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American Journal of Physiology, ISSN 1040-0605, 11/2015, Volume 309, Issue 9, p. L983
  Inflammatory mediators released in acute lung injury (ALI) trigger the disruption of interendothelial junctions, leading to loss of vascular barrier... 
Proteins | Wound healing | Lungs | Respiratory diseases | Genetics | Injuries
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2018, Volume 28, Issue 23-24, pp. 3585 - 3591
Sphingolipids represent an essential class of lipids found in all eukaryotes, and strongly influence cellular signal transduction. Autoimmune diseases like... 
S1P1 agonists | Sphingolipids | Sphingosine-1-phosphate receptor 1 | Sphingosine-1-phosphate | Autoimmune modulators | S1P | agonists | S1P AGONIST | S1P agonists | CHEMISTRY, MEDICINAL | ANALOG AAL-R | ORAL FINGOLIMOD FTY720 | CHEMISTRY, ORGANIC | LYMPHOCYTE EGRESS | IMMUNOMODULATORY DRUG FTY720 | SPHINGOSINE 1-PHOSPHATE RECEPTOR-1 | REMITTING MULTIPLE-SCLEROSIS | PROTEIN-COUPLED RECEPTOR | BIOLOGICAL EVALUATION | SELECTIVE AGONIST | Receptors, Lysosphingolipid - antagonists & inhibitors | Humans | Immunosuppressive Agents - pharmacokinetics | Immunosuppressive Agents - therapeutic use | Biological Availability | Sphingolipids - metabolism | Oxadiazoles - therapeutic use | Fingolimod Hydrochloride - chemistry | Multiple Sclerosis - pathology | Receptors, Lysosphingolipid - agonists | Oxadiazoles - chemistry | Oxadiazoles - pharmacokinetics | Receptors, Lysosphingolipid - metabolism | Autoimmune Diseases - metabolism | Autoimmune Diseases - pathology | Autoimmune Diseases - drug therapy | Fingolimod Hydrochloride - pharmacokinetics | Fingolimod Hydrochloride - therapeutic use | Immunosuppressive Agents - chemistry | Multiple Sclerosis - drug therapy | Multiple Sclerosis - metabolism | Phosphates | Multiple sclerosis | Sphingosine | Physiological aspects | Lipids | Cellular signal transduction | G proteins | Epidemiology | Membrane proteins
Journal Article
Journal Article
Critical care (London, England), ISSN 1364-8535, 12/2019, Volume 23, Issue 1, pp. 410 - 8
There is a compelling unmet medical need for biomarker-based models to risk-stratify patients with acute respiratory distress syndrome. Effective... 
Biomarkers | Predictive analytics | Mortality | ARDS
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2005, Volume 280, Issue 17, pp. 17286 - 17293
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, p. e0158865
Protein Kinase C (PKC) plays a significant role in thrombin-induced loss of endothelial cell (EC) barrier integrity; however, the existence of more than 10... 
SMOOTH-MUSCLE | ACTIVATION | CONTRACTION | PHOSPHORYLATION | PKC-DELTA | BISTRATENE-A | MULTIDISCIPLINARY SCIENCES | DYSFUNCTION | RHO-GTPASES | MYOSIN LIGHT-CHAIN | MICROVASCULAR PERMEABILITY | Lung - pathology | Gene Silencing - drug effects | Stress Fibers - drug effects | Humans | Enzyme Activation - drug effects | Lung - enzymology | Protein Kinase C-delta - metabolism | Stress Fibers - metabolism | Thrombin - pharmacology | Signal Transduction - drug effects | Models, Biological | rho GTP-Binding Proteins - metabolism | Acetophenones - pharmacology | Protein Kinase C-delta - antagonists & inhibitors | Myosin Light Chains - metabolism | Phosphorylation - drug effects | Benzopyrans - pharmacology | Endothelial Cells - pathology | Phosphoprotein Phosphatases | Protein Kinase C | Prevention | Isoenzymes | Lung diseases | Physiological aspects | Thrombin | Research | Protein kinases | Endothelium | Diabetic retinopathy | Cell culture | Phosphorylation | Protein kinase C | Homeostasis | Activation | Kinases | Positive feedback | Contraction | Modulators | Proteins | Physiology | Growth factors | Immunoglobulins | Pulmonary arteries | Rac1 protein | siRNA | Permeability | Pulmonary artery | Endothelial cells | Medicine | Studies | Signaling | Chemistry | DELTA protein | Lungs | Cytoskeleton | Sepsis | Guanosinetriphosphatase | Integrity
Journal Article
Journal Article
Journal Article
American Journal of Physiology: Lung Cellular and Molecular Physiology, ISSN 1040-0605, 11/2015, Volume 309, Issue 9, pp. L983 - L983
Inflammatory mediators released in acute lung injury (ALI) trigger the disruption of interendothelial junctions, leading to loss of vascular barrier function,... 
