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by Ehret, Georg B and Ferreira, Teresa and Chasman, Daniel I and Jackson, Anne U and Schmidt, Ellen M and Johnson, Toby and Thorleifsson, Gudmar and Luan, Jian'an and Donnelly, Louise A and Kanoni, Stavroula and Petersen, Ann-Kristin and Pihur, Vasyl and Strawbridge, Rona J and Shungin, Dmitry and Hughes, Maria F and Meirelles, Osorio and Kaakinen, Marika and Bouatia-Naji, Nabila and Kristiansson, Kati and Shah, Sonia and Kleber, Marcus E and Guo, Xiuqing and Lyytikäinen, Leo-Pekka and Fava, Cristiano and Eriksson, Niclas and Nolte, Ilja M and Magnusson, Patrik K and Salfati, Elias L and Rallidis, Loukianos S and Theusch, Elizabeth and Smith, Anew J. P and Folkersen, Lasse and Witkowska, Kate and Pers, Tune H and Joehanes, Roby and Kim, Stuart K and Lataniotis, Lazaros and Jansen, Rick and Johnson, Anew D and Warren, Helen and Kim, Young Jin and Zhao, Wei and Wu, Ying and Tayo, Bamidele O and Bochud, Murielle and Absher, Devin and Adair, Linda S and Amin, Najaf and Arking, Dan E and Axelsson, Tomas and Baldassarre, Damiano and Balkau, Beverley and Bandinelli, Stefania and Barnes, Michael R and Barroso, Inês and Bevan, Stephen and Bis, Joshua C and Bjornsdottir, Gyda and Boehnke, Michael and Boerwinkle, Eric and Bonnycastle, Lori L and Boomsma, Dorret I and Bornstein, Stefan R and Brown, Morris J and Burnier, Michel and Cabrera, Claudia P and Chambers, John C and Chang, I.-Shou and Cheng, Ching-Yu and Chines, Peter S and Chung, Ren-Hua and Collins, Francis S and Connell, John M and Döring, Angela and Dallongeville, Jean and Danesh, John and de Faire, Ulf and Delgado, Graciela and Dominiczak, Anna F and Doney, Alex S. F and nos, Fotios and Edkins, Sarah and Eicher, John D and Elosua, Roberto and Enroth, Stefan and Erdmann, Jeanette and Eriksson, Per and Esko, Tonu and Evangelou, Evangelos and Evans, Alun and Fall, Tove and Farrall, Martin and Felix, Janine F and Ferrières, Jean and Ferrucci, Luigi and Fornage, Myriam and Forrester, Terrence and Franceschini, Nora and Franco, Oscar H and Franco-Cereceda, Anders and ... and CHARGE-HF Consortium and Wellcome Trust Case Control Consor and CHARGE-EchoGen Consortium and Wellcome Trust Case Control Consortium and Medicinska fakulteten and Avdelningen för medicin and Umeå universitet and Medicin and Institutionen för odontologi and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Näringsforskning
Nature genetics, ISSN 1061-4036, 2016, Volume 48, Issue 10, pp. 1171 - 1184
To dissect the genetic architecture of blood pressure and assess effects on target organ damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays... 
COMMON VARIANTS | METAANALYSIS | SUSCEPTIBILITY | GENETICS & HEREDITY | LOCI | TRAITS | HYPERTENSION | GENOME-WIDE ASSOCIATION | Studies | Consortia | Hypotheses | Genealogy | Genetics | Blood pressure | Genomes | Meta-analysis | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Wilk, Jemma and Shrine, Nick and Loehr, Laura and Zhao, Jing Hua and Manichaikul, Ani and Lopez, Lorna and Smith, Davey and Heckbert, Susan and Smolonska, Joanna and Tang, Wenbo and Loth, Daan and Curjuric, Ivan and Hui, Jennie and Cho, Michael and Latourelle, Jeanne and Henry, Amanda and Alich, Melinda and Bakke, Arnold B and Beaty, Terri and Bentley, Amy and Borecki, Ingrid and Brusselle, Guy and Burkart, Kristin and Chen, T.H and Couper, David and Crapo, Robert and Davies, Gail and Dupuis, Josée and Franceschini, Nora and Gulsvik, Amund and Hancock, Dana and Harris, Tamara and Hofman, Albert and Imboden, Medea and James, Alan and Khaw, Kay-Tee and Lahousse, Lies and Launer, Lenore and Litonjua, Augusto and Liu, YongMei and Lohman, Kurt and Lomas, David John and Lumley, Thomas and Marciante, Kristin and McArdle, Wendy and Meibohm, Bernd and Morrison, Alanna and Musk, Arthur and Myers, Richard and North, Kari and Postma, Dirkje and Psaty, Bruce and Rich, Stephen and Rivadeneira Ramirez, Fernando and Rochat, Thierry and Rotter, Jerome and Soler Artigas, Maria and Starr, John and Uitterlinden, Ané and Wareham, Nick and Wijmenga, Cisca and Zanen, Pieter and Province, Mike and Silverman, Edwin and Deary, Ian and Palmer, Cameron and Cassano, Patricia and Gudnason, Vilmundur and Barr, Graham and Loos, Ruth and Strachan, David and London, Stephanie and Boezen, Marike and Probst-Hensch, Nicole and Gharib, Sina and Hall, Ian and O'Connor, George and Tobin, Martin and Stricker, Bruno
