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Current Opinion in Pulmonary Medicine, ISSN 1070-5287, 05/2019, Volume 25, Issue 3, pp. 294 - 299
PURPOSE OF REVIEWPulmonary alveolar proteinosis (PAP) is characterized by the massive accumulation of lipoproteinaceous material within alveoli, which results... 
IMMUNITY | COLONY-STIMULATING FACTOR | INNATE | gene correction | pulmonary alveolar proteinosis | WHOLE LUNG LAVAGE | RECEPTOR-DEFICIENT MICE | RESPONSES | macrophages | BENEFIT | GM-CSF | RESPIRATORY SYSTEM | granulocyte-macrophage colony-stimulating factor | PPAR-GAMMA | induced pluripotent stem cells | MACROPHAGE DIFFERENTIATION
Journal Article
Nature Communications, ISSN 2041-1723, 06/2015, Volume 6, Issue 1, p. 7375
Pulmonary alveolar proteinosis (PAP) is a severe autoimmune disease caused by autoantibodies that neutralize GM-CSF resulting in impaired function of alveolar... 
B-CELLS | POTENT NEUTRALIZATION | MULTIDISCIPLINARY SCIENCES | DISEASE | STIMULATING FACTOR AUTOANTIBODIES | CYTOKINE | MUTATIONS | MONOCLONAL-ANTIBODIES | GAMMA AUTOANTIBODIES
Journal Article
Translational Research, ISSN 1931-5244, 2007, Volume 150, Issue 5, pp. 267 - 274
Journal Article
Respiratory Research, ISSN 1465-9921, 04/2014, Volume 15, Issue 1, pp. 43 - 43
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 11/2010, Volume 182, Issue 10, pp. 1292 - 1304
Rationale We identified a 6 year old girl with pulmonary alveolar proteinosis (PAP), impaired granulocyte macrophage colony stimulating factor (GM CSF)... 
Surfactant | Gm-csf receptor | Alveolar macrophage | Whole lung lavage | Genetic disease | alveolar macrophage | INTERLEUKIN-3 | COLONY-STIMULATING FACTOR | GM CSF | DISORDERS | COMMON BETA-SUBUNIT | DEFICIENT MICE | GM-CSF AUTOANTIBODIES | receptor | whole lung lavage | LUNG LAVAGE | GENE | RESPIRATORY SYSTEM | genetic disease | MACROPHAGE DIFFERENTIATION | surfactant | CRITICAL CARE MEDICINE | Humans | Genetic Diseases, Inborn - genetics | Child, Preschool | Infant | Male | Dyspnea - etiology | Receptors, Granulocyte Colony-Stimulating Factor - genetics | Genetic Diseases, Inborn - therapy | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Pulmonary Alveolar Proteinosis - genetics | Receptors, Granulocyte Colony-Stimulating Factor - blood | Female | Genetic Diseases, Inborn - etiology | Child | Genetic Diseases, Inborn - diagnosis | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Lung - pathology | Pulmonary Alveolar Proteinosis - therapy | Genotype | Disease Progression | Pulmonary Alveolar Proteinosis - pathology | Receptors, Granulocyte Colony-Stimulating Factor - physiology | Autoantibodies - physiology | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - physiology | Pedigree | Genetic Markers - genetics | Age of Onset | Mutation | Pulmonary Alveolar Proteinosis - diagnosis | F. Pediatrics and Lung Development | GM-CSF receptor
Journal Article
Clinical Chemistry, ISSN 0009-9147, 08/2008, Volume 54, Issue 8, pp. 1331 - 1338
Abstract Background: Individuals with severe deficiency in serum α1-antitrypsin (AAT) concentrations are at high risk for developing chronic obstructive... 
Journal Article
Expert Opinion on Orphan Drugs, ISSN 2167-8707, 03/2019, Volume 7, Issue 3, pp. 117 - 123
Introduction: Pulmonary alveolar proteinosis (PAP) is an ultra-rare syndrome the peculiarity of which is the accumulation of surfactant within the alveolar... 
whole lung lavage | Inhaled therapy | GM-CSF | pulmonary alveolar proteinosis | AUTOANTIBODIES | IMMUNITY | FACTOR INHALATION | COLONY-STIMULATING FACTOR | EFFICACY | WHOLE-LUNG LAVAGE | FACTOR THERAPY | SURFACTANT | DISEASE | PHARMACOLOGY & PHARMACY | OPEN-LABEL TRIAL
Journal Article
Intensive care medicine, ISSN 0342-4642, 2018, Volume 44, Issue 5, pp. 564 - 577
Journal Article
Orphanet Journal of Rare Diseases, ISSN 1750-1172, 2013, Volume 8, Issue 1, pp. 40 - 40
Journal Article