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0200916
Introduction Pseudogenes are paralogues of functional genes historically viewed as defunct due to either the lack of regulatory elements or the presence of... 
CELLS | 8Q24 | GENE | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | MOUSE | LIGHT-CHAIN-KINASE | PROMOTER | ENDOGENOUS RNA | EXPRESSION | VARIANT | Colon cancer | African Americans | Genetic aspects | Single nucleotide polymorphisms | Research | Health aspects | Risk factors
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 04/2017, Volume 135, Issue 16, pp. 1532 - 1546
Journal Article
by Sullivan, Patrick and Yuan, Maoli and Coleman, John and Destefano, Joanne and Zhang, Xinsheng and Yates, Nicole and Barouch, Dan and Ackerman, Margaret and Decamp, Allan and Alter, Galit and Tomaras, Georgia and Tomaras, Georgia and Montefiori, David and Montefiori, David and Rasmussen, Beth and Morrow, Gavin and Koff, Wayne and Kashuba, Angela and Kashuba, Angela and Mascola, John and Picker, Louis and Kent, Stephen and Selhorst, Philippe and Masson, Lindi and Ngandu, Nobubelo and Rademeyer, Cecilia and Karim, Quarraisha Abdool and Kijak, Gustavo and Barouch, Dan and Rasheed, Ata Ur and Havenar-Daughton, Colin and Pham, Matthew and Kovalenkov, Yevgeniy and Gumber, Sanjeev and Johnson, Matthew and Wrammert, Jens and Villinger, Francois and Haynes, Barton and Haynes, Barton and Fox, Christopher and Reed, Steve and Vasilakos, John and Tomai, Mark and Crotty, Shane and Ahmed, Rafi and Pulendran, Bali and Fukazawa, Yoshinori and Lifson, Jeffrey and Lifson, Jeffrey and Moore, Penny and Chatora, Kumbirai and Skorochod, Elisabeth and Madidi, Ngonidzashe and Gomez, Anabel and Ncube, Getrude and Sundaram, Maaya and Kretschmer, Steve and Pauthner, Matthias and Briney, Bryan and Lee, Jeong Hyun and Saye-Francisco, Karen and Hsueh, Jessica and Ramos, Alejandra and Le, Khoa and Jones, Meaghan and Jardine, Joseph and Bastidas, Raiza and Sarkar, Anita and Liang, Chi-Hui and Wilson, Ian and Ward, Andrew and Zhu, Jiang and Poignard, Pascal and Burton, Dennis and Krebs, Shelly and Law, Wiliam and Gift, Syna and Chenine, Agnes and Rolland, Morgane and Moody, M. Anthony and Jarosinski, Marissa and Georgiev, Ivelin and Chuang, Gwo-Yu and Chuang, Gwo-Yu and Asokan, Mangaiarkarasi and Bailer, Robert T and Cale, Evan M and Louder, Mark and Kwong, Peter D and Polonis, Victoria and Tovanabutra, Sodsai and Robb, Merlin and Mascola, John R and Wibmer, Constantinos Kurt and Wibmer, Constantinos Kurt and Madzorera, Vimbai S and Doria-Rose, Nicole A and Morris, Lynn and Moore, Penny L and Anthony, Colin and ...
AIDS Research and Human Retroviruses, ISSN 0889-2229, 10/2016, Volume 32, Issue S1, pp. 1 - 409
Journal Article
Critical Care Medicine, ISSN 0090-3493, 03/2014, Volume 42, Issue 3, pp. e189 - e199
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 11/2010, Volume 21, Issue 22, pp. 4042 - 4056
Journal Article