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science & technology (29) 29
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1. Full Text Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer
by Smith, Zachary D and Shi, Jiantao and Gu, Hongcang and Donaghey, Julie and Clement, Kendell and Cacchiarelli, Davide and Gnirke, Andreas and Michor, Franziska and Meissner, Alexander
Nature (London), ISSN 0028-0836, 09/2017, Volume 549, Issue 7673, pp. 543 - 547
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Epigenetic inheritance | Development and progression | Genetic aspects | Somatic cells | Health aspects | Cancer | Ectoderm | Biological evolution | Genomes | Kinases | Mammals | Gene expression | Tissues | Embryos | Proteins | Polycomb group proteins | Signal transduction | Signaling | Placenta | Stem cells | DNA methylation | Epigenetics | Tumorigenesis | Disruption | Methylation | Deoxyribonucleic acid--DNA | CpG islands | Index Medicus
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2. Full Text The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
by Trapnell, Cole and Cacchiarelli, Davide and Grimsby, Jonna and Pokharel, Prapti and Li, Shuqiang and Morse, Michael and Lennon, Niall J and Livak, Kenneth J and Mikkelsen, Tarjei S and Rinn, John L
Nature biotechnology, ISSN 1087-0156, 2014, Volume 32, Issue 4, pp. 381 - 386
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Reproducibility of Results | Gene Expression Regulation - genetics | Genomics | Humans | Muscle Development - physiology | Cells, Cultured | Gene Expression Regulation - physiology | Gene Expression Profiling - methods | Transcriptome - genetics | Transcription Factors - genetics | Transcription Factors - metabolism | Cell Differentiation - genetics | Myoblasts - metabolism | Algorithms | Muscle Development - genetics | Transcriptome - physiology | Cell Differentiation - physiology | Genetic aspects | Cell differentiation | Gene expression | Genetic regulation | Methods | Cells | Time series | Index Medicus
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3. Full Text Dissecting neural differentiation regulatory networks through epigenetic footprinting
by Ziller, Michael J and Edri, Reuven and Yaffe, Yakey and Donaghey, Julie and Pop, Ramona and Mallard, William and Issner, Robbyn and Gifford, Casey A and Goren, Alon and Xing, Jeffrey and Gu, Hongcang and Cacchiarelli, Davide and Tsankov, Alexander M and Epstein, Charles and Rinn, John L and Mikkelsen, Tarjei S and Kohlbacher, Oliver and Gnirke, Andreas and Bernstein, Bradley E and Elkabetz, Yechiel and Meissner, Alexander
Nature (London), ISSN 0028-0836, 02/2015, Volume 518, Issue 7539, pp. 355 - 359
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Embryonic Stem Cells - metabolism | RNA, Small Interfering - genetics | Reproducibility of Results | Embryonic Stem Cells - cytology | Humans | RNA, Small Interfering - analysis | Neural Stem Cells - cytology | Transcription Factors - metabolism | Cell Differentiation - genetics | Epigenomics - methods | Epigenesis, Genetic - genetics | Transcription, Genetic - genetics | Binding Sites | Neural Stem Cells - metabolism | Cell Lineage - genetics | Epigenetic inheritance | Neural circuitry | Stem cells | Genetic research | Genetic aspects | Research | Cell differentiation | Neurological research | Transcription factors | Neurons | Genes | DNA methylation | Epigenetics | Genomes | Alzheimers disease | Binding sites | Index Medicus
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4. Full Text A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA
by Cesana, Marcella and Cacchiarelli, Davide and Legnini, Ivano and Santini, Tiziana and Sthandier, Olga and Chinappi, Mauro and Tramontano, Anna and Bozzoni, Irene
Cell (Cambridge), ISSN 0092-8674, 10/2011, Volume 147, Issue 2, pp. 358 - 369
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Myogenic Regulatory Factors - genetics | RNA Processing, Post-Transcriptional | RNA, Untranslated - metabolism | Humans | MADS Domain Proteins - genetics | Molecular Sequence Data | MicroRNAs - metabolism | Muscle, Skeletal - metabolism | Muscular Dystrophy, Duchenne - pathology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Muscle, Skeletal - cytology | Muscle Development | Myoblasts - metabolism | Animals | Gene Expression Regulation, Developmental | Muscular Dystrophy, Duchenne - embryology | Base Sequence | RNA, Long Noncoding | Mice | Muscular Dystrophy, Duchenne - metabolism | Muscle, Skeletal - embryology | Nuclear Proteins - genetics | MEF2 Transcription Factors | Antisense RNA | DNA binding proteins | Gene expression | Genes | MicroRNA | Genetic transcription | Index Medicus
