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Journal Article
Bioinformatics, ISSN 1367-4803, 2015, Volume 31, Issue 9, pp. 1515 - 1518
Journal Article
2012, Drug discovery in infectious diseases, ISBN 3527652949, Volume 3
Web Resource
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 01/2016, Volume 10, Issue 1
  Background The Kato-Katz (KK) stool smear is the standard test for the diagnosis of Schistosoma mansoni infection, but suffers from low sensitivity when... 
Studies | Performance evaluation | Urine | Antigens | Substance abuse treatment | Infections | Parasites | Disease control | Eggs
Journal Article
by Van Voorhis, Wesley C and Adams, John H and Adelfio, Roberto and Ahyong, Vida and Akabas, Myles H and Alano, Pietro and Alday, Aintzane and Alemán Resto, Yesmalie and Alsibaee, Aishah and Alzualde, Ainhoa and Andrews, Katherine T and Avery, Simon V and Avery, Vicky M and Ayong, Lawrence and Baker, Mark and Baker, Stephen and Ben Mamoun, Choukri and Bhatia, Sangeeta and Bickle, Quentin and Bounaadja, Lotfi and Bowling, Tana and Bosch, Jürgen and Boucher, Lauren E and Boyom, Fabrice F and Brea, Jose and Brennan, Marian and Burton, Audrey and Caffrey, Conor R and Camarda, Grazia and Carrasquilla, Manuela and Carter, Dee and Belen Cassera, Maria and Chih-Chien Cheng, Ken and Chindaudomsate, Worathad and Chubb, Anthony and Colon, Beatrice L and Colón-López, Daisy D and Corbett, Yolanda and Crowther, Gregory J and Cowan, Noemi and D’Alessandro, Sarah and Le Dang, Na and Delves, Michael and DeRisi, Joseph L and Du, Alan Y and Duffy, Sandra and Abd El-Salam El-Sayed, Shimaa and Ferdig, Michael T and Fernández Robledo, José A and Fidock, David A and Florent, Isabelle and Fokou, Patrick V. T and Galstian, Ani and Gamo, Francisco Javier and Gokool, Suzanne and Gold, Ben and Golub, Todd and Goldgof, Gregory M and Guha, Rajarshi and Guiguemde, W. Armand and Gural, Nil and Guy, R. Kiplin and Hansen, Michael A. E and Hanson, Kirsten K and Hemphill, Andrew and Hooft van Huijsduijnen, Rob and Horii, Takaaki and Horrocks, Paul and Hughes, Tyler B and Huston, Christopher and Igarashi, Ikuo and Ingram-Sieber, Katrin and Itoe, Maurice A and Jadhav, Ajit and Naranuntarat Jensen, Amornrat and Jensen, Laran T and Jiang, Rays H. Y and Kaiser, Annette and Keiser, Jennifer and Ketas, Thomas and Kicka, Sebastien and Kim, Sunyoung and Kirk, Kiaran and Kumar, Vidya P and Kyle, Dennis E and Lafuente, Maria Jose and Landfear, Scott and Lee, Nathan and Lee, Sukjun and Lehane, Adele M and Li, Fengwu and Little, David and Liu, Liqiong and Llinás, Manuel and Loza, Maria I and Lubar, Aristea and Lucantoni, Leonardo and Lucet, Isabelle and Maes, Louis and Mancama, Dalu and ...
PLoS Pathogens, ISSN 1553-7366, 07/2016, Volume 12, Issue 7, pp. e1005763 - e1005763
Journal Article
Nature, ISSN 0028-0836, 07/2009, Volume 460, Issue 7253, pp. 352 - 358
Journal Article
PLoS Medicine, ISSN 1549-1277, 01/2007, Volume 4, Issue 1, pp. 0130 - 0138
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e87594
The mevalonate pathway is essential in eukaryotes and responsible for a diversity of fundamental synthetic activities. 3-hydroxy- 3-methylglutaryl coenzyme A... 
IN-VITRO | ANTISCHISTOSOMAL ACTION | MULTIDISCIPLINARY SCIENCES | HMG-COA REDUCTASE | INHIBITORS | MEVALONATE PATHWAY | PARASITE | MANSONI | CANCER | PROTEIN PRENYLATION | MOLECULAR-MECHANISMS | Mevalonic Acid - pharmacology | Pravastatin - pharmacology | Schistosoma mansoni - drug effects | Schistosoma mansoni - enzymology | Apoptosis - drug effects | Helminth Proteins - biosynthesis | Male | Helminth Proteins - genetics | Hydroxymethylglutaryl CoA Reductases - biosynthesis | Molecular Targeted Therapy | Schistosomiasis mansoni - drug therapy | Simvastatin - pharmacology | Schistosoma mansoni - genetics | Gene Knockdown Techniques | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Schistosomiasis mansoni - parasitology | RNA Interference | Anthelmintics - pharmacology | Inhibitory Concentration 50 | Female | Mice | Drug Evaluation, Preclinical | Hydroxymethylglutaryl CoA Reductases - genetics | Schistosomiasis | Enzymes | Hypercholesterolemia | Machine learning | Drug therapy | Health aspects | Statins | Killing | Drugs | RNA-mediated interference | Simvastatin | Caspase | Lethality | Parasites | Pravastatin | Drug development | Kinases | Gene expression | Learning algorithms | Eukaryotes | Mevalonic acid | Ribonucleic acids | Parasitic diseases | Hydroxymethylglutaryl-CoA reductase | Coenzyme A | Lipophilicity | Apoptosis
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