | Glucose | Hypoglycemia | Index Medicus | Abridged Index Medicus
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7. Full Text Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial
by Sink, Kaycee M and Espeland, Mark A and Castro, Cynthia M and Church, Timothy and Cohen, Ron and Dodson, John A and Guralnik, Jack and Hendrie, Hugh C and Jennings, Janine and Katula, Jeffery and Lopez, Oscar L and McDermott, Mary M and Pahor, Marco and Reid, Kieran F and Rushing, Julia and Verghese, Joe and Rapp, Stephen and Williamson, Jeff D and LIFE Study Investigators
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 08/2015, Volume 314, Issue 8, pp. 781 - 790
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Exercise Therapy - methods | Age Factors | Humans | Male | Treatment Outcome | Sedentary Lifestyle | Dementia - epidemiology | Muscle Stretching Exercises | Cognitive Dysfunction - prevention & control | Resistance Training | Walking | Health Promotion | Cognitive Dysfunction - epidemiology | Aged, 80 and over | Female | Upper Extremity | Aged | Dementia - prevention & control | Executive Function | Health Education | Physical fitness | Cognition & reasoning | Health education | Older people | Index Medicus | Abridged Index Medicus
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8. Full Text Effects of Intensive Blood-Pressure Control in Type 2 Diabetes Mellitus
by Cushman, William C and Evans, Gregory W and Byington, Robert P and Goff Jr, David C and Grimm Jr, Richard H and Cutler, Jeffrey A and Simons-Morton, Denise G and Basile, Jan N and Corson, Marshall A and Probstfield, Jeffrey L and Katz, Lois and Peterson, Kevin A and Friedewald, William T and Buse, John B and Bigger, J. Thomas and Gerstein, Hertzel C and Ismail-Beigi, Faramarz and The ACCORD Study Group and ACCORD Study Group
The New England journal of medicine, ISSN 0028-4793, 04/2010, Volume 362, Issue 17, pp. 1575 - 1585
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Blood Pressure | Myocardial Infarction - epidemiology | Stroke - prevention & control | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Kaplan-Meier Estimate | Proportional Hazards Models | Hypertension - drug therapy | Male | Antihypertensive Agents - therapeutic use | Antihypertensive Agents - adverse effects | Glomerular Filtration Rate - drug effects | Hypokalemia - chemically induced | Cardiovascular Diseases - mortality | Creatinine - blood | Hypertension - complications | Female | Stroke - epidemiology | Aged | Myocardial Infarction - prevention & control | Diabetes Mellitus, Type 2 - drug therapy | Diabetes Mellitus, Type 2 - complications | Type 2 diabetes | Care and treatment | Blood pressure | Cardiovascular diseases | Health aspects | Risk factors | Hypertension | Cardiovascular disease | Diabetes | Index Medicus | Abridged Index Medicus
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