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British Journal of Pharmacology, ISSN 0007-1188, 03/2010, Volume 159, Issue 6, pp. 1236 - 1246
Background and purpose:  Hydrogen sulphide is an important mediator of gastric mucosal defence. The use of non-steroidal anti-inflammatory drugs continues to... 
gastrointestinal | naproxen | blood pressure | arthritis | inflammation | cyclooxygenase | ulcer | hydrogen sulphide | non-steroidal anti-inflammatory drug | mucosal defence | non‐steroidal anti‐inflammatory drug | Hydrogen sulphide | Cyclooxygenase | Mucosal defence | Naproxen | Non-steroidal anti-inflammatory drug | Ulcer | Arthritis | Blood pressure | Inflammation | Gastrointestinal | RHEUMATOID-ARTHRITIS | MUCOSAL LESIONS | OXIDE DONATOR NAPROXCINOD | GASTROINTESTINAL-TRACT | BLOOD-PRESSURE | SELECTIVE CYCLO-OXYGENASE-2 INHIBITORS | GASTRIC DAMAGE | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | GROWTH-FACTOR | Hydrogen Sulfide - metabolism | Naproxen - analogs & derivatives | Arthritis, Experimental - drug therapy | Intestinal Mucosa - metabolism | Rats, Wistar | Dinoprostone - biosynthesis | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Gastric Mucosa - metabolism | Intestinal Mucosa - drug effects | Stomach Ulcer - enzymology | Arthritis, Experimental - metabolism | Intestine, Small - enzymology | Naproxen - pharmacokinetics | Intestinal Mucosa - enzymology | Gastric Mucosa - drug effects | Blood Pressure - drug effects | Molecular Structure | Hypertension - enzymology | Naproxen - analysis | Naproxen - adverse effects | Stomach Ulcer - metabolism | Gastric Mucosa - enzymology | Stomach Ulcer - drug therapy | Rats | Naproxen - therapeutic use | Hypertension - metabolism | Naproxen - chemistry | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Intestine, Small - drug effects | Cyclooxygenase 2 - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Mice | Arthritis, Experimental - enzymology | Cyclooxygenase 1 - metabolism | Intestine, Small - metabolism | Toxicity | Rodents | Ulcers | Research Papers
Journal Article
Journal Article
Journal Article
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 04/2019, Volume 10, p. 432
Neurounina-1 [chemical name: 7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[e][1,4]diazepin-2(3H)-one] is a new compound provided with relevant... 
LC-MS/MS | Na+/Ca2+ exchanger (NCX) | NCX3 | beagle dog plasma | NA+/CA2+ EXCHANGER | pharmacokinetics | neurounina-1 | PHARMACOLOGY & PHARMACY | CEREBRAL-ISCHEMIA | Liquid chromatography | Mass spectrometry | Analysis | Methods
Journal Article
CURRENT PHARMACEUTICAL DESIGN, ISSN 1381-6128, 2019, Volume 25, Issue 9, pp. 956 - 968
Background: Sphingosine kinases (SphKs) catalyze the phosphorylation of sphingosine to form the bioactive sphingolipid metabolite sphingosine-1-phosphate... 
DIHYDROCERAMIDE DESATURASE | 1 SELECTIVE INHIBITOR | dual inhibitors | CELL-GROWTH | ANTITUMOR-ACTIVITY | FTY720 ANALOGS | Sphingosine Kinase 2 | selective inhibitors | Sphingosine Kinase 1 | BREAST-CANCER | PROTEASOMAL-DEGRADATION | IN-VITRO | Sphingosine-1-phosphate | design | ARTERY SMOOTH-MUSCLE | BIOLOGICAL EVALUATION | PHARMACOLOGY & PHARMACY
Journal Article
Cardiovascular Therapeutics, ISSN 1755-5914, 04/2016, Volume 34, Issue 2, pp. 76 - 84
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, p. 34398
Hydrogen sulfide is an essential catabolite that intervenes in the pathophysiology of several diseases from hypertension to stroke, diabetes and pancreatitis.... 
METABOLOMICS | RAT | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | MOUSE | H2S | BETA-SYNTHASE
Journal Article
Modern Pathology, ISSN 0893-3952, 11/2011, Volume 24, Issue 11, pp. 1451 - 1461
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2000, Volume 97, Issue 7, pp. 3678 - 3683
Protease-activated receptor-2 (PAR-2) is a member of seven transmembrane domain G protein-coupled receptors activated by proteolytic cleavage whose better... 
Heart | Biological Sciences | Receptors | Reactive oxygen species | Reperfusion | Ischemia | Data encryption | Mathematical independent variables | C