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 10/2012, Volume 186, Issue 7, pp. 622 - 632
Journal Article
by Tang, Wenbo and Kowgier, Matthew and Loth, Daan and Soler Artigas, Maria and Joubert, Bonnie and Hodge, Emily and Gharib, Sina and Smith, Davey and Ruczinski, Ingo and Gudnason, Vilmundur and Mathias, Jasmine and Harris, Tamara and Hansel, Christian and Launer, Lenore and Barnes, Kathleen and Hansen, Joyanna and Albrecht, Eva and Alich, Melinda and Allerhand, Michael and Barr, Graham and Brusselle, Guy and Couper, David and Curjuric, Ivan and Davies, Gail and Deary, Ian and Dupuis, Josée and Fall, Magnus and Foy, Millennia and Franceschini, Nora and Gao, Wei and Gläser, Sven and Gu, Xiangjun and Hancock, Dana and Heinrich, Joachim and Hofman, Albert and Imboden, Medea and Ingelsson, Erik and James, Alan and Karrasch, Stefan and Koch, Beate and Kritchevsky, Stephen and Kumar, Ashish and Lahousse, Lies and Li, Guo and Lind, Lars and Lindgren, Cecilia and Liu, YongMei and Lohman, Kurt and Lumley, Thomas and McArdle, Wendy and Meibohm, Bernd and Morris, Anew and Morrison, Alanna and Musk, Arthur and North, Kari and Palmer, Cameron and Probst-Hensch, Nicole M and Psaty, Bruce and Rivadeneira Ramirez, Fernando and Rotter, Jerome and Schulz, Holger and Smith, Lewis and Sood, Akshay and Starr, John and Strachan, David and Teumer, Alexander and Uitterlinden, Ané and Völzke, Henry and Voorman, Jeanine and Wain, Louise and Wells, Martin and Wilk, Jemma and Williams, Dale and Heckbert, Susan and Stricker, Bruno and London, Stephanie and Fornage, Myriam and Tobin, Martin and O'Connor, George and Hall, Ian and Cassano, Patricia and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, p. e100776
Background: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes... 
GLOBAL BURDEN | FUNCTION DECLINE | HEARING-LOSS | PROTEIN | GENE | INTERLEUKIN-16 | MULTIDISCIPLINARY SCIENCES | DISEASE | ASTHMA | POLYMORPHISM | EXPRESSION | Genome-Wide Association Study | Humans | Gene Expression Regulation | Adult | Female | Male | Chromosomes, Human, Pair 11 - genetics | Respiration - genetics | Genetic Loci | Longitudinal Studies | Lung diseases, Obstructive | Genomes | Gene expression | Analysis | Genomics | Biometrics | Heart | Health sciences | Respiratory function | Thoracic surgery | Demography | Laboratories | Genes | Critical care | Population studies | Lipids | Steroidogenic acute regulatory protein | Tissues | Epidemiology | Proteins | Immunology | Genetic analysis | Interleukin 1 | Chromosome 11 | Aging | Genetics | Chronic obstructive pulmonary disease | Chromosome 15 | Genotypes | Public health | Medical research | Enzymes | Cytokines | Environmental health | Interleukin 16 | Loci | Asthma | Medicine | Hospitals | DNA microarrays | Lungs | Adults | Smoking | Clinical Medicine | Medical Biotechnology | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | Lungmedicin och allergi | Klinisk medicin | Respiratory Medicine and Allergy | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci)
Journal Article
by Adlam, David and Olson, Timothy M and Combaret, Nicolas and Kovacic, Jason C and Iismaa, Siiri E and Al-Hussaini, Abtehale and O'Byrne, Megan M and Bouajila, Sara and Georges, Adrien and Mishra, Ketan and Braund, Peter S and d’Escamard, Valentina and Huang, Siying and Margaritis, Marios and Nelson, Christopher P and de Andrade, Mariza and Kadian-Dodov, Daniella and Welch, Catherine A and Mazurkiewicz, Stephani and Jeunemaitre, Xavier and Motreff, Pascal and Belle, Loïc and Dupouy, Patrick and Barnay, Pierre and Meneveau, Nicolas and Gilard, Martine and Rioufol, Gilles and Range, Grégoire and Brunel, Philippe