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Journal of Molecular Medicine, ISSN 0946-2716, 3/2013, Volume 91, Issue 3, pp. 311 - 321
Retinal and choroidal vascular diseases constitute the most common causes of moderate and severe vision loss in developed countries. They can be divided into... 
Human Genetics | Angiogenesis | Diabetic retinopathy | Biomedicine | Platelet-derived growth factor | Age-related macular degeneration | Internal Medicine | Molecular Medicine | Hypoxia-inducible factor-1 | Vascular endothelial growth factor | MEDICINE, RESEARCH & EXPERIMENTAL | INCREASED EXPRESSION | MACULAR DEGENERATION | RETINAL ANGIOMATOUS PROLIFERATION | EPITHELIUM-DERIVED FACTOR | MURINE MODEL | SUPPRESSES CHOROIDAL NEOVASCULARIZATION | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | IN-VIVO | GENETICS & HEREDITY | TUMOR-GROWTH | ENDOTHELIAL GROWTH-FACTOR | Eye - metabolism | Macular Degeneration - physiopathology | Proto-Oncogene Proteins c-sis - metabolism | Retinal Vessels - metabolism | Humans | Clinical Trials as Topic | Retinal Neovascularization - metabolism | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-2 - metabolism | Choroidal Neovascularization - physiopathology | Macular Degeneration - metabolism | Choroidal Neovascularization - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Retinal Vessels - physiopathology | Retinal Neovascularization - physiopathology | Eye - physiopathology | Macular degeneration | Physiological aspects | Development and progression | Genetic aspects | DNA binding proteins | Research | Neovascularization | platelet-derived growth factor | diabetic retinopathy | age-related macular degeneration | vascular endothelial growth factor | hypoxia-inducible factor-1
Journal Article
by Wei Chen and Dwight Stambolian and Albert O. Edwards and Kari E. Branham and Mohammad Othman and Johanna Jakobsdottir and Nirubol Tosakulwong and Margaret A. Pericak-Vance and Peter A. Campochiaro and Michael L. Klein and Perciliz L. Tan and Yvette P. Conley and Atsuhiro Kanda and Laura Kopplin and Yanming Li and Katherine J. Augustaitis and Athanasios J. Karoukis and William K. Scott and Anita Agarwal and Jaclyn L. Kovach and Stephen G. Schwartz and Eric A. Postel and Matthew Brooks and Keith H. Baratz and William L. Brown and Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group and Alexander J. Brucker and Anton Orlin and Gary Brown and Allen Ho and Carl Regillo and Larry Donoso and Lifeng Tian and Brian Kaderli and Dexter Hadley and Stephanie A. Hagstrom and Neal S. Peachey and Ronald Klein and Barbara E. K. Klein and Norimoto Gotoh and Kenji Yamashiro and Frederick Ferris and Jesen A. Fagerness and Robyn Reynolds and Lindsay A. Farrer and Ivana K. Kim and Joan W. Miller and Marta Cortón and Angel Carracedo and Manuel Sanchez-Salorio and Elizabeth W. Pugh and Kimberly F. Doheny and Maria Brion and Margaret M. DeAngelis and Daniel E. Weeks and Donald J. Zack and Emily Y. Chew and John R. Heckenlively and Nagahisa Yoshimura and Sudha K. Iyengar and Peter J. Francis and Nicholas Katsanis and Johanna M. Seddon and Jonathan L. Haines and Michael B. Gorin and Gonçalo R. Abecasis and Anand Swaroop and Mark T. Keating and Complications Age-Related Macular and Complications of Age-Related Macular Degeneration Prevention Trial Research Group and Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2010, Volume 107, Issue 16, pp. 7401 - 7406
Journal Article
Progress in Retinal and Eye Research, ISSN 1350-9462, 11/2015, Volume 49, pp. 67 - 81
There are two major types of ocular neovascularization that affect the retina, retinal neovascularization (NV) and subretinal or choroidal NV. Retinal NV... 
