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Journal Article
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7456, pp. 50 - 54
53BP1 (also called TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand-break (DSB) repair by... 
CRB2 | RECRUITMENT | FISSION YEAST | METHYLATION | CHROMATIN | DEPENDENT RESPONSE | RESECTION | MULTIDISCIPLINARY SCIENCES | SITES | DOUBLE-STRAND BREAKS | CLASS-SWITCH RECOMBINATION | Schizosaccharomyces pombe Proteins - chemistry | Histones - chemistry | Nucleosomes - chemistry | Humans | Ubiquitin - metabolism | Molecular Sequence Data | Male | Intracellular Signaling Peptides and Proteins - metabolism | DNA Breaks, Double-Stranded | DNA-Binding Proteins - deficiency | Cell Cycle Proteins - chemistry | Intracellular Signaling Peptides and Proteins - deficiency | Ubiquitination | Schizosaccharomyces pombe Proteins - metabolism | Female | Lysine - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Schizosaccharomyces | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Signal Transduction | Cell Cycle Proteins - metabolism | Nucleosomes - metabolism | Mutant Proteins - metabolism | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Chromosomal Proteins, Non-Histone - deficiency | Amino Acid Motifs | Chromosomal Proteins, Non-Histone - genetics | Animals | Intracellular Signaling Peptides and Proteins - chemistry | Mutant Proteins - chemistry | Protein Binding | Mice | DNA Damage | Histones - metabolism | Tumor Suppressor p53-Binding Protein 1 | Chromosomal Proteins, Non-Histone - chemistry | Ubiquitin | Research | Properties | DNA repair | DNA damage | Proteins | DNA methylation | Mutation | Experiments | Recruitment | Index Medicus
Journal Article
PLoS Genetics, ISSN 1553-7390, 03/2014, Volume 10, Issue 3
  Histone ubiquitinations are critical for the activation of the DNA damage response (DDR). In particular, RNF168 and RING1B/BMI1 function in the DDR by... 
Mutation | Kinases | DNA repair | DNA damage | Cell cycle
Journal Article
Journal Article
Nature, ISSN 0028-0836, 7/2013, Volume 499, Issue 7456, pp. 50 - 54
53BP1 (TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand break (DSB) repair by non-homologous end... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2005, Volume 102, Issue 52, pp. 18902 - 18907
Journal Article
Nature Biotechnology, ISSN 1087-0156, 01/2018, Volume 36, Issue 1, pp. 95 - 102
Journal Article
Nature Communications, ISSN 2041-1723, 08/2014, Volume 5, Issue 1, pp. 4202 - 4202
Endoplasmic reticulum (ER) stress activates the unfolded protein response and its dysfunction is linked to multiple diseases. The stress transducer IRE1 alpha... 
KINASE-ACTIVITY | ACTIVATION | UNFOLDED PROTEIN RESPONSE | MESSENGER-RNA | ER STRESS | MULTIDISCIPLINARY SCIENCES | IRE1-ALPHA | ENDOPLASMIC-RETICULUM STRESS | TRANSCRIPTION FACTOR | MAMMALIAN-CELLS | TRANSMEMBRANE PROTEIN | Small Molecule Libraries - pharmacology | Plasmacytoma - drug therapy | Humans | Coumarins - chemistry | Crystallography, X-Ray | Cell Line, Tumor - drug effects | Plasmacytoma - pathology | Structure-Activity Relationship | Ribonucleases - metabolism | DNA Mutational Analysis | Aldehydes - pharmacology | Enzyme Inhibitors - chemistry | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Membrane Proteins - metabolism | Molecular Structure | Binding Sites | Protein-Serine-Threonine Kinases - metabolism | Catalytic Domain | Benzaldehydes - chemistry | Enzyme Inhibitors - metabolism | Membrane Proteins - genetics | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Morpholines - pharmacology | Benzaldehydes - pharmacology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Regulatory Factor X Transcription Factors | Morpholines - chemistry | Coumarins - pharmacology | Small Molecule Libraries - chemistry | Membrane Proteins - antagonists & inhibitors | Membrane Proteins - chemistry | Protein Conformation | Protein-Serine-Threonine Kinases - chemistry | CD59 Antigens - metabolism | Aldehydes - chemistry | Index Medicus
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2004, Volume 126, Issue 35, pp. 10848 - 10849
The hammerhead ribozyme is a small RNA motif that catalyzes the cleavage and ligation of RNA. The well-studied minimal hammerhead motif is inactive under... 
ELEMENTS | RNA | CHEMISTRY, MULTIDISCIPLINARY | SELF-CLEAVAGE | Magnesium - chemistry | Animals | RNA, Catalytic - metabolism | Magnesium - metabolism | Schistosoma - enzymology | Catalysis | Kinetics | RNA, Catalytic - chemistry | Schistosoma - genetics | Hydrogen-Ion Concentration | Research | Chemical properties | Catalytic RNA | Dynamics | Index Medicus
Journal Article
Journal Article