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Journal of Chemical Education, ISSN 0021-9584, 09/2019
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 04/2019, Volume 25, Issue 21, p. n/a
Despite extensive quantities of work with regard to reactivation of organophosphorus‐inhibited and aged acetylcholinesterase (AChE) and butyrylcholinesterase... 
acetylcholinesterase | reactivation | butyrylcholinesterase | organophosphorus | resurrection | Cholinergics | Oximes | Activation | Acetylcholinesterase
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 06/2016, Volume 1374, Issue 1, pp. 94 - 104
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 6/2016, Volume 1374, Issue 1, pp. 94 - 104
Aging is a dealkylation reaction of organophosphorus (OP)-inhibited acetylcholinesterase (AChE). Despite many studies to date, aged AChE cannot be reactivated... 
upregulation | acetylcholinesterase | aging | realkylation | resurrection | exogenous
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2018, Volume 61, Issue 16, pp. 7034 - 7042
After the inhibition of acetylcholinesterase (AChE) by organophosphorus (OP) nerve agents, a dealkylation reaction of the phosphylated serine, referred to as... 
OXIMES | CHEMISTRY, MEDICINAL | QUINONE METHIDE | SODIUM-FLUORIDE | ALKYLATION | KINETIC-ANALYSIS | REACTIVITY | INHIBITED ACETYLCHOLINESTERASE | CHOLINESTERASES | PROTEINS
Journal Article
Chemistry (Weinheim an der Bergstrasse, Germany), 11/2018
Organophosphorus (OP) nerve agents and pesticides present significant threats to civilian and military populations. OP compounds include the nefarious G and V... 
Journal Article
Journal of Pain, ISSN 1526-5900, 2011, Volume 12, Issue 2, pp. 297 - 303
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2003, Volume 125, Issue 43, pp. 13112 - 13119
We report here the combined use of computational chemistry and low-temperature NMR spectroscopy to probe the mechanism of a highly stereoselective... 
DENSITY | CHEMISTRY, MULTIDISCIPLINARY | LINKAGES | Sulfoxides - chemistry | Thermodynamics | Cold Temperature | Furans - chemistry | Stereoisomerism | Glycosides - chemical synthesis | Nuclear Magnetic Resonance, Biomolecular | Sulfoxides - metabolism | Glycosylation | Glycosides - chemistry
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 08/2012, Volume 16, Issue 8, pp. 1900 - 1915
Many patients suffer from chronic gastrointestinal diseases characterized by chronic inflammation, increased intestinal permeability and visceral pain in which... 
intestinal permeability | stem cell | IL‐10−/− mice | cytokines | inflammatory bowel disease (IBD) | TNF‐α and IFN‐γ | visceral hypersensitivity | Cytokines | Inflammatory bowel disease (IBD) | Visceral hypersensitivity | Stem cell | Intestinal permeability | TNF-α and IFN-γ | mice | IL-10 | MEDICINE, RESEARCH & EXPERIMENTAL | DISTENSION | RATS | RECIPIENTS | TNF-a and IFN | CELL BIOLOGY | SOMATIC HYPERSENSITIVITY | NOXIOUS VISCERAL STIMULUS | ENGRAFTMENT | INFLAMMATORY-BOWEL-DISEASE | ACID (TNBS)-INDUCED COLITIS | MYOFIBROBLASTS | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Cell Proliferation | Colitis - complications | Colitis - pathology | Male | Hypersensitivity - complications | Interferon-gamma - metabolism | Stem Cell Transplantation | Inflammation - complications | Colitis - therapy | Colon - physiopathology | Viscera - physiopathology | Pluripotent Stem Cells - cytology | Colon - pathology | Mice, Inbred C57BL | Permeability | Viscera - pathology | Regeneration | Animals | Colitis - physiopathology | Hypersensitivity - physiopathology | Hypersensitivity - pathology | Mice | In Vitro Techniques | Cell Movement | Inflammation - physiopathology | Stem cell research | Neurosciences | Gastrointestinal diseases | Stem cells | Transplantation | Colitis | Gene expression | Health aspects | Gastrointestinal tract diseases | Epithelial cells | Stem cell transplantation | Cell adhesion & migration | Infusion | Pain | Restoration | Intestine | Colon | Immune system | Signs and symptoms | Wound healing | Tissue engineering | Hypersensitivity | Inflammation | Inflammatory bowel disease | Studies | Refractory materials | Side effects | Correlation analysis | Irritable bowel syndrome | Original
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 06/2017, Volume 8, Issue 6, pp. 622 - 627
Acetylcholinesterase (AChE) is an essential enzyme 2N that can be targeted by organophosphorus (OP) compounds, including nerve agents. Following exposure to... 
quinone methide | Acetylcholinesterase | organophosphorus chemical nerve agents | CHOLINESTERASE | CHEMISTRY, MEDICINAL | OXIME EFFICACY | ALKYLATION | SUBSTITUENTS | MODEL | PESTICIDES | REACTIVATION | SARIN | AGENTS | ORGANOPHOSPHORUS COMPOUNDS
Journal Article
Journal Article
Journal of Cellular and Molecular Medicine (Online), 08/2012, Volume 16, Issue 8, p. 1900
Many patients suffer from chronic gastrointestinal diseases characterized by chronic inflammation, increased intestinal permeability and visceral pain in which... 
Inflammatory bowel disease | Transplants & implants | Gastrointestinal diseases | Rodents | Stem cells | Permeability
Journal Article
Organic Letters, ISSN 1523-7060, 02/2001, Volume 3, Issue 4, pp. 607 - 610
[GRAPHICS] The stereocontrolled synthesis of 2,3-anhydro-beta -D-lyxofuranosyl glycosides from thioglycoside 2 and glycosyl sulfoxide 3 is reported. 
BETA-MANNOPYRANOSIDES | THIOGLYCOSIDES | OLIGOSACCHARIDES | LIPOARABINOMANNAN | CHEMISTRY, ORGANIC | GLYCALS | STEREOSPECIFIC SYNTHESIS | DONORS | GLYCOSYLATION | STRATEGIES | Glycosylation | Molecular Structure | Thioglycosides - chemistry | Stereoisomerism | Glycosides - chemistry | Glycosides - chemical synthesis
Journal Article
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