Angiogenesis | Diabetic retinopathy | Platelet-derived growth factor | Age-related macular degeneration | TIE2 | Angiopoietins | Vascular endothelial-protein tyrosine phosphatase | Hypoxia-inducible factor-1 | Vascular endothelial growth factor | OCCLUSION 12-MONTH OUTCOMES | PROLIFERATIVE RETINOPATHY | FACTOR VEGF | SUBRETINAL NEOVASCULARIZATION | OCULAR NEOVASCULARIZATION | EPITHELIUM-DERIVED FACTOR | IN-VIVO | OPHTHALMOLOGY | DIABETIC MACULAR EDEMA | SIGNAL-TRANSDUCTION PATHWAY | ENDOTHELIAL GROWTH-FACTOR | Choroid Diseases - metabolism | Humans | Retinal Diseases - metabolism | Choroid Diseases - etiology | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-2 - metabolism | Hypoxia-Inducible Factor 1 - metabolism | Neovascularization, Pathologic - etiology | Intercellular Signaling Peptides and Proteins - metabolism | Animals | Choroid Diseases - drug therapy | Retinal Diseases - etiology | Angiogenesis Inhibitors - therapeutic use | Mice | Neovascularization, Pathologic - metabolism | Retinal Diseases - drug therapy | Disease Models, Animal | Macular degeneration | Medical colleges | Analysis | Development and progression | Neovascularization | Ophthalmology | vascular endothelial growth factor | angiopoietins | hypoxia-inducible factor-1 | vascular endothelial-protein tyrosine phosphatase | platelet-derived growth factor | diabetic retinopathy | age-related macular degeneration
Journal Article
by Fritsche, Lars G and Chen, Wei and Schu, Matthew and Yaspan, Brian L and Yu, Yi and Thorleifsson, Gudmar and Zack, Donald J and Arakawa, Satoshi and Cipriani, Valentina and Ripke, Stephan and Igo, Robert P and Buitendijk, Gabriëlle H. S and Sim, Xueling and Weeks, Daniel E and Guymer, Robyn H and Merriam, Joanna E and Francis, Peter J and Hannum, Gregory and Agarwal, Anita and Armbrecht, Ana Maria and Audo, Isabelle and Aung, Tin and Barile, Gaetano R and Benchaboune, Mustapha and Bird, Alan C and Bishop, Paul N and Branham, Kari E and Brooks, Matthew and Brucker, Alexander J and Cade, William H and Cain, Melinda S and Campochiaro, Peter A and Chan, Chi-Chao and Cheng, Ching-Yu and Chew, Emily Y and Chin, Kimberly A and Chowers, Itay and Clayton, David G and Cojocaru, Radu and Conley, Yvette P and Cornes, Belinda K and Daly, Mark J and Dhillon, Baljean and Edwards, Albert O and Evangelou, Evangelos and Fagerness, Jesen and Ferreyra, Henry A and Friedman, James S and Geirsdottir, Asbjorg and George, Ronnie J and Gieger, Christian and Gupta, Neel and Hagstrom, Stephanie A and Harding, Simon P and Haritoglou, Christos and Heckenlively, John R and Holz, Frank G and Hughes, Guy and Ioannidis, John P. A and Ishibashi, Tatsuro and Joseph, Peronne and Jun, Gyungah and Kamatani, Yoichiro and Katsanis, Nicholas and N Keilhauer, Claudia and Khan, Jane C and Kim, Ivana K and Kiyohara, Yutaka and Klein, Barbara E. K and Klein, Ronald and Kovach, Jaclyn L and Kozak, Igor and Lee, Clara J and Lee, Kristine E and Lichtner, Peter and Lotery, Andrew J and Meitinger, Thomas and Mitchell, Paul and Mohand-Saïd, Saddek and Moore, Anthony T and Morgan, Denise J and Morrison, Margaux A and Myers, Chelsea E and Naj, Adam C and Nakamura, Yusuke and Okada, Yukinori and Orlin, Anton and Ortube, M Carolina and Othman, Mohammad I and Pappas, Chris and Park, Kyu Hyung and Pauer, Gayle J. T and Peachey, Neal S and Poch, Olivier and Priya, Rinki Ratna and Reynolds, Robyn and Richardson, Andrea J and Ripp, Raymond and Rudolph, Guenther and Ryu, Euijung and ... and AMD Gene Consortium and The AMD Gene Consortium
Nature Genetics, ISSN 1061-4036, 04/2013, Volume 45, Issue 4, pp. 433 - 439
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JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 08/2019, Volume 129, Issue 8, pp. 3029 - 3031
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The New England Journal of Medicine, ISSN 0028-4793, 10/2008, Volume 359, Issue 14, pp. 1456 - 1463
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Ophthalmology, ISSN 0161-6420, 2009, Volume 116, Issue 11, pp. 2141 - 2148.e1
Journal Article
Angiogenesis, ISSN 0969-6970, 7/2014, Volume 17, Issue 3, pp. 553 - 562
Hypoxia-inducible factor-1 (HIF-1) plays an important role in retinal and subretinal neovascularization (NV). Increased levels of HIF-1 cause increased... 
Diabetic retinopathy | HIF-1 | Biomedicine | DARPin | Age-related macular degeneration | Cancer Research | Oncology | Ophthalmology | Cardiology | Biomedicine general | Cell Biology | DARPINS | MODEL | CHOROIDAL NEOVASCULARIZATION | RETINOPATHY | PERIPHERAL VASCULAR DISEASE | MICE | PROTEINS | PROMOTER | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | NIH 3T3 Cells | Retinal Detachment - pathology | Recombinant Fusion Proteins - pharmacology | Recombinant Fusion Proteins - therapeutic use | Vascular Endothelial Growth Factor A - metabolism | Retinal Detachment - drug therapy | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Choroidal Neovascularization - drug therapy | Choroidal Neovascularization - pathology | Ischemia - complications | Protein Binding - drug effects | Receptors, LDL - deficiency | Ischemia - pathology | Recombinant Fusion Proteins - administration & dosage | Proto-Oncogene Proteins c-sis - metabolism | Mice, Inbred C57BL | Rats | Receptors, LDL - metabolism | Mice, Transgenic | Animals | Opsins - metabolism | Mice | Retinal Detachment - prevention & control | Retinal Neovascularization - drug therapy | Injections, Intraocular | Retinal Neovascularization - pathology | Proto-Oncogene Proteins c-sis - antagonists & inhibitors | Physiological aspects | Platelet-derived growth factor | Research | Neovascularization | Vascular endothelial growth factor | Genes
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