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5. Full Text Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
by Schwartz, Schraga and Mumbach, Maxwell R and Jovanovic, Marko and Wang, Tim and Maciag, Karolina and Bushkin, G. Guy and Mertins, Philipp and Ter-Ovanesyan, Dmitry and Habib, Naomi and Cacchiarelli, Davide and Sanjana, Neville E and Freinkman, Elizaveta and Pacold, Michael E and Satija, Rahul and Mikkelsen, Tarjei S and Hacohen, Nir and Zhang, Feng and Carr, Steven A and Lander, Eric S and Regev, Aviv
Cell reports (Cambridge), ISSN 2211-1247, 07/2014, Volume 8, Issue 1, pp. 284 - 296
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | RNA Processing, Post-Transcriptional | 5' Untranslated Regions | Humans | Methyltransferases - metabolism | HEK293 Cells | Mice | Methylation | RNA Stability | RNA, Messenger - metabolism | Index Medicus
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6. Full Text miRNAs as serum biomarkers for Duchenne muscular dystrophy
by Cacchiarelli, Davide and Legnini, Ivano and Martone, Julie and Cazzella, Valentina and D'Amico, Adele and Bertini, Enrico and Bozzoni, Irene
EMBO molecular medicine, ISSN 1757-4676, 05/2011, Volume 3, Issue 5, pp. 258 - 265
diagnosis | miRNA | Duchenne Muscular Dystrophy | biomarkers | therapy | Biomarkers | Therapy | Diagnosis | Duchenne muscular dystrophy | MiRNA | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Severity of Illness Index | Animals | Creatine Kinase - blood | Humans | Muscular Dystrophy, Duchenne - pathology | Mice | MicroRNAs - blood | Biomarkers - blood | Muscular Dystrophy, Duchenne - diagnosis | Serum - chemistry | Neuromuscular diseases | Nuclear magnetic resonance--NMR | Disease | Mental disorders | Creatine kinase | Therapeutic applications | Clinical trials | Creatine | Kinases | Patients | Experiments | Muscular dystrophy | Blood levels | Genotype & phenotype | Exon skipping | MicroRNAs | Duchenne's muscular dystrophy | Degeneration | Mutation | Dystrophin | Index Medicus | Life Sciences | Human health and pathology | Creatine Kinase | Biological Markers | Biochemistry, Molecular Biology | Serum | Muscular Dystrophy, Duchenne | Reports
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7. Full Text Triple Vectors Expand AAV Transfer Capacity in the Retina
by Maddalena, Andrea and Tornabene, Patrizia and Tiberi, Paola and Minopoli, Renato and Manfredi, Anna and Mutarelli, Margherita and Rossi, Settimio and Simonelli, Francesca and Naggert, Jurgen K and Cacchiarelli, Davide and Auricchio, Alberto
Molecular therapy, ISSN 1525-0016, 02/2018, Volume 26, Issue 2, pp. 524 - 541
gene therapy | large gene | triple AAV | retina | AAV | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Dependovirus - genetics | Gene Transfer Techniques | Genetic Therapy | Gene Expression | Retina - metabolism | Transduction, Genetic | Cadherins - metabolism | Genetic Vectors - administration & dosage | Humans | Genetic Vectors - genetics | Mice, Knockout | Animals | Gene Expression Regulation, Viral | Recombination, Genetic | Swine | HEK293 Cells | Transcription, Genetic | Mice | Cadherins - genetics | Transgenes | Genes, Reporter | Cytomegalovirus | Gene transfer | Retina | Infections | Genomes | Gene expression | Kinases | Experiments | Electrodes | Proteins | Plasmids | Retinal degeneration | Conflicts of interest | Photoreceptors | Mutation | Localization | Expression vectors | Index Medicus | Original
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8. Full Text Genetic determinants and epigenetic effects of pioneer-factor occupancy
by Donaghey, Julie and Thakurela, Sudhir and Charlton, Jocelyn and Chen, Jennifer S and Smith, Zachary D and Gu, Hongcang and Pop, Ramona and Clement, Kendell and Stamenova, Elena K and Karnik, Rahul and Kelley, David R and Gifford, Casey A and Cacchiarelli, Davide and Rinn, John L and Gnirke, Andreas and Ziller, Michael J and Meissner, Alexander
Nature genetics, ISSN 1061-4036, 02/2018, Volume 50, Issue 2, pp. 250 - 258
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Epigenetic inheritance | Usage | Research | Nucleotide sequencing | Gene expression | DNA sequencing | Binding | Enrichment | Transcription factors | Nucleotide sequence | Oct-4 protein | Genomes | Investigations | Cofactors | Gene sequencing | DNA biosynthesis | Stem cells | DNA methylation | Epigenetics | Fibroblasts | Genetic engineering | Methylation | Deoxyribonucleic acid--DNA | Index Medicus
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