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PEDIATRIC RHEUMATOLOGY, ISSN 1546-0096, 08/2019, Volume 17, Issue 1, pp. 57 - 10
Background The anti-interleukin-6 receptor-alpha antibody tocilizumab was approved for intravenous (IV) injection in the treatment of patients with systemic... 
PEDIATRICS | Biological therapy | Inflammation | RHEUMATOLOGY | Pharmacokinetics | Juvenile idiopathic arthritis | Viral antibodies | Interleukins | Clinical trials | Antibodies | Arthritis | Product development | Comparative analysis
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2018, Volume 378, Issue 20, pp. 1908 - 1919
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 2016, Volume 68, Issue 11, pp. 2795 - 2805
Objective Mevalonate kinase deficiency (MKD) is a rare metabolic disease characterized by recurrent inflammatory episodes. This study was undertaken to... 
MVK | HYPER-IGD | PERIODIC FEVER SYNDROME | ACIDURIA | HYPERIMMUNOGLOBULINEMIA-D | AUTOINFLAMMATORY DISEASES | MUTATIONS | SPECTRUM | RHEUMATOLOGY | Arthralgia - etiology | Uveitis - etiology | Humans | Child, Preschool | Lymphadenopathy - etiology | Male | Arthralgia - physiopathology | Arthritis - genetics | Stomatitis, Aphthous - genetics | Cerebellar Diseases - physiopathology | Amyloidosis - genetics | Skin Diseases - physiopathology | Amyloidosis - etiology | Child | Stomatitis, Aphthous - etiology | Infant, Newborn | Myalgia - physiopathology | Amyloidosis - physiopathology | Genotype | Headache - physiopathology | Vomiting - genetics | Phenotype | Diarrhea - genetics | Abdominal Pain - genetics | Adolescent | Age of Onset | Intellectual Disability - etiology | Uveitis - genetics | Vomiting - physiopathology | Conjunctivitis - etiology | Conjunctivitis - genetics | Arthritis - physiopathology | Headache - etiology | Skin Diseases - genetics | Mevalonate Kinase Deficiency - physiopathology | Myalgia - genetics | Cerebellar Diseases - etiology | Diarrhea - physiopathology | Infant | Mevalonate Kinase Deficiency - genetics | Intellectual Disability - genetics | Pharyngitis - genetics | Arthritis - etiology | Female | Registries | Retrospective Studies | Arthralgia - genetics | Pharyngitis - physiopathology | Abdominal Pain - etiology | Pharyngitis - etiology | Lymphadenopathy - genetics | Abdominal Pain - physiopathology | Myalgia - etiology | Phosphotransferases (Alcohol Group Acceptor) - genetics | Headache - genetics | Intellectual Disability - physiopathology | Skin Diseases - etiology | Cerebellar Diseases - genetics | Conjunctivitis - physiopathology | Mevalonate Kinase Deficiency - complications | Stomatitis, Aphthous - physiopathology | Vomiting - etiology | Diarrhea - etiology | Lymphadenopathy - physiopathology | Uveitis - physiopathology | Kinases | Genotype & phenotype | Index Medicus | Abridged Index Medicus
Journal Article
Pediatric Rheumatology, ISSN 1546-0096, 2014, Volume 12, Issue Suppl 1, pp. P266 - P266
Journal Article
Pediatric Rheumatology, ISSN 1546-0096, 2014, Volume 12, Issue Suppl 1, p. P283
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2018, Volume 77, Issue Suppl 2, p. 499
BackgroundIntravenous (IV) tocilizumab (TCZ) was approved in the, US (2011), EU (2013) and other countries for the treatment of systemic juvenile idiopathic... 
Thrombocytopenia | Intravenous administration | Hypersensitivity | Liver | Arthritis | Hand-foot-and-mouth disease | Inflammation | Histiocytosis | Patients | Vomiting | Respiratory tract diseases | Foot-and-mouth disease | Safety | Pharmacokinetics | Drug dosages | Age | Neutropenia
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 133
BackgroundTocilizumab (TCZ) is approved for the treatment of systemic juvenile idiopathic arthritis (sJIA) based on clinical trials in patients (pts) ≥2 years... 
Corticoids | Pharmacodynamics | Hypersensitivity | Body weight | Clinical trials | Arthritis | Patients | Interleukin 6 | Interleukin 6 receptors | Foot-and-mouth disease | Children | Safety | Nonsteroidal anti-inflammatory drugs | Pharmacokinetics | Age
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2008, Volume 67, Issue 3, pp. 309 - 314
Journal Article
Lancet, The, ISSN 0140-6736, 2008, Volume 372, Issue 9636, pp. 383 - 391
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 05/2013, Volume 72, Issue 5, pp. 686 - 693
Journal Article
Pediatric Rheumatology, ISSN 1546-0096, 12/2011, Volume 9, Issue S1, p. P194
Journal Article
JOURNAL OF RHEUMATOLOGY, ISSN 0315-162X, 04/2016, Volume 43, Issue 4, pp. 816 - 824
Journal Article
Arthritis Care & Research, ISSN 2151-464X, 11/2010, Volume 62, Issue 11, pp. 1542 - 1551
Journal Article