and Delarche, Nicolas and Filippi, Emmanuelle and Le Bivic, Louis and Harbaoui, Brahim and Benamer, Hakim and Cayla, Guillaume and Varenne, Olivier and Manzo-Silberman, Stephane Peggy and Silvain, Johanne and Spaulding, Christian and Caussin, Christophe and Gerbaud, Edouard and Valy, Yann and Koning, René and Lhermusier, Thibault and Champin, Stanislas and Salengro, Emmanuel and Fluttaz, Arnaud and Zabalawi, Amer and Cottin, Yves and Teiger, Emmanuel and Saint-Etienne, Christophe and Ducrocq, Grégory and Marliere, Stéphanie and Boiffard, Emmanuel and Aubry, Pierre and Georges, Jean Louis and Bresson, Didier and De Poli, Fabien and Karrillon, Gaëtan and Roule, Vincent and Bali, Laurent and Valla, Mathieu and Gerbay, Antoine and Houpe, David and Dubreuil, Olivier and Monnier, Arsène and Mayaud, Norbert and Manchuelle, Aurélie and Commeau, Philippe and Bedossa, Marc and Wong, Claire Mei Yi and Giannoulatou, Eleni and Sweeting, Michael and Muller, David and Wood, Alice and McGrath-Cadell, Lucy and Fatkin, Diane and Dunwoodie, Sally L and Harvey, Richard and Holloway, Cameron and Empana, Jean-Philippe and Jouven, Xavier and Nikpay, Majid and Goel, Anuj and Won, Hong-Hee and Hall, Leanne M and Willenborg, Christina and Kanoni, Stavroula and Saleheen, Danish and Kyriakou, Theodosios and Nelson, Christopher P and Hopewell, Jemma C and Webb, Thomas R and Zeng, Lingyao and Dehghan, Abbas and Alver, Maris and Armasu, Sebastian M and Auro, Kirsi and Bjonnes, Andrew and Chasman, Daniel I and ... and CARDIoGRAMPlusC4D Study Group and DISCO Consortium and CARDIoGRAMPlusC4D Study Grp
Journal of the American College of Cardiology, ISSN 0735-1097, 01/2019, Volume 73, Issue 1, pp. 58 - 66
Journal Article
by Simino, Jeannette and Shi, Gang and Bis, Joshua C and Chasman, Daniel I and Ehret, Georg B and Gu, Xiangjun and Guo, Xiuqing and Hwang, Shih-Jen and Sijbrands, Eric and Smith, Albert V and Verwoert, Germaine C and Bragg-Gresham, Jennifer L and Cadby, Gemma and Chen, Peng and Cheng, Ching-Yu and Corre, Tanguy and de Boer, Rudolf A and Goel, Anuj and Johnson, Toby and Khor, Chiea-Chuen and Alizadeh, Behrooz Z and de Boer, Rudolf A and Boezen, H. Marike and Bruinenberg, Marcel and Franke, Lude and van der Harst, Pim and Hillege, Hans L and van der Klauw, Melanie M and Navis, Gerjan and Ormel, Johan and Postma, Dirkje S and Rosmalen, Judith G.M and Slaets, Joris P and Snieder, Harold and Stolk, Ronald P and Wolffenbuttel, Bruce H.R and Wijmenga, Cisca and Lluís-Ganella, Carla and Luan, Jian’an and Lyytikäinen, Leo-Pekka and Nolte, Ilja M and Sim, Xueling and Sõber, Siim and van der Most, Peter J and Verweij, Niek and Zhao, Jing Hua and Amin, Najaf and Boerwinkle, Eric and Bouchard, Claude and Dehghan, Abbas and Eiriksdottir, Gudny and Elosua, Roberto and Franco, Oscar H and Gieger, Christian and Harris, Tamara B and Hercberg, Serge and Hofman, Albert and James, Alan L and Johnson, Andrew D and Kähönen, Mika and Khaw, Kay-Tee and Kutalik, Zoltan and Larson, Martin G and Launer, Lenore J and Li, Guo and Liu, Jianjun and Liu, Kiang and Morrison, Alanna C and Navis, Gerjan and Ong, Rick Twee-Hee and Papanicolau, George J and Penninx, Brenda W and Psaty, Bruce M and Raffel, Leslie J and Raitakari, Olli T and Rice, Kenneth and Rivadeneira, Fernando and Rose, Lynda M and Sanna, Serena and Scott, Robert A and Siscovick, David S and Stolk, Ronald P and Uitterlinden, Andre G and Vaidya, Dhananjay and van der Klauw, Melanie M and Vasan, Ramachandran S and Vithana, Eranga Nishanthie and Völker, Uwe and Völzke, Henry and Watkins, Hugh and Young, Terri L and Aung, Tin and Bochud, Murielle and Farrall, Martin and Hartman, Catharina A and Laan, Maris and Lakatta, Edward G and Lehtimäki, Terho and Loos, Ruth J.F and Lucas, Gavin and ... and LifeLines Cohort Study
The American Journal of Human Genetics, ISSN 0002-9297, 07/2014, Volume 95, Issue 1, pp. 24 - 38
Although age-dependent effects on blood pressure (BP) have been reported, they have not been systematically investigated in large-scale genome-wide association... 
POPULATION | METAANALYSIS | VARIANTS | ENVIRONMENT INTERACTIONS | DISEASE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | HYPERTENSION | INTERACTIONS IDENTIFY | FIBRINOGEN | GENOME-WIDE ASSOCIATION | Young Adult | Age Factors | Blood Pressure - genetics | Humans | Middle Aged | Adolescent | Adult | Aged | Cohort Studies | Genetic research | Blood pressure | Genetic aspects | Research | Gene expression | Health aspects
Journal Article
Journal Article
by Locke, A.E and Kahali, B and Berndt, S.I and Justice, A.E and Pers, T.H and Day, F.R and Powell, C and Vedantam, S and Buchkovich, M.L and Yang, J and Croteau-Chonka, D.C and Esko, T and Fall, T and Ferreira, T and Gustafsson, S and Kutalik, Z and Luan, J and Magi, R and Randall, J.C and Winkler, T.W and Wood, A.R and Workalemahu, T and Faul, J.D and Smith, J.A and Zhao, J and Zhao, W and Chen, J and Fehrmann, R and Hedman, A.K and Karjalainen, J and Schmidt, E.M and Absher, D and Amin, N and Anderson, D and Beekman, M and Bolton, J.L and Bragg-Gresham, J.L and Buyske, S and Demirkan, A and Deng, G and Ehret, G.B and Feenstra, B and Feitosa, M.F and Fischer, K and Goel, A and Gong, J and Jackson, A.U and Kanoni, S and Kleber, M.E and Kristiansson, K and Lim, U and Lotay, V and Mangino, M and Leach, I. Mateo and Medina-Gomez, C and Medland, S.E and Nalls, M.A and Palmer, C.D and Pasko, D and Pechlivanis, S and Peters, M.J.W and Prokopenko, I and Shungin, D and Stancakova, A and Strawbridge, R.J and Sung, Y. Ju and Tanaka, T and Teumer, A and Trompet, S and Laan, S.W. van der and Setten, J. van and Vliet-Ostaptchouk, J.V. Van and Wang, Z and Yengo, L and Zhang, W and Isaacs, A and Albrecht, E and Arnlov, J and Arscott, G.M and Attwood, A.P and Bandinelli, S and Barrett, A and Bas, I.N and Bellis, C and Bennett, A.J and Berne, C and Blagieva, R and Bluher, M and Bohringer, S and Bonnycastle, L.L and Bottcher, Y and Boyd, H.A and Bruinenberg, M and Caspersen, I.H and Chen, Y.D and Clarke, R and Daw, E.W and Craen, A.J. de and Delgado, G and Dimitriou, M and ... and ADIPOGen Consortium and PAGE Consortium and LifeLines Cohort Study and MIGen Consortium and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and CKDGen Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and AGEN-BMI Working Grp and GLGC and International Endogene Consortium and AGEN-BMI Working Group and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GLGC and The GENIE Consortium and The AGEN-BMI Working Group and The MIGen Consortium and The MuTHER Consortium and The LifeLines Cohort Study and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Medicinsk genetik och genomik and Geriatrik and Uppsala universitet and Klinisk diabetologi och metabolism and Institutionen för immunologi, genetik och patologi and Molekylär medicin and Kardiovaskulär epidemiologi and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Institutionen för folkhälso- och vårdvetenskap
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7538, pp. 197 - 206
Journal Article